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Items: 1 to 50 of 127

1.

Measurement and implications of Saturn's gravity field and ring mass.

Iess L, Militzer B, Kaspi Y, Nicholson P, Durante D, Racioppa P, Anabtawi A, Galanti E, Hubbard W, Mariani MJ, Tortora P, Wahl S, Zannoni M.

Science. 2019 Jun 14;364(6445). pii: eaat2965. doi: 10.1126/science.aat2965. Epub 2019 Jan 17.

PMID:
30655447
2.

Methacycline displays a strong efficacy in reducing toxicity in a SCA3 Caenorhabditis elegans model.

Amigoni L, Airoldi C, Natalello A, Romeo M, Diomede L, Tortora P, Regonesi ME.

Biochim Biophys Acta Gen Subj. 2019 Feb;1863(2):279-290. doi: 10.1016/j.bbagen.2018.10.008. Epub 2018 Oct 27.

PMID:
30420336
3.

Targeting Amyloid Aggregation: An Overview of Strategies and Mechanisms.

Giorgetti S, Greco C, Tortora P, Aprile FA.

Int J Mol Sci. 2018 Sep 9;19(9). pii: E2677. doi: 10.3390/ijms19092677. Review.

4.

Protein Environment: A Crucial Triggering Factor in Josephin Domain Aggregation: The Role of 2,2,2-Trifluoroethanol.

Visentin C, Navarro S, Grasso G, Regonesi ME, Deriu MA, Tortora P, Ventura S.

Int J Mol Sci. 2018 Jul 24;19(8). pii: E2151. doi: 10.3390/ijms19082151.

5.

A fast and straightforward procedure for vault nanoparticle purification and the characterization of its endocytic uptake.

Galbiati E, Avvakumova S, La Rocca A, Pozzi M, Messali S, Magnaghi P, Colombo M, Prosperi D, Tortora P.

Biochim Biophys Acta Gen Subj. 2018 Oct;1862(10):2254-2260. doi: 10.1016/j.bbagen.2018.07.018. Epub 2018 Jul 20.

PMID:
30036602
6.

Measurement of Jupiter's asymmetric gravity field.

Iess L, Folkner WM, Durante D, Parisi M, Kaspi Y, Galanti E, Guillot T, Hubbard WB, Stevenson DJ, Anderson JD, Buccino DR, Casajus LG, Milani A, Park R, Racioppa P, Serra D, Tortora P, Zannoni M, Cao H, Helled R, Lunine JI, Miguel Y, Militzer B, Wahl S, Connerney JEP, Levin SM, Bolton SJ.

Nature. 2018 Mar 7;555(7695):220-222. doi: 10.1038/nature25776.

PMID:
29517001
7.

Publisher Correction: The polyglutamine protein ataxin-3 enables normal growth under heat shock conditions in the methylotrophic yeast Pichia pastoris.

Bonanomi M, Roffia V, De Palma A, Lombardi A, Aprile FA, Visentin C, Tortora P, Mauri P, Regonesi ME.

Sci Rep. 2018 Mar 6;8(1):4285. doi: 10.1038/s41598-018-22523-2.

8.

A High Sensitivity Biosensor to detect the presence of perfluorinated compounds in environment.

Cennamo N, Zeni L, Tortora P, Regonesi ME, Giusti A, Staiano M, D'Auria S, Varriale A.

Talanta. 2018 Feb 1;178:955-961. doi: 10.1016/j.talanta.2017.10.034. Epub 2017 Oct 21.

PMID:
29136923
9.

The polyglutamine protein ataxin-3 enables normal growth under heat shock conditions in the methylotrophic yeast Pichia pastoris.

Bonanomi M, Roffia V, De Palma A, Lombardi A, Aprile FA, Visentin C, Tortora P, Mauri P, Regonesi ME.

Sci Rep. 2017 Oct 17;7(1):13417. doi: 10.1038/s41598-017-13814-1. Erratum in: Sci Rep. 2018 Mar 6;8(1):4285.

10.

Epigallocatechin-3-gallate and related phenol compounds redirect the amyloidogenic aggregation pathway of ataxin-3 towards non-toxic aggregates and prevent toxicity in neural cells and Caenorhabditis elegans animal model.

