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Use of adjunct cardiovascular therapy in patients hospitalised for acute exacerbations of COPD.

Roversi S, Tonelli R, Beghè B, Banchelli F, D'Amico R, Malerba M, Fabbri LM, Clini EM.

ERJ Open Res. 2018 Sep 12;4(3). pii: 00087-2018. doi: 10.1183/23120541.00087-2018. eCollection 2018 Jul.


An uncommon cause of hemoptysis: aortobronchial fistula.

Fontana M, Tonelli R, Gozzi F, Castaniere I, Marchioni A, Fantini R, Coppi F, Natali F, Rovatti E, Clini E.

Multidiscip Respir Med. 2018 Sep 10;13:25. doi: 10.1186/s40248-018-0146-3. eCollection 2018.


The encaged lung: rapidly progressive idiopathic pleurisy.

Castaniere I, Tonelli R, Fantini R, Marchioni A, Garofalo M, Clini EM, Cerri S.

Oxf Med Case Reports. 2018 Aug 9;2018(8):omy041. doi: 10.1093/omcr/omy041. eCollection 2018 Aug.


Ultrasound-assessed diaphragmatic impairment is a predictor of outcomes in patients with acute exacerbation of chronic obstructive pulmonary disease undergoing noninvasive ventilation.

Marchioni A, Castaniere I, Tonelli R, Fantini R, Fontana M, Tabbì L, Viani A, Giaroni F, Ruggieri V, Cerri S, Clini E.

Crit Care. 2018 Apr 27;22(1):109. doi: 10.1186/s13054-018-2033-x.


Acute exacerbation of idiopathic pulmonary fibrosis: lessons learned from acute respiratory distress syndrome?

Marchioni A, Tonelli R, Ball L, Fantini R, Castaniere I, Cerri S, Luppi F, Malerba M, Pelosi P, Clini E.

Crit Care. 2018 Mar 23;22(1):80. doi: 10.1186/s13054-018-2002-4. Review.


Incidence, Etiology, and Clinicopathologic Features of Endobronchial Benign Lesions: A 10-Year Consecutive Retrospective Study.

Marchioni A, Casalini E, Andreani A, Cappiello G, Castaniere I, Fantini R, Cecilia Mengoli M, Tonelli R, Clini EM, Rossi G.

J Bronchology Interv Pulmonol. 2018 Apr;25(2):118-124. doi: 10.1097/LBR.0000000000000460.


Looking for a chronic care model in COPD patients.

Clini E, Castaniere I, Tonelli R.

Eur Respir J. 2018 Jan 4;51(1). pii: 1702087. doi: 10.1183/13993003.02087-2017. Print 2018 Jan. No abstract available.


Effectiveness of pulmonary rehabilitation in patients with interstitial lung disease of different etiology: a multicenter prospective study.

Tonelli R, Cocconcelli E, Lanini B, Romagnoli I, Florini F, Castaniere I, Andrisani D, Cerri S, Luppi F, Fantini R, Marchioni A, Beghè B, Gigliotti F, Clini EM.

BMC Pulm Med. 2017 Oct 10;17(1):130. doi: 10.1186/s12890-017-0476-5.


An uncommon cause of pneumonia: The golden diagnosis.

Fabbri L, Tonelli R, Andreani A, Castaniere I, Fantini R, Marchioni A, Clini EM.

Respir Med Case Rep. 2017 Jun 21;22:51-52. doi: 10.1016/j.rmcr.2017.06.010. eCollection 2017.


The performance of the GAP model in patients with rheumatoid arthritis associated interstitial lung disease.

Morisset J, Vittinghoff E, Lee BY, Tonelli R, Hu X, Elicker BM, Ryu JH, Jones KD, Cerri S, Manfredi A, Sebastiani M, Gross AJ, Ley B, Wolters PJ, King TE Jr, Kim DS, Collard HR, Lee JS.

Respir Med. 2017 Jun;127:51-56. doi: 10.1016/j.rmed.2017.04.012. Epub 2017 Apr 22.


