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Items: 11

1.

KUNO-Kids birth cohort study: rationale, design, and cohort description.

Brandstetter S, Toncheva AA, Niggel J, Wolff C, Gran S, Seelbach-Göbel B, Apfelbacher C, Melter M, Kabesch M; KUNO-Kids study group.

Mol Cell Pediatr. 2019 Jan 9;6(1):1. doi: 10.1186/s40348-018-0088-z.

2.

Protective effects of breastfeeding on respiratory symptoms in infants with 17q21 asthma risk variants.

Gorlanova O, Illi S, Toncheva AA, Usemann J, Latzin P, Kabesch M, Dalphin JC, Lauener R, Pekkanen JR, Von Mutius E, Riedler J, Kuehni CE, Röösli M, Frey U; BILD and PASTURE study groups.

Allergy. 2018 Dec;73(12):2388-2392. doi: 10.1111/all.13568. Epub 2018 Aug 9. No abstract available.

PMID:
30030842
3.

Asthmatic farm children show increased CD3+CD8low T-cells compared to non-asthmatic farm children.

Twardziok M, Schröder PC, Krusche J, Casaca VI, Illi S, Böck A, Loss GJ, Kabesch M, Toncheva AA, Roduit C, Depner M, Genuneit J, Renz H, Roponen M, Weber J, Braun-Fahrländer C, Riedler J, Lauener R, Vuitton DA, Dalphin JC, Pekkanen J, von Mutius E, Schaub B; PASTURE Study Group:, Hyvärinen A, Karvonen AM, Kirjavainen PV, Remes S, Kaulek V, Dalphin ML, Ege M, Pfefferle PI, Doekes G.

Clin Immunol. 2017 Oct;183:285-292. doi: 10.1016/j.clim.2017.09.009. Epub 2017 Sep 13. No abstract available.

PMID:
28917722
4.

6q12 and 11p14 variants are associated with postnatal exhaled nitric oxide levels and respiratory symptoms.

Fuchs O, Gorlanova O, Latzin P, Schmidt A, Schieck M, Toncheva AA, Michel S, Gaertner VD, Kabesch M, Frey U.

J Allergy Clin Immunol. 2017 Oct;140(4):1015-1023. doi: 10.1016/j.jaci.2016.11.048. Epub 2017 Jan 19.

PMID:
28109725
5.

Doublesex and mab-3 related transcription factor 1 (DMRT1) is a sex-specific genetic determinant of childhood-onset asthma and is expressed in testis and macrophages.

Schieck M, Schouten JP, Michel S, Suttner K, Toncheva AA, Gaertner VD, Illig T, Lipinski S, Franke A, Klintschar M, Kalayci O, Sahiner UM, Birben E, Melén E, Pershagen G, Freidin MB, Ogorodova LM, Granell R, Henderson J, Brunekreef B, Smit HA, Vogelberg C, von Berg A, Bufe A, Heinzmann A, Laub O, Rietschel E, Simma B, Genuneit J, Jonigk D, Postma DS, Koppelman GH, Vonk JM, Timens W, Boezen HM, Kabesch M.

J Allergy Clin Immunol. 2016 Aug;138(2):421-31. doi: 10.1016/j.jaci.2015.12.1305. Epub 2016 Feb 20.

PMID:
26906082
6.

The cAMP response element modulator (CREM) regulates TH2 mediated inflammation.

Verjans E, Ohl K, Reiss LK, van Wijk F, Toncheva AA, Wiener A, Yu Y, Rieg AD, Gaertner VD, Roth J, Knol E, Kabesch M, Wagner N, Uhlig S, Martin C, Tenbrock K.

Oncotarget. 2015 Nov 17;6(36):38538-51. doi: 10.18632/oncotarget.6041.

7.

Childhood asthma is associated with mutations and gene expression differences of ORMDL genes that can interact.

Toncheva AA, Potaczek DP, Schedel M, Gersting SW, Michel S, Krajnov N, Gaertner VD, Klingbeil JM, Illig T, Franke A, Winkler C, Hohlfeld JM, Vogelberg C, von Berg A, Bufe A, Heinzmann A, Laub O, Rietschel E, Simma B, Genuneit J, Muntau AC, Kabesch M.

Allergy. 2015 Oct;70(10):1288-99. doi: 10.1111/all.12652. Epub 2015 Jul 20.

PMID:
26011647
8.

Polymorphisms related to ORMDL3 are associated with asthma susceptibility, alterations in transcriptional regulation of ORMDL3, and changes in TH2 cytokine levels.

Schedel M, Michel S, Gaertner VD, Toncheva AA, Depner M, Binia A, Schieck M, Rieger MT, Klopp N, von Berg A, Bufe A, Laub O, Rietschel E, Heinzmann A, Simma B, Vogelberg C, Genuneit J, Illig T, Kabesch M.

J Allergy Clin Immunol. 2015 Oct;136(4):893-903.e14. doi: 10.1016/j.jaci.2015.03.014. Epub 2015 Apr 28.

PMID:
25930191
9.

A polymorphism in the TH 2 locus control region is associated with changes in DNA methylation and gene expression.

Schieck M, Sharma V, Michel S, Toncheva AA, Worth L, Potaczek DP, Genuneit J, Kretschmer A, Depner M, Dalphin JC, Riedler J, Frei R, Pekkanen J, Tost J, Kabesch M.

Allergy. 2014 Sep;69(9):1171-80. doi: 10.1111/all.12450. Epub 2014 Jul 14.

PMID:
24866380
10.

Genetic variants in Protocadherin-1, bronchial hyper-responsiveness, and asthma subphenotypes in German children.

Toncheva AA, Suttner K, Michel S, Klopp N, Illig T, Balschun T, Vogelberg C, von Berg A, Bufe A, Heinzmann A, Laub O, Rietschel E, Simma B, Frischer T, Genuneit J, von Mutius E, Kabesch M.

Pediatr Allergy Immunol. 2012 Nov;23(7):636-41. doi: 10.1111/j.1399-3038.2012.01334.x. Epub 2012 Oct 11.

PMID:
23050600
11.

Gingival disease and secretory immunoglobulin a in non-stimulated saliva in children.

Rashkova MP, Toncheva AA.

Folia Med (Plovdiv). 2010 Oct-Dec;52(4):48-55.

PMID:
21462892

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