Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 74

1.

Proteomic Analysis of Zn Depletion/Repletion in the Hormone-Secreting Thyroid Follicular Cell Line FRTL-5.

Guantario B, Capolupo A, Monti MC, Leoni G, Ranaldi G, Tosco A, Marzullo L, Murgia C, Perozzi G.

Nutrients. 2018 Dec 14;10(12). pii: E1981. doi: 10.3390/nu10121981.

2.

Annexin A1 May Induce Pancreatic Cancer Progression as a Key Player of Extracellular Vesicles Effects as Evidenced in the In Vitro MIA PaCa-2 Model System.

Pessolano E, Belvedere R, Bizzarro V, Franco P, Marco I, Porta A, Tosco A, Parente L, Perretti M, Petrella A.

Int J Mol Sci. 2018 Dec 4;19(12). pii: E3878. doi: 10.3390/ijms19123878.

3.

A pathogenic role for cystic fibrosis transmembrane conductance regulator in celiac disease.

Villella VR, Venerando A, Cozza G, Esposito S, Ferrari E, Monzani R, Spinella MC, Oikonomou V, Renga G, Tosco A, Rossin F, Guido S, Silano M, Garaci E, Chao YK, Grimm C, Luciani A, Romani L, Piacentini M, Raia V, Kroemer G, Maiuri L.

EMBO J. 2019 Jan 15;38(2). pii: e100101. doi: 10.15252/embj.2018100101. Epub 2018 Nov 29.

4.

TFF1 Promotes EMT-Like Changes through an Auto-Induction Mechanism.

Romano E, Vllahu M, Bizzarro V, Belvedere R, Esposito R, Petrella A, Tosco A.

Int J Mol Sci. 2018 Jul 11;19(7). pii: E2018. doi: 10.3390/ijms19072018.

5.

Intra-individual biological variation in sweat chloride concentrations in CF, CFTR dysfunction, and healthy pediatric subjects.

Cirilli N, Raia V, Rocco I, De Gregorio F, Tosco A, Salvadori L, Sepe AO, Buzzetti R, Minicuci N, Castaldo G.

Pediatr Pulmonol. 2018 Jun;53(6):728-734. doi: 10.1002/ppul.23992. Epub 2018 Apr 2.

PMID:
29611353
6.

May the new suggested lower borderline limit of sweat chloride impact the diagnostic process for cystic fibrosis?

Cirilli N, Braggion C, Mergni G, Polizzi AM, Padoan R, Sirianni S, Seia M, Raia V, Tosco A, Pisi G, Spaggiari C, Quattromano E, Bignamini E, Brandino D, Bella S, Argentini R; ICFS Sweat Test Working Group.

J Pediatr. 2018 Mar;194:261-262. doi: 10.1016/j.jpeds.2017.11.053. Epub 2018 Jan 17. No abstract available.

PMID:
29352589
7.

Gastric TFF1 Expression from Acute to Chronic Helicobacter Infection.

Esposito R, Morello S, Vllahu M, Eletto D, Porta A, Tosco A.

Front Cell Infect Microbiol. 2017 Oct 9;7:434. doi: 10.3389/fcimb.2017.00434. eCollection 2017.

8.

Inhibition of Wnt/β-Catenin pathway and Histone acetyltransferase activity by Rimonabant: a therapeutic target for colon cancer.

Proto MC, Fiore D, Piscopo C, Franceschelli S, Bizzarro V, Laezza C, Lauro G, Feoli A, Tosco A, Bifulco G, Sbardella G, Bifulco M, Gazzerro P.

Sci Rep. 2017 Sep 15;7(1):11678. doi: 10.1038/s41598-017-11688-x.

9.

Proteasome as a New Target for Bio-Inspired Benzo[k,l]xanthene Lignans.

Capolupo A, Tosco A, Mozzicafreddo M, Tringali C, Cardullo N, Monti MC, Casapullo A.

Chemistry. 2017 Jun 22;23(35):8371-8374. doi: 10.1002/chem.201701095. Epub 2017 Jun 1.

PMID:
28485479
10.

Lung structure and function similarities between primary ciliary dyskinesia and mild cystic fibrosis: a pilot study.

Maglione M, Montella S, Mollica C, Carnovale V, Iacotucci P, De Gregorio F, Tosco A, Cervasio M, Raia V, Santamaria F.

Ital J Pediatr. 2017 Apr 12;43(1):34. doi: 10.1186/s13052-017-0351-2.

