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Items: 1 to 50 of 87

1.

Posterior Reversible Encephalopathy Syndrome in late postpartum eclampsia.

Pezzi M, Le Piane E, Giglio AM, Pagnotta L, Scozzafava A, Tortorella V, Sergi A, Verre M.

Clin Ter. 2015;166(2):68-71. doi: 10.7417/CT.2015.1818.

PMID:
25945433
2.

Histamine poisoning from ingestion of fish or scombroid syndrome.

Tortorella V, Masciari P, Pezzi M, Mola A, Tiburzi SP, Zinzi MC, Scozzafava A, Verre M.

Case Rep Emerg Med. 2014;2014:482531. doi: 10.1155/2014/482531. Epub 2014 Dec 7.

3.

High serum resistin in chronic viral hepatitis is not a marker of metabolic disorder.

Morace C, Spadaro A, Cucunato M, Tortorella V, Consolo P, Luigiano C, Stabile G, Bonfiglio C, Bellerone R, Fortiguerra A, Alibrandi A, Crinò S, Carducci A, Resta ML, Ferraù O, Freni MA.

Hepatogastroenterology. 2010 Sep-Oct;57(102-103):1215-9.

PMID:
21410061
4.

Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents.

Catalano A, Carocci A, Corbo F, Franchini C, Muraglia M, Scilimati A, De Bellis M, De Luca A, Camerino DC, Sinicropi MS, Tortorella V.

Eur J Med Chem. 2008 Nov;43(11):2535-40. doi: 10.1016/j.ejmech.2008.01.023. Epub 2008 Jan 31.

PMID:
18342401
5.

High circulating D-dimers are associated with ascites and hepatocellular carcinoma in liver cirrhosis.

Spadaro A, Tortorella V, Morace C, Fortiguerra A, Composto P, Bonfiglio C, Alibrandi A, Luigiano C, De Caro G, Ajello A, Ferrau O, Freni MA.

World J Gastroenterol. 2008 Mar 14;14(10):1549-52.

6.

Prognostic factors of survival in complicated viral and alcoholic cirrhosis without hepatocellular carcinoma. A retrospective study.

Spadaro A, Luigiano C, De Caro G, Morace C, Tortorella V, Bonfiglio C, Pagano N, Consolo P, Alibrandi A, Ajello A, Ferraù O, Freni MA.

Minerva Gastroenterol Dietol. 2007 Dec;53(4):311-9.

PMID:
18043549
7.

Serotonin syndrome caused by olanzapine and clomipramine.

Verre M, Bossio F, Mammone A, Piccirillo M, Tancioni F, Tortorella V, Varano M.

Minerva Anestesiol. 2008 Jan-Feb;74(1-2):41-5. Epub 2007 Nov 16.

8.

AT1 receptor ligands: virtual-screening-based design with TOPP descriptors, synthesis, and biological evaluation of pyrrolidine derivatives.

Lamanna C, Catalano A, Carocci A, Di Mola A, Franchini C, Tortorella V, Vanderheyden PM, Sinicropi MS, Watson KA, Sciabola S.

ChemMedChem. 2007 Sep;2(9):1298-310.

PMID:
17628868
9.

Synthesis and biological evaluation of chiral alpha-aminoanilides with central antinociceptive activity.

Corbo F, Franchini C, Lentini G, Muraglia M, Ghelardini C, Matucci R, Galeotti N, Vivoli E, Tortorella V.

J Med Chem. 2007 Apr 19;50(8):1907-15. Epub 2007 Mar 21.

PMID:
17373780
10.

A new benzoxazine compound blocks KATP channels in pancreatic beta cells: molecular basis for tissue selectivity in vitro and hypoglycaemic action in vivo.

Rolland JF, Tricarico D, Laghezza A, Loiodice F, Tortorella V, Camerino DC.

Br J Pharmacol. 2006 Dec;149(7):870-9. Epub 2006 Oct 23.

11.

