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Items: 1 to 50 of 61

1.

Fibroblasts and Their Pathological Functions in the Fibrosis of Aortic Valve Sclerosis and Atherosclerosis.

Singh S, Torzewski M.

Biomolecules. 2019 Sep 10;9(9). pii: E472. doi: 10.3390/biom9090472. Review.

2.

Role of p38 MAPK in Atherosclerosis and Aortic Valve Sclerosis.

Reustle A, Torzewski M.

Int J Mol Sci. 2018 Nov 27;19(12). pii: E3761. doi: 10.3390/ijms19123761. Review.

3.

Lipoprotein(a) Associated Molecules are Prominent Components in Plasma and Valve Leaflets in Calcific Aortic Valve Stenosis.

Torzewski M, Ravandi A, Yeang C, Edel A, Bhindi R, Kath S, Twardowski L, Schmid J, Yang X, Franke UFW, Witztum JL, Tsimikas S.

JACC Basic Transl Sci. 2017 Jun;2(3):229-240. doi: 10.1016/j.jacbts.2017.02.004. Epub 2017 Jun 26.

4.

Enzymatically modified LDL, atherosclerosis and beyond: paving the way to acceptance.

Torzewski M.

Front Biosci (Landmark Ed). 2018 Jan 1;23:1257-1271. Review.

PMID:
28930598
5.

Increasing Morbidity with Extent of Lymphadenectomy for Primary Malignant Melanoma.

Renner P, Torzewski M, Zeman F, Babilas P, Kroemer A, Schlitt HJ, Dahlke MH.

Lymphat Res Biol. 2017 Jun;15(2):146-152. doi: 10.1089/lrb.2016.0018.

PMID:
28617648
6.

Selective p38α MAP kinase/MAPK14 inhibition in enzymatically modified LDL-stimulated human monocytes: implications for atherosclerosis.

Cheng F, Twardowski L, Fehr S, Aner C, Schaeffeler E, Joos T, Knorpp T, Dorweiler B, Laufer S, Schwab M, Torzewski M.

FASEB J. 2017 Feb;31(2):674-686. doi: 10.1096/fj.201600669R. Epub 2016 Nov 8.

PMID:
27871059
7.

Combined B, T and NK Cell Deficiency Accelerates Atherosclerosis in BALB/c Mice.

Cheng F, Twardowski L, Reifenberg K, Winter K, Canisius A, Pross E, Fan J, Schmitt E, Shultz LD, Lackner KJ, Torzewski M.

PLoS One. 2016 Aug 26;11(8):e0157311. doi: 10.1371/journal.pone.0157311. eCollection 2016.

8.

Enzymatically Modified Low-Density Lipoprotein Is Present in All Stages of Aortic Valve Sclerosis: Implications for Pathogenesis of the Disease.

Twardowski L, Cheng F, Michaelsen J, Winter S, Hofmann U, Schaeffeler E, Müller S, Sonnenberg M, Steuer K, Ott G, Schwab M, Franke UF, Torzewski M.

J Am Heart Assoc. 2015 Oct 16;4(10):e002156. doi: 10.1161/JAHA.115.002156.

9.

Malarial anemia: digestive vacuole of Plasmodium falciparum mediates complement deposition on bystander cells to provoke hemophagocytosis.

Dasari P, Fries A, Heber SD, Salama A, Blau IW, Lingelbach K, Bhakdi SC, Udomsangpetch R, Torzewski M, Reiss K, Bhakdi S.

Med Microbiol Immunol. 2014 Dec;203(6):383-93. doi: 10.1007/s00430-014-0347-0. Epub 2014 Jul 2.

PMID:
24985035
10.

C-reactive protein and arteriosclerosis.

Torzewski J, Fan J, Schunkert H, Szalai A, Torzewski M.

Mediators Inflamm. 2014;2014:646817. doi: 10.1155/2014/646817. Epub 2014 May 26. No abstract available.

11.

Animal models of C-reactive protein.

Torzewski M, Waqar AB, Fan J.

Mediators Inflamm. 2014;2014:683598. doi: 10.1155/2014/683598. Epub 2014 Apr 24. Review.