11.

Determination of Gymnemic Acid I as a Protein Biosynthesis Inhibitor Using Chemical Proteomics.

Capolupo A, Esposito R, Zampella A, Festa C, Riccio R, Casapullo A, Tosco A, Monti MC.

J Nat Prod. 2017 Apr 28;80(4):909-915. doi: 10.1021/acs.jnatprod.6b00793. Epub 2017 Mar 3.

PMID:
28256837
12.

Cysteamine re-establishes the clearance of Pseudomonas aeruginosa by macrophages bearing the cystic fibrosis-relevant F508del-CFTR mutation.

Ferrari E, Monzani R, Villella VR, Esposito S, Saluzzo F, Rossin F, D'Eletto M, Tosco A, De Gregorio F, Izzo V, Maiuri MC, Kroemer G, Raia V, Maiuri L.

Cell Death Dis. 2017 Jan 12;8(1):e2544. doi: 10.1038/cddis.2016.476.

13.

β-Boswellic acid, a bioactive substance used in food supplements, inhibits protein synthesis by targeting the ribosomal machinery.

Casapullo A, Cassiano C, Capolupo A, Del Gaudio F, Esposito R, Tosco A, Riccio R, Monti MC.

J Mass Spectrom. 2016 Sep;51(9):821-7. doi: 10.1002/jms.3819.

PMID:
27460774
14.

A novel treatment of cystic fibrosis acting on-target: cysteamine plus epigallocatechin gallate for the autophagy-dependent rescue of class II-mutated CFTR.

Tosco A, De Gregorio F, Esposito S, De Stefano D, Sana I, Ferrari E, Sepe A, Salvadori L, Buonpensiero P, Di Pasqua A, Grassia R, Leone CA, Guido S, De Rosa G, Lusa S, Bona G, Stoll G, Maiuri MC, Mehta A, Kroemer G, Maiuri L, Raia V.

Cell Death Differ. 2017 Jul;24(7):1305. doi: 10.1038/cdd.2016.43. Epub 2016 Jul 22.

15.

A novel treatment of cystic fibrosis acting on-target: cysteamine plus epigallocatechin gallate for the autophagy-dependent rescue of class II-mutated CFTR.

Tosco A, De Gregorio F, Esposito S, De Stefano D, Sana I, Ferrari E, Sepe A, Salvadori L, Buonpensiero P, Di Pasqua A, Grassia R, Leone CA, Guido S, De Rosa G, Lusa S, Bona G, Stoll G, Maiuri MC, Mehta A, Kroemer G, Maiuri L, Raia V.

Cell Death Differ. 2016 Aug;23(8):1380-93. doi: 10.1038/cdd.2016.22. Epub 2016 Apr 1. Erratum in: Cell Death Differ. 2017 Jul;24(7):1305.

16.

Manipulating proteostasis to repair the F508del-CFTR defect in cystic fibrosis.

Esposito S, Tosco A, Villella VR, Raia V, Kroemer G, Maiuri L.

Mol Cell Pediatr. 2016 Dec;3(1):13. doi: 10.1186/s40348-016-0040-z. Epub 2016 Mar 14. Review.

17.

In Cell Interactome of Oleocanthal, an Extra Virgin Olive Oil Bioactive Component.

Cassiano C, Casapullo A, Tosco A, Monti MC, Riccio R.

Nat Prod Commun. 2015 Jun;10(6):1013-6.

PMID:
26197539
18.

Streptococcus pneumoniae oropharyngeal colonization in children and adolescents with cystic fibrosis.

Esposito S, Colombo C, Tosco A, Montemitro E, Volpi S, Ruggiero L, Lelii M, Bisogno A, Pelucchi C, Principi N; Italian Pneumococcal Study Group on Cystic Fibrosis.

J Cyst Fibros. 2016 May;15(3):366-71. doi: 10.1016/j.jcf.2015.05.008. Epub 2015 Jun 3.

19.

Identification and mechanism of action analysis of the new PARP-1 inhibitor 2″-hydroxygenkwanol A.

Dal Piaz F, Ferro P, Vassallo A, Vasaturo M, Forte G, Chini MG, Bifulco G, Tosco A, De Tommasi N.

Biochim Biophys Acta. 2015 Sep;1850(9):1806-14. doi: 10.1016/j.bbagen.2015.05.014. Epub 2015 May 19.