Evaluation of the pharmacological activity of the major mexiletine metabolites on skeletal muscle sodium currents.

De Bellis M, De Luca A, Rana F, Cavalluzzi MM, Catalano A, Lentini G, Franchini C, Tortorella V, Conte Camerino D.

Br J Pharmacol. 2006 Oct;149(3):300-10. Epub 2006 Aug 21.

12.

Facile, alternative route to lubeluzole, its enantiomer, and the racemate.

Bruno C, Carocci A, Catalano A, Cavalluzzi MM, Corbo F, Franchini C, Lentini G, Tortorella V.

Chirality. 2006 May 5;18(4):227-31.

PMID:
16521088
13.

Distribution of sigma receptors in EMT-6 cells: preliminary biological evaluation of PB167 and potential for in-vivo PET.

Colabufo NA, Berardi F, Contino M, Fazio F, Matarrese M, Moresco RM, Niso M, Perrone R, Tortorella V.

J Pharm Pharmacol. 2005 Nov;57(11):1453-9.

PMID:
16259778
14.

Design and synthesis of long-chain arylpiperazines with mixed affinity for serotonin transporter (SERT) and 5-HT(1A) receptor.

Perrone R, Berardi F, Colabufo NA, Lacivita E, Larizza C, Leopoldo M, Tortorella V.

J Pharm Pharmacol. 2005 Oct;57(10):1319-27.

PMID:
16259761
15.

Activation and inhibition of kidney CLC-K chloride channels by fenamates.

Liantonio A, Picollo A, Babini E, Carbonara G, Fracchiolla G, Loiodice F, Tortorella V, Pusch M, Camerino DC.

Mol Pharmacol. 2006 Jan;69(1):165-73. Epub 2005 Oct 21.

16.

Synthesis, biological evaluation, and molecular modeling investigation of new chiral fibrates with PPARalpha and PPARgamma agonist activity.

Pinelli A, Godio C, Laghezza A, Mitro N, Fracchiolla G, Tortorella V, Lavecchia A, Novellino E, Fruchart JC, Staels B, Crestani M, Loiodice F.

J Med Chem. 2005 Aug 25;48(17):5509-19.

PMID:
16107150
17.

Synthesis and biological evaluation of new clofibrate analogues as potential PPARalpha agonists.

Perrone MG, Santandrea E, Dell'Uomo N, Giannessi F, Milazzo FM, Sciarroni AF, Scilimati A, Tortorella V.

Eur J Med Chem. 2005 Feb;40(2):143-54.

PMID:
15694649
18.

Structure-affinity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinealkylamides, a new class of 5-hydroxytryptamine7 receptor agents.

Leopoldo M, Berardi F, Colabufo NA, Contino M, Lacivita E, Niso M, Perrone R, Tortorella V.

J Med Chem. 2004 Dec 16;47(26):6616-24.

PMID:
15588097
19.

Antiproliferative and cytotoxic effects of some sigma2 agonists and sigma1 antagonists in tumour cell lines.

Colabufo NA, Berardi F, Contino M, Niso M, Abate C, Perrone R, Tortorella V.

Naunyn Schmiedebergs Arch Pharmacol. 2004 Aug;370(2):106-13. Epub 2004 Jul 31.

PMID:
15322732
20.

New potent mexiletine and tocainide analogues evaluated in vivo and in vitro as antimyotonic agents on the myotonic ADR mouse.

De Luca A, Pierno S, Liantonio A, Desaphy JF, Natuzzi F, Didonna MP, Ferrannini E, Jockusch H, Franchini C, Lentini G, Corbo F, Tortorella V, Camerino DC.

Neuromuscul Disord. 2004 Jul;14(7):405-16.

PMID:
15210163
21.

4-(tetralin-1-yl)- and 4-(naphthalen-1-yl)alkyl derivatives of 1-cyclohexylpiperazine as sigma receptor ligands with agonist sigma2 activity.

Berardi F, Ferorelli S, Abate C, Colabufo NA, Contino M, Perrone R, Tortorella V.