COPD exacerbation and diaphragmatic dysfunction: Conditions with mutual influence influencing outcomes? - Reply.

Marchioni A, Tonelli R, Antenora F, Fantini R, Clini EM.

Respirology. 2017 May;22(4):830-831. doi: 10.1111/resp.13018. Epub 2017 Mar 8. No abstract available.


Protein SUMOylation is Involved in Cell-cycle Progression and Cell Morphology in Giardia lamblia.

Di Genova BM, da Silva RC, da Cunha JPC, Gargantini PR, Mortara RA, Tonelli RR.

J Eukaryot Microbiol. 2017 Jul;64(4):491-503. doi: 10.1111/jeu.12386. Epub 2016 Dec 27.


Prevalence and outcomes of diaphragmatic dysfunction assessed by ultrasound technology during acute exacerbation of COPD: A pilot study.

Antenora F, Fantini R, Iattoni A, Castaniere I, Sdanganelli A, Livrieri F, Tonelli R, Zona S, Monelli M, Clini EM, Marchioni A.

Respirology. 2017 Feb;22(2):338-344. doi: 10.1111/resp.12916. Epub 2016 Oct 14.


When Acute Respiratory Distress Syndrome is not ARDS.

Tonelli R, Andreani A, Castaniere I, Fantini R, Mengoli C, Rossi G, Marchioni A.

Lung. 2016 Oct;194(5):865-6. doi: 10.1007/s00408-016-9917-9. Epub 2016 Jul 2. No abstract available.


Ultrasound assessment of diaphragmatic function in patients with amyotrophic lateral sclerosis.

Fantini R, Mandrioli J, Zona S, Antenora F, Iattoni A, Monelli M, Fini N, Tonelli R, Clini E, Marchioni A.

Respirology. 2016 Jul;21(5):932-8. doi: 10.1111/resp.12759. Epub 2016 Mar 19.


Infection Strategies of Intestinal Parasite Pathogens and Host Cell Responses.

Di Genova BM, Tonelli RR.

Front Microbiol. 2016 Mar 3;7:256. doi: 10.3389/fmicb.2016.00256. eCollection 2016. Review.


Novel drug targets for idiopathic pulmonary fibrosis.

Sgalla G, Cocconcelli E, Tonelli R, Richeldi L.

Expert Rev Respir Med. 2016 Feb 26:1-13. [Epub ahead of print]


Impaired function in the complex patient with COPD: a matter to be considered.

Tonelli R, Clini EM.

Rev Port Pneumol (2006). 2015 Sep-Oct;21(5):227-9. doi: 10.1016/j.rppnen.2015.08.001. No abstract available.


Breakthroughs in internal and respiratory medicine.

Roversi S, Tonelli R, Fabbri LM.

Lancet Respir Med. 2015 Aug;3(8):600-2. doi: 10.1016/S2213-2600(15)00251-9. Epub 2015 Jul 14. No abstract available.


The effect of bronchodilators on forced vital capacity measurement in patients with idiopathic pulmonary fibrosis.

Assayag D, Vittinghoff E, Ryerson CJ, Cocconcelli E, Tonelli R, Hu X, Elicker BM, Golden JA, Jones KD, King TE Jr, Koth LL, Lee JS, Ley B, Shum AK, Wolters PJ, Ryu JH, Collard HR.

Respir Med. 2015 Aug;109(8):1058-62. doi: 10.1016/j.rmed.2015.06.012. Epub 2015 Jun 24.


Diagnosis of Leishmania infection in a nonendemic area of South America.

Cargnelutti DE, Borremans CG, Tonelli RL, Carrizo LC, Salomón MC.

J Microbiol Immunol Infect. 2016 Oct;49(5):809-812. doi: 10.1016/j.jmii.2014.11.014. Epub 2014 Dec 11.


Prokineticin receptor identified by phage display is an entry receptor for Trypanosoma cruzi into mammalian cells.

