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Challenging immunodominance of influenza-specific CD8+ T cell responses restricted by the risk-associated HLA-A*68:01 allomorph.

van de Sandt CE, Clemens EB, Grant EJ, Rowntree LC, Sant S, Halim H, Crowe J, Cheng AC, Kotsimbos TC, Richards M, Miller A, Tong SYC, Rossjohn J, Nguyen THO, Gras S, Chen W, Kedzierska K.

Nat Commun. 2019 Dec 6;10(1):5579. doi: 10.1038/s41467-019-13346-4.


Point of care and oral fluid Hepatitis B testing in remote Indigenous communities of northern Australia.

Sullivan RP, Davies J, Binks P, Dhurrkay RG, Gurruwiwi GG, Bukulatjpi SM, McKinnon M, Hosking K, Littlejohn M, Jackson K, Locarnini S, Davis JS, Tong SY.

J Viral Hepat. 2019 Nov 29. doi: 10.1111/jvh.13243. [Epub ahead of print]


Evolution and Global Transmission of a Multidrug-Resistant, Community-Associated Methicillin-Resistant Staphylococcus aureus Lineage from the Indian Subcontinent.

Steinig EJ, Duchene S, Robinson DA, Monecke S, Yokoyama M, Laabei M, Slickers P, Andersson P, Williamson D, Kearns A, Goering RV, Dickson E, Ehricht R, Ip M, O'Sullivan MVN, Coombs GW, Petersen A, Brennan G, Shore AC, Coleman DC, Pantosti A, de Lencastre H, Westh H, Kobayashi N, Heffernan H, Strommenger B, Layer F, Weber S, Aamot HV, Skakni L, Peacock SJ, Sarovich D, Harris S, Parkhill J, Massey RC, Holden MTG, Bentley SD, Tong SYC.

MBio. 2019 Nov 26;10(6). pii: e01105-19. doi: 10.1128/mBio.01105-19.


Longitudinal analysis of group A Streptococcus emm types and emm clusters in a high prevalence setting reveals past infection does not prevent future infection.

Campbell PT, Tong SYC, Geard N, Davies MR, Worthing KA, Lacey JA, Smeesters PR, Batzloff MR, Kado J, Jenney AWJ, McVernon J, Steer AC.

J Infect Dis. 2019 Nov 21. pii: jiz615. doi: 10.1093/infdis/jiz615. [Epub ahead of print]


SToP (See, Treat, Prevent) skin sores and scabies trial: study protocol for a cluster randomised, stepped-wedge trial for skin disease control in remote Western Australia.

Mullane MJ, Barnett TC, Cannon JW, Carapetis JR, Christophers R, Coffin J, Jones MA, Marsh JA, Mc Loughlin F, O'Donnell V, Pavlos R, Smith B, Steer AC, Tong SYC, Walker R, Bowen AC.

BMJ Open. 2019 Sep 24;9(9):e030635. doi: 10.1136/bmjopen-2019-030635.


Perinatal risk factors associated with skin infection hospitalisation in Western Australian Aboriginal and Non-Aboriginal children.

Barnes R, Bowen AC, Walker R, Tong SYC, McVernon J, Campbell PT, Fathima P, de Klerk NH, Wu Y, Blyth CC, Carapetis JR, Moore HC.

Paediatr Perinat Epidemiol. 2019 Sep;33(5):374-383. doi: 10.1111/ppe.12573. Epub 2019 Sep 12.


Correction to "Pt-like Hydrogen Evolution Electrocatalysis on PANI/CoP Hybrid Nanowires by Weakening the Shackles of Hydrogen Ions on the Surfaces of Catalysts".

Feng JX, Tong SY, Tong YX, Li GR.

J Am Chem Soc. 2019 Aug 28;141(34):13698. doi: 10.1021/jacs.9b06907. Epub 2019 Aug 20. No abstract available.


When Ventricular Cerebrospinal Fluid Assessment Misleads: Basal Meningitis and the Importance of Lumbar Puncture Sampling.

Khan SF, Macauley T, Tong SYC, Xie O, Hughes C, Hall NDP, Mahanty S, Jennens I, Street AC.

Open Forum Infect Dis. 2019 Jul 1;6(7). pii: ofz324. doi: 10.1093/ofid/ofz324.


The AMPK-Parkin axis negatively regulates necroptosis and tumorigenesis by inhibiting the necrosome.

