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[Effects of land use change on soil organic carbon and total nitrogen storage in Karst immigration regions of Guangxi Province, China.]

Tong JH, Hu YC, Du ZL, Zuo YQ, Li YY.

Ying Yong Sheng Tai Xue Bao. 2018 Sep;29(9):2890-2896. doi: 10.13287/j.1001-9332.201809.019. Chinese.


EXOSC4 functions as a potential oncogene in development and progression of colorectal cancer.

Pan Y, Tong JHM, Kang W, Lung RWM, Chak WP, Chung LY, Wu F, Li H, Yu J, Chan AWH, To KF.

Mol Carcinog. 2018 Dec;57(12):1780-1791. doi: 10.1002/mc.22896. Epub 2018 Sep 21.


The Clinical Value of PELP1 for Breast Cancer: A Comparison with Multiple Cancers and Analysis in Breast Cancer Subtypes.

Wang X, Tsang JYS, Lee MA, Ni YB, Tong JH, Chan SK, Cheung SY, To KF, Tse GM.

Cancer Res Treat. 2018 Aug 23. doi: 10.4143/crt.2018.316. [Epub ahead of print]


RASAL2 promotes tumor progression through LATS2/YAP1 axis of hippo signaling pathway in colorectal cancer.

Pan Y, Tong JHM, Lung RWM, Kang W, Kwan JSH, Chak WP, Tin KY, Chung LY, Wu F, Ng SSM, Mak TWC, Yu J, Lo KW, Chan AWH, To KF.

Mol Cancer. 2018 Jul 23;17(1):102. doi: 10.1186/s12943-018-0853-6.


Loss of tumor suppressor IGFBP4 drives epigenetic reprogramming in hepatic carcinogenesis.

Lee YY, Mok MT, Kang W, Yang W, Tang W, Wu F, Xu L, Yan M, Yu Z, Lee SD, Tong JHM, Cheung YS, Lai PBS, Yu DY, Wang Q, Wong GLH, Chan AM, Yip KY, To KF, Cheng ASL.

Nucleic Acids Res. 2018 Sep 28;46(17):8832-8847. doi: 10.1093/nar/gky589.


Granulin epithelin precursor promotes colorectal carcinogenesis by activating MARK/ERK pathway.

Pan Y, Cheung ST, Tong JHM, Tin KY, Kang W, Lung RWM, Wu F, Li H, Ng SSM, Mak TWC, To KF, Chan AWH.

J Transl Med. 2018 Jun 4;16(1):150. doi: 10.1186/s12967-018-1530-7.


Assessment of programmed cell death ligand-1 expression by 4 diagnostic assays and its clinicopathological correlation in a large cohort of surgical resected non-small cell lung carcinoma.

Chan AWH, Tong JHM, Kwan JSH, Chow C, Chung LY, Chau SL, Lung RWM, Ng CSH, Wan IYP, Mok TSK, To KF.

Mod Pathol. 2018 Sep;31(9):1381-1390. doi: 10.1038/s41379-018-0053-3. Epub 2018 Apr 30.


The role of human papillomavirus in laryngeal cancer in Southern China.

Lam EWH, Chan MMH, Wai CKC, Ngai CM, Chen Z, Wong MCS, Yeung ACM, Tong JHM, Chan ABW, To KF, Chan PKS.

J Med Virol. 2018 Jun;90(6):1150-1159. doi: 10.1002/jmv.25058. Epub 2018 Mar 6.


miR-375 is involved in Hippo pathway by targeting YAP1/TEAD4-CTGF axis in gastric carcinogenesis.

Kang W, Huang T, Zhou Y, Zhang J, Lung RWM, Tong JHM, Chan AWH, Zhang B, Wong CC, Wu F, Dong Y, Wang S, Yang W, Pan Y, Chak WP, Cheung AHK, Pang JCS, Yu J, Cheng ASL, To KF.

Cell Death Dis. 2018 Jan 24;9(2):92. doi: 10.1038/s41419-017-0134-0.


Increased expression of GATA zinc finger domain containing 1 through gene amplification promotes liver cancer by directly inducing phosphatase of regenerating liver 3.

Sun W, Zhang Y, Wong KC, Liu K, Yang Y, Wu B, Tong JHM, Chan AWH, Chan HLY, Yu J.