Khusal KG, Tonelli RR, Mattos EC, Soares CO, Di Genova BM, Juliano MA, Urias U, Colli W, Alves MJ.

Parasitol Res. 2015 Jan;114(1):155-65. doi: 10.1007/s00436-014-4172-6. Epub 2014 Oct 17.


Sulforaphane induces apoptosis in rhabdomyosarcoma and restores TRAIL-sensitivity in the aggressive alveolar subtype leading to tumor elimination in mice.

Bergantin E, Quarta C, Nanni C, Fanti S, Pession A, Cantelli-Forti G, Tonelli R, Hrelia P.

Cancer Biol Ther. 2014 Sep;15(9):1219-25. doi: 10.4161/cbt.29684. Epub 2014 Jun 27.


MYCN is a novel oncogenic target in pediatric T-cell acute lymphoblastic leukemia.

Astolfi A, Vendemini F, Urbini M, Melchionda F, Masetti R, Franzoni M, Libri V, Serravalle S, Togni M, Paone G, Montemurro L, Bressanin D, Chiarini F, Martelli AM, Tonelli R, Pession A.

Oncotarget. 2014 Jan 15;5(1):120-30.


The Gp85 surface glycoproteins from Trypanosoma cruzi.

Mattos EC, Tonelli RR, Colli W, Alves MJ.

Subcell Biochem. 2014;74:151-80. doi: 10.1007/978-94-007-7305-9_7. Review.


Eukaryotic initiation factor 5A dephosphorylation is required for translational arrest in stationary phase cells.

Chung J, Rocha AA, Tonelli RR, Castilho BA, Schenkman S.

Biochem J. 2013 Apr 15;451(2):257-67. doi: 10.1042/BJ20121553.


A nature-inspired betalainic probe for live-cell imaging of Plasmodium-infected erythrocytes.

Gonçalves LC, Tonelli RR, Bagnaresi P, Mortara RA, Ferreira AG, Bastos EL.

PLoS One. 2013;8(1):e53874. doi: 10.1371/journal.pone.0053874. Epub 2013 Jan 16.


Selection of binding targets in parasites using phage-display and aptamer libraries in vivo and in vitro.

Tonelli RR, Colli W, Alves MJ.

Front Immunol. 2013 Jan 9;3:419. doi: 10.3389/fimmu.2012.00419. eCollection 2012.


Idiopathic pulmonary fibrosis: diagnostic pitfalls and therapeutic challenges.

Spagnolo P, Tonelli R, Cocconcelli E, Stefani A, Richeldi L.

Multidiscip Respir Med. 2012 Nov 12;7(1):42. doi: 10.1186/2049-6958-7-42.


Onset of chaotic phase synchronization in complex networks of coupled heterogeneous oscillators.

Ricci F, Tonelli R, Huang L, Lai YC.

Phys Rev E Stat Nonlin Soft Matter Phys. 2012 Aug;86(2 Pt 2):027201. Epub 2012 Aug 14.


Molecular imaging of neuroblastoma progression in TH-MYCN transgenic mice.

Quarta C, Cantelli E, Nanni C, Ambrosini V, D'ambrosio D, Di Leo K, Angelucci S, Zagni F, Lodi F, Marengo M, Weiss WA, Pession A, Tonelli R, Fanti S.

Mol Imaging Biol. 2013 Apr;15(2):194-202. doi: 10.1007/s11307-012-0576-9.


Generation and characterization of bioluminescent xenograft mouse models of MLL-related acute leukemias and in vivo evaluation of luciferase-targeting siRNA nanoparticles.

Fazzina R, Lombardini L, Mezzanotte L, Roda A, Hrelia P, Pession A, Tonelli R.

Int J Oncol. 2012 Aug;41(2):621-8. doi: 10.3892/ijo.2012.1504. Epub 2012 May 31.


Protein synthesis attenuation by phosphorylation of eIF2α is required for the differentiation of Trypanosoma cruzi into infective forms.

Tonelli RR, Augusto Lda S, Castilho BA, Schenkman S.