Lee SB, Kim JJ, Han SA, Fan Y, Guo LS, Aziz K, Nowsheen S, Kim SS, Park SY, Luo Q, Chung JO, Choi SI, Aziz A, Yin P, Tong SY, Fiesel FC, Springer W, Zhang JS, Lou Z.

Nat Cell Biol. 2019 Aug;21(8):940-951. doi: 10.1038/s41556-019-0356-8. Epub 2019 Jul 29.


Author Correction: Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics.

Davies MR, McIntyre L, Mutreja A, Lacey JA, Lees JA, Towers RJ, DuchĂȘne S, Smeesters PR, Frost HR, Price DJ, Holden MTG, David S, Giffard PM, Worthing KA, Seale AC, Berkley JA, Harris SR, Rivera-Hernandez T, Berking O, Cork AJ, Torres RSLA, Lithgow T, Strugnell RA, Bergmann R, Nitsche-Schmitz P, Chhatwal GS, Bentley SD, Fraser JD, Moreland NJ, Carapetis JR, Steer AC, Parkhill J, Saul A, Williamson DA, Currie BJ, Tong SYC, Dougan G, Walker MJ.

Nat Genet. 2019 Aug;51(8):1295. doi: 10.1038/s41588-019-0482-z.


Infectious Diseases Clinician's Variation in the Management of Pediatric Staphylococcus aureus Bacteraemia and Equipoise for Clinical Trials.

Campbell AJ, Tong SYC, Davis JS, Munro APS, Blyth CC, Bowen AC.

Front Pediatr. 2019 Jun 18;7:249. doi: 10.3389/fped.2019.00249. eCollection 2019.


Concerns for efficacy of a 30-valent M-protein-based Streptococcus pyogenes vaccine in regions with high rates of rheumatic heart disease.

Giffard PM, Tong SYC, Holt DC, Ralph AP, Currie BJ.

PLoS Negl Trop Dis. 2019 Jul 3;13(7):e0007511. doi: 10.1371/journal.pntd.0007511. eCollection 2019 Jul.


CASSETTE-clindamycin adjunctive therapy for severe Staphylococcus aureus treatment evaluation: study protocol for a randomised controlled trial.

Dotel R, Tong SYC, Bowen A, Nelson JN, O'Sullivan MVN, Campbell AJ, McMullan BJ, Britton PN, Francis JR, Eisen DP, Robinson O, Manning L, Davis JS.

Trials. 2019 Jun 13;20(1):353. doi: 10.1186/s13063-019-3452-y.


Benzylpenicillin versus flucloxacillin for penicillin-susceptible Staphylococcus aureus bloodstream infections from a large retrospective cohort study.

Henderson A, Harris P, Hartel G, Paterson D, Turnidge J, Davis JS, Tong SYC.

Int J Antimicrob Agents. 2019 Oct;54(4):491-495. doi: 10.1016/j.ijantimicag.2019.05.020. Epub 2019 Jun 7.


An urgent need for antimicrobial stewardship in Indigenous rural and remote primary health care.

Bowen AC, Daveson K, Anderson L, Tong SY.

Med J Aust. 2019 Jul;211(1):9-11.e1. doi: 10.5694/mja2.50216. Epub 2019 Jun 3. No abstract available.


Early transthoracic echocardiography has useful prognostic value in left-sided native valve endocarditis despite limited diagnostic performance.

Heriot GS, Newcomb A, Darby J, Wilson A, Tong SYC, Cheng AC, Liew D.

Eur J Clin Microbiol Infect Dis. 2019 Aug;38(8):1569-1575. doi: 10.1007/s10096-019-03589-w. Epub 2019 May 28.


Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics.

Davies MR, McIntyre L, Mutreja A, Lacey JA, Lees JA, Towers RJ, DuchĂȘne S, Smeesters PR, Frost HR, Price DJ, Holden MTG, David S, Giffard PM, Worthing KA, Seale AC, Berkley JA, Harris SR, Rivera-Hernandez T, Berking O, Cork AJ, Torres RSLA, Lithgow T, Strugnell RA, Bergmann R, Nitsche-Schmitz P, Chhatwal GS, Bentley SD, Fraser JD, Moreland NJ, Carapetis JR, Steer AC, Parkhill J, Saul A, Williamson DA, Currie BJ, Tong SYC, Dougan G, Walker MJ.

Nat Genet. 2019 Jun;51(6):1035-1043. doi: 10.1038/s41588-019-0417-8. Epub 2019 May 27. Erratum in: Nat Genet. 2019 Jul 19;:.


