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Items: 25


CD11b activation suppresses TLR-dependent inflammation and autoimmunity in systemic lupus erythematosus.

Faridi MH, Khan SQ, Zhao W, Lee HW, Altintas MM, Zhang K, Kumar V, Armstrong AR, Carmona-Rivera C, Dorschner JM, Schnaith AM, Li X, Ghodke-Puranik Y, Moore E, Purmalek M, Irizarry-Caro J, Zhang T, Day R, Stoub D, Hoffmann V, Khaliqdina SJ, Bhargava P, Santander AM, Torroella-Kouri M, Issac B, Cimbaluk DJ, Zloza A, Prabhakar R, Deep S, Jolly M, Koh KH, Reichner JS, Bradshaw EM, Chen J, Moita LF, Yuen PS, Li Tsai W, Singh B, Reiser J, Nath SK, Niewold TB, Vazquez-Padron RI, Kaplan MJ, Gupta V.

J Clin Invest. 2017 Apr 3;127(4):1271-1283. doi: 10.1172/JCI88442. Epub 2017 Mar 6.


Breast cancers from black women exhibit higher numbers of immunosuppressive macrophages with proliferative activity and of crown-like structures associated with lower survival compared to non-black Latinas and Caucasians.

Koru-Sengul T, Santander AM, Miao F, Sanchez LG, Jorda M, Glück S, Ince TA, Nadji M, Chen Z, Penichet ML, Cleary MP, Torroella-Kouri M.

Breast Cancer Res Treat. 2016 Jul;158(1):113-126. doi: 10.1007/s10549-016-3847-3. Epub 2016 Jun 9.


Paracrine Interactions between Adipocytes and Tumor Cells Recruit and Modify Macrophages to the Mammary Tumor Microenvironment: The Role of Obesity and Inflammation in Breast Adipose Tissue.

Santander AM, Lopez-Ocejo O, Casas O, Agostini T, Sanchez L, Lamas-Basulto E, Carrio R, Cleary MP, Gonzalez-Perez RR, Torroella-Kouri M.

Cancers (Basel). 2015 Jan 15;7(1):143-78. doi: 10.3390/cancers7010143.


Phospholipid makeup of the breast adipose tissue is impacted by obesity and mammary cancer in the mouse: Results of a pilot study.

Margolis M, Perez O Jr, Martinez M, Santander AM, Mendez AJ, Nadji M, Nayer A, Bhattacharya S, Torroella-Kouri M.

Biochimie. 2015 Jan;108:133-9. doi: 10.1016/j.biochi.2014.11.009. Epub 2014 Nov 18.


Alterations in macrophages and monocytes from tumor-bearing mice: evidence of local and systemic immune impairment.

Torroella-Kouri M, Rodríguez D, Caso R.

Immunol Res. 2013 Dec;57(1-3):86-98. doi: 10.1007/s12026-013-8438-3. Review.


Obesity induced a leptin-Notch signaling axis in breast cancer.

Battle M, Gillespie C, Quarshie A, Lanier V, Harmon T, Wilson K, Torroella-Kouri M, Gonzalez-Perez RR.

Int J Cancer. 2014 Apr 1;134(7):1605-16. doi: 10.1002/ijc.28496. Epub 2013 Oct 8.


Tumor microenvironment profoundly modifies functional status of macrophages: peritoneal and tumor-associated macrophages are two very different subpopulations.

Rodríguez D, Silvera R, Carrio R, Nadji M, Caso R, Rodríguez G, Iragavarapu-Charyulu V, Torroella-Kouri M.

Cell Immunol. 2013 May-Jun;283(1-2):51-60. doi: 10.1016/j.cellimm.2013.06.008. Epub 2013 Jun 19.


Macrophages as independent prognostic factors in small T1 breast cancers.

Carrio R, Koru-Sengul T, Miao F, Glück S, Lopez O, Selman Y, Alvarez C, Milikowski C, Gomez C, Jorda M, Nadji M, Torroella-Kouri M.

Oncol Rep. 2013 Jan;29(1):141-8. doi: 10.3892/or.2012.2088. Epub 2012 Oct 17.


Oncogenic role and therapeutic target of leptin signaling in breast cancer and cancer stem cells.

Guo S, Liu M, Wang G, Torroella-Kouri M, Gonzalez-Perez RR.

Biochim Biophys Acta. 2012 Apr;1825(2):207-22. doi: 10.1016/j.bbcan.2012.01.002. Epub 2012 Jan 24. Review.