Hepatology. 2018 Jun;67(6):2302-2319. doi: 10.1002/hep.29750. Epub 2018 Mar 23.


EBV-encoded miRNAs target ATM-mediated response in nasopharyngeal carcinoma.

Lung RW, Hau PM, Yu KH, Yip KY, Tong JH, Chak WP, Chan AW, Lam KH, Lo AK, Tin EK, Chau SL, Pang JC, Kwan JS, Busson P, Young LS, Yap LF, Tsao SW, To KF, Lo KW.

J Pathol. 2018 Apr;244(4):394-407. doi: 10.1002/path.5018. Epub 2018 Feb 16.


Hepatoma-intrinsic CCRK inhibition diminishes myeloid-derived suppressor cell immunosuppression and enhances immune-checkpoint blockade efficacy.

Zhou J, Liu M, Sun H, Feng Y, Xu L, Chan AWH, Tong JH, Wong J, Chong CCN, Lai PBS, Wang HK, Tsang SW, Goodwin T, Liu R, Huang L, Chen Z, Sung JJ, Chow KL, To KF, Cheng AS.

Gut. 2018 May;67(5):931-944. doi: 10.1136/gutjnl-2017-314032. Epub 2017 Sep 22.


TEAD1/4 exerts oncogenic role and is negatively regulated by miR-4269 in gastric tumorigenesis.

Zhou Y, Huang T, Zhang J, Wong CC, Zhang B, Dong Y, Wu F, Tong JHM, Wu WKK, Cheng ASL, Yu J, Kang W, To KF.

Oncogene. 2017 Nov 23;36(47):6518-6530. doi: 10.1038/onc.2017.257. Epub 2017 Jul 31.


[Effects of Quercetin on Chronic Myeloid Leukemia Cell Line Resistant to Imatinib and Its Mechanism].

Lu HY, Chen J, DU SH, Jia PM, Tong JH, Wu YL, Zhou L.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2017 Apr;25(2):346-352. doi: 10.7534/j.issn.1009-2137.2017.02.007. Chinese.


Sertraline exerts its antitumor functions through both apoptosis and autophagy pathways in acute myeloid leukemia cells.

Xia D, Zhang YT, Xu GP, Yan WW, Pan XR, Tong JH.

Leuk Lymphoma. 2017 Sep;58(9):1-10. doi: 10.1080/10428194.2017.1287358. Epub 2017 Feb 13.


Allelic variation in dopamine D2 receptor gene is associated with attentional impulsiveness on the Barratt Impulsiveness Scale (BIS-11).

Taylor JB, Cummins TDR, Fox AM, Johnson BP, Tong JH, Visser TAW, Hawi Z, Bellgrove MA.

World J Biol Psychiatry. 2017 Jan 20:1-9. doi: 10.1080/15622975.2016.1273549. [Epub ahead of print]


The effects of muscle weakness on degenerative spondylolisthesis: A finite element study.

Zhu R, Niu WX, Zeng ZL, Tong JH, Zhen ZW, Zhou S, Yu Y, Cheng LM.

Clin Biomech (Bristol, Avon). 2017 Jan;41:34-38. doi: 10.1016/j.clinbiomech.2016.11.007. Epub 2016 Nov 26.


Downregulation of long non-coding RNA MEG3 in nasopharyngeal carcinoma.

Chak WP, Lung RW, Tong JH, Chan SY, Lun SW, Tsao SW, Lo KW, To KF.

Mol Carcinog. 2017 Mar;56(3):1041-1054. doi: 10.1002/mc.22569. Epub 2016 Oct 20.


Separating the wheat from the chaff: systematic identification of functionally relevant noncoding variants in ADHD.

Tong JH, Hawi Z, Dark C, Cummins TD, Johnson BP, Newman DP, Lau R, Vance A, Heussler HS, Matthews N, Bellgrove MA, Pang KC.

Mol Psychiatry. 2016 Nov;21(11):1589-1598. doi: 10.1038/mp.2016.2. Epub 2016 Apr 26.


Dexmedetomidine regulate the malignancy of breast cancer cells by activating α2-adrenoceptor/ERK signaling pathway.