Potential for Molecular Testing for Group A Streptococcus to Improve Diagnosis and Management in a High-Risk Population: A Prospective Study.

Ralph AP, Holt DC, Islam S, Osowicki J, Carroll DE, Tong SYC, Bowen AC.

Open Forum Infect Dis. 2019 Feb 26;6(4):ofz097. doi: 10.1093/ofid/ofz097. eCollection 2019 Apr.


Mycobacterial mimicry in a man from Myanmar.

Griffin DW, Huang GKL, Lachapelle P, Tong SY, Mahanty S.

Med J Aust. 2019 May;210(8):349-351.e1. doi: 10.5694/mja2.50133. Epub 2019 Apr 9. No abstract available.


A Survey of Infectious Diseases and Microbiology Clinicians in Australia and New Zealand About the Management of Staphylococcus aureus Bacteremia.

Tong SYC, Campbell A, Bowen AC, Davis JS.

Clin Infect Dis. 2019 Oct 30;69(10):1835-1836. doi: 10.1093/cid/ciz275. No abstract available.


Systematic Review of Group A Streptococcal emm Types Associated with Acute Post-Streptococcal Glomerulonephritis.

Worthing KA, Lacey JA, Price DJ, McIntyre L, Steer AC, Tong SYC, Davies MR.

Am J Trop Med Hyg. 2019 May;100(5):1066-1070. doi: 10.4269/ajtmh.18-0827.


Burden of skin disease in two remote primary healthcare centres in northern and central Australia.

Thomas L, Bowen AC, Ly M, Connors C, Andrews R, Tong SYC.

Intern Med J. 2019 Mar;49(3):396-399. doi: 10.1111/imj.14222.


Tracing Ancient Human Migrations into Sahul Using Hepatitis B Virus Genomes.

Yuen LKW, Littlejohn M, DuchĂȘne S, Edwards R, Bukulatjpi S, Binks P, Jackson K, Davies J, Davis JS, Tong SYC, Locarnini S.

Mol Biol Evol. 2019 May 1;36(5):942-954. doi: 10.1093/molbev/msz021.


The epidemiology of Staphylococcus aureus skin and soft tissue infection in the southern Barkly region of Australia's Northern Territory in 2017.

Davey RX, Tong SYC.

Pathology. 2019 Apr;51(3):308-312. doi: 10.1016/j.pathol.2018.11.010. Epub 2019 Feb 25.


Incidence of community onset MRSA in Australia: least reported where it is Most prevalent.

Cameron JK, Hall L, Tong SYC, Paterson DL, Halton K.

Antimicrob Resist Infect Control. 2019 Feb 12;8:33. doi: 10.1186/s13756-019-0485-7. eCollection 2019.


High burden of infectious disease and antibiotic use in early life in Australian Aboriginal communities.

Cuningham W, McVernon J, Lydeamore MJ, Andrews RM, Carapetis J, Kearns T, Clucas D, Dhurrkay RG, Tong SYC, Campbell PT.

Aust N Z J Public Health. 2019 Apr;43(2):149-155. doi: 10.1111/1753-6405.12876. Epub 2019 Feb 6.


In Vitro and In Vivo Analysis of the Effects of 3,5-DMA and Its Metabolites in Neural Oxidative Stress and Neurodevelopmental Toxicity.

Chao MW, Kuo HC, Tong SY, Yang YS, Chuang YC, Tseng CY.

Toxicol Sci. 2019 Apr 1;168(2):405-419. doi: 10.1093/toxsci/kfy306.


Treatment, prevention and public health management of impetigo, scabies, crusted scabies and fungal skin infections in endemic populations: a systematic review.

May PJ, Tong SYC, Steer AC, Currie BJ, Andrews RM, Carapetis JR, Bowen AC.

Trop Med Int Health. 2019 Mar;24(3):280-293. doi: 10.1111/tmi.13198. Epub 2019 Jan 28.


Benefit of Echocardiography in Patients With Staphylococcus aureus Bacteremia at Low Risk of Endocarditis.

Heriot GS, Tong SYC, Cheng AC, Liew D.

Open Forum Infect Dis. 2018 Dec 11;5(12):ofy303. doi: 10.1093/ofid/ofy303. eCollection 2018 Dec.


Good Studies Evaluate the Disease While Great Studies Evaluate the Patient: Development and Application of a Desirability of Outcome Ranking Endpoint for Staphylococcus aureus Bloodstream Infection.

