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Items: 49

1.

Dative Directing Group Effects in Ti-Catalyzed [2+2+1] Pyrrole Synthesis: Chemo- and Regioselective Alkyne Heterocoupling.

Chiu HC, See XY, Tonks IA.

ACS Catal. 2019 Jan 4;9(1):216-223. doi: 10.1021/acscatal.8b04669. Epub 2018 Nov 29.

2.

Diverse Reactivity of Diazatitanacyclohexenes: Coupling Reactions of 2H-Azirines Mediated by Titanium(II).

Desnoyer AN, See XY, Tonks IA.

Organometallics. 2018 Dec 10;37(23):4327-4331. doi: 10.1021/acs.organomet.8b00522. Epub 2018 Sep 10.

3.

Synthesis of Pyridylimido Complexes of Tantalum and Niobium by Reductive Cleavage of the N═N Bond of 2,2'-Azopyridine: Precursors for Early-Late Heterobimetallic Complexes.

Kawakita K, Kakiuchi Y, Beaumier EP, Tonks IA, Tsurugi H, Mashima K.

Inorg Chem. 2019 Nov 18;58(22):15155-15165. doi: 10.1021/acs.inorgchem.9b02043. Epub 2019 Sep 25.

PMID:
31553585
4.

The 4-Electron Cleavage of a N═N Double Bond by a Trimetallic TiNi2 Complex.

Dunn PL, Chatterjee S, MacMillan SN, Pearce AJ, Lancaster KM, Tonks IA.

Inorg Chem. 2019 Sep 3;58(17):11762-11772. doi: 10.1021/acs.inorgchem.9b01805. Epub 2019 Aug 22.

PMID:
31436979
5.

Group 4 Diarylmetallocenes as Bespoke Aryne Precursors for Titanium-Catalyzed [2 + 2 + 2] Cycloaddition of Arynes and Alkynes.

Reiner BR, Tonks IA.

Inorg Chem. 2019 Aug 19;58(16):10508-10515. doi: 10.1021/acs.inorgchem.9b01082. Epub 2019 Jun 12.

PMID:
31188580
6.

Modern applications of low-valent early transition metals in synthesis and catalysis.

Beaumier EP, Pearce AJ, See XY, Tonks IA.

Nat Rev Chem. 2019 Jan;3(1):15-34. doi: 10.1038/s41570-018-0059-x. Epub 2018 Nov 30.

7.

Bis(imido)vanadium(V)-Catalyzed [2+2+1] Coupling of Alkynes and Azobenzenes Giving Multisubstituted Pyrroles.

Kawakita K, Beaumier EP, Kakiuchi Y, Tsurugi H, Tonks IA, Mashima K.

J Am Chem Soc. 2019 Mar 13;141(10):4194-4198. doi: 10.1021/jacs.8b13390. Epub 2019 Feb 11.

8.

Smchd1 regulates long-range chromatin interactions on the inactive X chromosome and at Hox clusters.

Jansz N, Keniry A, Trussart M, Bildsoe H, Beck T, Tonks ID, Mould AW, Hickey P, Breslin K, Iminitoff M, Ritchie ME, McGlinn E, Kay GF, Murphy JM, Blewitt ME.

Nat Struct Mol Biol. 2018 Sep;25(9):766-777. doi: 10.1038/s41594-018-0111-z. Epub 2018 Aug 20.

PMID:
30127357
9.

Oxidative nitrene transfer from azides to alkynes via Ti(ii)/Ti(iv) redox catalysis: formal [2+2+1] synthesis of pyrroles.

Pearce AJ, See XY, Tonks IA.

Chem Commun (Camb). 2018 Jun 19;54(50):6891-6894. doi: 10.1039/c8cc02623h.

10.

Mechanism of Ti-Catalyzed Oxidative Nitrene Transfer in [2 + 2 + 1] Pyrrole Synthesis from Alkynes and Azobenzene.

Davis-Gilbert ZW, Wen X, Goodpaster JD, Tonks IA.

J Am Chem Soc. 2018 Jun 13;140(23):7267-7281. doi: 10.1021/jacs.8b03546. Epub 2018 May 31.

11.

Trimethylsilyl-Protected Alkynes as Selective Cross-Coupling Partners in Titanium-Catalyzed [2+2+1] Pyrrole Synthesis.

Chiu HC, Tonks IA.

Angew Chem Int Ed Engl. 2018 May 22;57(21):6090-6094. doi: 10.1002/anie.201800595. Epub 2018 Apr 25.

12.