Visentin C, Pellistri F, Natalello A, Vertemara J, Bonanomi M, Gatta E, Penco A, Relini A, De Gioia L, Airoldi C, Regonesi ME, Tortora P.

Hum Mol Genet. 2017 Sep 1;26(17):3271-3284. doi: 10.1093/hmg/ddx211.

PMID:
28633380
11.

Negatively charged silver nanoparticles with potent antibacterial activity and reduced toxicity for pharmaceutical preparations.

Salvioni L, Galbiati E, Collico V, Alessio G, Avvakumova S, Corsi F, Tortora P, Prosperi D, Colombo M.

Int J Nanomedicine. 2017 Mar 31;12:2517-2530. doi: 10.2147/IJN.S127799. eCollection 2017.

12.

Inhibition of α-Synuclein Fibril Elongation by Hsp70 Is Governed by a Kinetic Binding Competition between α-Synuclein Species.

Aprile FA, Arosio P, Fusco G, Chen SW, Kumita JR, Dhulesia A, Tortora P, Knowles TP, Vendruscolo M, Dobson CM, Cremades N.

Biochemistry. 2017 Mar 7;56(9):1177-1180. doi: 10.1021/acs.biochem.6b01178. Epub 2017 Feb 23.

PMID:
28230968
13.

How Epigallocatechin-3-gallate and Tetracycline Interact with the Josephin Domain of Ataxin-3 and Alter Its Aggregation Mode.

Bonanomi M, Visentin C, Natalello A, Spinelli M, Vanoni M, Airoldi C, Regonesi ME, Tortora P.

Chemistry. 2015 Dec 7;21(50):18383-93. doi: 10.1002/chem.201503086. Epub 2015 Nov 5.

PMID:
26538519
14.

The Toxic Effects of Pathogenic Ataxin-3 Variants in a Yeast Cellular Model.

Bonanomi M, Visentin C, Invernizzi G, Tortora P, Regonesi ME.

PLoS One. 2015 Jun 8;10(6):e0129727. doi: 10.1371/journal.pone.0129727. eCollection 2015.

15.

Peptide-nanoparticle ligation mediated by cutinase fusion for the development of cancer cell-targeted nanoconjugates.

Galbiati E, Cassani M, Verderio P, Martegani E, Colombo M, Tortora P, Mazzucchelli S, Prosperi D.

Bioconjug Chem. 2015 Apr 15;26(4):680-9. doi: 10.1021/acs.bioconjchem.5b00005. Epub 2015 Mar 13.

PMID:
25741889
16.

Protein nanocages for self-triggered nuclear delivery of DNA-targeted chemotherapeutics in Cancer Cells.

Bellini M, Mazzucchelli S, Galbiati E, Sommaruga S, Fiandra L, Truffi M, Rizzuto MA, Colombo M, Tortora P, Corsi F, Prosperi D.

J Control Release. 2014 Dec 28;196:184-96. doi: 10.1016/j.jconrel.2014.10.002. Epub 2014 Oct 13.

PMID:
25312541
17.

Immobilization of carboxypeptidase from Sulfolobus solfataricus on magnetic nanoparticles improves enzyme stability and functionality in organic media.

Sommaruga S, Galbiati E, Peñaranda-Avila J, Brambilla C, Tortora P, Colombo M, Prosperi D.

BMC Biotechnol. 2014 Sep 5;14:82. doi: 10.1186/1472-6750-14-82.

18.

Epigallocatechin-3-gallate and tetracycline differently affect ataxin-3 fibrillogenesis and reduce toxicity in spinocerebellar ataxia type 3 model.

Bonanomi M, Natalello A, Visentin C, Pastori V, Penco A, Cornelli G, Colombo G, Malabarba MG, Doglia SM, Relini A, Regonesi ME, Tortora P.

Hum Mol Genet. 2014 Dec 15;23(24):6542-52. doi: 10.1093/hmg/ddu373. Epub 2014 Jul 16.

PMID:
25030034
19.

The gravity field and interior structure of Enceladus.

Iess L, Stevenson DJ, Parisi M, Hemingway D, Jacobson RA, Lunine JI, Nimmo F, Armstrong JW, Asmar SW, Ducci M, Tortora P.

Science. 2014 Apr 4;344(6179):78-80. doi: 10.1126/science.1250551.

20.

Interactions of ataxin-3 with its molecular partners in the protein machinery that sorts protein aggregates to the aggresome.

