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Items: 1 to 50 of 72

1.

Sequential ubiquitination of NLRP3 by RNF125 and Cbl-b limits inflammasome activation and endotoxemia.

Tang J, Tu S, Lin G, Guo H, Yan C, Liu Q, Huang L, Tang N, Xiao Y, Pope RM, Rajaram MVS, Amer AO, Ahmer BM, Gunn JS, Wozniak DJ, Tao L, Coppola V, Zhang L, Langdon WY, Torrelles JB, Lipkowitz S, Zhang J.

J Exp Med. 2020 Apr 6;217(4). pii: e20182091. doi: 10.1084/jem.20182091.

PMID:
31999304
2.

Underestimated Manipulative Roles of Mycobacterium tuberculosis Cell Envelope Glycolipids During Infection.

Garcia-Vilanova A, Chan J, Torrelles JB.

Front Immunol. 2019 Dec 18;10:2909. doi: 10.3389/fimmu.2019.02909. eCollection 2019. Review.

3.

Improved Alere Determine Lipoarabinomannan Antigen Detection Test for the Diagnosis of Human and Bovine Tuberculosis by Manipulating Urine and Milk.

García JI, Kelley HV, Meléndez J, de León RAA, Castillo A, Sidiki S, Yusoof KA, Nunes E, Téllez CL, Mejía-Villatoro CR, Ikeda J, García-Basteiro AL, Wang SH, Torrelles JB.

Sci Rep. 2019 Nov 29;9(1):18012. doi: 10.1038/s41598-019-54537-9.

4.

MDR/XDR-TB Colour Test for drug susceptibility testing of Mycobacterium tuberculosis, Northwest Ethiopia.

Shibabaw A, Gelaw B, Kelley HV, Tesfaye E, Balada-Llasat JM, Evans CA, Torrelles JB, Wang SH, Tessema B.

Int J Infect Dis. 2020 Jan;90:213-218. doi: 10.1016/j.ijid.2019.10.041. Epub 2019 Nov 2.

5.

Evaluation of Mycobacterium tuberculosis lipoarabinomannan antigen assay and rapid serology blood test for the diagnosis of bovine tuberculosis in Ethiopia.

Zewude A, Mohammed T, Terfassa L, Hunt WG, Pan X, Balada-Llasat JM, Gebreyes W, Torrelles JB, Wang SH, Ameni G.

BMC Vet Res. 2019 Oct 22;15(1):359. doi: 10.1186/s12917-019-2114-3.

6.

Identification of an Increased Alveolar Macrophage Subpopulation in Old Mice That Displays Unique Inflammatory Characteristics and Is Permissive to Mycobacterium tuberculosis Infection.

Lafuse WP, Rajaram MVS, Wu Q, Moliva JI, Torrelles JB, Turner J, Schlesinger LS.

J Immunol. 2019 Oct 15;203(8):2252-2264. doi: 10.4049/jimmunol.1900495. Epub 2019 Sep 11.

PMID:
31511357
7.

Evaluation of the tuberculosis culture color plate test for rapid detection of drug susceptible and drug-resistant Mycobacterium tuberculosis in a resource-limited setting, Addis Ababa, Ethiopia.

Mekonnen B, Mihret A, Getahun M, Hailu T, Sidiki S, V Kelley H, Scordo JM, Hunt WG, Pan X, Balada-Llasat JM, Gebreyes W, Evans CA, Aseffa A, Torrelles JB, Wang SH, Abebe T.

PLoS One. 2019 May 28;14(5):e0215679. doi: 10.1371/journal.pone.0215679. eCollection 2019.

8.

The Lung Mucosa Environment in the Elderly Increases Host Susceptibility to Mycobacterium tuberculosis Infection.

