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Items: 36

1.

Reversible immortalisation enables genetic correction of human muscle progenitors and engineering of next-generation human artificial chromosomes for Duchenne muscular dystrophy.

Benedetti S, Uno N, Hoshiya H, Ragazzi M, Ferrari G, Kazuki Y, Moyle LA, Tonlorenzi R, Lombardo A, Chaouch S, Mouly V, Moore M, Popplewell L, Kazuki K, Katoh M, Naldini L, Dickson G, Messina G, Oshimura M, Cossu G, Tedesco FS.

EMBO Mol Med. 2018 Feb;10(2):254-275. doi: 10.15252/emmm.201607284.

2.

Isolation and Characterization of Vessel-Associated Stem/Progenitor Cells from Skeletal Muscle.

Tonlorenzi R, Rossi G, Messina G.

Methods Mol Biol. 2017;1556:149-177. doi: 10.1007/978-1-4939-6771-1_8.

PMID:
28247349
3.

Intra-arterial transplantation of HLA-matched donor mesoangioblasts in Duchenne muscular dystrophy.

Cossu G, Previtali SC, Napolitano S, Cicalese MP, Tedesco FS, Nicastro F, Noviello M, Roostalu U, Natali Sora MG, Scarlato M, De Pellegrin M, Godi C, Giuliani S, Ciotti F, Tonlorenzi R, Lorenzetti I, Rivellini C, Benedetti S, Gatti R, Marktel S, Mazzi B, Tettamanti A, Ragazzi M, Imro MA, Marano G, Ambrosi A, Fiori R, Sormani MP, Bonini C, Venturini M, Politi LS, Torrente Y, Ciceri F.

EMBO Mol Med. 2016 Dec 1;8(12):1470-1471. doi: 10.15252/emmm.201607129. No abstract available.

4.

Intra-arterial transplantation of HLA-matched donor mesoangioblasts in Duchenne muscular dystrophy.

Cossu G, Previtali SC, Napolitano S, Cicalese MP, Tedesco FS, Nicastro F, Noviello M, Roostalu U, Natali Sora MG, Scarlato M, De Pellegrin M, Godi C, Giuliani S, Ciotti F, Tonlorenzi R, Lorenzetti I, Rivellini C, Benedetti S, Gatti R, Marktel S, Mazzi B, Tettamanti A, Ragazzi M, Imro MA, Marano G, Ambrosi A, Fiori R, Sormani MP, Bonini C, Venturini M, Politi LS, Torrente Y, Ciceri F.

EMBO Mol Med. 2015 Dec;7(12):1513-28. doi: 10.15252/emmm.201505636. Erratum in: EMBO Mol Med. 2016 Dec 1;8(12 ):1470-1471.

5.

Mesoangioblast delivery of miniagrin ameliorates murine model of merosin-deficient congenital muscular dystrophy type 1A.

Domi T, Porrello E, Velardo D, Capotondo A, Biffi A, Tonlorenzi R, Amadio S, Ambrosi A, Miyagoe-Suzuki Y, Takeda S, Ruegg MA, Previtali SC.

Skelet Muscle. 2015 Sep 3;5:30. doi: 10.1186/s13395-015-0055-5. eCollection 2015.

6.

PW1/Peg3 expression regulates key properties that determine mesoangioblast stem cell competence.

Bonfanti C, Rossi G, Tedesco FS, Giannotta M, Benedetti S, Tonlorenzi R, Antonini S, Marazzi G, Dejana E, Sassoon D, Cossu G, Messina G.

Nat Commun. 2015 Mar 9;6:6364. doi: 10.1038/ncomms7364.

7.

Inflammation converts human mesoangioblasts into targets of alloreactive immune responses: implications for allogeneic cell therapy of DMD.

Noviello M, Tedesco FS, Bondanza A, Tonlorenzi R, Rosaria Carbone M, Gerli MFM, Marktel S, Napolitano S, Cicalese MP, Ciceri F, Peretti G, Cossu G, Bonini C.

Mol Ther. 2014 Jul;22(7):1342-1352. doi: 10.1038/mt.2014.62. Epub 2014 Apr 16.

8.

Corrigendum: Mesoangioblast stem cells ameliorate muscle function in dystrophic dogs.