Xia M, Ji NN, Duan ML, Tong JH, Xu JG, Zhang YM, Wang SH.

Eur Rev Med Pharmacol Sci. 2016 Aug;20(16):3500-6.


EZH2 coupled with HOTAIR to silence MicroRNA-34a by the induction of heterochromatin formation in human pancreatic ductal adenocarcinoma.

Li CH, Xiao Z, Tong JH, To KF, Fang X, Cheng AS, Chen Y.

Int J Cancer. 2017 Jan 1;140(1):120-129. doi: 10.1002/ijc.30414. Epub 2016 Sep 19.


Concurrent fatty liver increases risk of hepatocellular carcinoma among patients with chronic hepatitis B.

Chan AW, Wong GL, Chan HY, Tong JH, Yu YH, Choi PC, Chan HL, To KF, Wong VW.

J Gastroenterol Hepatol. 2017 Mar;32(3):667-676. doi: 10.1111/jgh.13536.


SLC25A22 Promotes Proliferation and Survival of Colorectal Cancer Cells With KRAS Mutations and Xenograft Tumor Progression in Mice via Intracellular Synthesis of Aspartate.

Wong CC, Qian Y, Li X, Xu J, Kang W, Tong JH, To KF, Jin Y, Li W, Chen H, Go MY, Wu JL, Cheng KW, Ng SS, Sung JJ, Cai Z, Yu J.

Gastroenterology. 2016 Nov;151(5):945-960.e6. doi: 10.1053/j.gastro.2016.07.011. Epub 2016 Jul 21.


MET DNA Alterations in NSCLC-Reply.

Tong JH, Chan AW, To KF.

Clin Cancer Res. 2016 Jul 15;22(14):3699. doi: 10.1158/1078-0432.CCR-16-1042. No abstract available.


Tramadol regulates proliferation, migration and invasion via PTEN/PI3K/AKT signaling in lung adenocarcinoma cells.

Xia M, Tong JH, Ji NN, Duan ML, Tan YH, Xu JG.

Eur Rev Med Pharmacol Sci. 2016 Jun;20(12):2573-80.


Steatotic hepatocellular carcinoma: a variant associated with metabolic factors and late tumour relapse.

Chan AW, Yu S, Yu YH, Tong JH, Wang L, Tin EK, Chong CC, Chan SL, Wong GL, Wong VW, Chan HL, Lai PB, To KF.

Histopathology. 2016 Dec;69(6):971-984. doi: 10.1111/his.13029. Epub 2016 Sep 9.


Dysregulated expression of arginine metabolic enzymes in human intestinal tissues of necrotizing enterocolitis and response of CaCO2 cells to bacterial components.

Leung KT, Chan KY, Ma TP, Yu JW, Tong JH, Tam YH, Cheung HM, To KF, Lam HS, Lee KH, Li K, Ng PC.

J Nutr Biochem. 2016 Mar;29:64-72. doi: 10.1016/j.jnutbio.2015.10.010. Epub 2015 Nov 2.


MET Amplification and Exon 14 Splice Site Mutation Define Unique Molecular Subgroups of Non-Small Cell Lung Carcinoma with Poor Prognosis.

Tong JH, Yeung SF, Chan AW, Chung LY, Chau SL, Lung RW, Tong CY, Chow C, Tin EK, Yu YH, Li H, Pan Y, Chak WP, Ng CS, Mok TS, To KF.

Clin Cancer Res. 2016 Jun 15;22(12):3048-56. doi: 10.1158/1078-0432.CCR-15-2061. Epub 2016 Feb 4.


Tramadol inhibits proliferation, migration and invasion via α2-adrenoceptor signaling in breast cancer cells.

Xia M, Tong JH, Zhou ZQ, Duan ML, Xu JG, Zeng HJ, Wang SH.

Eur Rev Med Pharmacol Sci. 2016;20(1):157-65.


miR-508-3p concordantly silences NFKB1 and RELA to inactivate canonical NF-κB signaling in gastric carcinogenesis.

Huang T, Kang W, Zhang B, Wu F, Dong Y, Tong JH, Yang W, Zhou Y, Zhang L, Cheng AS, Yu J, To KF.

Mol Cancer. 2016 Jan 22;15:9. doi: 10.1186/s12943-016-0493-7.