Moliva JI, Duncan MA, Olmo-Fontánez A, Akhter A, Arnett E, Scordo JM, Ault R, Sasindran SJ, Azad AK, Montoya MJ, Reinhold-Larsson N, Rajaram MVS, Merrit RE, Lafuse WP, Zhang L, Wang SH, Beamer G, Wang Y, Proud K, Maselli DJ, Peters J, Weintraub ST, Turner J, Schlesinger LS, Torrelles JB.

J Infect Dis. 2019 Jul 2;220(3):514-523. doi: 10.1093/infdis/jiz138.

PMID:
30923818
9.

The human lung mucosa drives differential Mycobacterium tuberculosis infection outcome in the alveolar epithelium.

Scordo JM, Olmo-Fontánez AM, Kelley HV, Sidiki S, Arcos J, Akhter A, Wewers MD, Torrelles JB.

Mucosal Immunol. 2019 May;12(3):795-804. doi: 10.1038/s41385-019-0156-2. Epub 2019 Mar 7.

10.

Selective delipidation of Mycobacterium bovis BCG enables direct pulmonary vaccination and enhances protection against Mycobacterium tuberculosis.

Moliva JI, Hossfeld AP, Sidiki S, Canan CH, Dwivedi V, Beamer G, Turner J, Torrelles JB.

Mucosal Immunol. 2019 May;12(3):805-815. doi: 10.1038/s41385-019-0148-2. Epub 2019 Feb 18.

11.

Accuracy of the color plate micro-colony detection for the diagnosis of Mycobacterium tuberculosis complex in Northwest Ethiopia.

Shibabaw A, Gelaw B, Kelley H, Balada-Llasat JM, Evans C, Wang SH, Torrelles JB, Tessema B.

Tuberculosis (Edinb). 2019 Jan;114:54-60. doi: 10.1016/j.tube.2018.11.007. Epub 2018 Nov 28.

PMID:
30711158
12.

Publisher Correction: Mycobacterium tuberculosis carrying a rifampicin drug resistance mutation reprograms macrophage metabolism through cell wall lipid changes.

Howard NC, Marin ND, Ahmed M, Rosa BA, Martin J, Bambouskova M, Sergushichev A, Loginicheva E, Kurepina N, Rangel-Moreno J, Chen L, Kreiswirth BN, Klein RS, Balada-Llasat JM, Torrelles JB, Amarasinghe GK, Mitreva M, Artyomov MN, Hsu FF, Mathema B, Khader SA.

Nat Microbiol. 2018 Nov;3(11):1327. doi: 10.1038/s41564-018-0281-9.

PMID:
30327492
13.

The UALE project: a cross-sectional approach for trends in HIV/STI prevalence among key populations attending STI clinics in Guatemala.

García JI, Sabidó M, Nikiforov M, Smith A, Hernández G, Ortiz R, Ardani L, Cajas A, Camey E, Torrelles JB, Wang SH, Campbell CNJ, Folch C, Casabona J; UALE Study Group.

BMJ Open. 2018 Sep 19;8(9):e022632. doi: 10.1136/bmjopen-2018-022632.

14.

Mycobacterium tuberculosis carrying a rifampicin drug resistance mutation reprograms macrophage metabolism through cell wall lipid changes.

Howard NC, Marin ND, Ahmed M, Rosa BA, Martin J, Bambouskova M, Sergushichev A, Loginicheva E, Kurepina N, Rangel-Moreno J, Chen L, Kreiswirth BN, Klein RS, Balada-Llasat JM, Torrelles JB, Amarasinghe GK, Mitreva M, Artyomov MN, Hsu FF, Mathema B, Khader SA.

Nat Microbiol. 2018 Oct;3(10):1099-1108. doi: 10.1038/s41564-018-0245-0. Epub 2018 Sep 17. Erratum in: Nat Microbiol. 2018 Nov;3(11):1327.

15.

CD38 Is Robustly Induced in Human Macrophages and Monocytes in Inflammatory Conditions.