Sampaolesi M, Blot S, D'Antona G, Granger N, Tonlorenzi R, Innocenzi A, Mognol P, Thibaud JL, Galvez BG, Barthélémy I, Perani L, Mantero S, Guttinger M, Pansarasa O, Rinaldi C, De Angelis MG, Torrente Y, Bordignon C, Bottinelli R, Cossu G.

Nature. 2013 Feb 20;494(7438):506. doi: 10.1038/nature11976. Epub 2013 Feb 20. No abstract available.

PMID:
23426261
9.

Human iPSC-derived mesoangioblasts, like their tissue-derived counterparts, suppress T cell proliferation through IDO- and PGE-2-dependent pathways.

Li O, English K, Tonlorenzi R, Cossu G, Saverio Tedesco F, Wood KJ.

F1000Res. 2013 Jan 25;2:24. doi: 10.12688/f1000research.2-24.v1. eCollection 2013.

10.

Mesoangioblasts suppress T cell proliferation through IDO and PGE-2-dependent pathways.

English K, Tonlorenzi R, Cossu G, Wood KJ.

Stem Cells Dev. 2013 Feb 1;22(3):512-23. doi: 10.1089/scd.2012.0386. Epub 2012 Oct 1.

11.

The increase of pericyte population in human neuromuscular disorders supports their role in muscle regeneration in vivo.

Díaz-Manera J, Gallardo E, de Luna N, Navas M, Soria L, Garibaldi M, Rojas-García R, Tonlorenzi R, Cossu G, Illa I.

J Pathol. 2012 Dec;228(4):544-53. doi: 10.1002/path.4083. Epub 2012 Oct 5.

PMID:
22847756
12.

Transplantation of genetically corrected human iPSC-derived progenitors in mice with limb-girdle muscular dystrophy.

Tedesco FS, Gerli MF, Perani L, Benedetti S, Ungaro F, Cassano M, Antonini S, Tagliafico E, Artusi V, Longa E, Tonlorenzi R, Ragazzi M, Calderazzi G, Hoshiya H, Cappellari O, Mora M, Schoser B, Schneiderat P, Oshimura M, Bottinelli R, Sampaolesi M, Torrente Y, Broccoli V, Cossu G.

Sci Transl Med. 2012 Jun 27;4(140):140ra89. doi: 10.1126/scitranslmed.3003541.

13.

Necdin enhances muscle reconstitution of dystrophic muscle by vessel-associated progenitors, by promoting cell survival and myogenic differentiation.

Pessina P, Conti V, Tonlorenzi R, Touvier T, Meneveri R, Cossu G, Brunelli S.

Cell Death Differ. 2012 May;19(5):827-38. doi: 10.1038/cdd.2011.160. Epub 2011 Nov 18.

14.

Stem cell-mediated transfer of a human artificial chromosome ameliorates muscular dystrophy.

Tedesco FS, Hoshiya H, D'Antona G, Gerli MF, Messina G, Antonini S, Tonlorenzi R, Benedetti S, Berghella L, Torrente Y, Kazuki Y, Bottinelli R, Oshimura M, Cossu G.

Sci Transl Med. 2011 Aug 17;3(96):96ra78. doi: 10.1126/scitranslmed.3002342.

15.

Partial dysferlin reconstitution by adult murine mesoangioblasts is sufficient for full functional recovery in a murine model of dysferlinopathy.

Díaz-Manera J, Touvier T, Dellavalle A, Tonlorenzi R, Tedesco FS, Messina G, Meregalli M, Navarro C, Perani L, Bonfanti C, Illa I, Torrente Y, Cossu G.

Cell Death Dis. 2010 Aug 5;1:e61. doi: 10.1038/cddis.2010.35.

16.

Inflammatory and alternatively activated human macrophages attract vessel-associated stem cells, relying on separate HMGB1- and MMP-9-dependent pathways.

Lolmede K, Campana L, Vezzoli M, Bosurgi L, Tonlorenzi R, Clementi E, Bianchi ME, Cossu G, Manfredi AA, Brunelli S, Rovere-Querini P.

J Leukoc Biol. 2009 May;85(5):779-87. doi: 10.1189/jlb.0908579. Epub 2009 Feb 5.

PMID:
19197071
17.