Yin Yang 1-mediated epigenetic silencing of tumour-suppressive microRNAs activates nuclear factor-κB in hepatocellular carcinoma.

Tsang DP, Wu WK, Kang W, Lee YY, Wu F, Yu Z, Xiong L, Chan AW, Tong JH, Yang W, Li MS, Lau SS, Li X, Lee SD, Yang Y, Lai PB, Yu DY, Xu G, Lo KW, Chan MT, Wang H, Lee TL, Yu J, Wong N, Yip KY, To KF, Cheng AS.

J Pathol. 2016 Apr;238(5):651-64. doi: 10.1002/path.4688.


MiR-26b suppresses tumor cell proliferation, migration and invasion by directly targeting COX-2 in lung cancer.

Xia M, Duan ML, Tong JH, Xu JG.

Eur Rev Med Pharmacol Sci. 2015 Dec;19(24):4728-37.


RIG-G inhibits the proliferation of NB4 cells and propels ATRA-induced differentiation of APL cells.

Lou YJ, Pan XR, Jia PM, Jin J, Tong JH.

Leuk Res. 2016 Jan;40:83-9. doi: 10.1016/j.leukres.2015.11.007. Epub 2015 Nov 21.


Erythropoietin Pretreatment Attenuates Seawater Aspiration-Induced Acute Lung Injury in Rats.

Ji MH, Tong JH, Tan YH, Cao ZY, Ou CY, Li WY, Yang JJ, Peng YG, Zhu SH.

Inflammation. 2016 Feb;39(1):447-456. doi: 10.1007/s10753-015-0268-0.


Histone Deacetylase HDAC8 Promotes Insulin Resistance and β-Catenin Activation in NAFLD-Associated Hepatocellular Carcinoma.

Tian Y, Wong VW, Wong GL, Yang W, Sun H, Shen J, Tong JH, Go MY, Cheung YS, Lai PB, Zhou M, Xu G, Huang TH, Yu J, To KF, Cheng AS, Chan HL.

Cancer Res. 2015 Nov 15;75(22):4803-16. doi: 10.1158/0008-5472.CAN-14-3786. Epub 2015 Sep 17.


[Experimental Study on Apoptosis of Kasumi-1 Cells Induced by Sertraline and Its Molecular Mechanism].

Yan WW, Xia D, Zhang YT, Pan XR, Tong JH.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2015 Aug;23(4):966-70. doi: 10.7534/j.issn.1009-2137.2015.04.011. Chinese.


Profiling of Oncogenic Driver Events in Lung Adenocarcinoma Revealed MET Mutation as Independent Prognostic Factor.

Yeung SF, Tong JHM, Law PPW, Chung LY, Lung RWM, Tong CYK, Chow C, Chan AWH, Wan IYP, Mok TSK, To KF.

J Thorac Oncol. 2015 Sep;10(9):1292-1300. doi: 10.1097/JTO.0000000000000620.


Phase I/II study of temsirolimus for patients with unresectable Hepatocellular Carcinoma (HCC)- a correlative study to explore potential biomarkers for response.

Yeo W, Chan SL, Mo FK, Chu CM, Hui JW, Tong JH, Chan AW, Koh J, Hui EP, Loong H, Lee K, Li L, Ma B, To KF, Yu SC.

BMC Cancer. 2015 May 12;15:395. doi: 10.1186/s12885-015-1334-6.


Systemic Lipopolysaccharide Administration-Induced Cognitive Impairments are Reversed by Erythropoietin Treatment in Mice.

Gao R, Tang YH, Tong JH, Yang JJ, Ji MH, Zhu SH.

Inflammation. 2015 Oct;38(5):1949-58. doi: 10.1007/s10753-015-0175-4.


Elucidating the prognostic significance of KRAS, NRAS, BRAF and PIK3CA mutations in Chinese patients with metastatic colorectal cancer.

Ma BB, Mo F, Tong JH, Wong A, Wong SC, Ho WM, Wu C, Lam PW, Chan KF, Chan TS, Tsui WM, Tsang AK, Fung MN, Chan AT, To KF.

Asia Pac J Clin Oncol. 2015 Jun;11(2):160-9. doi: 10.1111/ajco.12342. Epub 2015 Apr 13.


