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Items: 1 to 50 of 476

1.

Pathology in Irish medical education.

Humphreys H, Stevens N, Leddin D, Callagy G, Burke L, Watson RW, Toner M.

J Clin Pathol. 2019 Aug 22. pii: jclinpath-2019-206033. doi: 10.1136/jclinpath-2019-206033. [Epub ahead of print]

PMID:
31439711
2.

Blood-based monitoring identifies acquired and targetable driver HER2 mutations in endocrine-resistant metastatic breast cancer.

Medford AJ, Dubash TD, Juric D, Spring L, Niemierko A, Vidula N, Peppercorn J, Isakoff S, Reeves BA, LiCausi JA, Wesley B, Malvarosa G, Yuen M, Wittner BS, Lawrence MS, Iafrate AJ, Ellisen L, Moy B, Toner M, Maheswaran S, Haber DA, Bardia A.

NPJ Precis Oncol. 2019 Jul 16;3:18. doi: 10.1038/s41698-019-0090-5. eCollection 2019.

3.

Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping.

Severe N, Karabacak NM, Gustafsson K, Baryawno N, Courties G, Kfoury Y, Kokkaliaris KD, Rhee C, Lee D, Scadden EW, Garcia-Robledo JE, Brouse T, Nahrendorf M, Toner M, Scadden DT.

Cell Stem Cell. 2019 Jun 26. pii: S1934-5909(19)30267-X. doi: 10.1016/j.stem.2019.06.003. [Epub ahead of print]

PMID:
31279774
4.

Preface to the Interfaces and Biology 1: Cryobiology Special Issue.

Elliott JAW, Toner M.

Langmuir. 2019 Jun 11;35(23):7335-7336. doi: 10.1021/acs.langmuir.9b01226. No abstract available.

PMID:
31181915
5.

COX-2 mediates tumor-stromal prolactin signaling to initiate tumorigenesis.

Zheng Y, Comaills V, Burr R, Boulay G, Miyamoto DT, Wittner BS, Emmons E, Sil S, Koulopoulos MW, Broderick KT, Tai E, Rengarajan S, Kulkarni AS, Shioda T, Wu CL, Ramaswamy S, Ting DT, Toner M, Rivera MN, Maheswaran S, Haber DA.

Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5223-5232. doi: 10.1073/pnas.1819303116. Epub 2019 Feb 28.

6.

Rapid Isolation and Concentration of Pathogenic Fungi Using Inertial Focusing on a Chip-Based Platform.

Fuchs BB, Eatemadpour S, Martel-Foley JM, Stott S, Toner M, Mylonakis E.

Front Cell Infect Microbiol. 2019 Feb 12;9:27. doi: 10.3389/fcimb.2019.00027. eCollection 2019.

7.

Liquid biopsy: a perspective for probing blood for cancer.

Jeffrey SS, Toner M.

Lab Chip. 2019 Feb 12;19(4):548-549. doi: 10.1039/c8lc90117a. No abstract available.

PMID:
30688954
8.

Exploring Dynamics and Structure of Biomolecules, Cryoprotectants, and Water Using Molecular Dynamics Simulations: Implications for Biostabilization and Biopreservation.

Weng L, Stott SL, Toner M.

Annu Rev Biomed Eng. 2019 Jun 4;21:1-31. doi: 10.1146/annurev-bioeng-060418-052130. Epub 2018 Dec 10.

PMID:
30525930
9.

Bulk Droplet Vitrification: An Approach to Improve Large-Scale Hepatocyte Cryopreservation Outcome.

de Vries RJ, Banik PD, Nagpal S, Weng L, Ozer S, van Gulik TM, Toner M, Tessier SN, Uygun K.

Langmuir. 2019 Jun 11;35(23):7354-7363. doi: 10.1021/acs.langmuir.8b02831. Epub 2019 Jan 9.

PMID:
30514081
10.

