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Items: 21


Fungicidal Potency and Mechanisms of θ-Defensins against Multidrug-Resistant Candida Species.

Basso V, Garcia A, Tran DQ, Schaal JB, Tran P, Ngole D, Aqeel Y, Tongaonkar P, Ouellette AJ, Selsted ME.

Antimicrob Agents Chemother. 2018 May 25;62(6). pii: e00111-18. doi: 10.1128/AAC.00111-18. Print 2018 Jun.


Macrocyclic θ-defensins suppress tumor necrosis factor-α (TNF-α) shedding by inhibition of TNF-α-converting enzyme.

Schaal JB, Maretzky T, Tran DQ, Tran PA, Tongaonkar P, Blobel CP, Ouellette AJ, Selsted ME.

J Biol Chem. 2018 Feb 23;293(8):2725-2734. doi: 10.1074/jbc.RA117.000793. Epub 2018 Jan 9.


Suppression and resolution of autoimmune arthritis by rhesus θ-defensin-1, an immunomodulatory macrocyclic peptide.

Schaal JB, Tran DQ, Subramanian A, Patel R, Laragione T, Roberts KD, Trinh K, Tongaonkar P, Tran PA, Minond D, Fields GB, Beringer P, Ouellette AJ, Gulko PS, Selsted ME.

PLoS One. 2017 Nov 16;12(11):e0187868. doi: 10.1371/journal.pone.0187868. eCollection 2017.


Rhesus macaque θ-defensin RTD-1 inhibits proinflammatory cytokine secretion and gene expression by inhibiting the activation of NF-κB and MAPK pathways.

Tongaonkar P, Trinh KK, Schaal JB, Tran D, Gulko PS, Ouellette AJ, Selsted ME.

J Leukoc Biol. 2015 Dec;98(6):1061-70. doi: 10.1189/jlb.3A0315-102R. Epub 2015 Aug 12.


Rhesus macaque theta defensins suppress inflammatory cytokines and enhance survival in mouse models of bacteremic sepsis.

Schaal JB, Tran D, Tran P, Ösapay G, Trinh K, Roberts KD, Brasky KM, Tongaonkar P, Ouellette AJ, Selsted ME.

PLoS One. 2012;7(12):e51337. doi: 10.1371/journal.pone.0051337. Epub 2012 Dec 6.


High fidelity processing and activation of the human α-defensin HNP1 precursor by neutrophil elastase and proteinase 3.

Tongaonkar P, Golji AE, Tran P, Ouellette AJ, Selsted ME.

PLoS One. 2012;7(3):e32469. doi: 10.1371/journal.pone.0032469. Epub 2012 Mar 20.


Rhesus macaque θ-defensin isoforms: expression, antimicrobial activities, and demonstration of a prominent role in neutrophil granule microbicidal activities.

Tongaonkar P, Tran P, Roberts K, Schaal J, Osapay G, Tran D, Ouellette AJ, Selsted ME.

J Leukoc Biol. 2011 Feb;89(2):283-90. doi: 10.1189/jlb.0910535. Epub 2010 Nov 17.


SDF2L1, a component of the endoplasmic reticulum chaperone complex, differentially interacts with {alpha}-, {beta}-, and {theta}-defensin propeptides.

Tongaonkar P, Selsted ME.

J Biol Chem. 2009 Feb 27;284(9):5602-9. doi: 10.1074/jbc.M806664200. Epub 2008 Dec 24.


Transcription of multiple yeast ribosomal DNA genes requires targeting of UAF to the promoter by Uaf30.

Hontz RD, French SL, Oakes ML, Tongaonkar P, Nomura M, Beyer AL, Smith JS.

Mol Cell Biol. 2008 Nov;28(21):6709-19. doi: 10.1128/MCB.00703-08. Epub 2008 Sep 2.


Histones are required for transcription of yeast rRNA genes by RNA polymerase I.

Tongaonkar P, French SL, Oakes ML, Vu L, Schneider DA, Beyer AL, Nomura M.

Proc Natl Acad Sci U S A. 2005 Jul 19;102(29):10129-34. Epub 2005 Jul 7.


Rad23 stabilizes Rad4 from degradation by the Ub/proteasome pathway.

Ortolan TG, Chen L, Tongaonkar P, Madura K.

Nucleic Acids Res. 2004 Dec 15;32(22):6490-500. Print 2004.


SIR2 regulates recombination between different rDNA repeats, but not recombination within individual rRNA genes in yeast.

Kobayashi T, Horiuchi T, Tongaonkar P, Vu L, Nomura M.

Cell. 2004 May 14;117(4):441-53.


Purification and assay of upstream activation factor, core factor, Rrn3p, and yeast RNA polymerase I.

Tongaonkar P, Dodd JA, Nomura M.

Methods Enzymol. 2003;370:109-20. No abstract available.


The DNA repair protein rad23 is a negative regulator of multi-ubiquitin chain assembly.

Ortolan TG, Tongaonkar P, Lambertson D, Chen L, Schauber C, Madura K.

Nat Cell Biol. 2000 Sep;2(9):601-8.


Evidence for an interaction between ubiquitin-conjugating enzymes and the 26S proteasome.

Tongaonkar P, Chen L, Lambertson D, Ko B, Madura K.

Mol Cell Biol. 2000 Jul;20(13):4691-8.


Sequence elements that contribute to the degradation of yeast G alpha.

Schauber C, Chen L, Tongaonkar P, Vega I, Madura K.

Genes Cells. 1998 May;3(5):307-19.


Reconstituting ubiquitination reactions with affinity-purified components and 32P-ubiquitin.

Tongaonkar P, Madura K.

Anal Biochem. 1998 Jul 1;260(2):135-41.


Rad23 links DNA repair to the ubiquitin/proteasome pathway.

Schauber C, Chen L, Tongaonkar P, Vega I, Lambertson D, Potts W, Madura K.

Nature. 1998 Feb 12;391(6668):715-8.


A semi-empirical method for prediction of antigenic determinants on protein antigens.

Kolaskar AS, Tongaonkar PC.

FEBS Lett. 1990 Dec 10;276(1-2):172-4.

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