Targeting of YAP1 by microRNA-15a and microRNA-16-1 exerts tumor suppressor function in gastric adenocarcinoma.

Kang W, Tong JH, Lung RW, Dong Y, Zhao J, Liang Q, Zhang L, Pan Y, Yang W, Pang JC, Cheng AS, Yu J, To KF.

Mol Cancer. 2015 Feb 22;14:52. doi: 10.1186/s12943-015-0323-3.


Lymphoepithelioma-like hepatocellular carcinoma: an uncommon variant of hepatocellular carcinoma with favorable outcome.

Chan AW, Tong JH, Pan Y, Chan SL, Wong GL, Wong VW, Lai PB, To KF.

Am J Surg Pathol. 2015 Mar;39(3):304-12. doi: 10.1097/PAS.0000000000000376.


An association between a dopamine transporter gene (SLC6A3) haplotype and ADHD symptom measures in nonclinical adults.

Tong JH, Cummins TD, Johnson BP, McKinley LA, Pickering HE, Fanning P, Stefanac NR, Newman DP, Hawi Z, Bellgrove MA.

Am J Med Genet B Neuropsychiatr Genet. 2015 Mar;168B(2):89-96. doi: 10.1002/ajmg.b.32283. Epub 2015 Feb 5.


Helicobacter pylori-induced STAT3 activation and signalling network in gastric cancer.

Zhao J, Dong Y, Kang W, Go MY, Tong JH, Ng EK, Chiu PW, Cheng AS, To KF, Sung JJ, Yu J.

Oncoscience. 2014 Jul 3;1(6):468-475. eCollection 2014.


[Pharmacodynamic differences between hangmaidong and chuanmaidong based on metabonomics].

Tong JH, Wang YX, Sun H, Liao N, Li XE, Qin MJ, Pang XC.

Yao Xue Xue Bao. 2014 Oct;49(10):1451-6. Chinese.


Epigenetic silencing of miR-490-3p reactivates the chromatin remodeler SMARCD1 to promote Helicobacter pylori-induced gastric carcinogenesis.

Shen J, Xiao Z, Wu WK, Wang MH, To KF, Chen Y, Yang W, Li MS, Shin VY, Tong JH, Kang W, Zhang L, Li M, Wang L, Lu L, Chan RL, Wong SH, Yu J, Chan MT, Chan FK, Sung JJ, Cheng AS, Cho CH.

Cancer Res. 2015 Feb 15;75(4):754-65. doi: 10.1158/0008-5472.CAN-14-1301. Epub 2014 Dec 12.


Dopamine transporter genotype is associated with a lateralized resistance to distraction during attention selection.

Newman DP, Cummins TD, Tong JH, Johnson BP, Pickering H, Fanning P, Wagner J, Goodrich JT, Hawi Z, Chambers CD, Bellgrove MA.

J Neurosci. 2014 Nov 19;34(47):15743-50. doi: 10.1523/JNEUROSCI.2327-14.2014.


Germline TP53 mutations is common in patients with two early-onset primary malignancies.

Chak BP, Chan ES, Tong JH, Leung AW, Cheng FW, Lam GK, Shing MM, Li CK, To KF.

Clin Genet. 2015 May;87(5):499-501. doi: 10.1111/cge.12480. Epub 2014 Oct 8. No abstract available.


let-7b/g silencing activates AKT signaling to promote gastric carcinogenesis.

Kang W, Tong JH, Lung RW, Dong Y, Yang W, Pan Y, Lau KM, Yu J, Cheng AS, To KF.

J Transl Med. 2014 Oct 5;12:281. doi: 10.1186/s12967-014-0281-3.


Novel recurrently mutated genes and a prognostic mutation signature in colorectal cancer.

Yu J, Wu WK, Li X, He J, Li XX, Ng SS, Yu C, Gao Z, Yang J, Li M, Wang Q, Liang Q, Pan Y, Tong JH, To KF, Wong N, Zhang N, Chen J, Lu Y, Lai PB, Chan FK, Li Y, Kung HF, Yang H, Wang J, Sung JJ.

Gut. 2015 Apr;64(4):636-45. doi: 10.1136/gutjnl-2013-306620. Epub 2014 Jun 20.

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