J Med Chem. 2004 Apr 22;47(9):2308-17.

PMID:
15084129
22.

Studies on 1-arylpiperazine derivatives with affinity for rat 5-HT7 and 5-HT1A receptors.

Leopoldo M, Berardi F, Colabufo NA, Contino M, Lacivita E, Perrone R, Tortorella V.

J Pharm Pharmacol. 2004 Feb;56(2):247-55.

PMID:
15005884
23.

Stereospecific synthesis of "para-hydroxymexiletine" and sodium channel blocking activity evaluation.

Catalano A, Carocci A, Fracchiolla G, Franchini C, Lentini G, Tortorella V, De Luca A, De Bellis M, Desaphy JF, Conte Camerino D.

Chirality. 2004 Feb;16(2):72-8. Erratum in: Chirality. 2005 May 15;17(5):297.

PMID:
14712469
24.

Optimal requirements for high affinity and use-dependent block of skeletal muscle sodium channel by N-benzyl analogs of tocainide-like compounds.

De Luca A, Talon S, De Bellis M, Desaphy JF, Lentini G, Corbo F, Scilimati A, Franchini C, Tortorella V, Camerino DC.

Mol Pharmacol. 2003 Oct;64(4):932-45.

25.

A new method for evaluating sigma(2) ligand activity in the isolated guinea-pig bladder.

Colabufo NA, Berardi F, Contino M, Perrone R, Tortorella V.

Naunyn Schmiedebergs Arch Pharmacol. 2003 Aug;368(2):106-12. Epub 2003 Jul 17.

PMID:
12879208
26.

Synthesis of chiral 1-[omega-(4-chlorophenoxy)alkyl]-4-methylpiperidines and their biological evaluation at sigma1, sigma2, and sterol delta8-delta7 isomerase sites.

Berardi F, Loiodice F, Fracchiolla G, Colabufo NA, Perrone R, Tortorella V.

J Med Chem. 2003 May 22;46(11):2117-24.

PMID:
12747784
27.

[Pharmacological sympathetic block in complex regional pain syndrome].

Verre M, De Santis F, Glyronakis S, Grande AM, Renzi A, Santangelo E, Tortorella V, Varano M.

Clin Ter. 2002 Nov-Dec;153(6):367-72. Italian.

PMID:
12645391
28.

Inhibition of skeletal muscle sodium currents by mexiletine analogues: specific hydrophobic interactions rather than lipophilia per se account for drug therapeutic profile.

De Luca A, Talon S, De Bellis M, Desaphy JF, Franchini C, Lentini G, Catalano A, Corbo F, Tortorella V, Conte-Camerino D.

Naunyn Schmiedebergs Arch Pharmacol. 2003 Mar;367(3):318-27. Epub 2003 Jan 25.

PMID:
12644906
29.

Synthesis and structure-affinity relationships of 1-[omega-(4-aryl-1-piperazinyl)alkyl]-1-aryl ketones as 5-HT(7) receptor ligands.

Perrone R, Berardi F, Colabufo NA, Lacivita E, Leopoldo M, Tortorella V.

J Med Chem. 2003 Feb 13;46(4):646-9.

PMID:
12570387
30.

Structure-affinity relationship study on N-[4-(4-arylpiperazin-1-yl)butyl]arylcarboxamides as potent and selective dopamine D(3) receptor ligands.

Leopoldo M, Berardi F, Colabufo NA, De Giorgio P, Lacivita E, Perrone R, Tortorella V.

J Med Chem. 2002 Dec 19;45(26):5727-35.

PMID:
12477356
31.
32.

Determination of dopamine D(4) receptor density in rat striatum using PB12 as a probe.

Colabufo NA, Berardi F, Calò R, Leopoldo M, Perrone R, Tortorella V.

Eur J Pharmacol. 2001 Sep 7;427(1):1-5.

PMID:
11553357
35.

Different behavior toward racemization in basic media from chiral analogs of clofibric acid, the active metabolite of the antilipidemic drug clofibrate.

