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Items: 5

1.
2.

Clozapine and other competitive antagonists reactivate risperidone-inactivated h5-HT7 receptors: radioligand binding and functional evidence for GPCR homodimer protomer interactions.

Teitler M, Toohey N, Knight JA, Klein MT, Smith C.

Psychopharmacology (Berl). 2010 Dec;212(4):687-97. doi: 10.1007/s00213-010-2001-x. Epub 2010 Sep 9.

3.

Human 5-HT7 receptor-induced inactivation of forskolin-stimulated adenylate cyclase by risperidone, 9-OH-risperidone and other "inactivating antagonists".

Toohey N, Klein MT, Knight J, Smith C, Teitler M.

Mol Pharmacol. 2009 Sep;76(3):552-9. doi: 10.1124/mol.109.056283. Epub 2009 Jun 9.

4.

Pharmacological analysis of the novel, rapid, and potent inactivation of the human 5-Hydroxytryptamine7 receptor by risperidone, 9-OH-Risperidone, and other inactivating antagonists.

Knight JA, Smith C, Toohey N, Klein MT, Teitler M.

Mol Pharmacol. 2009 Feb;75(2):374-80. doi: 10.1124/mol.108.052084. Epub 2008 Nov 7.

5.

Risperidone irreversibly binds to and inactivates the h5-HT7 serotonin receptor.

Smith C, Rahman T, Toohey N, Mazurkiewicz J, Herrick-Davis K, Teitler M.

Mol Pharmacol. 2006 Oct;70(4):1264-70. Epub 2006 Jul 26.

PMID:
16870886

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