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Items: 4

1.

Role of Y-family translesion DNA polymerases in replication stress: Implications for new cancer therapeutic targets.

Tonzi P, Huang TT.

DNA Repair (Amst). 2019 Jun;78:20-26. doi: 10.1016/j.dnarep.2019.03.016. Epub 2019 Mar 29. Review.

PMID:
30954011
2.

Transcription shapes DNA replication initiation and termination in human cells.

Chen YH, Keegan S, Kahli M, Tonzi P, Fenyö D, Huang TT, Smith DJ.

Nat Struct Mol Biol. 2019 Jan;26(1):67-77. doi: 10.1038/s41594-018-0171-0. Epub 2018 Dec 31.

3.

Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery.

Tonzi P, Yin Y, Lee CWT, Rothenberg E, Huang TT.

Elife. 2018 Nov 13;7. pii: e41426. doi: 10.7554/eLife.41426.

4.

Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma.

Perry JA, Kiezun A, Tonzi P, Van Allen EM, Carter SL, Baca SC, Cowley GS, Bhatt AS, Rheinbay E, Pedamallu CS, Helman E, Taylor-Weiner A, McKenna A, DeLuca DS, Lawrence MS, Ambrogio L, Sougnez C, Sivachenko A, Walensky LD, Wagle N, Mora J, de Torres C, Lavarino C, Dos Santos Aguiar S, Yunes JA, Brandalise SR, Mercado-Celis GE, Melendez-Zajgla J, Cárdenas-Cardós R, Velasco-Hidalgo L, Roberts CW, Garraway LA, Rodriguez-Galindo C, Gabriel SB, Lander ES, Golub TR, Orkin SH, Getz G, Janeway KA.

Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):E5564-73. doi: 10.1073/pnas.1419260111. Epub 2014 Dec 15.

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