Skeletal muscle differentiation of embryonic mesoangioblasts requires pax3 activity.

Messina G, Sirabella D, Monteverde S, Galvez BG, Tonlorenzi R, Schnapp E, De Angelis L, Brunelli S, Relaix F, Buckingham M, Cossu G.

Stem Cells. 2009 Jan;27(1):157-64. doi: 10.1634/stemcells.2008-0503.

18.

Isolation and characterization of mesoangioblasts from mouse, dog, and human tissues.

Tonlorenzi R, Dellavalle A, Schnapp E, Cossu G, Sampaolesi M.

Curr Protoc Stem Cell Biol. 2007 Dec;Chapter 2:Unit 2B.1. doi: 10.1002/9780470151808.sc02b01s3.

PMID:
18785178
19.

Autologous transplantation of muscle-derived CD133+ stem cells in Duchenne muscle patients.

Torrente Y, Belicchi M, Marchesi C, D'Antona G, Cogiamanian F, Pisati F, Gavina M, Giordano R, Tonlorenzi R, Fagiolari G, Lamperti C, Porretti L, Lopa R, Sampaolesi M, Vicentini L, Grimoldi N, Tiberio F, Songa V, Baratta P, Prelle A, Forzenigo L, Guglieri M, Pansarasa O, Rinaldi C, Mouly V, Butler-Browne GS, Comi GP, Biondetti P, Moggio M, Gaini SM, Stocchetti N, Priori A, D'Angelo MG, Turconi A, Bottinelli R, Cossu G, Rebulla P, Bresolin N.

Cell Transplant. 2007;16(6):563-77.

PMID:
17912948
20.

Pericytes of human skeletal muscle are myogenic precursors distinct from satellite cells.

Dellavalle A, Sampaolesi M, Tonlorenzi R, Tagliafico E, Sacchetti B, Perani L, Innocenzi A, Galvez BG, Messina G, Morosetti R, Li S, Belicchi M, Peretti G, Chamberlain JS, Wright WE, Torrente Y, Ferrari S, Bianco P, Cossu G.

Nat Cell Biol. 2007 Mar;9(3):255-67. Epub 2007 Feb 11.

PMID:
17293855
21.

Mesoangioblast stem cells ameliorate muscle function in dystrophic dogs.

Sampaolesi M, Blot S, D'Antona G, Granger N, Tonlorenzi R, Innocenzi A, Mognol P, Thibaud JL, Galvez BG, Barthélémy I, Perani L, Mantero S, Guttinger M, Pansarasa O, Rinaldi C, Cusella De Angelis MG, Torrente Y, Bordignon C, Bottinelli R, Cossu G.

Nature. 2006 Nov 30;444(7119):574-9. Epub 2006 Nov 15. Erratum in: Nature. 2013 Feb 28;494(7438):506. Nature. 2014 Mar 13;507(7491):262.

PMID:
17108972
22.

Cell therapy of primary myopathies.

Sampaolesi M, Biressi S, Tonlorenzi R, Innocenzi A, Draghici E, Cusella de Angelis MG, Cossu G.

Arch Ital Biol. 2005 Sep;143(3-4):235-42. Review.

PMID:
16097501
23.

Human circulating AC133(+) stem cells restore dystrophin expression and ameliorate function in dystrophic skeletal muscle.

Torrente Y, Belicchi M, Sampaolesi M, Pisati F, Meregalli M, D'Antona G, Tonlorenzi R, Porretti L, Gavina M, Mamchaoui K, Pellegrino MA, Furling D, Mouly V, Butler-Browne GS, Bottinelli R, Cossu G, Bresolin N.

J Clin Invest. 2004 Jul;114(2):182-95.

24.

Msx2 and necdin combined activities are required for smooth muscle differentiation in mesoangioblast stem cells.

Brunelli S, Tagliafico E, De Angelis FG, Tonlorenzi R, Baesso S, Ferrari S, Niinobe M, Yoshikawa K, Schwartz RJ, Bozzoni I, Ferrari S, Cossu G.

Circ Res. 2004 Jun 25;94(12):1571-8. Epub 2004 May 20.

PMID:
15155529
25.

Extracellular HMGB1, a signal of tissue damage, induces mesoangioblast migration and proliferation.