Decreased accumulation of immune regulatory cells is correlated to the antitumor effect of IFN-γ overexpression in the tumor.

Carrio R, Torroella-Kouri M, Libreros S, García-Areas RA, Iragavarapu-Charyulu V, López DM.

Int J Oncol. 2011 Dec;39(6):1619-27. doi: 10.3892/ijo.2011.1169. Epub 2011 Aug 18.


Induction of proinflammatory mediators by CHI3L1 is reduced by chitin treatment: decreased tumor metastasis in a breast cancer model.

Libreros S, Garcia-Areas R, Shibata Y, Carrio R, Torroella-Kouri M, Iragavarapu-Charyulu V.

Int J Cancer. 2012 Jul 15;131(2):377-86. doi: 10.1002/ijc.26379. Epub 2011 Oct 20.


Expression of the inflammatory chemokines CCL2, CCL5 and CXCL2 and the receptors CCR1-3 and CXCR2 in T lymphocytes from mammary tumor-bearing mice.

Owen JL, Criscitiello MF, Libreros S, Garcia-Areas R, Guthrie K, Torroella-Kouri M, Iragavarapu-Charyulu V.

Cell Immunol. 2011;270(2):172-82. doi: 10.1016/j.cellimm.2011.05.004. Epub 2011 May 10.


Tumor-induced thymic atrophy: alteration in interferons and Jak/Stats signaling pathways.

Carrio R, Torroella-Kouri M, Iragavarapu-Charyulu V, Lopez DM.

Int J Oncol. 2011 Feb;38(2):547-53. doi: 10.3892/ijo.2010.870. Epub 2010 Dec 14.


Blood monocytes from mammary tumor-bearing mice: early targets of tumor-induced immune suppression?

Caso R, Silvera R, Carrio R, Iragavarapu-Charyulu V, Gonzalez-Perez RR, Torroella-Kouri M.

Int J Oncol. 2010 Oct;37(4):891-900.


Role of the proteasome in the downregulation of transcription factors NFkappaB and C/EBP in macrophages from tumor hosts.

Perry G, Iragavarapu-Charyulu V, Harhaj EW, Torroella-Kouri M.

Oncol Rep. 2010 Mar;23(3):875-81.


Identification of a subpopulation of macrophages in mammary tumor-bearing mice that are neither M1 nor M2 and are less differentiated.

Torroella-Kouri M, Silvera R, Rodriguez D, Caso R, Shatry A, Opiela S, Ilkovitch D, Schwendener RA, Iragavarapu-Charyulu V, Cardentey Y, Strbo N, Lopez DM.

Cancer Res. 2009 Jun 1;69(11):4800-9. doi: 10.1158/0008-5472.CAN-08-3427. Epub 2009 May 19.


Molecular events involved in the increased expression of matrix metalloproteinase-9 by T lymphocytes of mammary tumor-bearing mice.

Owen JL, Torroella-Kouri M, Iragavarapu-Charyulu V.

Int J Mol Med. 2008 Jan;21(1):125-34.


GM-CSF up-regulates the expression of CCL2 by T lymphocytes in mammary tumor-bearing mice.

Owen JL, Torroella-Kouri M, Handel-Fernandez ME, Iragavarapu-Charyulu V.

Int J Mol Med. 2007 Jul;20(1):129-36.


The expression of CCL2 by T lymphocytes of mammary tumor bearers: role of tumor-derived factors.

Owen JL, Lopez DM, Grosso JF, Guthrie KM, Herbert LM, Torroella-Kouri M, Iragavarapu-Charyulu V.

Cell Immunol. 2005 Jun;235(2):122-35. Epub 2005 Oct 21.


Altered IL-12 Signaling Pathways Contribute to the Deficient IFN-γ Production by T Splenocytes from Tumor-bearing Mice.

Torroella-Kouri M, Herbert LM, Perry G, Lopez DM.

Cancer Genomics Proteomics. 2004 Sep-Dec;1(5-6):345-354. Epub 2004 Sep 1.


IL-11-induced reduction of C/EBP transcription factor binding may contribute to the IL-12 downregulation in tumor-bearing mice.

Torroella-Kouri M, Keith JC, Ivanova M, Lopez DM.

Int J Oncol. 2003 Feb;22(2):439-48.


HPV prevalence among Mexican women with neoplastic and normal cervixes.

Torroella-Kouri M, Morsberger S, Carrillo A, Mohar A, Meneses A, Ibarra M, Daniel RW, Ghaffari AM, Solorza G, Shah KV.

Gynecol Oncol. 1998 Jul;70(1):115-20.


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