Organometallic mechanisms: Measuring up with the early metals.

Tonks IA.

Nat Chem. 2017 Aug 24;9(9):834-836. doi: 10.1038/nchem.2851. No abstract available.

PMID:
28837167
13.

Titanium redox catalysis: insights and applications of an earth-abundant base metal.

Davis-Gilbert ZW, Tonks IA.

Dalton Trans. 2017 Sep 12;46(35):11522-11528. doi: 10.1039/c7dt02319g.

14.

Generation of TiII Alkyne Trimerization Catalysts in the Absence of Strong Metal Reductants.

See XY, Beaumier EP, Davis-Gilbert ZW, Dunn PL, Larsen JA, Pearce AJ, Wheeler TA, Tonks IA.

Organometallics. 2017 Apr 10;36(7):1383-1390. doi: 10.1021/acs.organomet.7b00096. Epub 2017 Mar 29.

15.

Ethylene polymerization catalyzed by bridging Ni/Zn heterobimetallics.

Chiu HC, Koley A, Dunn PL, Hue RJ, Tonks IA.

Dalton Trans. 2017 May 2;46(17):5513-5517. doi: 10.1039/c7dt00222j.

PMID:
28317966
16.

Melanocyte transformation requires complete loss of all pocket protein function via a mechanism that mitigates the need for MAPK pathway activation.

Tonks ID, Mukhopadhyay P, Schroder WA, Sorolla A, Mould AW, Handoko HY, Ferguson B, Muller HK, Keith P, Hayward NK, Walker GJ, Kay GF.

Oncogene. 2017 Jun 29;36(26):3789-3795. doi: 10.1038/onc.2016.511. Epub 2017 Feb 13.

PMID:
28192409
17.

Ti-Catalyzed Multicomponent Oxidative Carboamination of Alkynes with Alkenes and Diazenes.

Davis-Gilbert ZW, Yao LJ, Tonks IA.

J Am Chem Soc. 2016 Nov 9;138(44):14570-14573. Epub 2016 Oct 28.

18.

Redox Non-Innocent Behavior of a Terminal Iridium Hydrazido(2-) Triple Bond.

Pearce AJ, Cassabaum AA, Gast GE, Frontiera RR, Tonks IA.

Angew Chem Int Ed Engl. 2016 Oct 10;55(42):13169-13173. doi: 10.1002/anie.201607648.

19.

Structure and bonding of group 4-nickel heterobimetallics supported by 2-(diphenylphosphino)pyrrolide ligands.

Dunn PL, Carlson RK, Gagliardi L, Tonks IA.

Dalton Trans. 2016 Jun 14;45(24):9892-901. doi: 10.1039/c6dt00431h.

PMID:
26952589
20.

Catalytic formal [2+2+1] synthesis of pyrroles from alkynes and diazenes via Ti(II)/Ti(IV) redox catalysis.

Gilbert ZW, Hue RJ, Tonks IA.

Nat Chem. 2016 Jan;8(1):63-8. doi: 10.1038/nchem.2386. Epub 2015 Nov 2.

PMID:
26673265
21.
22.

Smchd1 regulates a subset of autosomal genes subject to monoallelic expression in addition to being critical for X inactivation.

Mould AW, Pang Z, Pakusch M, Tonks ID, Stark M, Carrie D, Mukhopadhyay P, Seidel A, Ellis JJ, Deakin J, Wakefield MJ, Krause L, Blewitt ME, Kay GF.

Epigenetics Chromatin. 2013 Jul 2;6(1):19. doi: 10.1186/1756-8935-6-19.

23.

Brca1 is involved in establishing murine pigmentation in a p53 and developmentally specific manner.

Tonks ID, Walker GJ, Mould AW, Ferguson B, Keith P, Hayward NK, Kay GF.

Pigment Cell Melanoma Res. 2012 Jul;25(4):530-2. doi: 10.1111/j.1755-148X.2012.01009.x. Epub 2012 Jun 1. No abstract available.

PMID:
22540872
24.

Groups 5 and 6 terminal hydrazido(2-) complexes: N(β) substituent effects on ligand-to-metal charge-transfer energies and oxidation states.

Tonks IA, Durrell AC, Gray HB, Bercaw JE.

J Am Chem Soc. 2012 May 2;134(17):7301-4. doi: 10.1021/ja302275j. Epub 2012 Apr 18.

PMID:
22506581
25.

The A-repeat links ASF/SF2-dependent Xist RNA processing with random choice during X inactivation.

