Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 103

1.

Identification of biologic agents to neutralize the bicomponent leukocidins of Staphylococcus aureus.

Chan R, Buckley PT, O'Malley A, Sause WE, Alonzo F 3rd, Lubkin A, Boguslawski KM, Payne A, Fernandez J, Strohl WR, Whitaker B, Lynch AS, Torres VJ.

Sci Transl Med. 2019 Jan 16;11(475). pii: eaat0882. doi: 10.1126/scitranslmed.aat0882.

PMID:
30651319
2.

Sequential evolution of virulence and resistance during clonal spread of community-acquired methicillin-resistant Staphylococcus aureus.

Copin R, Sause WE, Fulmer Y, Balasubramanian D, Dyzenhaus S, Ahmed JM, Kumar K, Lees J, Stachel A, Fisher JC, Drlica K, Phillips M, Weiser JN, Planet PJ, Uhlemann AC, Altman DR, Sebra R, van Bakel H, Lighter J, Torres VJ, Shopsin B.

Proc Natl Acad Sci U S A. 2019 Jan 11. pii: 201814265. doi: 10.1073/pnas.1814265116. [Epub ahead of print]

PMID:
30635416
3.

Staphylococcus aureus Impairs the Function of and Kills Human Dendritic Cells via the LukAB Toxin.

Berends ETM, Zheng X, Zwack EE, Ménager MM, Cammer M, Shopsin B, Torres VJ.

MBio. 2019 Jan 2;10(1). pii: e01918-18. doi: 10.1128/mBio.01918-18.

4.

Hierarchy of human IgG recognition within the Staphylococcus aureus immunome.

Radke EE, Brown SM, Pelzek AJ, Fulmer Y, Hernandez DN, Torres VJ, Thomsen IP, Chiang WK, Miller AO, Shopsin B, Silverman GJ.

Sci Rep. 2018 Sep 5;8(1):13296. doi: 10.1038/s41598-018-31424-3.

5.

Genome Plasticity of agr-Defective Staphylococcus aureus during Clinical Infection.

Altman DR, Sullivan MJ, Chacko KI, Balasubramanian D, Pak TR, Sause WE, Kumar K, Sebra R, Deikus G, Attie O, Rose H, Lewis M, Fulmer Y, Bashir A, Kasarskis A, Schadt EE, Richardson AR, Torres VJ, Shopsin B, van Bakel H.

Infect Immun. 2018 Sep 21;86(10). pii: e00331-18. doi: 10.1128/IAI.00331-18. Print 2018 Oct.

6.

Staphylococcus aureus biofilms release leukocidins to elicit extracellular trap formation and evade neutrophil-mediated killing.

Bhattacharya M, Berends ETM, Chan R, Schwab E, Roy S, Sen CK, Torres VJ, Wozniak DJ.

Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):7416-7421. doi: 10.1073/pnas.1721949115. Epub 2018 Jun 25.

7.

Genomic and Geographic Context for the Evolution of High-Risk Carbapenem-Resistant Enterobacter cloacae Complex Clones ST171 and ST78.

Gomez-Simmonds A, Annavajhala MK, Wang Z, Macesic N, Hu Y, Giddins MJ, O'Malley A, Toussaint NC, Whittier S, Torres VJ, Uhlemann AC.

MBio. 2018 May 29;9(3). pii: e00542-18. doi: 10.1128/mBio.00542-18.

8.

Serologic Detection of Antibodies Targeting the Leukocidin LukAB Strongly Predicts Staphylococcus aureus in Children With Invasive Infection.

Wood JB, Jones LS, Soper NR, Xu M, Torres VJ, Buddy Creech C, Thomsen IP.

J Pediatric Infect Dis Soc. 2018 Mar 10. doi: 10.1093/jpids/piy017. [Epub ahead of print]

PMID:
29538707
9.

Human Memory B Cells Targeting Staphylococcus aureus Exotoxins Are Prevalent with Skin and Soft Tissue Infection.

Pelzek AJ, Shopsin B, Radke EE, Tam K, Ueberheide BM, Fenyö D, Brown SM, Li Q, Rubin A, Fulmer Y, Chiang WK, Hernandez DN, El Bannoudi H, Sause WE, Sommerfield A, Thomsen IP, Miller AO, Torres VJ, Silverman GJ.