PLoS One. 2011;6(11):e27904. doi: 10.1371/journal.pone.0027904. Epub 2011 Nov 16.


Antitumor activity of sustained N-myc reduction in rhabdomyosarcomas and transcriptional block by antigene therapy.

Tonelli R, McIntyre A, Camerin C, Walters ZS, Di Leo K, Selfe J, Purgato S, Missiaglia E, Tortori A, Renshaw J, Astolfi A, Taylor KR, Serravalle S, Bishop R, Nanni C, Valentijn LJ, Faccini A, Leuschner I, Formica S, Reis-Filho JS, Ambrosini V, Thway K, Franzoni M, Summersgill B, Marchelli R, Hrelia P, Cantelli-Forti G, Fanti S, Corradini R, Pession A, Shipley J.

Clin Cancer Res. 2012 Feb 1;18(3):796-807. doi: 10.1158/1078-0432.CCR-11-1981. Epub 2011 Nov 7.


Feasibility and safety of adoptive immunotherapy with ex vivo-generated autologous, cytotoxic T lymphocytes in patients with solid tumor.

Montagna D, Turin I, Schiavo R, Montini E, Zaffaroni N, Villa R, Secondino S, Schiavetto I, Caliogna L, Locatelli F, Libri V, Pession A, Tonelli R, Maccario R, Siena S, Pedrazzoli P.

Cytotherapy. 2012 Jan;14(1):80-90. doi: 10.3109/14653249.2011.610303. Epub 2011 Sep 23.


Transient suppression of MLH1 allows effective single-nucleotide substitution by single-stranded DNA oligonucleotides.

Dekker M, de Vries S, Aarts M, Dekker R, Brouwers C, Wiebenga O, de Wind N, Cantelli E, Tonelli R, Te Riele H.

Mutat Res. 2011 Oct 1;715(1-2):52-60. doi: 10.1016/j.mrfmmm.2011.07.008. Epub 2011 Jul 27.


Effect of modified atmosphere packaging on Quality Index Method (QIM) scores of farmed gilthead seabream (Sparus aurata L.) at low and abused temperatures.

Campus M, Bonaglini E, Cappuccinelli R, Porcu MC, Tonelli R, Roggio T.

J Food Sci. 2011 Apr;76(3):S185-91. doi: 10.1111/j.1750-3841.2011.02051.x. Epub 2011 Mar 14.


Application of 2-D DIGE to formalin-fixed, paraffin-embedded tissues.

Tanca A, Pagnozzi D, Falchi G, Tonelli R, Rocca S, Roggio T, Uzzau S, Addis MF.

Proteomics. 2011 Mar;11(5):1005-11. doi: 10.1002/pmic.201000353. Epub 2011 Jan 31.


[Coccidioidomycosis in Argentina, 1892-2009].

Canteros CE, Toranzo A, Ibarra-Camou B, David V, Carrizo SG, Santillán-Iturres A, Serrano J, Fernández N, Capece P, Gorostiaga J, Chacón YA, Tonelli R, Boscaro G, Abiega C, Mendieta S, Fernández C, Fernández A, Vitale R, Santos P, Pizarro MR, López-Joffre MC, Lee W, Mazza M, Posse G, Tiraboschi IN, Negroni R, Davel G.

Rev Argent Microbiol. 2010 Oct-Dec;42(4):261-8. doi: 10.1590/S0325-75412010000400004. Spanish.


NMR analysis of seven selections of vermentino grape berry: metabolites composition and development.

Mulas G, Galaffu MG, Pretti L, Nieddu G, Mercenaro L, Tonelli R, Anedda R.

J Agric Food Chem. 2011 Feb 9;59(3):793-802. doi: 10.1021/jf103285f. Epub 2011 Jan 12.


Proteomic analysis of formalin-fixed, paraffin-embedded lung neuroendocrine tumor samples from hospital archives.