12.

T cell-specific overexpression of TGFß1 fails to influence atherosclerosis in ApoE-deficient mice.

Reifenberg K, Cheng F, Twardowski L, Küpper I, Wiese E, Bollmann F, Kleinert H, Blessing M, Lackner KJ, Torzewski M.

PLoS One. 2013 Dec 5;8(12):e81444. doi: 10.1371/journal.pone.0081444. eCollection 2013.

13.

Glutathione peroxidase-1 deficiency potentiates dysregulatory modifications of endothelial nitric oxide synthase and vascular dysfunction in aging.

Oelze M, Kröller-Schön S, Steven S, Lubos E, Doppler C, Hausding M, Tobias S, Brochhausen C, Li H, Torzewski M, Wenzel P, Bachschmid M, Lackner KJ, Schulz E, Münzel T, Daiber A.

Hypertension. 2014 Feb;63(2):390-6. doi: 10.1161/HYPERTENSIONAHA.113.01602. Epub 2013 Dec 2.

PMID:
24296279
14.

Impact of glutathione peroxidase-1 deficiency on macrophage foam cell formation and proliferation: implications for atherogenesis.

Cheng F, Torzewski M, Degreif A, Rossmann H, Canisius A, Lackner KJ.

PLoS One. 2013 Aug 22;8(8):e72063. doi: 10.1371/journal.pone.0072063. eCollection 2013.

15.

Complement and atherosclerosis-united to the point of no return?

Torzewski M, Bhakdi S.

Clin Biochem. 2013 Jan;46(1-2):20-5. doi: 10.1016/j.clinbiochem.2012.09.012. Epub 2012 Sep 23. Review.

PMID:
23010447
16.

Overexpression of TGF-ß1 in macrophages reduces and stabilizes atherosclerotic plaques in ApoE-deficient mice.

Reifenberg K, Cheng F, Orning C, Crain J, Küpper I, Wiese E, Protschka M, Blessing M, Lackner KJ, Torzewski M.

PLoS One. 2012;7(7):e40990. doi: 10.1371/journal.pone.0040990. Epub 2012 Jul 19.

17.

Digestive vacuole of Plasmodium falciparum released during erythrocyte rupture dually activates complement and coagulation.

Dasari P, Heber SD, Beisele M, Torzewski M, Reifenberg K, Orning C, Fries A, Zapf AL, Baumeister S, Lingelbach K, Udomsangpetch R, Bhakdi SC, Reiss K, Bhakdi S.

Blood. 2012 May 3;119(18):4301-10. doi: 10.1182/blood-2011-11-392134. Epub 2012 Mar 8.

PMID:
22403252
18.

Chronic inflammatory cardiomyopathy of interferon γ-overexpressing transgenic mice is mediated by tumor necrosis factor-α.

Torzewski M, Wenzel P, Kleinert H, Becker C, El-Masri J, Wiese E, Brandt M, Pautz A, Twardowski L, Schmitt E, Münzel T, Reifenberg K.

Am J Pathol. 2012 Jan;180(1):73-81. doi: 10.1016/j.ajpath.2011.09.006. Epub 2011 Nov 1.

PMID:
22051774
19.

Human oxidation-specific antibodies reduce foam cell formation and atherosclerosis progression.

Tsimikas S, Miyanohara A, Hartvigsen K, Merki E, Shaw PX, Chou MY, Pattison J, Torzewski M, Sollors J, Friedmann T, Lai NC, Hammond HK, Getz GS, Reardon CA, Li AC, Banka CL, Witztum JL.

J Am Coll Cardiol. 2011 Oct 11;58(16):1715-27. doi: 10.1016/j.jacc.2011.07.017.

20.

Differential effects of heart rate reduction with ivabradine in two models of endothelial dysfunction and oxidative stress.

Kröller-Schön S, Schulz E, Wenzel P, Kleschyov AL, Hortmann M, Torzewski M, Oelze M, Renné T, Daiber A, Münzel T.

Basic Res Cardiol. 2011 Nov;106(6):1147-58. doi: 10.1007/s00395-011-0227-3. Epub 2011 Oct 2.