MBio. 2018 Mar 13;9(2). pii: e02125-17. doi: 10.1128/mBio.02125-17.

10.

Nutritional Regulation of the Sae Two-Component System by CodY in Staphylococcus aureus.

Mlynek KD, Sause WE, Moormeier DE, Sadykov MR, Hill KR, Torres VJ, Bayles KW, Brinsmade SR.

J Bacteriol. 2018 Mar 26;200(8). pii: e00012-18. doi: 10.1128/JB.00012-18. Print 2018 Apr 15.

11.

Staphylococcus aureus Responds to the Central Metabolite Pyruvate To Regulate Virulence.

Harper L, Balasubramanian D, Ohneck EA, Sause WE, Chapman J, Mejia-Sosa B, Lhakhang T, Heguy A, Tsirigos A, Ueberheide B, Boyd JM, Lun DS, Torres VJ.

MBio. 2018 Jan 23;9(1). pii: e02272-17. doi: 10.1128/mBio.02272-17.

12.

Staphylococcus aureus produces pain through pore-forming toxins and neuronal TRPV1 that is silenced by QX-314.

Blake KJ, Baral P, Voisin T, Lubkin A, Pinho-Ribeiro FA, Adams KL, Roberson DP, Ma YC, Otto M, Woolf CJ, Torres VJ, Chiu IM.

Nat Commun. 2018 Jan 2;9(1):37. doi: 10.1038/s41467-017-02448-6.

13.

Roles of Staphylococcus aureus Mnh1 and Mnh2 Antiporters in Salt Tolerance, Alkali Tolerance, and Pathogenesis.

Vaish M, Price-Whelan A, Reyes-Robles T, Liu J, Jereen A, Christie S, Alonzo F 3rd, Benson MA, Torres VJ, Krulwich TA.

J Bacteriol. 2018 Feb 7;200(5). pii: e00611-17. doi: 10.1128/JB.00611-17. Print 2018 Mar 1.

14.

After the deluge: mining Staphylococcus aureus genomic data for clinical associations and host-pathogen interactions.

Copin R, Shopsin B, Torres VJ.

Curr Opin Microbiol. 2018 Feb;41:43-50. doi: 10.1016/j.mib.2017.11.014. Epub 2017 Dec 19. Review.

PMID:
29197673
15.

Note from a Concerned American Citizen, an Infection and Immunity and mBio Editor, and a Scientist with Puerto Rican Roots.

Torres VJ.

Infect Immun. 2017 Nov 17;85(12). pii: e00702-17. doi: 10.1128/IAI.00702-17. Print 2017 Dec. No abstract available.

16.

Dietary Manganese Promotes Staphylococcal Infection of the Heart.

Juttukonda LJ, Berends ETM, Zackular JP, Moore JL, Stier MT, Zhang Y, Schmitz JE, Beavers WN, Wijers CD, Gilston BA, Kehl-Fie TE, Atkinson J, Washington MK, Peebles RS, Chazin WJ, Torres VJ, Caprioli RM, Skaar EP.

Cell Host Microbe. 2017 Oct 11;22(4):531-542.e8. doi: 10.1016/j.chom.2017.08.009. Epub 2017 Sep 21.

17.

Staphylococcus aureus strain Newman D2C contains mutations in major regulatory pathways that cripple its pathogenesis.

Sause WE, Copin R, O'malley A, Chan R, Morrow BJ, Buckley PT, Fernandez J, Lynch AS, Shopsin B, Torres VJ.

J Bacteriol. 2017 Sep 18. pii: JB.00476-17. doi: 10.1128/JB.00476-17. [Epub ahead of print]

18.

The Staphylococcus aureus superantigen SElX is a bifunctional toxin that inhibits neutrophil function.

Tuffs SW, James DBA, Bestebroer J, Richards AC, Goncheva MI, O'Shea M, Wee BA, Seo KS, Schlievert PM, Lengeling A, van Strijp JA, Torres VJ, Fitzgerald JR.

PLoS Pathog. 2017 Sep 7;13(9):e1006461. doi: 10.1371/journal.ppat.1006461. eCollection 2017 Sep.