Tanca A, Addis MF, Pagnozzi D, Cossu-Rocca P, Tonelli R, Falchi G, Eccher A, Roggio T, Fanciulli G, Uzzau S.

J Proteomics. 2011 Mar 1;74(3):359-70. doi: 10.1016/j.jprot.2010.12.001. Epub 2010 Dec 13.


Role of the gp85/trans-sialidases in Trypanosoma cruzi tissue tropism: preferential binding of a conserved peptide motif to the vasculature in vivo.

Tonelli RR, Giordano RJ, Barbu EM, Torrecilhas AC, Kobayashi GS, Langley RR, Arap W, Pasqualini R, Colli W, Alves MJ.

PLoS Negl Trop Dis. 2010 Nov 2;4(11):e864. doi: 10.1371/journal.pntd.0000864.


In vivo infection by Trypanosoma cruzi: the conserved FLY domain of the gp85/trans-sialidase family potentiates host infection.

Tonelli RR, Torrecilhas AC, Jacysyn JF, Juliano MA, Colli W, Alves MJ.

Parasitology. 2011 Apr;138(4):481-92. doi: 10.1017/S0031182010001411. Epub 2010 Nov 2.


Target of rapamycin (TOR)-like 1 kinase is involved in the control of polyphosphate levels and acidocalcisome maintenance in Trypanosoma brucei.

de Jesus TC, Tonelli RR, Nardelli SC, da Silva Augusto L, Motta MC, Girard-Dias W, Miranda K, Ulrich P, Jimenez V, Barquilla A, Navarro M, Docampo R, Schenkman S.

J Biol Chem. 2010 Jul 30;285(31):24131-40. doi: 10.1074/jbc.M110.120212. Epub 2010 May 21.


Chagas' disease: an update on immune mechanisms and therapeutic strategies.

Boscardin SB, Torrecilhas AC, Manarin R, Revelli S, Rey EG, Tonelli RR, Silber AM.

J Cell Mol Med. 2010 Jun;14(6B):1373-84. doi: 10.1111/j.1582-4934.2010.01007.x. Epub 2010 Jan 11. Review.


Similar favorable outcome of pegfilgrastim overdose in patients with different age and underlying disease.

Dufour C, Cappelli B, Calvillo M, Fioredda F, Tonelli R, Crocchiolo R.

Haematologica. 2010 Apr;95(4):684-5. doi: 10.3324/haematol.2009.018333. Epub 2010 Jan 6. No abstract available.


In vivo bioluminescence imaging of murine xenograft cancer models with a red-shifted thermostable luciferase.

Mezzanotte L, Fazzina R, Michelini E, Tonelli R, Pession A, Branchini B, Roda A.

Mol Imaging Biol. 2010 Aug;12(4):406-14. doi: 10.1007/s11307-009-0291-3. Epub 2009 Nov 25.


Pegfilgrastim in children with severe congenital neutropenia.

Fioredda F, Calvillo M, Lanciotti M, Lanza T, Giunti L, Castagnola E, Lorenzi I, Tonelli R, Ghezzi P, Dufour C.

Pediatr Blood Cancer. 2010 Mar;54(3):465-7. doi: 10.1002/pbc.22350.


Glucose uptake in the mammalian stages of Trypanosoma cruzi.

Silber AM, Tonelli RR, Lopes CG, Cunha-e-Silva N, Torrecilhas AC, Schumacher RI, Colli W, Alves MJ.

Mol Biochem Parasitol. 2009 Nov;168(1):102-8. doi: 10.1016/j.molbiopara.2009.07.006. Epub 2009 Jul 23.


Down-regulation of HOXA4, HOXA7, HOXA10, HOXA11 and MEIS1 during monocyte-macrophage differentiation in THP-1 cells.

Martino V, Bianchera A, Reia L, Bussolati O, Fazzina R, Marino F, Montemurro L, Tonelli R, Pession A, Gazzola GC, Sala R.

Mol Med Rep. 2009 Mar-Apr;2(2):241-4. doi: 10.3892/mmr_00000090.


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