PMID:
21964558
21.

Diagnostic accuracy of C-reactive protein and white blood cell counts in the early detection of inflammatory complications after open resection of colorectal cancer: a retrospective study of 1,187 patients.

Warschkow R, Tarantino I, Torzewski M, Näf F, Lange J, Steffen T.

Int J Colorectal Dis. 2011 Nov;26(11):1405-13. doi: 10.1007/s00384-011-1262-0. Epub 2011 Jun 24.

PMID:
21701807
22.

Cytogenetic analysis of a malignant triton tumour by comparative genomic hybridization (CGH) and review of the literature.

Koutsimpelas D, Brieger J, Heinrich U, Torzewski M, Sommer C, Mann WJ.

Eur Arch Otorhinolaryngol. 2011 Sep;268(9):1391-6. doi: 10.1007/s00405-011-1658-z. Epub 2011 Jun 5. Review.

PMID:
21643932
23.

Resveratrol reverses endothelial nitric-oxide synthase uncoupling in apolipoprotein E knockout mice.

Xia N, Daiber A, Habermeier A, Closs EI, Thum T, Spanier G, Lu Q, Oelze M, Torzewski M, Lackner KJ, Münzel T, Förstermann U, Li H.

J Pharmacol Exp Ther. 2010 Oct;335(1):149-54. doi: 10.1124/jpet.110.168724. Epub 2010 Jul 7.

PMID:
20610621
24.

Eosinophilic meningitis due to Angiostrongylus cantonensis in Germany.

Luessi F, Sollors J, Torzewski M, Müller HD, Siegel E, Blum J, Sommer C, Vogt T, Thömke F.

J Travel Med. 2009 Jul-Aug;16(4):292-4. doi: 10.1111/j.1708-8305.2009.00337.x.

25.

Lovastatin attenuates ionizing radiation-induced normal tissue damage in vivo.

Ostrau C, Hülsenbeck J, Herzog M, Schad A, Torzewski M, Lackner KJ, Fritz G.

Radiother Oncol. 2009 Sep;92(3):492-9. doi: 10.1016/j.radonc.2009.06.020. Epub 2009 Jul 15.

PMID:
19615773
26.

Nitrate tolerance as a model of vascular dysfunction: roles for mitochondrial aldehyde dehydrogenase and mitochondrial oxidative stress.

Daiber A, Oelze M, Wenzel P, Wickramanayake JM, Schuhmacher S, Jansen T, Lackner KJ, Torzewski M, Münzel T.

Pharmacol Rep. 2009 Jan-Feb;61(1):33-48. Review.

27.

Investigation of Sudan IV staining areas in aortas of infants and children: possible prelesional stages of atherogenesis.

Torzewski M, Navarro B, Cheng F, Canisius A, Schmidt T, Bhakdi S, Urban R, Lackner KJ.

Atherosclerosis. 2009 Sep;206(1):159-67. doi: 10.1016/j.atherosclerosis.2009.01.038. Epub 2009 Feb 7.

PMID:
19268943
28.

Endotoxin accelerates atherosclerosis independent of complement activation.

Reifenberg K, Lehr HA, Fan J, Koike T, Wiese E, Küpper I, Sagban TA, Schaefer SC, Zähringer U, Torzewski M, Lackner KJ, Bhakdi S.

Thromb Res. 2009 Feb;123(4):653-8. doi: 10.1016/j.thromres.2008.06.017. Epub 2008 Aug 9. No abstract available.

PMID:
18692867
29.

Potential protective role of apoprotein J (clusterin) in atherogenesis: binding to enzymatically modified low-density lipoprotein reduces fatty acid-mediated cytotoxicity.

Schwarz M, Spath L, Lux CA, Paprotka K, Torzewski M, Dersch K, Koch-Brandt C, Husmann M, Bhakdi S.

Thromb Haemost. 2008 Jul;100(1):110-8. doi: 10.1160/TH07-12-0737.

PMID:
18612545
30.

Subendothelial infiltration of neutrophil granulocytes and liberation of matrix-destabilizing enzymes in an experimental model of human neo-intima.