PMID:
25999161
20.

A novel cell-permeable, selective, and noncompetitive inhibitor of KAT3 histone acetyltransferases from a combined molecular pruning/classical isosterism approach.

Milite C, Feoli A, Sasaki K, La Pietra V, Balzano AL, Marinelli L, Mai A, Novellino E, Castellano S, Tosco A, Sbardella G.

J Med Chem. 2015 Mar 26;58(6):2779-98. doi: 10.1021/jm5019687. Epub 2015 Mar 10.

PMID:
25730130
21.

Discriminant score for celiac disease based on immunohistochemical analysis of duodenal biopsies.

Tosco A, Maglio M, Paparo F, Greco L, Troncone R, Auricchio R.

J Pediatr Gastroenterol Nutr. 2015 May;60(5):621-5. doi: 10.1097/MPG.0000000000000675.

PMID:
25514620
22.

Theonellasterone, a steroidal metabolite isolated from a Theonella sponge, protects peroxiredoxin-1 from oxidative stress reactions.

Margarucci L, Monti MC, Tosco A, Esposito R, Zampella A, Sepe V, Mozzicafreddo M, Riccio R, Casapullo A.

Chem Commun (Camb). 2015 Jan 31;51(9):1591-3. doi: 10.1039/c4cc09205h.

PMID:
25503482
23.

Trefoil Factor 1 is involved in gastric cell copper homeostasis.

Esposito R, Montefusco S, Ferro P, Monti MC, Baldantoni D, Tosco A, Marzullo L.

Int J Biochem Cell Biol. 2015 Feb;59:30-40. doi: 10.1016/j.biocel.2014.11.014. Epub 2014 Dec 5.

PMID:
25486181
24.

Randomized, single blind, controlled trial of inhaled glutathione vs placebo in patients with cystic fibrosis.

Calabrese C, Tosco A, Abete P, Carnovale V, Basile C, Magliocca A, Quattrucci S, De Sanctis S, Alatri F, Mazzarella G, De Pietro L, Turino C, Melillo E, Buonpensiero P, Di Pasqua A, Raia V.

J Cyst Fibros. 2015 Mar;14(2):203-10. doi: 10.1016/j.jcf.2014.09.014. Epub 2014 Nov 4.

25.

Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation.

De Stefano D, Villella VR, Esposito S, Tosco A, Sepe A, De Gregorio F, Salvadori L, Grassia R, Leone CA, De Rosa G, Maiuri MC, Pettoello-Mantovani M, Guido S, Bossi A, Zolin A, Venerando A, Pinna LA, Mehta A, Bona G, Kroemer G, Maiuri L, Raia V.

Autophagy. 2014;10(11):2053-74. doi: 10.4161/15548627.2014.973737.

26.

Identification of structural features of 2-alkylidene-1,3-dicarbonyl derivatives that induce inhibition and/or activation of histone acetyltransferases KAT3B/p300 and KAT2B/PCAF.

Castellano S, Milite C, Feoli A, Viviano M, Mai A, Novellino E, Tosco A, Sbardella G.

ChemMedChem. 2015 Jan;10(1):144-57. doi: 10.1002/cmdc.201402371. Epub 2014 Oct 21.

PMID:
25333655
27.

Structural evidence of N6-isopentenyladenosine as a new ligand of farnesyl pyrophosphate synthase.

Scrima M, Lauro G, Grimaldi M, Di Marino S, Tosco A, Picardi P, Gazzerro P, Riccio R, Novellino E, Bifulco M, Bifulco G, D'Ursi AM.

J Med Chem. 2014 Sep 25;57(18):7798-803. doi: 10.1021/jm500869x. Epub 2014 Sep 15.

PMID:
25184810
28.

Potential celiac children: 9-year follow-up on a gluten-containing diet.

Auricchio R, Tosco A, Piccolo E, Galatola M, Izzo V, Maglio M, Paparo F, Troncone R, Greco L.

Am J Gastroenterol. 2014 Jun;109(6):913-21. doi: 10.1038/ajg.2014.77. Epub 2014 Apr 22.

PMID:
24777149
29.

Intestinal titres of anti-tissue transglutaminase 2 antibodies correlate positively with mucosal damage degree and inversely with gluten-free diet duration in coeliac disease.

Tosco A, Auricchio R, Aitoro R, Ponticelli D, Primario M, Miele E, Rotondi Aufiero V, Discepolo V, Greco L, Troncone R, Maglio M.