Royce-Tolland ME, Andersen AA, Koyfman HR, Talbot DJ, Wutz A, Tonks ID, Kay GF, Panning B.

Nat Struct Mol Biol. 2010 Aug;17(8):948-54. doi: 10.1038/nsmb.1877. Epub 2010 Jul 25.

26.

Melanocyte homeostasis in vivo tolerates Rb1 loss in a developmentally independent fashion.

Tonks ID, Mould AW, Schroder WA, Hacker E, Bosenberg M, Hayward NK, Walker GJ, Kay GF.

Pigment Cell Melanoma Res. 2010 Aug;23(4):564-70. doi: 10.1111/j.1755-148X.2010.00722.x. Epub 2010 May 26.

PMID:
20518858
27.

(dme)MCl3(NNPh2) (dme = dimethoxyethane; M = Nb, Ta): a versatile synthon for [Ta=NNPh2] hydrazido(2-) complexes.

Tonks IA, Bercaw JE.

Inorg Chem. 2010 May 17;49(10):4648-56. doi: 10.1021/ic1004193.

PMID:
20402474
28.

Dual loss of rb1 and Trp53 in the adrenal medulla leads to spontaneous pheochromocytoma.

Tonks ID, Mould AW, Schroder WA, Cotterill A, Hayward NK, Walker GJ, Kay GF.

Neoplasia. 2010 Mar;12(3):235-43.

29.

2-Mercapto-1-t-butylimidazolyl as a Bridging Ligand: Synthesis and Structural Characterization of Nickel and Palladium Paddlewheel Complexes.

Pang K, Figueroa JS, Tonks IA, Sattler W, Parkin G.

Inorganica Chim Acta. 2009 Sep 15;362(12):4609-4615.

30.

The glycosylphosphatidylinositol-anchored serine protease PRSS21 (testisin) imparts murine epididymal sperm cell maturation and fertilizing ability.

Netzel-Arnett S, Bugge TH, Hess RA, Carnes K, Stringer BW, Scarman AL, Hooper JD, Tonks ID, Kay GF, Antalis TM.

Biol Reprod. 2009 Nov;81(5):921-32. doi: 10.1095/biolreprod.109.076273. Epub 2009 Jul 1.

31.

Amine, amido, and imido complexes of tantalum supported by a pyridine-linked bis(phenolate) pincer ligand: Ta-N pi-bonding influences pincer ligand geometry.

Tonks IA, Henling LM, Day MW, Bercaw JE.

Inorg Chem. 2009 Jun 15;48(12):5096-105. doi: 10.1021/ic802234x.

PMID:
19422195
32.

Dual loss of Rb1 and Trp53 in melanocytes perturbs melanocyte homeostasis and genetic stability in vitro but does not cause melanoma or pigmentation defects in vivo.

Tonks ID, Mould A, Nurcombe V, Cool SM, Walker GJ, Hacker E, Keith P, Schroder WA, Cotterill A, Hayward NK, Kay GF.

Pigment Cell Melanoma Res. 2009 Jun;22(3):328-30. doi: 10.1111/j.1755-148X.2009.00560.x. Epub 2009 Feb 25. No abstract available.

PMID:
19243574
33.

Tissue-specific ablation of Prkar1a causes schwannomas by suppressing neurofibromatosis protein production.

Jones GN, Tep C, Towns WH 2nd, Mihai G, Tonks ID, Kay GF, Schmalbrock PM, Stemmer-Rachamimov AO, Yoon SO, Kirschner LS.

Neoplasia. 2008 Nov;10(11):1213-21.

34.

Generation and characterization of EphA1 receptor tyrosine kinase reporter knockout mice.

Duffy SL, Coulthard MG, Spanevello MD, Herath NI, Yeadon TM, McCarron JK, Carter JC, Tonks ID, Kay GF, Phillips GE, Boyd AW.

Genesis. 2008 Oct;46(10):553-61. doi: 10.1002/dvg.20434.

PMID:
18802966
35.

Lack of augmentation of tumor spectrum or severity in dual heterozygous Men1 and Rb1 knockout mice.

Loffler KA, Biondi CA, Gartside MG, Serewko-Auret MM, Duncan R, Tonks ID, Mould AW, Waring P, Muller HK, Kay GF, Hayward NK.

Oncogene. 2007 Jun 7;26(27):4009-17. Epub 2006 Dec 18.

PMID:
17173065
36.

Pocket protein function in melanocyte homeostasis and neoplasia.

Tonks ID, Hayward NK, Kay GF.

Pigment Cell Res. 2006 Aug;19(4):260-83. Review.