Doernberg SB, Tran TTT, Tong SYC, Paul M, Yahav D, Davis JS, Leibovici L, Boucher HW, Corey GR, Cosgrove SE, Chambers HF, Fowler VG, Evans SR, Holland TL; Antibacterial Resistance Leadership Group.

Clin Infect Dis. 2019 May 2;68(10):1691-1698. doi: 10.1093/cid/ciy766.


Adjunctive protein synthesis inhibitor antibiotics for toxin suppression in Staphylococcus aureus infections: a systematic appraisal.

Campbell AJ, Dotel R, Blyth CC, Davis JS, Tong SYC, Bowen AC.

J Antimicrob Chemother. 2019 Jan 1;74(1):1-5. doi: 10.1093/jac/dky387.


A biological model of scabies infection dynamics and treatment informs mass drug administration strategies to increase the likelihood of elimination.

Lydeamore MJ, Campbell PT, Regan DG, Tong SYC, Andrews RM, Steer AC, Romani L, Kaldor JM, McVernon J, McCaw JM.

Math Biosci. 2019 Mar;309:163-173. doi: 10.1016/j.mbs.2018.08.007. Epub 2018 Aug 24.


Scabies and risk of skin sores in remote Australian Aboriginal communities: A self-controlled case series study.

Aung PTZ, Cuningham W, Hwang K, Andrews RM, Carapetis JR, Kearns T, Clucas D, McVernon J, Simpson JA, Tong SYC, Campbell PT.

PLoS Negl Trop Dis. 2018 Jul 25;12(7):e0006668. doi: 10.1371/journal.pntd.0006668. eCollection 2018 Jul.


Global Scale Dissemination of ST93: A Divergent Staphylococcus aureus Epidemic Lineage That Has Recently Emerged From Remote Northern Australia.

van Hal SJ, Steinig EJ, Andersson P, Holden MTG, Harris SR, Nimmo GR, Williamson DA, Heffernan H, Ritchie SR, Kearns AM, Ellington MJ, Dickson E, de Lencastre H, Coombs GW, Bentley SD, Parkhill J, Holt DC, Giffard PM, Tong SYC.

Front Microbiol. 2018 Jul 9;9:1453. doi: 10.3389/fmicb.2018.01453. eCollection 2018.


Gene exchange drives the ecological success of a multi-host bacterial pathogen.

Richardson EJ, Bacigalupe R, Harrison EM, Weinert LA, Lycett S, Vrieling M, Robb K, Hoskisson PA, Holden MTG, Feil EJ, Paterson GK, Tong SYC, Shittu A, van Wamel W, Aanensen DM, Parkhill J, Peacock SJ, Corander J, Holmes M, Fitzgerald JR.

Nat Ecol Evol. 2018 Sep;2(9):1468-1478. doi: 10.1038/s41559-018-0617-0. Epub 2018 Jul 23.


Cross-link regulation of precursor N-cadherin and FGFR1 by GDNF increases U251MG cell viability.

Tang CX, Gu YX, Liu XF, Tong SY, Ayanlaja AA, Gao Y, Ji GQ, Xiong Y, Huang LY, Gao DS.

Oncol Rep. 2018 Jul;40(1):443-453. doi: 10.3892/or.2018.6405. Epub 2018 Apr 30.


Sub-optimal protection against past hepatitis B virus infection where subtype mismatch exists between vaccine and circulating viral genotype in northern Australia.

Cheah BC, Davies J, Singh GR, Wood N, Jackson K, Littlejohn M, Davison B, McIntyre P, Locarnini S, Davis JS, Tong SYC.

Vaccine. 2018 Jun 7;36(24):3533-3540. doi: 10.1016/j.vaccine.2018.01.062. Epub 2018 May 4.


Calculation of the age of the first infection for skin sores and scabies in five remote communities in northern Australia.

Lydeamore MJ, Campbell PT, Cuningham W, Andrews RM, Kearns T, Clucas D, Gundjirryirr Dhurrkay R, Carapetis J, Tong SYC, McCaw JM, McVernon J.

Epidemiol Infect. 2018 Jul;146(9):1194-1201. doi: 10.1017/S0950268818001061. Epub 2018 May 8.


Investigation of trimethoprim/sulfamethoxazole resistance in an emerging sequence type 5 methicillin-resistant Staphylococcus aureus clone reveals discrepant resistance reporting.