Amici SA, Young NA, Narvaez-Miranda J, Jablonski KA, Arcos J, Rosas L, Papenfuss TL, Torrelles JB, Jarjour WN, Guerau-de-Arellano M.

Front Immunol. 2018 Jul 10;9:1593. doi: 10.3389/fimmu.2018.01593. eCollection 2018.

16.

Low-cost diagnostic test for susceptible and drug-resistant tuberculosis in rural Malawi.

Zhang A, Jumbe E, Krysiak R, Sidiki S, Kelley HV, Chemey EK, Kamba C, Mwapasa V, García JI, Norris A, Pan XJ, Evans C, Wang SH, Kwiek JJ, Torrelles JB.

Afr J Lab Med. 2018 Jun 4;7(1):690. doi: 10.4102/ajlm.v7i1.690. eCollection 2018.

17.

Mannose-capped lipoarabinomannan in Mycobacterium tuberculosis pathogenesis.

Turner J, Torrelles JB.

Pathog Dis. 2018 Jun 1;76(4). doi: 10.1093/femspd/fty026. Review.

18.

Checks and Balances between Autophagy and Inflammasomes during Infection.

Seveau S, Turner J, Gavrilin MA, Torrelles JB, Hall-Stoodley L, Yount JS, Amer AO.

J Mol Biol. 2018 Jan 19;430(2):174-192. doi: 10.1016/j.jmb.2017.11.006. Epub 2017 Nov 21. Review.

19.

Interleukin-17 limits hypoxia-inducible factor 1α and development of hypoxic granulomas during tuberculosis.

Domingo-Gonzalez R, Das S, Griffiths KL, Ahmed M, Bambouskova M, Gopal R, Gondi S, Muñoz-Torrico M, Salazar-Lezama MA, Cruz-Lagunas A, Jiménez-Álvarez L, Ramirez-Martinez G, Espinosa-Soto R, Sultana T, Lyons-Weiler J, Reinhart TA, Arcos J, de la Luz Garcia-Hernandez M, Mastrangelo MA, Al-Hammadi N, Townsend R, Balada-Llasat JM, Torrelles JB, Kaplan G, Horne W, Kolls JK, Artyomov MN, Rangel-Moreno J, Zúñiga J, Khader SA.

JCI Insight. 2017 Oct 5;2(19). pii: 92973. doi: 10.1172/jci.insight.92973.

20.

Cellular fatty acid synthase is required for late stages of HIV-1 replication.

Kulkarni MM, Ratcliff AN, Bhat M, Alwarawrah Y, Hughes P, Arcos J, Loiselle D, Torrelles JB, Funderburg NT, Haystead TA, Kwiek JJ.

Retrovirology. 2017 Sep 29;14(1):45. doi: 10.1186/s12977-017-0368-z.

21.

Exposure to human alveolar lining fluid enhances Mycobacterium bovis BCG vaccine efficacy against Mycobacterium tuberculosis infection in a CD8+ T-cell-dependent manner.

Moliva JI, Hossfeld AP, Canan CH, Dwivedi V, Wewers MD, Beamer G, Turner J, Torrelles JB.

Mucosal Immunol. 2018 May;11(3):968-978. doi: 10.1038/mi.2017.80. Epub 2017 Sep 20.

22.

Mycobacterium tuberculosis universal stress protein Rv2623 interacts with the putative ATP binding cassette (ABC) transporter Rv1747 to regulate mycobacterial growth.

Glass LN, Swapna G, Chavadi SS, Tufariello JM, Mi K, Drumm JE, Lam TT, Zhu G, Zhan C, Vilchéze C, Arcos J, Chen Y, Bi L, Mehta S, Porcelli SA, Almo SC, Yeh SR, Jacobs WR Jr, Torrelles JB, Chan J.

PLoS Pathog. 2017 Jul 28;13(7):e1006515. doi: 10.1371/journal.ppat.1006515. eCollection 2017 Jul.

23.