Data Set for the Reporting of Carcinomas of the Nasal Cavity and Paranasal Sinuses: Explanations and Recommendations of the Guidelines From the International Collaboration on Cancer Reporting.

Franchi A, Bishop JA, Coleman H, Flucke U, Licitra LF, Pendás JLL, Stelow EB, Toner M, Weinreb I, Wenig BM, Thompson LDR.

Arch Pathol Lab Med. 2019 Apr;143(4):424-431. doi: 10.5858/arpa.2018-0404-SA. Epub 2018 Nov 30.

PMID:
30500298
11.

Immunofunctional photodegradable poly(ethylene glycol) hydrogel surfaces for the capture and release of rare cells.

LeValley PJ, Tibbitt MW, Noren B, Kharkar P, Kloxin AM, Anseth KS, Toner M, Oakey J.

Colloids Surf B Biointerfaces. 2019 Feb 1;174:483-492. doi: 10.1016/j.colsurfb.2018.11.049. Epub 2018 Nov 20.

PMID:
30497010
12.

On-chip oocyte denudation from cumulus-oocyte complexes for assisted reproductive therapy.

Weng L, Lee GY, Liu J, Kapur R, Toth TL, Toner M.

Lab Chip. 2018 Dec 4;18(24):3892-3902. doi: 10.1039/c8lc01075g.

PMID:
30465050
13.

Improved Detection of Circulating Epithelial Cells in Patients with Intraductal Papillary Mucinous Neoplasms.

Franses JW, Basar O, Kadayifci A, Yuksel O, Choz M, Kulkarni AS, Tai E, Vo KD, Arora KS, Desai N, Licausi JA, Toner M, Maheswaran S, Haber DA, Ryan DP, Brugge WR, Ting DT.

Oncologist. 2018 Oct;23(10):1260. doi: 10.1634/theoncologist.2017-0234erratum. No abstract available.

14.

Detection and Analysis of Circulating Epithelial Cells in Liquid Biopsies From Patients With Liver Disease.

Bhan I, Mosesso K, Goyal L, Philipp J, Kalinich M, Franses JW, Choz M, Oklu R, Toner M, Maheswaran S, Haber DA, Zhu AX, Chung RT, Aryee M, Ting DT.

Gastroenterology. 2018 Dec;155(6):2016-2018.e11. doi: 10.1053/j.gastro.2018.09.020. Epub 2018 Sep 13. No abstract available.

PMID:
30218669
15.

Role of synthetic antifreeze agents in catalyzing ice nucleation.

Weng L, Swei A, Toner M.

Cryobiology. 2018 Oct;84:91-94. doi: 10.1016/j.cryobiol.2018.08.010. Epub 2018 Aug 22.

PMID:
30144407
16.

A Digital RNA Signature of Circulating Tumor Cells Predicting Early Therapeutic Response in Localized and Metastatic Breast Cancer.

Kwan TT, Bardia A, Spring LM, Giobbie-Hurder A, Kalinich M, Dubash T, Sundaresan T, Hong X, LiCausi JA, Ho U, Silva EJ, Wittner BS, Sequist LV, Kapur R, Miyamoto DT, Toner M, Haber DA, Maheswaran S.

Cancer Discov. 2018 Oct;8(10):1286-1299. doi: 10.1158/2159-8290.CD-18-0432. Epub 2018 Aug 13.

PMID:
30104333
17.

Response to Letter to the Editor re 'Exploring the experiences and implementing strategies for physiotherapy students who perceive they have been bullied or harassed on clinical placements: participatory action research'.

Thomson D, Patterson D, Chapman H, Murray L, Toner M, Hassenkamp AM.

Physiotherapy. 2018 Sep;104(3):357. doi: 10.1016/j.physio.2017.07.002. Epub 2017 Jul 22. No abstract available.

PMID:
30072115
18.

Cryopreservation of infectious Cryptosporidium parvum oocysts.