Bonanomi M, Mazzucchelli S, D'Urzo A, Nardini M, Konarev PV, Invernizzi G, Svergun DI, Vanoni M, Regonesi ME, Tortora P.

Int J Biochem Cell Biol. 2014 Jun;51:58-64. doi: 10.1016/j.biocel.2014.03.015. Epub 2014 Mar 28.

PMID:
24685680
21.

Biotechnological approaches toward nanoparticle biofunctionalization.

Avvakumova S, Colombo M, Tortora P, Prosperi D.

Trends Biotechnol. 2014 Jan;32(1):11-20. doi: 10.1016/j.tibtech.2013.09.006. Epub 2013 Oct 30. Review.

PMID:
24182737
22.

Glucose-6-phosphate dehydrogenase deficiency in Italian blood donors: prevalence and molecular defect characterization.

Maffi D, Pasquino MT, Mandarino L, Tortora P, Girelli G, Meo D, Grazzini G, Caprari P.

Vox Sang. 2014 Apr;106(3):227-33. doi: 10.1111/vox.12096. Epub 2013 Oct 18.

PMID:
24134566
23.

A conserved loop in polynucleotide phosphorylase (PNPase) essential for both RNA and ADP/phosphate binding.

Carzaniga T, Mazzantini E, Nardini M, Regonesi ME, Greco C, Briani F, De Gioia L, Dehò G, Tortora P.

Biochimie. 2014 Feb;97:49-59. doi: 10.1016/j.biochi.2013.09.018. Epub 2013 Sep 26.

PMID:
24075876
24.

Different ataxin-3 amyloid aggregates induce intracellular Ca(2+) deregulation by different mechanisms in cerebellar granule cells.

Pellistri F, Bucciantini M, Invernizzi G, Gatta E, Penco A, Frana AM, Nosi D, Relini A, Regonesi ME, Gliozzi A, Tortora P, Robello M, Stefani M.

Biochim Biophys Acta. 2013 Dec;1833(12):3155-3165. doi: 10.1016/j.bbamcr.2013.08.019. Epub 2013 Sep 11.

25.

The conformational ensemble of the disordered and aggregation-protective 182-291 region of ataxin-3.

Invernizzi G, Lambrughi M, Regonesi ME, Tortora P, Papaleo E.

Biochim Biophys Acta. 2013 Nov;1830(11):5236-47. doi: 10.1016/j.bbagen.2013.07.007. Epub 2013 Jul 25.

PMID:
23891935
26.

Hsp70 oligomerization is mediated by an interaction between the interdomain linker and the substrate-binding domain.

Aprile FA, Dhulesia A, Stengel F, Roodveldt C, Benesch JL, Tortora P, Robinson CV, Salvatella X, Dobson CM, Cremades N.

PLoS One. 2013 Jun 28;8(6):e67961. doi: 10.1371/journal.pone.0067961. Print 2013.

27.

A hydrophobic gold surface triggers misfolding and aggregation of the amyloidogenic Josephin domain in monomeric form, while leaving the oligomers unaffected.

Apicella A, Soncini M, Deriu MA, Natalello A, Bonanomi M, Dellasega D, Tortora P, Regonesi ME, Casari CS.

PLoS One. 2013;8(3):e58794. doi: 10.1371/journal.pone.0058794. Epub 2013 Mar 19.

28.

Orientation-controlled conjugation of haloalkane dehalogenase fused homing peptides to multifunctional nanoparticles for the specific recognition of cancer cells.

Mazzucchelli S, Colombo M, Verderio P, Rozek E, Andreata F, Galbiati E, Tortora P, Corsi F, Prosperi D.

Angew Chem Int Ed Engl. 2013 Mar 11;52(11):3121-5. doi: 10.1002/anie.201209662. Epub 2013 Feb 5. No abstract available.

PMID:
23386453
29.

The relationship between aggregation and toxicity of polyglutamine-containing ataxin-3 in the intracellular environment of Escherichia coli.

Invernizzi G, Aprile FA, Natalello A, Ghisleni A, Penco A, Relini A, Doglia SM, Tortora P, Regonesi ME.

PLoS One. 2012;7(12):e51890. doi: 10.1371/journal.pone.0051890. Epub 2012 Dec 14.

30.

The tides of Titan.