Clin Exp Immunol. 2014 Sep;177(3):611-7. doi: 10.1111/cei.12366.

30.

In cell scalaradial interactome profiling using a bio-orthogonal clickable probe.

Cassiano C, Margarucci L, Esposito R, Riccio R, Tosco A, Casapullo A, Monti MC.

Chem Commun (Camb). 2014 Jun 7;50(45):6043-5. doi: 10.1039/c4cc00989d. Epub 2014 Apr 28.

PMID:
24769547
31.

Prediction of acute pancreatitis risk based on PIP score in children with cystic fibrosis.

Terlizzi V, Tosco A, Tomaiuolo R, Sepe A, Amato N, Casale A, Mercogliano C, De Gregorio F, Improta F, Elce A, Castaldo G, Raia V.

J Cyst Fibros. 2014 Sep;13(5):579-84. doi: 10.1016/j.jcf.2014.01.007. Epub 2014 Feb 11.

32.

N-Formyl-7-amino-11-cycloamphilectene, a marine sponge metabolite, binds to tubulin and modulates microtubule depolymerization.

Margarucci L, Monti MC, Esposito R, Tosco A, Hamel E, Riccio R, Casapullo A.

Mol Biosyst. 2014 Apr;10(4):862-7. doi: 10.1039/c3mb70315k. Epub 2014 Feb 4.

33.

Role of Arabidopsis UV RESISTANCE LOCUS 8 in plant growth reduction under osmotic stress and low levels of UV-B.

Fasano R, Gonzalez N, Tosco A, Dal Piaz F, Docimo T, Serrano R, Grillo S, Leone A, Inzé D.

Mol Plant. 2014 May;7(5):773-91. doi: 10.1093/mp/ssu002. Epub 2014 Jan 10.

34.

Copper promotes TFF1-mediated Helicobacter pylori colonization.

Montefusco S, Esposito R, D'Andrea L, Monti MC, Dunne C, Dolan B, Tosco A, Marzullo L, Clyne M.

PLoS One. 2013 Nov 13;8(11):e79455. doi: 10.1371/journal.pone.0079455. eCollection 2013.

35.

Heteronemin, a marine sponge terpenoid, targets TDP-43, a key factor in several neurodegenerative disorders.

Cassiano C, Esposito R, Tosco A, Zampella A, D'Auria MV, Riccio R, Casapullo A, Monti MC.

Chem Commun (Camb). 2014 Jan 14;50(4):406-8. doi: 10.1039/c3cc45454a.

PMID:
23963116
36.

Chemical proteomics-driven discovery of oleocanthal as an Hsp90 inhibitor.

Margarucci L, Monti MC, Cassiano C, Mozzicafreddo M, Angeletti M, Riccio R, Tosco A, Casapullo A.

Chem Commun (Camb). 2013 Jul 4;49(52):5844-6. doi: 10.1039/c3cc41858h. Epub 2013 May 24.

PMID:
23703283
37.

Differential in gel electrophoresis (DIGE) comparative proteomic analysis of macrophages cell cultures in response to perthamide C treatment.

Vilasi A, Monti MC, Tosco A, De Marino S, Margarucci L, Riccio R, Casapullo A.

Mar Drugs. 2013 Apr 17;11(4):1288-99. doi: 10.3390/md11041288.

38.

Intestinal anti-tissue transglutaminase antibodies in potential coeliac disease.

Tosco A, Aitoro R, Auricchio R, Ponticelli D, Miele E, Paparo F, Greco L, Troncone R, Maglio M.

Clin Exp Immunol. 2013 Jan;171(1):69-75. doi: 10.1111/j.1365-2249.2012.04673.x.

39.

Identification of small-molecule enhancers of arginine methylation catalyzed by coactivator-associated arginine methyltransferase 1.

Castellano S, Spannhoff A, Milite C, Dal Piaz F, Cheng D, Tosco A, Viviano M, Yamani A, Cianciulli A, Sala M, Cura V, Cavarelli J, Novellino E, Mai A, Bedford MT, Sbardella G.

J Med Chem. 2012 Nov 26;55(22):9875-90. doi: 10.1021/jm301097p. Epub 2012 Nov 2.

40.

The inactivation mechanism of human group IIA phospholipase A(2) by Scalaradial.

Margarucci L, Monti MC, Chini MG, Tosco A, Riccio R, Bifulco G, Casapullo A.