Jaskiewicz JJ, Sandlin RD, Swei AA, Widmer G, Toner M, Tzipori S.

Nat Commun. 2018 Jul 23;9(1):2883. doi: 10.1038/s41467-018-05240-2.

19.

Janus-faced role of water in defining nanostructure of choline chloride/glycerol deep eutectic solvent.

Weng L, Toner M.

Phys Chem Chem Phys. 2018 Sep 12;20(35):22455-22462. doi: 10.1039/c8cp03882a.

PMID:
30024584
20.

Oscillatory inertial focusing in infinite microchannels.

Mutlu BR, Edd JF, Toner M.

Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):7682-7687. doi: 10.1073/pnas.1721420115. Epub 2018 Jul 10.

21.

Reclassification as NIFTP: a Retrospective Review in a Single Institution with an Emphasis on Workload.

O'Hare K, O'Regan E, Khattak A, Healy ML, Toner M.

Endocr Pathol. 2018 Sep;29(3):231-235. doi: 10.1007/s12022-018-9538-3.

PMID:
29978374
22.

Anti-thrombotic strategies for microfluidic blood processing.

Wong KHK, Edd JF, Tessier SN, Moyo WD, Mutlu BR, Bookstaver LD, Miller KL, Herrara S, Stott SL, Toner M.

Lab Chip. 2018 Jul 24;18(15):2146-2155. doi: 10.1039/c8lc00035b.

23.

Predictors of oropharyngeal cancer survival in Europe.

Anantharaman D, Billot A, Waterboer T, Gheit T, Abedi-Ardekani B, Lagiou P, Lagiou A, Ahrens W, Holcátová I, Merletti F, Kjaerheim K, Polesel J, Simonato L, Alemany L, Mena Cervigon M, Macfarlane TV, Znaor A, Thomson PJ, Robinson M, Canova C, Conway DI, Wright S, Healy CM, Toner ME, Pawlita M, Tommasino M, Brennan P.

Oral Oncol. 2018 Jun;81:89-94. doi: 10.1016/j.oraloncology.2018.04.016. Epub 2018 May 2.

24.

Genomic and Functional Fidelity of Small Cell Lung Cancer Patient-Derived Xenografts.

Drapkin BJ, George J, Christensen CL, Mino-Kenudson M, Dries R, Sundaresan T, Phat S, Myers DT, Zhong J, Igo P, Hazar-Rethinam MH, Licausi JA, Gomez-Caraballo M, Kem M, Jani KN, Azimi R, Abedpour N, Menon R, Lakis S, Heist RS, Büttner R, Haas S, Sequist LV, Shaw AT, Wong KK, Hata AN, Toner M, Maheswaran S, Haber DA, Peifer M, Dyson N, Thomas RK, Farago AF.

Cancer Discov. 2018 May;8(5):600-615. doi: 10.1158/2159-8290.CD-17-0935. Epub 2018 Feb 26.

25.

Ultra-fast vitrification of patient-derived circulating tumor cell lines.

Sandlin RD, Wong KHK, Tessier SN, Swei A, Bookstaver LD, Ahearn BE, Maheswaran S, Haber DA, Stott SL, Toner M.

PLoS One. 2018 Feb 23;13(2):e0192734. doi: 10.1371/journal.pone.0192734. eCollection 2018.

26.

AR Expression in Breast Cancer CTCs Associates with Bone Metastases.

Aceto N, Bardia A, Wittner BS, Donaldson MC, O'Keefe R, Engstrom A, Bersani F, Zheng Y, Comaills V, Niederhoffer K, Zhu H, Mackenzie O, Shioda T, Sgroi D, Kapur R, Ting DT, Moy B, Ramaswamy S, Toner M, Haber DA, Maheswaran S.

Mol Cancer Res. 2018 Apr;16(4):720-727. doi: 10.1158/1541-7786.MCR-17-0480. Epub 2018 Feb 16.