PMID:
16827746
37.

Transgenic overexpression of vascular endothelial growth factor-B isoforms by endothelial cells potentiates postnatal vessel growth in vivo and in vitro.

Mould AW, Greco SA, Cahill MM, Tonks ID, Bellomo D, Patterson C, Zournazi A, Nash A, Scotney P, Hayward NK, Kay GF.

Circ Res. 2005 Sep 16;97(6):e60-70. Epub 2005 Aug 18. Erratum in: Circ Res. 2005 Sep 30;97(7):e72.

PMID:
16109918
38.

Melanocytes in conditional Rb-/- mice are normal in vivo but exhibit proliferation and pigmentation defects in vitro.

Tonks ID, Hacker E, Irwin N, Muller HK, Keith P, Mould A, Zournazi A, Pavey S, Hayward NK, Walker G, Kay GF.

Pigment Cell Res. 2005 Aug;18(4):252-64.

PMID:
16029419
39.

Inactivation of the murine Transferrin Receptor 2 gene using the Cre recombinase: loxP system.

Wallace DF, Tonks ID, Zournazi A, Kay GF, Subramaniam VN.

Genesis. 2004 May;39(1):38-41.

PMID:
15124225
40.

Tyrosinase-Cre mice for tissue-specific gene ablation in neural crest and neuroepithelial-derived tissues.

Tonks ID, Nurcombe V, Paterson C, Zournazi A, Prather C, Mould AW, Kay GF.

Genesis. 2003 Nov;37(3):131-8.

PMID:
14595836
41.

Vegfb gene knockout mice display reduced pathology and synovial angiogenesis in both antigen-induced and collagen-induced models of arthritis.

Mould AW, Tonks ID, Cahill MM, Pettit AR, Thomas R, Hayward NK, Kay GF.

Arthritis Rheum. 2003 Sep;48(9):2660-9.

42.

Pex13 inactivation in the mouse disrupts peroxisome biogenesis and leads to a Zellweger syndrome phenotype.

Maxwell M, Bjorkman J, Nguyen T, Sharp P, Finnie J, Paterson C, Tonks I, Paton BC, Kay GF, Crane DI.

Mol Cell Biol. 2003 Aug;23(16):5947-57.

43.

Conditional inactivation of the peroxisome biogenesis Pex13 gene by Cre-loxP excision.

Bjorkman J, Tonks I, Maxwell MA, Paterson C, Kay GF, Crane DI.

Genesis. 2002 Feb;32(2):179-80. No abstract available.

PMID:
11857814
44.

Targeting and conditional inactivation of the murine Men1 locus using the Cre recombinase: loxP system.

Biondi C, Gartside M, Tonks I, Paterson C, Hayward NK, Kay GF.

Genesis. 2002 Feb;32(2):150-1. No abstract available.

PMID:
11857805
45.

Mice lacking the vascular endothelial growth factor-B gene (Vegfb) have smaller hearts, dysfunctional coronary vasculature, and impaired recovery from cardiac ischemia.

Bellomo D, Headrick JP, Silins GU, Paterson CA, Thomas PS, Gartside M, Mould A, Cahill MM, Tonks ID, Grimmond SM, Townson S, Wells C, Little M, Cummings MC, Hayward NK, Kay GF.

Circ Res. 2000 Feb 4;86(2):E29-35.

PMID:
10666423
46.

Inhibition of melanin synthesis by cystamine in human melanoma cells.

Qiu L, Zhang M, Sturm RA, Gardiner B, Tonks I, Kay G, Parsons PG.

J Invest Dermatol. 2000 Jan;114(1):21-7.

47.

Multiple splicing variants of cdc25B regulate G2/M progression.

Forrest AR, McCormack AK, DeSouza CP, Sinnamon JM, Tonks ID, Hayward NK, Ellem KA, Gabrielli BG.

Biochem Biophys Res Commun. 1999 Jul 5;260(2):510-5.

PMID:
10403798
48.

Cytoplasmic accumulation of cdc25B phosphatase in mitosis triggers centrosomal microtubule nucleation in HeLa cells.

Gabrielli BG, De Souza CP, Tonks ID, Clark JM, Hayward NK, Ellem KA.

J Cell Sci. 1996 May;109 ( Pt 5):1081-93.

49.

The human cell cycle gene CDC25B is located at 20p13.

Lane SA, Baker E, Sutherland GR, Tonks I, Hayward N, Ellem K.

Genomics. 1993 Mar;15(3):693-4. No abstract available.

PMID:
8468065

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