Iess L, Jacobson RA, Ducci M, Stevenson DJ, Lunine JI, Armstrong JW, Asmar SW, Racioppa P, Rappaport NJ, Tortora P.

Science. 2012 Jul 27;337(6093):457-9. doi: 10.1126/science.1219631. Epub 2012 Jun 28.

31.

Temperature profoundly affects ataxin-3 fibrillogenesis.

Apicella A, Natalello A, Frana AM, Baserga A, Casari CS, Bottani CE, Doglia SM, Tortora P, Regonesi ME.

Biochimie. 2012 Apr;94(4):1026-31. doi: 10.1016/j.biochi.2012.01.002. Epub 2012 Jan 9.

PMID:
22234302
32.

The role of the central flexible region on the aggregation and conformational properties of human ataxin-3.

Santambrogio C, Frana AM, Natalello A, Papaleo E, Regonesi ME, Doglia SM, Tortora P, Invernizzi G, Grandori R.

FEBS J. 2012 Feb;279(3):451-63. doi: 10.1111/j.1742-4658.2011.08438.x. Epub 2012 Jan 9.

33.

Site-specific conjugation of ScFvs antibodies to nanoparticles by bioorthogonal strain-promoted alkyne-nitrone cycloaddition.

Colombo M, Sommaruga S, Mazzucchelli S, Polito L, Verderio P, Galeffi P, Corsi F, Tortora P, Prosperi D.

Angew Chem Int Ed Engl. 2012 Jan 9;51(2):496-9. doi: 10.1002/anie.201106775. Epub 2011 Nov 25.

PMID:
22121095
34.

Multiple presentation of Scfv800E6 on silica nanospheres enhances targeting efficiency toward HER-2 receptor in breast cancer cells.

Mazzucchelli S, Verderio P, Sommaruga S, Colombo M, Salvadè A, Corsi F, Galeffi P, Tortora P, Prosperi D.

Bioconjug Chem. 2011 Nov 16;22(11):2296-303. doi: 10.1021/bc200352x. Epub 2011 Oct 31.

PMID:
22010849
35.

Highly efficient production of anti-HER2 scFv antibody variant for targeting breast cancer cells.

Sommaruga S, Lombardi A, Salvadè A, Mazzucchelli S, Corsi F, Galeffi P, Tortora P, Prosperi D.

Appl Microbiol Biotechnol. 2011 Aug;91(3):613-21. doi: 10.1007/s00253-011-3306-3. Epub 2011 May 3.

PMID:
21538107
36.

A major role for side-chain polyglutamine hydrogen bonding in irreversible ataxin-3 aggregation.

Natalello A, Frana AM, Relini A, Apicella A, Invernizzi G, Casari C, Gliozzi A, Doglia SM, Tortora P, Regonesi ME.

PLoS One. 2011 Apr 13;6(4):e18789. doi: 10.1371/journal.pone.0018789.

37.

Uniform lipopolysaccharide (LPS)-loaded magnetic nanoparticles for the investigation of LPS-TLR4 signaling.

Piazza M, Colombo M, Zanoni I, Granucci F, Tortora P, Weiss J, Gioannini T, Prosperi D, Peri F.

Angew Chem Int Ed Engl. 2011 Jan 17;50(3):622-6. doi: 10.1002/anie.201004655. Epub 2010 Nov 9. No abstract available.

38.

Site-specific mutation of Staphylococcus aureus VraS reveals a crucial role for the VraR-VraS sensor in the emergence of glycopeptide resistance.

Galbusera E, Renzoni A, Andrey DO, Monod A, Barras C, Tortora P, Polissi A, Kelley WL.

Antimicrob Agents Chemother. 2011 Mar;55(3):1008-20. doi: 10.1128/AAC.00720-10. Epub 2010 Dec 20.

39.

The mechanism of the polynucleotide phosphorylase-catalyzed arsenolysis of ADP.

Németi B, Regonesi ME, Tortora P, Gregus Z.

Biochimie. 2011 Mar;93(3):624-7. doi: 10.1016/j.biochi.2010.11.013. Epub 2010 Dec 3.

PMID:
21130834
40.

Investigating the structural biofunctionality of antibodies conjugated to magnetic nanoparticles.

Occhipinti E, Verderio P, Natalello A, Galbiati E, Colombo M, Mazzucchelli S, Salvadè A, Tortora P, Doglia SM, Prosperi D.