Dorweiler B, Torzewski M, Dahm M, Kirkpatrick CJ, Lackner KJ, Vahl CF.

Thromb Haemost. 2008 Feb;99(2):373-81. doi: 10.1160/TH07-06-0387.

PMID:
18278188
31.

No effect of C-reactive protein on early atherosclerosis in LDLR-/- / human C-reactive protein transgenic mice.

Torzewski M, Reifenberg K, Cheng F, Wiese E, Küpper I, Crain J, Lackner KJ, Bhakdi S.

Thromb Haemost. 2008 Jan;99(1):196-201. doi: 10.1160/TH07-10-0595.

PMID:
18217154
32.

Interferon-gamma induces chronic active myocarditis and cardiomyopathy in transgenic mice.

Reifenberg K, Lehr HA, Torzewski M, Steige G, Wiese E, Küpper I, Becker C, Ott S, Nusser P, Yamamura K, Rechtsteiner G, Warger T, Pautz A, Kleinert H, Schmidt A, Pieske B, Wenzel P, Münzel T, Löhler J.

Am J Pathol. 2007 Aug;171(2):463-72. Epub 2007 Jun 7.

33.

Glutathione peroxidase-1 activity, atherosclerotic burden, and cardiovascular prognosis.

Espinola-Klein C, Rupprecht HJ, Bickel C, Schnabel R, Genth-Zotz S, Torzewski M, Lackner K, Munzel T, Blankenberg S; AtheroGene Investigators.

Am J Cardiol. 2007 Mar 15;99(6):808-12. Epub 2007 Jan 30.

PMID:
17350371
34.

Deficiency of glutathione peroxidase-1 accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice.

Torzewski M, Ochsenhirt V, Kleschyov AL, Oelze M, Daiber A, Li H, Rossmann H, Tsimikas S, Reifenberg K, Cheng F, Lehr HA, Blankenberg S, Förstermann U, Münzel T, Lackner KJ.

Arterioscler Thromb Vasc Biol. 2007 Apr;27(4):850-7. Epub 2007 Jan 25.

PMID:
17255533
35.

Initiation and progression of atherosclerosis--enzymatic or oxidative modification of low-density lipoprotein?

Torzewski M, Lackner KJ.

Clin Chem Lab Med. 2006;44(12):1389-94. Review.

PMID:
17163812
36.

Increased plasma oxidized phospholipid:apolipoprotein B-100 ratio with concomitant depletion of oxidized phospholipids from atherosclerotic lesions after dietary lipid-lowering: a potential biomarker of early atherosclerosis regression.

Tsimikas S, Aikawa M, Miller FJ Jr, Miller ER, Torzewski M, Lentz SR, Bergmark C, Heistad DD, Libby P, Witztum JL.

Arterioscler Thromb Vasc Biol. 2007 Jan;27(1):175-81. Epub 2006 Nov 2.

PMID:
17082490
37.

Early diagnosis of Acanthamoeba infection during routine cytological examination of cerebrospinal fluid.

Petry F, Torzewski M, Bohl J, Wilhelm-Schwenkmezger T, Scheid P, Walochnik J, Michel R, Zöller L, Werhahn KJ, Bhakdi S, Lackner KJ.

J Clin Microbiol. 2006 May;44(5):1903-4.

38.

A novel in vitro model for the study of plaque development in atherosclerosis.

Dorweiler B, Torzewski M, Dahm M, Ochsenhirt V, Lehr HA, Lackner KJ, Vahl CF.

Thromb Haemost. 2006 Jan;95(1):182-9.

PMID:
16543978
39.

Serum starvation and growth factor receptor expression in vascular smooth muscle cells.

Zimmermann O, Zwaka TP, Marx N, Torzewski M, Bucher A, Guilliard P, Hannekum A, Hombach V, Torzewski J.

J Vasc Res. 2006;43(2):157-65. Epub 2006 Jan 11.

PMID:
16407661
40.

Role of C-reactive protein in atherogenesis: can the apolipoprotein E knockout mouse provide the answer?