Ferorelli S, Loiodice F, Longo A, Molfetta A, Tortorella V, Amoroso R.

Chirality. 2000 Nov;12(10):697-704.

PMID:
11054827
36.

Synthesis of new 2,6-prolylxylidide analogues of tocainide as stereoselective blockers of voltage-gated Na(+) channels with increased potency and improved use-dependent activity.

Franchini C, Corbo F, Lentini G, Bruno G, Scilimati A, Tortorella V, Conte Camerino D, De Luca A.

J Med Chem. 2000 Oct 5;43(20):3792-8.

PMID:
11020295
37.

Pharmacological characterization of chloride channels belonging to the ClC family by the use of chiral clofibric acid derivatives.

Pusch M, Liantonio A, Bertorello L, Accardi A, De Luca A, Pierno S, Tortorella V, Camerino DC.

Mol Pharmacol. 2000 Sep;58(3):498-507.

39.

Homologation of mexiletine alkyl chain and stereoselective blockade of skeletal muscle sodium channels.

Duranti A, Franchini C, Lentini G, Loiodice F, Tortorella V, De Luca A, Pierno S, Conte Camerino D.

Eur J Med Chem. 2000 Jan;35(1):147-56.

PMID:
10733611
40.

Facile entry to (-)-(R)- and (+)-(S)-mexiletine.

Carocci A, Franchini C, Lentini G, Loiodice F, Tortorella V.

Chirality. 2000 Mar;12(3):103-6.

PMID:
10689287
41.
42.

Molecular determinants of mexiletine structure for potent and use-dependent block of skeletal muscle sodium channels.

De Luca A, Natuzzi F, Desaphy JF, Loni G, Lentini G, Franchini C, Tortorella V, Camerino DC.

Mol Pharmacol. 2000 Feb;57(2):268-77.

43.

Increased hindrance on the chiral carbon atom of mexiletine enhances the block of rat skeletal muscle Na+ channels in a model of myotonia induced by ATX.

Desaphy JF, Conte Camerino D, Franchini C, Lentini G, Tortorella V, De Luca A.

Br J Pharmacol. 1999 Nov;128(6):1165-74.

44.
46.

Effects of mexiletine on ATP sensitive K+ channel of rat skeletal muscle fibres: a state dependent mechanism of action.

Tricarico D, Barbieri M, Franchini C, Tortorella V, Camerino DC.

Br J Pharmacol. 1998 Oct;125(4):858-64.

47.

N-[2-[4-(4-Chlorophenyl)piperazin-1-yl]ethyl]-3-methoxybenzamide: a potent and selective dopamine D4 ligand.

Perrone R, Berardi F, Colabufo NA, Leopoldo M, Tortorella V.

J Med Chem. 1998 Nov 19;41(24):4903-9.

PMID:
9822559
48.

N-[omega-(Tetralin-1-yl)alkyl] derivatives of 3,3-dimethylpiperidine are highly potent and selective sigma1 or sigma2 ligands.

Berardi F, Santoro S, Perrone R, Tortorella V, Govoni S, Lucchi L.

J Med Chem. 1998 Oct 8;41(21):3940-7.

PMID:
9767631
49.

Inhibition of frog skeletal muscle sodium channels by newly synthesized chiral derivatives of mexiletine and tocainide.

De Luca A, Natuzzi F, Falcone G, Duranti A, Lentini G, Franchini C, Tortorella V, Camerino DC.

Naunyn Schmiedebergs Arch Pharmacol. 1997 Dec;356(6):777-87.

PMID:
9453464
50.

Evaluation of the antimyotonic activity of mexiletine and some new analogs on sodium currents of single muscle fibers and on the abnormal excitability of the myotonic ADR mouse.

De Luca A, Pierno S, Natuzzi F, Franchini C, Duranti A, Lentini G, Tortorella V, Jockusch H, Camerino DC.

J Pharmacol Exp Ther. 1997 Jul;282(1):93-100.

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