Palumbo R, Sampaolesi M, De Marchis F, Tonlorenzi R, Colombetti S, Mondino A, Cossu G, Bianchi ME.

J Cell Biol. 2004 Feb 2;164(3):441-9. Epub 2004 Jan 26.

26.

Cell therapy of alpha-sarcoglycan null dystrophic mice through intra-arterial delivery of mesoangioblasts.

Sampaolesi M, Torrente Y, Innocenzi A, Tonlorenzi R, D'Antona G, Pellegrino MA, Barresi R, Bresolin N, De Angelis MG, Campbell KP, Bottinelli R, Cossu G.

Science. 2003 Jul 25;301(5632):487-92. Epub 2003 Jul 10.

27.

Alport syndrome and mental retardation: clinical and genetic dissection of the contiguous gene deletion syndrome in Xq22.3 (ATS-MR).

Meloni I, Vitelli F, Pucci L, Lowry RB, Tonlorenzi R, Rossi E, Ventura M, Rizzoni G, Kashtan CE, Pober B, Renieri A.

J Med Genet. 2002 May;39(5):359-65. No abstract available.

28.

Spectrum of mutations in fucosidosis.

Willems PJ, Seo HC, Coucke P, Tonlorenzi R, O'Brien JS.

Eur J Hum Genet. 1999 Jan;7(1):60-7. Review.

29.

Rox, a novel bHLHZip protein expressed in quiescent cells that heterodimerizes with Max, binds a non-canonical E box and acts as a transcriptional repressor.

Meroni G, Reymond A, Alcalay M, Borsani G, Tanigami A, Tonlorenzi R, Lo Nigro C, Messali S, Zollo M, Ledbetter DH, Brent R, Ballabio A, Carrozzo R.

EMBO J. 1997 May 15;16(10):2892-906. Erratum in: EMBO J 1997 Oct 1;16(19):6055.

30.

Two new nonsense mutations (Q80X; Q389X) in patients with severe Hunter syndrome (mucopolysaccharidosis type II.)

Carrozzo R, Tonlorenzi R, Corsolini F, Gatti R.

Hum Mutat. 1996;7(2):184-5. No abstract available.

PMID:
8829647
31.

A missense mutation (S63L) in alpha-L-fucosidase is responsible for fucosidosis in an Italian patient.

Seo HC, Yang M, Tonlorenzi R, Willems PJ, Kim AH, Filocamo M, Gatti R, DiCioccio RA, O'Brien JS.

Hum Mol Genet. 1994 Nov;3(11):2065-6. No abstract available.

PMID:
7874128
32.

Kallmann syndrome gene on the X and Y chromosomes: implications for evolutionary divergence of human sex chromosomes.

Incerti B, Guioli S, Pragliola A, Zanaria E, Borsani G, Tonlorenzi R, Bardoni B, Franco B, Wheeler D, Ballabio A, et al.

Nat Genet. 1992 Dec;2(4):311-4.

PMID:
1303285
33.

A gene deleted in Kallmann's syndrome shares homology with neural cell adhesion and axonal path-finding molecules.

Franco B, Guioli S, Pragliola A, Incerti B, Bardoni B, Tonlorenzi R, Carrozzo R, Maestrini E, Pieretti M, Taillon-Miller P, Brown CJ, Willard HF, Lawrence C, Graziella Persico M, Camerino G, Ballabio A.

Nature. 1991 Oct 10;353(6344):529-36.

PMID:
1922361
34.

Rapid assembly of lambda phage contigs within YAC clones.

Pieretti M, Tonlorenzi R, Ballabio A.

Nucleic Acids Res. 1991 May 25;19(10):2795-6. No abstract available.

35.

Characterization of a murine gene expressed from the inactive X chromosome.

Borsani G, Tonlorenzi R, Simmler MC, Dandolo L, Arnaud D, Capra V, Grompe M, Pizzuti A, Muzny D, Lawrence C, Willard HF, Avner P, Ballabio A.

Nature. 1991 May 23;351(6324):325-9.

PMID:
2034278
36.

A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome.

Brown CJ, Ballabio A, Rupert JL, Lafreniere RG, Grompe M, Tonlorenzi R, Willard HF.

Nature. 1991 Jan 3;349(6304):38-44.

PMID:
1985261

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