Reifenberg K, Lehr HA, Baskal D, Wiese E, Schaefer SC, Black S, Samols D, Torzewski M, Lackner KJ, Husmann M, Blettner M, Bhakdi S.

Arterioscler Thromb Vasc Biol. 2005 Aug;25(8):1641-6. Epub 2005 May 26.

PMID:
15920030
41.

Glutathione peroxidase-1 and homocysteine for cardiovascular risk prediction: results from the AtheroGene study.

Schnabel R, Lackner KJ, Rupprecht HJ, Espinola-Klein C, Torzewski M, Lubos E, Bickel C, Cambien F, Tiret L, Münzel T, Blankenberg S.

J Am Coll Cardiol. 2005 May 17;45(10):1631-7. Epub 2005 Apr 25.

42.

Reduced in vivo aortic uptake of radiolabeled oxidation-specific antibodies reflects changes in plaque composition consistent with plaque stabilization.

Torzewski M, Shaw PX, Han KR, Shortal B, Lackner KJ, Witztum JL, Palinski W, Tsimikas S.

Arterioscler Thromb Vasc Biol. 2004 Dec;24(12):2307-12. Epub 2004 Nov 4.

PMID:
15528482
43.

Enzymatic modification of low-density lipoprotein in the arterial wall: a new role for plasmin and matrix metalloproteinases in atherogenesis.

Torzewski M, Suriyaphol P, Paprotka K, Spath L, Ochsenhirt V, Schmitt A, Han SR, Husmann M, Gerl VB, Bhakdi S, Lackner KJ.

Arterioscler Thromb Vasc Biol. 2004 Nov;24(11):2130-6. Epub 2004 Sep 2.

PMID:
15345515
44.

Beyond cholesterol: the enigma of atherosclerosis revisited.

Bhakdi S, Lackner KJ, Han SR, Torzewski M, Husmann M.

Thromb Haemost. 2004 Apr;91(4):639-45. Review.

PMID:
15045123
45.

Possible protective role for C-reactive protein in atherogenesis: complement activation by modified lipoproteins halts before detrimental terminal sequence.

Bhakdi S, Torzewski M, Paprotka K, Schmitt S, Barsoom H, Suriyaphol P, Han SR, Lackner KJ, Husmann M.

Circulation. 2004 Apr 20;109(15):1870-6. Epub 2004 Mar 22.

PMID:
15037531
46.

Glutathione peroxidase 1 activity and cardiovascular events in patients with coronary artery disease.

Blankenberg S, Rupprecht HJ, Bickel C, Torzewski M, Hafner G, Tiret L, Smieja M, Cambien F, Meyer J, Lackner KJ; AtheroGene Investigators.

N Engl J Med. 2003 Oct 23;349(17):1605-13.

47.

Enzymatically modified LDL induces cathepsin H in human monocytes: potential relevance in early atherogenesis.

Han SR, Momeni A, Strach K, Suriyaphol P, Fenske D, Paprotka K, Hashimoto SI, Torzewski M, Bhakdi S, Husmann M.

Arterioscler Thromb Vasc Biol. 2003 Apr 1;23(4):661-7. Epub 2003 Feb 27.

PMID:
12615673
48.

C-reactive protein binds to both oxidized LDL and apoptotic cells through recognition of a common ligand: Phosphorylcholine of oxidized phospholipids.

Chang MK, Binder CJ, Torzewski M, Witztum JL.

Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):13043-8. Epub 2002 Sep 20.

49.

Intracerebral hemorrhages, fibrinolysis, and prostate carcinoma.

Braun JS, Novak R, Torzewski M, Soehngen D.

J Neurol. 2002 Apr;249(4):478-9. No abstract available.

PMID:
11967657
50.

Enzymatically degraded LDL preferentially binds to CD14(high) CD16(+) monocytes and induces foam cell formation mediated only in part by the class B scavenger-receptor CD36.

Kapinsky M, Torzewski M, Büchler C, Duong CQ, Rothe G, Schmitz G.

Arterioscler Thromb Vasc Biol. 2001 Jun;21(6):1004-10.

PMID:
11397711

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