Harris TM, Bowen AC, Holt DC, Sarovich DS, Stevens K, Currie BJ, Howden BP, Carapetis JR, Giffard PM, Tong SYC.

Clin Microbiol Infect. 2018 Sep;24(9):1027-1029. doi: 10.1016/j.cmi.2018.04.020. Epub 2018 May 1. No abstract available.


Streptococcus gallolyticus subsp. pasteurianus meningitis complicated by venous sinus thrombosis: A case report.

Wardle M, Mu A, Tong SYC.

Int J Infect Dis. 2018 Jun;71:30-32. doi: 10.1016/j.ijid.2018.04.005. Epub 2018 Apr 12.


The unique aspects of chronic hepatitis B infection in Aboriginal and Torres Strait Islander people.

Davies J, Boutlis CS, Marshall CS, Tong SYC, Davis JS.

Intern Med J. 2018 Apr;48(4):484-485. doi: 10.1111/imj.13759. No abstract available.


Pt-like Hydrogen Evolution Electrocatalysis on PANI/CoP Hybrid Nanowires by Weakening the Shackles of Hydrogen Ions on the Surfaces of Catalysts.

Feng JX, Tong SY, Tong YX, Li GR.

J Am Chem Soc. 2018 Apr 18;140(15):5118-5126. doi: 10.1021/jacs.7b12968. Epub 2018 Apr 9. Erratum in: J Am Chem Soc. 2019 Aug 28;141(34):13698.


What risk of endocarditis is low enough to justify the omission of transoesophageal echocardiography in Staphylococcus aureus bacteraemia? A narrative review.

Heriot GS, Tong SYC, Cheng AC, Liew D.

Clin Microbiol Infect. 2018 Dec;24(12):1251-1256. doi: 10.1016/j.cmi.2018.03.027. Epub 2018 Mar 23. Review.


Implications of asymptomatic carriers for infectious disease transmission and control.

Chisholm RH, Campbell PT, Wu Y, Tong SYC, McVernon J, Geard N.

R Soc Open Sci. 2018 Feb 14;5(2):172341. doi: 10.1098/rsos.172341. eCollection 2018 Feb.


Immortal Time Bias in Assessing Evidence-Based Care Processes for Staphylococcus aureus Bacteremia.

Tong SYC, Cheng AC, Denholm JT.

JAMA Intern Med. 2018 Feb 1;178(2):295-296. doi: 10.1001/jamainternmed.2017.7947. No abstract available.


Clinical variation in the use of echocardiography in Staphylococcus aureus bacteraemia: a multi-centre cohort study.

Heriot GS, Tong SYC, Cheng AC, Thevarajan I, Levinson MR, Visvanathan K, Liew D.

Eur J Clin Microbiol Infect Dis. 2018 Mar;37(3):469-474. doi: 10.1007/s10096-018-3192-z. Epub 2018 Jan 22.


Criteria for Identifying Patients With Staphylococcus aureus Bacteremia Who Are at Low Risk of Endocarditis: A Systematic Review.

Heriot GS, Cronin K, Tong SYC, Cheng AC, Liew D.

Open Forum Infect Dis. 2017 Nov 24;4(4):ofx261. doi: 10.1093/ofid/ofx261. eCollection 2017 Fall. Review.


Antimicrobial resistance in urine and skin isolates in Timor-Leste.

Marr I, Sarmento N, O'Brien M, Lee K, Gusmao C, de Castro G, Janson S, Tong SYC, Baird RW, Francis JR.

J Glob Antimicrob Resist. 2018 Jun;13:135-138. doi: 10.1016/j.jgar.2017.12.010. Epub 2017 Dec 23.


Sulfamethoxazole-Trimethoprim (Cotrimoxazole) for Skin and Soft Tissue Infections Including Impetigo, Cellulitis, and Abscess.

Bowen AC, Carapetis JR, Currie BJ, Fowler V Jr, Chambers HF, Tong SYC.

Open Forum Infect Dis. 2017 Nov 2;4(4):ofx232. doi: 10.1093/ofid/ofx232. eCollection 2017 Fall. Review.


Prolonged Detection of Japanese Encephalitis Virus in Urine and Whole Blood in a Returned Short-term Traveler.

Huang GKL, Tio SY, Caly L, Nicholson S, Thevarajan I, Papadakis G, Catton M, Tong SYC, Druce J.

Open Forum Infect Dis. 2017 Sep 27;4(4):ofx203. doi: 10.1093/ofid/ofx203. eCollection 2017 Fall.

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