Modifications of Pseudomonas aeruginosa cell envelope in the cystic fibrosis airway alters interactions with immune cells.

Hill PJ, Scordo JM, Arcos J, Kirkby SE, Wewers MD, Wozniak DJ, Torrelles JB.

Sci Rep. 2017 Jul 6;7(1):4761. doi: 10.1038/s41598-017-05253-9.

24.

Immune Responses to Bacillus Calmette-Guérin Vaccination: Why Do They Fail to Protect against Mycobacterium tuberculosis?

Moliva JI, Turner J, Torrelles JB.

Front Immunol. 2017 Apr 5;8:407. doi: 10.3389/fimmu.2017.00407. eCollection 2017. Review.

25.

Mycobacterium tuberculosis Cell Wall Fragments Released upon Bacterial Contact with the Human Lung Mucosa Alter the Neutrophil Response to Infection.

Scordo JM, Arcos J, Kelley HV, Diangelo L, Sasindran SJ, Youngmin E, Wewers MD, Wang SH, Balada-Llasat JM, Torrelles JB.

Front Immunol. 2017 Mar 20;8:307. doi: 10.3389/fimmu.2017.00307. eCollection 2017.

26.

Integrating Lung Physiology, Immunology, and Tuberculosis.

Torrelles JB, Schlesinger LS.

Trends Microbiol. 2017 Aug;25(8):688-697. doi: 10.1016/j.tim.2017.03.007. Epub 2017 Mar 30. Review.

27.

Mycobacterium tuberculosis cell wall released fragments by the action of the human lung mucosa modulate macrophages to control infection in an IL-10-dependent manner.

Arcos J, Sasindran SJ, Moliva JI, Scordo JM, Sidiki S, Guo H, Venigalla P, Kelley HV, Lin G, Diangelo L, Silwani SN, Zhang J, Turner J, Torrelles JB.

Mucosal Immunol. 2017 Sep;10(5):1248-1258. doi: 10.1038/mi.2016.115. Epub 2016 Dec 21.

28.

Polyphosphate and associated enzymes as global regulators of stress response and virulence in Campylobacter jejuni.

Kumar A, Gangaiah D, Torrelles JB, Rajashekara G.

World J Gastroenterol. 2016 Sep 7;22(33):7402-14. doi: 10.3748/wjg.v22.i33.7402. Review.

29.

Entrapment of H1N1 Influenza Virus Derived Conserved Peptides in PLGA Nanoparticles Enhances T Cell Response and Vaccine Efficacy in Pigs.

Hiremath J, Kang KI, Xia M, Elaish M, Binjawadagi B, Ouyang K, Dhakal S, Arcos J, Torrelles JB, Jiang X, Lee CW, Renukaradhya GJ.

PLoS One. 2016 Apr 19;11(4):e0151922. doi: 10.1371/journal.pone.0151922. eCollection 2016.

30.

Development of a porcine reproductive and respiratory syndrome virus-like-particle-based vaccine and evaluation of its immunogenicity in pigs.

Binjawadagi B, Lakshmanappa YS, Longchao Z, Dhakal S, Hiremath J, Ouyang K, Shyu DL, Arcos J, Pengcheng S, Gilbertie A, Zuckermann F, Torrelles JB, Jackwood D, Fang Y, Renukaradhya GJ.

Arch Virol. 2016 Jun;161(6):1579-89. doi: 10.1007/s00705-016-2812-0. Epub 2016 Mar 23.

PMID:
27008569
31.

Comparative analysis of routes of immunization of a live porcine reproductive and respiratory syndrome virus (PRRSV) vaccine in a heterologous virus challenge study.

Ouyang K, Hiremath J, Binjawadagi B, Shyu DL, Dhakal S, Arcos J, Schleappi R, Holman L, Roof M, Torrelles JB, Renukaradhya GJ.

Vet Res. 2016 Mar 17;47:45. doi: 10.1186/s13567-016-0331-3.

32.