19.

Epidermal Growth Factor Receptor Signaling Enhances the Proinflammatory Effects of Staphylococcus aureus Gamma-Toxin on the Mucosa.

Gillman AN, Breshears LM, Kistler CK, Finnegan PM, Torres VJ, Schlievert PM, Peterson ML.

Toxins (Basel). 2017 Jun 28;9(7). pii: E202. doi: 10.3390/toxins9070202.

20.

Leukocidins: staphylococcal bi-component pore-forming toxins find their receptors.

Spaan AN, van Strijp JAG, Torres VJ.

Nat Rev Microbiol. 2017 Jul;15(7):435-447. doi: 10.1038/nrmicro.2017.27. Epub 2017 Apr 19. Review.

21.

The Suf Iron-Sulfur Cluster Biosynthetic System Is Essential in Staphylococcus aureus, and Decreased Suf Function Results in Global Metabolic Defects and Reduced Survival in Human Neutrophils.

Roberts CA, Al-Tameemi HM, Mashruwala AA, Rosario-Cruz Z, Chauhan U, Sause WE, Torres VJ, Belden WJ, Boyd JM.

Infect Immun. 2017 May 23;85(6). pii: e00100-17. doi: 10.1128/IAI.00100-17. Print 2017 Jun.

22.

Using Quantitative Spectrometry to Understand the Influence of Genetics and Nutritional Perturbations On the Virulence Potential of Staphylococcus aureus.

Chapman JR, Balasubramanian D, Tam K, Askenazi M, Copin R, Shopsin B, Torres VJ, Ueberheide BM.

Mol Cell Proteomics. 2017 Apr;16(4 suppl 1):S15-S28. doi: 10.1074/mcp.O116.065581. Epub 2017 Feb 14.

23.

Monoclonal Antibodies Against the Staphylococcus aureus Bicomponent Leukotoxin AB Isolated Following Invasive Human Infection Reveal Diverse Binding and Modes of Action.

Thomsen IP, Sapparapu G, James DBA, Cassat JE, Nagarsheth M, Kose N, Putnam N, Boguslawski KM, Jones LS, Wood JB, Creech CB, Torres VJ, Crowe JE Jr.

J Infect Dis. 2017 Apr 1;215(7):1124-1131. doi: 10.1093/infdis/jix071.

24.

Staphylococcus aureus pathogenesis in diverse host environments.

Balasubramanian D, Harper L, Shopsin B, Torres VJ.

Pathog Dis. 2017 Jan 1;75(1). doi: 10.1093/femspd/ftx005. Review.

25.

Bacteria and endothelial cells: a toxic relationship.

Lubkin A, Torres VJ.

Curr Opin Microbiol. 2017 Feb;35:58-63. doi: 10.1016/j.mib.2016.11.008. Epub 2016 Dec 22. Review.

26.

A first-principles model of copper-boron interactions in Si: implications for the light-induced degradation of solar Si.

Wright E, Coutinho J, Öberg S, Torres VJ.

J Phys Condens Matter. 2017 Feb 15;29(6):065701. doi: 10.1088/1361-648X/aa4d78. Epub 2016 Dec 19.

PMID:
27991421
27.

Staphylococcus aureus Leukocidin LukED and HIV-1 gp120 Target Different Sequence Determinants on CCR5.

Tam K, Schultz M, Reyes-Robles T, Vanwalscappel B, Horton J, Alonzo F 3rd, Wu B, Landau NR, Torres VJ.

MBio. 2016 Dec 13;7(6). pii: e02024-16. doi: 10.1128/mBio.02024-16.

28.

Staphylococcus aureus Pore-Forming Toxins.

Reyes-Robles T, Torres VJ.

Curr Top Microbiol Immunol. 2017;409:121-144. doi: 10.1007/82_2016_16.

PMID:
27406190
29.

Staphylococcus aureus Coordinates Leukocidin Expression and Pathogenesis by Sensing Metabolic Fluxes via RpiRc.

Balasubramanian D, Ohneck EA, Chapman J, Weiss A, Kim MK, Reyes-Robles T, Zhong J, Shaw LN, Lun DS, Ueberheide B, Shopsin B, Torres VJ.