27.

Molecular signatures of circulating melanoma cells for monitoring early response to immune checkpoint therapy.

Hong X, Sullivan RJ, Kalinich M, Kwan TT, Giobbie-Hurder A, Pan S, LiCausi JA, Milner JD, Nieman LT, Wittner BS, Ho U, Chen T, Kapur R, Lawrence DP, Flaherty KT, Sequist LV, Ramaswamy S, Miyamoto DT, Lawrence M, Toner M, Isselbacher KJ, Maheswaran S, Haber DA.

Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):2467-2472. doi: 10.1073/pnas.1719264115. Epub 2018 Feb 16.

28.

The influence of smoking, age and stage at diagnosis on the survival after larynx, hypopharynx and oral cavity cancers in Europe: The ARCAGE study.

Abrahão R, Anantharaman D, Gaborieau V, Abedi-Ardekani B, Lagiou P, Lagiou A, Ahrens W, Holcatova I, Betka J, Merletti F, Richiardi L, Kjaerheim K, Serraino D, Polesel J, Simonato L, Alemany L, Agudo Trigueros A, Macfarlane TV, Macfarlane GJ, Znaor A, Robinson M, Canova C, Conway DI, Wright S, Healy CM, Toner M, Cadoni G, Boccia S, Gheit T, Tommasino M, Scelo G, Brennan P.

Int J Cancer. 2018 Jul 1;143(1):32-44. doi: 10.1002/ijc.31294. Epub 2018 Feb 23.

29.

Oral lymphangiectasias and Crohn's disease: two case reports.

Galvin S, Flint SR, Toner ME, Healy CM, Ekanayake K.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2018 Jul;126(1):e31-e34. doi: 10.1016/j.oooo.2017.12.014. Epub 2017 Dec 28.

PMID:
29397340
30.

Treatment Options for Amelobastic Carcinoma of the Mandible: A Case Series and Review of the Literature.

Sheridan GA, Nusrath MA, Toner M, Stassen LF.

Ir Med J. 2017 Oct 10;110(9):639. Review.

PMID:
29372954
31.

Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles.

Reátegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL.

Nat Commun. 2018 Jan 12;9(1):175. doi: 10.1038/s41467-017-02261-1.

32.

An RNA-Based Digital Circulating Tumor Cell Signature Is Predictive of Drug Response and Early Dissemination in Prostate Cancer.

Miyamoto DT, Lee RJ, Kalinich M, LiCausi JA, Zheng Y, Chen T, Milner JD, Emmons E, Ho U, Broderick K, Silva E, Javaid S, Kwan TT, Hong X, Dahl DM, McGovern FJ, Efstathiou JA, Smith MR, Sequist LV, Kapur R, Wu CL, Stott SL, Ting DT, Giobbie-Hurder A, Toner M, Maheswaran S, Haber DA.

Cancer Discov. 2018 Mar;8(3):288-303. doi: 10.1158/2159-8290.CD-16-1406. Epub 2018 Jan 4.

33.

Clusters of Circulating Tumor Cells: a Biophysical and Technological Perspective.

Au SH, Edd J, Haber DA, Maheswaran S, Stott SL, Toner M.

Curr Opin Biomed Eng. 2017 Sep;3:13-19. doi: 10.1016/j.cobme.2017.08.001. Epub 2017 Aug 10.

34.

Molecular Dynamics at the Interface between Ice and Poly(vinyl alcohol) and Ice Recrystallization Inhibition.

Weng L, Stott SL, Toner M.

Langmuir. 2018 May 1;34(17):5116-5123. doi: 10.1021/acs.langmuir.7b03243. Epub 2017 Dec 13.

PMID:
29199836
35.

Whole blood stabilization for the microfluidic isolation and molecular characterization of circulating tumor cells.