Polyphosphate kinases modulate Campylobacter jejuni outer membrane constituents and alter its capacity to invade and survive in intestinal epithelial cells in vitro.

Pina-Mimbela R, Madrid JA, Kumar A, Torrelles JB, Rajashekara G.

Emerg Microbes Infect. 2015 Dec 30;4(12):e77. doi: 10.1038/emi.2015.77.

33.

Alveolar Epithelial Cells in Mycobacterium tuberculosis Infection: Active Players or Innocent Bystanders?

Scordo JM, Knoell DL, Torrelles JB.

J Innate Immun. 2016;8(1):3-14. doi: 10.1159/000439275. Epub 2015 Sep 18. Review.

34.

Prospects in Mycobacterium bovis Bacille Calmette et Guérin (BCG) vaccine diversity and delivery: why does BCG fail to protect against tuberculosis?

Moliva JI, Turner J, Torrelles JB.

Vaccine. 2015 Sep 22;33(39):5035-41. doi: 10.1016/j.vaccine.2015.08.033. Epub 2015 Aug 28. Review.

35.

Lung Mucosa Lining Fluid Modification of Mycobacterium tuberculosis to Reprogram Human Neutrophil Killing Mechanisms.

Arcos J, Diangelo LE, Scordo JM, Sasindran SJ, Moliva JI, Turner J, Torrelles JB.

J Infect Dis. 2015 Sep 15;212(6):948-58. doi: 10.1093/infdis/jiv146. Epub 2015 Mar 6.

36.

Characterization of lung inflammation and its impact on macrophage function in aging.

Canan CH, Gokhale NS, Carruthers B, Lafuse WP, Schlesinger LS, Torrelles JB, Turner J.

J Leukoc Biol. 2014 Sep;96(3):473-80. doi: 10.1189/jlb.4A0214-093RR. Epub 2014 Jun 16.

37.

An innovative approach to induce cross-protective immunity against porcine reproductive and respiratory syndrome virus in the lungs of pigs through adjuvanted nanotechnology-based vaccination.

Binjawadagi B, Dwivedi V, Manickam C, Ouyang K, Torrelles JB, Renukaradhya GJ.

Int J Nanomedicine. 2014 Mar 24;9:1519-35. doi: 10.2147/IJN.S59924. eCollection 2014.

38.

Molecular composition of the alveolar lining fluid in the aging lung.

Moliva JI, Rajaram MV, Sidiki S, Sasindran SJ, Guirado E, Pan XJ, Wang SH, Ross P Jr, Lafuse WP, Schlesinger LS, Turner J, Torrelles JB.

Age (Dordr). 2014 Jun;36(3):9633. doi: 10.1007/s11357-014-9633-4. Epub 2014 Mar 3.

39.

Functional characterization of exopolyphosphatase/guanosine pentaphosphate phosphohydrolase (PPX/GPPA) of Campylobacter jejuni.

Malde A, Gangaiah D, Chandrashekhar K, Pina-Mimbela R, Torrelles JB, Rajashekara G.

Virulence. 2014 May 15;5(4):521-33. doi: 10.4161/viru.28311. Epub 2014 Feb 25.

40.

Adjuvanted poly(lactic-co-glycolic) acid nanoparticle-entrapped inactivated porcine reproductive and respiratory syndrome virus vaccine elicits cross-protective immune response in pigs.

Binjawadagi B, Dwivedi V, Manickam C, Ouyang K, Wu Y, Lee LJ, Torrelles JB, Renukaradhya GJ.

Int J Nanomedicine. 2014 Jan 24;9:679-94. doi: 10.2147/IJN.S56127. eCollection 2014. Erratum in: Int J Nanomedicine. 2014;9:2259.

41.

Changes in the major cell envelope components of Mycobacterium tuberculosis during in vitro growth.

Yang L, Sinha T, Carlson TK, Keiser TL, Torrelles JB, Schlesinger LS.

