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Items: 11

1.

Muscarinic Agonist Ameliorates Insulin Secretion in Wfs1-Deficient Mice.

Toots M, Reimets R, Plaas M, Vasar E.

Can J Diabetes. 2019 Mar;43(2):115-120. doi: 10.1016/j.jcjd.2018.06.007. Epub 2018 Jun 23.

PMID:
30266217
2.

Development of an allosteric inhibitor class blocking RNA elongation by the respiratory syncytial virus polymerase complex.

Cox RM, Toots M, Yoon JJ, Sourimant J, Ludeke B, Fearns R, Bourque E, Patti J, Lee E, Vernachio J, Plemper RK.

J Biol Chem. 2018 Oct 26;293(43):16761-16777. doi: 10.1074/jbc.RA118.004862. Epub 2018 Sep 11.

PMID:
30206124
3.

Preventive treatment with liraglutide protects against development of glucose intolerance in a rat model of Wolfram syndrome.

Toots M, Seppa K, Jagomäe T, Koppel T, Pallase M, Heinla I, Terasmaa A, Plaas M, Vasar E.

Sci Rep. 2018 Jul 5;8(1):10183. doi: 10.1038/s41598-018-28314-z.

4.

Orally Efficacious Broad-Spectrum Ribonucleoside Analog Inhibitor of Influenza and Respiratory Syncytial Viruses.

Yoon JJ, Toots M, Lee S, Lee ME, Ludeke B, Luczo JM, Ganti K, Cox RM, Sticher ZM, Edpuganti V, Mitchell DG, Lockwood MA, Kolykhalov AA, Greninger AL, Moore ML, Painter GR, Lowen AC, Tompkins SM, Fearns R, Natchus MG, Plemper RK.

Antimicrob Agents Chemother. 2018 Jul 27;62(8). pii: e00766-18. doi: 10.1128/AAC.00766-18. Print 2018 Aug.

5.

Mild stress induces brain region-specific alterations of selective ER stress markers' mRNA expression in Wfs1-deficient mice.

Altpere A, Raud S, Sütt S, Reimets R, Visnapuu T, Toots M, Vasar E.

Behav Brain Res. 2018 Oct 15;352:94-98. doi: 10.1016/j.bbr.2017.09.039. Epub 2017 Sep 28.

PMID:
28963041
6.

Wfs1- deficient rats develop primary symptoms of Wolfram syndrome: insulin-dependent diabetes, optic nerve atrophy and medullary degeneration.

Plaas M, Seppa K, Reimets R, Jagomäe T, Toots M, Koppel T, Vallisoo T, Nigul M, Heinla I, Meier R, Kaasik A, Piirsoo A, Hickey MA, Terasmaa A, Vasar E.

Sci Rep. 2017 Aug 31;7(1):10220. doi: 10.1038/s41598-017-09392-x.

7.

Identification of several high-risk HPV inhibitors and drug targets with a novel high-throughput screening assay.

Toots M, Ustav M Jr, Männik A, Mumm K, Tämm K, Tamm T, Ustav E, Ustav M.

PLoS Pathog. 2017 Feb 9;13(2):e1006168. doi: 10.1371/journal.ppat.1006168. eCollection 2017 Feb.

8.

The Cell Cycle Timing of Human Papillomavirus DNA Replication.

Reinson T, Henno L, Toots M, Ustav M Jr, Ustav M.

PLoS One. 2015 Jul 1;10(7):e0131675. doi: 10.1371/journal.pone.0131675. eCollection 2015.

9.

The transcription map of human papillomavirus type 18 during genome replication in U2OS cells.

Toots M, Männik A, Kivi G, Ustav M Jr, Ustav E, Ustav M.

PLoS One. 2014 Dec 30;9(12):e116151. doi: 10.1371/journal.pone.0116151. eCollection 2014.

10.

Engagement of the ATR-dependent DNA damage response at the human papillomavirus 18 replication centers during the initial amplification.

Reinson T, Toots M, Kadaja M, Pipitch R, Allik M, Ustav E, Ustav M.

J Virol. 2013 Jan;87(2):951-64. doi: 10.1128/JVI.01943-12. Epub 2012 Nov 7.

11.

Towards global patterns in the diversity and community structure of ectomycorrhizal fungi.

Tedersoo L, Bahram M, Toots M, Diédhiou AG, Henkel TW, Kjøller R, Morris MH, Nara K, Nouhra E, Peay KG, Põlme S, Ryberg M, Smith ME, Kõljalg U.

Mol Ecol. 2012 Sep;21(17):4160-70. doi: 10.1111/j.1365-294X.2012.05602.x. Epub 2012 May 9.

PMID:
22568722

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