Chembiochem. 2012 Oct 15;13(15):2259-64. doi: 10.1002/cbic.201200453. Epub 2012 Sep 24.

PMID:
23008213
41.

A chemical proteomics approach reveals Hsp27 as a target for proapoptotic clerodane diterpenes.

Faiella L, Piaz FD, Bisio A, Tosco A, De Tommasi N.

Mol Biosyst. 2012 Oct;8(10):2637-44. doi: 10.1039/c2mb25171j.

PMID:
22802135
42.

Modulation of proteasome machinery by natural and synthetic analogues of the marine bioactive compound petrosaspongiolide M.

Margarucci L, Tosco A, De Simone R, Riccio R, Monti MC, Casapullo A.

Chembiochem. 2012 May 7;13(7):982-6. doi: 10.1002/cbic.201200113. Epub 2012 Mar 21.

PMID:
22438326
43.

New insights on the interaction mechanism between tau protein and oleocanthal, an extra-virgin olive-oil bioactive component.

Monti MC, Margarucci L, Tosco A, Riccio R, Casapullo A.

Food Funct. 2011 Jul;2(7):423-8. doi: 10.1039/c1fo10064e. Epub 2011 Jul 7.

PMID:
21894330
44.

Psychological distress in men with prostate cancer receiving adjuvant androgen-deprivation therapy.

Saini A, Berruti A, Cracco C, Sguazzotti E, Porpiglia F, Russo L, Bertaglia V, Picci RL, Negro M, Tosco A, Campagna S, Scarpa RM, Dogliotti L, Furlan PM, Ostacoli L.

Urol Oncol. 2013 Apr;31(3):352-8. doi: 10.1016/j.urolonc.2011.02.005. Epub 2011 Jul 30.

45.

Potential celiac patients: a model of celiac disease pathogenesis.

Sperandeo MP, Tosco A, Izzo V, Tucci F, Troncone R, Auricchio R, Romanos J, Trynka G, Auricchio S, Jabri B, Greco L.

PLoS One. 2011;6(7):e21281. doi: 10.1371/journal.pone.0021281. Epub 2011 Jul 8.

46.

Intestinal deposits of anti-tissue transglutaminase IgA in childhood celiac disease.

Maglio M, Tosco A, Auricchio R, Paparo F, Colicchio B, Miele E, Rapacciuolo L, Troncone R.

Dig Liver Dis. 2011 Aug;43(8):604-8. doi: 10.1016/j.dld.2011.01.015. Epub 2011 Feb 20.

PMID:
21342796
47.

Modulation of the activity of histone acetyltransferases by long chain alkylidenemalonates (LoCAMs).

Milite C, Castellano S, Benedetti R, Tosco A, Ciliberti C, Vicidomini C, Boully L, Franci G, Altucci L, Mai A, Sbardella G.

Bioorg Med Chem. 2011 Jun 15;19(12):3690-701. doi: 10.1016/j.bmc.2011.01.013. Epub 2011 Jan 14.

PMID:
21292492
48.

Natural history of potential celiac disease in children.

Tosco A, Salvati VM, Auricchio R, Maglio M, Borrelli M, Coruzzo A, Paparo F, Boffardi M, Esposito A, D'Adamo G, Malamisura B, Greco L, Troncone R.

Clin Gastroenterol Hepatol. 2011 Apr;9(4):320-5; quiz e36. doi: 10.1016/j.cgh.2010.09.006. Epub 2010 Sep 17.

PMID:
20851213
49.

Chemical proteomics discloses petrosapongiolide M, an antiinflammatory marine sesterterpene, as a proteasome inhibitor.

Margarucci L, Monti MC, Tosco A, Riccio R, Casapullo A.

Angew Chem Int Ed Engl. 2010 May 25;49(23):3960-3. doi: 10.1002/anie.200907153. No abstract available.

PMID:
20376869
50.

The identification of a novel natural activator of p300 histone acetyltranferase provides new insights into the modulation mechanism of this enzyme.

Dal Piaz F, Tosco A, Eletto D, Piccinelli AL, Moltedo O, Franceschelli S, Sbardella G, Remondelli P, Rastrelli L, Vesci L, Pisano C, De Tommasi N.

Chembiochem. 2010 Apr 12;11(6):818-27. doi: 10.1002/cbic.200900721.

PMID:
20373302

Supplemental Content

Support Center