MBio. 2016 Jun 21;7(3). pii: e00818-16. doi: 10.1128/mBio.00818-16.

30.

Exploiting dominant-negative toxins to combat Staphylococcus aureus pathogenesis.

Reyes-Robles T, Lubkin A, Alonzo F 3rd, Lacy DB, Torres VJ.

EMBO Rep. 2016 May;17(5):780. doi: 10.15252/embr.201670010. No abstract available.

31.

The Endurance of Microbiology: An Interview with Mike Jetten, Mark Martin, Ute Römling, and Victor Torres.

Jetten MSM, Martin MO, Römling U, Torres VJ.

Trends Microbiol. 2016 May;24(5):319-323. doi: 10.1016/j.tim.2016.02.020. No abstract available.

PMID:
27102958
32.

Exploiting dominant-negative toxins to combat Staphylococcus aureus pathogenesis.

Reyes-Robles T, Lubkin A, Alonzo F 3rd, Lacy DB, Torres VJ.

EMBO Rep. 2016 Mar;17(3):428-40. doi: 10.15252/embr.201540994. Epub 2016 Feb 8. Erratum in: EMBO Rep. 2016 May;17(5):780.

33.

Host response to Staphylococcus aureus cytotoxins in children with cystic fibrosis.

Chadha AD, Thomsen IP, Jimenez-Truque N, Soper NR, Jones LS, Sokolow AG, Torres VJ, Creech CB.

J Cyst Fibros. 2016 Sep;15(5):597-604. doi: 10.1016/j.jcf.2015.12.023. Epub 2016 Jan 25.

34.

Antibody-Based Biologics and Their Promise to Combat Staphylococcus aureus Infections.

Sause WE, Buckley PT, Strohl WR, Lynch AS, Torres VJ.

Trends Pharmacol Sci. 2016 Mar;37(3):231-241. doi: 10.1016/j.tips.2015.11.008. Epub 2015 Dec 22. Review.

35.

The ever-emerging complexity of α-toxin's interaction with host cells.

Lubkin A, Torres VJ.

Proc Natl Acad Sci U S A. 2015 Nov 17;112(46):14123-4. doi: 10.1073/pnas.1519766112. Epub 2015 Nov 5. No abstract available.

36.

The Relationship between Glycan Binding and Direct Membrane Interactions in Vibrio cholerae Cytolysin, a Channel-forming Toxin.

De S, Bubnys A, Alonzo F 3rd, Hyun J, Lary JW, Cole JL, Torres VJ, Olson R.

J Biol Chem. 2015 Nov 20;290(47):28402-15. doi: 10.1074/jbc.M115.675967. Epub 2015 Sep 28.

37.

Counter inhibition between leukotoxins attenuates Staphylococcus aureus virulence.

Yoong P, Torres VJ.

Nat Commun. 2015 Sep 2;6:8125. doi: 10.1038/ncomms9125.

38.

Staphylococcus aureus Targets the Duffy Antigen Receptor for Chemokines (DARC) to Lyse Erythrocytes.

Spaan AN, Reyes-Robles T, Badiou C, Cochet S, Boguslawski KM, Yoong P, Day CJ, de Haas CJ, van Kessel KP, Vandenesch F, Jennings MP, Le Van Kim C, Colin Y, van Strijp JA, Henry T, Torres VJ.

Cell Host Microbe. 2015 Sep 9;18(3):363-70. doi: 10.1016/j.chom.2015.08.001. Epub 2015 Aug 27.

39.

Staphylococcus aureus Biofilms Induce Macrophage Dysfunction Through Leukocidin AB and Alpha-Toxin.

Scherr TD, Hanke ML, Huang O, James DB, Horswill AR, Bayles KW, Fey PD, Torres VJ, Kielian T.

MBio. 2015 Aug 25;6(4). pii: e01021-15. doi: 10.1128/mBio.01021-15.

40.

Staphylococcus aureus Leukocidin A/B (LukAB) Kills Human Monocytes via Host NLRP3 and ASC when Extracellular, but Not Intracellular.

Melehani JH, James DB, DuMont AL, Torres VJ, Duncan JA.