Glycobiology. 2013 Aug;23(8):926-34. doi: 10.1093/glycob/cwt029. Epub 2013 Apr 10.

42.

Characterization of clinical and environmental Mycobacterium avium spp. isolates and their interaction with human macrophages.

Guirado E, Arcos J, Knaup R, Reeder R, Betz B, Cotton C, Patel T, Pfaller S, Torrelles JB, Schlesinger LS.

PLoS One. 2012;7(9):e45411. doi: 10.1371/journal.pone.0045411. Epub 2012 Sep 19.

43.

Isolation of a distinct Mycobacterium tuberculosis mannose-capped lipoarabinomannan isoform responsible for recognition by CD1b-restricted T cells.

Torrelles JB, Sieling PA, Zhang N, Keen MA, McNeil MR, Belisle JT, Modlin RL, Brennan PJ, Chatterjee D.

Glycobiology. 2012 Aug;22(8):1118-27. doi: 10.1093/glycob/cws078. Epub 2012 Apr 25.

44.

Intranasal delivery of an adjuvanted modified live porcine reproductive and respiratory syndrome virus vaccine reduces ROS production.

Binjawadagi B, Dwivedi V, Manickam C, Torrelles JB, Renukaradhya GJ.

Viral Immunol. 2011 Dec;24(6):475-82. doi: 10.1089/vim.2011.0040. Epub 2011 Nov 23.

PMID:
22111597
45.

Mycobacterium tuberculosis lipomannan blocks TNF biosynthesis by regulating macrophage MAPK-activated protein kinase 2 (MK2) and microRNA miR-125b.

Rajaram MV, Ni B, Morris JD, Brooks MN, Carlson TK, Bakthavachalu B, Schoenberg DR, Torrelles JB, Schlesinger LS.

Proc Natl Acad Sci U S A. 2011 Oct 18;108(42):17408-13. doi: 10.1073/pnas.1112660108. Epub 2011 Oct 3.

46.

Structural differences in lipomannans from pathogenic and nonpathogenic mycobacteria that impact CD1b-restricted T cell responses.

Torrelles JB, Sieling PA, Arcos J, Knaup R, Bartling C, Rajaram MV, Stenger S, Modlin RL, Schlesinger LS.

J Biol Chem. 2011 Oct 14;286(41):35438-46. doi: 10.1074/jbc.M111.232587. Epub 2011 Aug 22.

47.

Mycobacterium Tuberculosis Infection and Inflammation: what is Beneficial for the Host and for the Bacterium?

Sasindran SJ, Torrelles JB.

Front Microbiol. 2011 Jan 26;2:2. doi: 10.3389/fmicb.2011.00002. eCollection 2011.

48.

Human lung hydrolases delineate Mycobacterium tuberculosis-macrophage interactions and the capacity to control infection.

Arcos J, Sasindran SJ, Fujiwara N, Turner J, Schlesinger LS, Torrelles JB.

J Immunol. 2011 Jul 1;187(1):372-81. doi: 10.4049/jimmunol.1100823. Epub 2011 May 20.

49.

Cross-protective immunity to porcine reproductive and respiratory syndrome virus by intranasal delivery of a live virus vaccine with a potent adjuvant.

Dwivedi V, Manickam C, Patterson R, Dodson K, Murtaugh M, Torrelles JB, Schlesinger LS, Renukaradhya GJ.

Vaccine. 2011 May 23;29(23):4058-66. doi: 10.1016/j.vaccine.2011.03.006. Epub 2011 Apr 3.

PMID:
21419162
50.

Polyphosphate kinase 2: a novel determinant of stress responses and pathogenesis in Campylobacter jejuni.

Gangaiah D, Liu Z, Arcos J, Kassem II, Sanad Y, Torrelles JB, Rajashekara G.

PLoS One. 2010 Aug 17;5(8):e12142. doi: 10.1371/journal.pone.0012142.

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