Nanoscale. 2011 Feb;3(2):387-90. doi: 10.1039/c0nr00436g. Epub 2010 Sep 29.

PMID:
20877896
41.

Single-domain protein A-engineered magnetic nanoparticles: toward a universal strategy to site-specific labeling of antibodies for targeted detection of tumor cells.

Mazzucchelli S, Colombo M, De Palma C, Salvadè A, Verderio P, Coghi MD, Clementi E, Tortora P, Corsi F, Prosperi D.

ACS Nano. 2010 Oct 26;4(10):5693-702. doi: 10.1021/nn101307r.

PMID:
20825223
42.

Polynucleotide phosphorylase and mitochondrial ATP synthase mediate reduction of arsenate to the more toxic arsenite by forming arsenylated analogues of ADP and ATP.

Németi B, Regonesi ME, Tortora P, Gregus Z.

Toxicol Sci. 2010 Oct;117(2):270-81. doi: 10.1093/toxsci/kfq141. Epub 2010 May 10.

PMID:
20457661
43.

Gravity field, shape, and moment of inertia of Titan.

Iess L, Rappaport NJ, Jacobson RA, Racioppa P, Stevenson DJ, Tortora P, Armstrong JW, Asmar SW.

Science. 2010 Mar 12;327(5971):1367-9. doi: 10.1126/science.1182583.

44.

Proteomic and biochemical analyses unveil tight interaction of ataxin-3 with tubulin.

Mazzucchelli S, De Palma A, Riva M, D'Urzo A, Pozzi C, Pastori V, Comelli F, Fusi P, Vanoni M, Tortora P, Mauri P, Regonesi ME.

Int J Biochem Cell Biol. 2009 Dec;41(12):2485-92. doi: 10.1016/j.biocel.2009.08.003. Epub 2009 Aug 8.

PMID:
19666135
45.

Structure prediction and functional analysis of KdsD, an enzyme involved in lipopolysaccharide biosynthesis.

Sommaruga S, Gioia LD, Tortora P, Polissi A.

Biochem Biophys Res Commun. 2009 Oct 16;388(2):222-7. doi: 10.1016/j.bbrc.2009.07.154. Epub 2009 Aug 5.

PMID:
19664604
46.

Randomised study for the 1-year crestal bone maintenance around modified diameter implants with different loading protocols: a radiographic evaluation.

Danza M, Tortora P, Quaranta A, Perrotti V, Vozza I, Piattelli A.

Clin Oral Investig. 2010 Aug;14(4):417-26. doi: 10.1007/s00784-009-0314-0. Epub 2009 Jul 15.

PMID:
19603200
47.

Interaction of selected divalent metal ions with human ataxin-3 Q36.

Stawoska I, Wesełucha-Birczyńska A, Regonesi ME, Riva M, Tortora P, Stochel G.

J Biol Inorg Chem. 2009 Nov;14(8):1175-85. doi: 10.1007/s00775-009-0561-1. Epub 2009 Jul 4.

PMID:
19575245
48.

Regulation of Escherichia coli polynucleotide phosphorylase by ATP.

Del Favero M, Mazzantini E, Briani F, Zangrossi S, Tortora P, Dehò G.

J Biol Chem. 2008 Oct 10;283(41):27355-9. doi: 10.1074/jbc.C800113200. Epub 2008 Jul 23.

49.

A combined approach of mass spectrometry, molecular modeling, and site-directed mutagenesis highlights key structural features responsible for the thermostability of Sulfolobus solfataricus carboxypeptidase.

Sommaruga S, De Palma A, Mauri PL, Trisciani M, Basilico F, Martelli PL, Casadio R, Tortora P, Occhipinti E.

Proteins. 2008 Jun;71(4):1843-52. doi: 10.1002/prot.21868.

PMID:
18175312
50.

Hyperion's sponge-like appearance.

Thomas PC, Armstrong JW, Asmar SW, Burns JA, Denk T, Giese B, Helfenstein P, Iess L, Johnson TV, McEwen A, Nicolaisen L, Porco C, Rappaport N, Richardson J, Somenzi L, Tortora P, Turtle EP, Veverka J.

Nature. 2007 Jul 5;448(7149):50-3.

PMID:
17611535

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