Wong KHK, Tessier SN, Miyamoto DT, Miller KL, Bookstaver LD, Carey TR, Stannard CJ, Thapar V, Tai EC, Vo KD, Emmons ES, Pleskow HM, Sandlin RD, Sequist LV, Ting DT, Haber DA, Maheswaran S, Stott SL, Toner M.

Nat Commun. 2017 Nov 23;8(1):1733. doi: 10.1038/s41467-017-01705-y.

36.

A highly-occupied, single-cell trapping microarray for determination of cell membrane permeability.

Weng L, Ellett F, Edd J, Wong KHK, Uygun K, Irimia D, Stott SL, Toner M.

Lab Chip. 2017 Nov 21;17(23):4077-4088. doi: 10.1039/c7lc00883j.

37.

Microfluidic isolation of platelet-covered circulating tumor cells.

Jiang X, Wong KHK, Khankhel AH, Zeinali M, Reategui E, Phillips MJ, Luo X, Aceto N, Fachin F, Hoang AN, Kim W, Jensen AE, Sequist LV, Maheswaran S, Haber DA, Stott SL, Toner M.

Lab Chip. 2017 Oct 11;17(20):3498-3503. doi: 10.1039/c7lc00654c.

38.

Monolithic Chip for High-throughput Blood Cell Depletion to Sort Rare Circulating Tumor Cells.

Fachin F, Spuhler P, Martel-Foley JM, Edd JF, Barber TA, Walsh J, Karabacak M, Pai V, Yu M, Smith K, Hwang H, Yang J, Shah S, Yarmush R, Sequist LV, Stott SL, Maheswaran S, Haber DA, Kapur R, Toner M.

Sci Rep. 2017 Sep 7;7(1):10936. doi: 10.1038/s41598-017-11119-x.

39.

Improved Detection of Circulating Epithelial Cells in Patients with Intraductal Papillary Mucinous Neoplasms.

Franses JW, Basar O, Kadayifci A, Yuksel O, Choz M, Kulkarni AS, Tai E, Vo KD, Arora KS, Desai N, Licausi JA, Toner M, Maheswaran S, Haber DA, Ryan DP, Brugge WR, Ting DT.

Oncologist. 2018 Jan;23(1):121-127. doi: 10.1634/theoncologist.2017-0234. Epub 2017 Aug 31. Erratum in: Oncologist. 2018 Oct;23(10):1260.

40.

Non-equilibrium Inertial Separation Array for High-throughput, Large-volume Blood Fractionation.

Mutlu BR, Smith KC, Edd JF, Nadar P, Dlamini M, Kapur R, Toner M.

Sci Rep. 2017 Aug 30;7(1):9915. doi: 10.1038/s41598-017-10295-0.

41.

Preservative solution that stabilizes erythrocyte morphology and leukocyte viability under ambient conditions.

Sandlin RD, Wong KHK, Boneschansker L, Carey TR, Miller KL, Rose G, Haber DA, Maheswaran S, Irimia D, Stott SL, Toner M.

Sci Rep. 2017 Jul 18;7(1):5658. doi: 10.1038/s41598-017-05978-7.

42.

The promise of organ and tissue preservation to transform medicine.

Giwa S, Lewis JK, Alvarez L, Langer R, Roth AE, Church GM, Markmann JF, Sachs DH, Chandraker A, Wertheim JA, Rothblatt M, Boyden ES, Eidbo E, Lee WPA, Pomahac B, Brandacher G, Weinstock DM, Elliott G, Nelson D, Acker JP, Uygun K, Schmalz B, Weegman BP, Tocchio A, Fahy GM, Storey KB, Rubinsky B, Bischof J, Elliott JAW, Woodruff TK, Morris GJ, Demirci U, Brockbank KGM, Woods EJ, Ben RN, Baust JG, Gao D, Fuller B, Rabin Y, Kravitz DC, Taylor MJ, Toner M.

Nat Biotechnol. 2017 Jun 7;35(6):530-542. doi: 10.1038/nbt.3889. Review.