PLoS Pathog. 2015 Jun 12;11(6):e1004970. doi: 10.1371/journal.ppat.1004970. eCollection 2015 Jun.

41.

Autophagy is a key tolerance mechanism during Staphylococcus aureus infection.

Maurer K, Torres VJ, Cadwell K.

Autophagy. 2015;11(7):1184-6. doi: 10.1080/15548627.2015.1058685.

42.

Elimination of HIV-1-Infected Primary T Cell Reservoirs in an In Vitro Model of Latency.

Rawlings SA, Alonzo F 3rd, Kozhaya L, Torres VJ, Unutmaz D.

PLoS One. 2015 May 19;10(5):e0126917. doi: 10.1371/journal.pone.0126917. eCollection 2015.

43.

Autophagy mediates tolerance to Staphylococcus aureus alpha-toxin.

Maurer K, Reyes-Robles T, Alonzo F 3rd, Durbin J, Torres VJ, Cadwell K.

Cell Host Microbe. 2015 Apr 8;17(4):429-40. doi: 10.1016/j.chom.2015.03.001. Epub 2015 Mar 26.

44.

Rot is a key regulator of Staphylococcus aureus biofilm formation.

Mootz JM, Benson MA, Heim CE, Crosby HA, Kavanaugh JS, Dunman PM, Kielian T, Torres VJ, Horswill AR.

Mol Microbiol. 2015 Apr;96(2):388-404. doi: 10.1111/mmi.12943. Epub 2015 Feb 26.

45.

The cholesterol-dependent cytolysins pneumolysin and streptolysin O require binding to red blood cell glycans for hemolytic activity.

Shewell LK, Harvey RM, Higgins MA, Day CJ, Hartley-Tassell LE, Chen AY, Gillen CM, James DB, Alonzo F 3rd, Torres VJ, Walker MJ, Paton AW, Paton JC, Jennings MP.

Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):E5312-20. doi: 10.1073/pnas.1412703111. Epub 2014 Nov 24.

46.

Nfu facilitates the maturation of iron-sulfur proteins and participates in virulence in Staphylococcus aureus.

Mashruwala AA, Pang YY, Rosario-Cruz Z, Chahal HK, Benson MA, Mike LA, Skaar EP, Torres VJ, Nauseef WM, Boyd JM.

Mol Microbiol. 2015 Feb;95(3):383-409. doi: 10.1111/mmi.12860. Epub 2014 Dec 20.

47.

Gastrointestinal dissemination and transmission of Staphylococcus aureus following bacteremia.

Kernbauer E, Maurer K, Torres VJ, Shopsin B, Cadwell K.

Infect Immun. 2015 Jan;83(1):372-8. doi: 10.1128/IAI.02272-14. Epub 2014 Nov 10.

48.

The staphylococcal toxins γ-haemolysin AB and CB differentially target phagocytes by employing specific chemokine receptors.

Spaan AN, Vrieling M, Wallet P, Badiou C, Reyes-Robles T, Ohneck EA, Benito Y, de Haas CJ, Day CJ, Jennings MP, Lina G, Vandenesch F, van Kessel KP, Torres VJ, van Strijp JA, Henry T.

Nat Commun. 2014 Nov 11;5:5438. doi: 10.1038/ncomms6438.

49.

Structure-based functional characterization of repressor of toxin (Rot), a central regulator of Staphylococcus aureus virulence.

Killikelly A, Benson MA, Ohneck EA, Sampson JM, Jakoncic J, Spurrier B, Torres VJ, Kong XP.

J Bacteriol. 2015 Jan 1;197(1):188-200. doi: 10.1128/JB.02317-14. Epub 2014 Oct 20.

50.

Cytotoxic Virulence Predicts Mortality in Nosocomial Pneumonia Due to Methicillin-Resistant Staphylococcus aureus.

Rose HR, Holzman RS, Altman DR, Smyth DS, Wasserman GA, Kafer JM, Wible M, Mendes RE, Torres VJ, Shopsin B.

J Infect Dis. 2015 Jun 15;211(12):1862-74. doi: 10.1093/infdis/jiu554. Epub 2014 Oct 7.

Supplemental Content

Loading ...
Support Center