43.

Microfluidic Isolation of Circulating Tumor Cell Clusters by Size and Asymmetry.

Au SH, Edd J, Stoddard AE, Wong KHK, Fachin F, Maheswaran S, Haber DA, Stott SL, Kapur R, Toner M.

Sci Rep. 2017 May 26;7(1):2433. doi: 10.1038/s41598-017-01150-3.

44.

Single-Cell Analysis of Circulating Tumor Cells as a Window into Tumor Heterogeneity.

Miyamoto DT, Ting DT, Toner M, Maheswaran S, Haber DA.

Cold Spring Harb Symp Quant Biol. 2016;81:269-274. doi: 10.1101/sqb.2016.81.031120. Epub 2017 Apr 7. Review.

45.

Controlled ice nucleation using freeze-dried Pseudomonas syringae encapsulated in alginate beads.

Weng L, Tessier SN, Swei A, Stott SL, Toner M.

Cryobiology. 2017 Apr;75:1-6. doi: 10.1016/j.cryobiol.2017.03.006. Epub 2017 Mar 14.

46.

Expression of β-globin by cancer cells promotes cell survival during blood-borne dissemination.

Zheng Y, Miyamoto DT, Wittner BS, Sullivan JP, Aceto N, Jordan NV, Yu M, Karabacak NM, Comaills V, Morris R, Desai R, Desai N, Emmons E, Milner JD, Lee RJ, Wu CL, Sequist LV, Haas W, Ting DT, Toner M, Ramaswamy S, Maheswaran S, Haber DA.

Nat Commun. 2017 Feb 9;8:14344. doi: 10.1038/ncomms14344.

47.

Enhanced Isolation and Release of Circulating Tumor Cells Using Nanoparticle Binding and Ligand Exchange in a Microfluidic Chip.

Park MH, Reátegui E, Li W, Tessier SN, Wong KH, Jensen AE, Thapar V, Ting D, Toner M, Stott SL, Hammond PT.

J Am Chem Soc. 2017 Feb 22;139(7):2741-2749. doi: 10.1021/jacs.6b12236. Epub 2017 Feb 9.

48.

An RNA-based signature enables high specificity detection of circulating tumor cells in hepatocellular carcinoma.

Kalinich M, Bhan I, Kwan TT, Miyamoto DT, Javaid S, LiCausi JA, Milner JD, Hong X, Goyal L, Sil S, Choz M, Ho U, Kapur R, Muzikansky A, Zhang H, Weitz DA, Sequist LV, Ryan DP, Chung RT, Zhu AX, Isselbacher KJ, Ting DT, Toner M, Maheswaran S, Haber DA.

Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):1123-1128. doi: 10.1073/pnas.1617032114. Epub 2017 Jan 17.

49.

Cytokeratin 7 in Oropharyngeal Squamous Cell Carcinoma: A Junctional Biomarker for Human Papillomavirus-Related Tumors.

Woods RSR, Keegan H, White C, Tewari P, Toner M, Kennedy S, O'Regan EM, Martin CM, Timon CVI, O'Leary JJ.

Cancer Epidemiol Biomarkers Prev. 2017 May;26(5):702-710. doi: 10.1158/1055-9965.EPI-16-0619. Epub 2017 Jan 12.

50.

HER2 expression identifies dynamic functional states within circulating breast cancer cells.

Jordan NV, Bardia A, Wittner BS, Benes C, Ligorio M, Zheng Y, Yu M, Sundaresan TK, Licausi JA, Desai R, O'Keefe RM, Ebright RY, Boukhali M, Sil S, Onozato ML, Iafrate AJ, Kapur R, Sgroi D, Ting DT, Toner M, Ramaswamy S, Haas W, Maheswaran S, Haber DA.

Nature. 2016 Sep 1;537(7618):102-106. doi: 10.1038/nature19328. Epub 2016 Aug 24.

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