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Items: 1 to 50 of 88

1.

GS-5806 Inhibits a Broad Range of Respiratory Syncytial Virus Clinical Isolates by Blocking the Virus-Cell Fusion Process.

Perron M, Stray K, Kinkade A, Theodore D, Lee G, Eisenberg E, Sangi M, Gilbert BE, Jordan R, Piedra PA, Toms GL, Mackman R, Cihlar T.

Antimicrob Agents Chemother. 2015 Dec 14;60(3):1264-73. doi: 10.1128/AAC.01497-15.

2.

PCSK9, apolipoprotein E and lipoviral particles in chronic hepatitis C genotype 3: evidence for genotype-specific regulation of lipoprotein metabolism.

Bridge SH, Sheridan DA, Felmlee DJ, Crossey MM, Fenwick FI, Lanyon CV, Dubuc G, Seidah NG, Davignon J, Thomas HC, Taylor-Robinson SD, Toms GL, Neely RD, Bassendine MF.

J Hepatol. 2015 Apr;62(4):763-70. doi: 10.1016/j.jhep.2014.11.016. Epub 2014 Nov 21.

PMID:
25463543
3.

Imaging analysis of human metapneumovirus-infected cells provides evidence for the involvement of F-actin and the raft-lipid microdomains in virus morphogenesis.

Jumat MR, Nguyen Huong T, Wong P, Loo LH, Tan BH, Fenwick F, Toms GL, Sugrue RJ.

Virol J. 2014 Nov 19;11:198. doi: 10.1186/s12985-014-0198-8.

4.
5.

Generation and epitope mapping of a sub-group cross-reactive anti-respiratory syncytial virus G glycoprotein monoclonal antibody which is protective in vivo.

Robinson MJ, Tan CS, Fenwick F, Chambers CJ, Routledge EG, Toms GL.

J Med Virol. 2014 Jul;86(7):1267-77. doi: 10.1002/jmv.23881. Epub 2014 Jan 10.

PMID:
24415460
6.

Immunogenicity in mice of human metapneumovirus with a truncated SH glycoprotein.

Tedcastle AB, Fenwick F, Robinson MJ, Toms GL.

J Med Virol. 2014 Apr;86(4):547-57. doi: 10.1002/jmv.23731. Epub 2013 Sep 5.

PMID:
24009128
7.

The characterization of monoclonal antibodies to human metapneumovirus and the detection of multiple forms of the virus nucleoprotein and phosphoprotein.

Tedcastle AB, Fenwick F, Ingram RE, King BJ, Robinson MJ, Toms GL.

J Med Virol. 2012 Jul;84(7):1061-70. doi: 10.1002/jmv.23298.

PMID:
22585723
8.

Apolipoprotein-E and hepatitis C lipoviral particles in genotype 1 infection: evidence for an association with interferon sensitivity.

Sheridan DA, Bridge SH, Felmlee DJ, Crossey MM, Thomas HC, Taylor-Robinson SD, Toms GL, Neely RD, Bassendine MF.

J Hepatol. 2012 Jul;57(1):32-8. doi: 10.1016/j.jhep.2012.02.017. Epub 2012 Mar 10.

PMID:
22414761
9.

HCV and the hepatic lipid pathway as a potential treatment target.

Bassendine MF, Sheridan DA, Felmlee DJ, Bridge SH, Toms GL, Neely RD.

J Hepatol. 2011 Dec;55(6):1428-40. doi: 10.1016/j.jhep.2011.06.004. Epub 2011 Jun 28. Review.

10.

Molecular epidemiology and evolution of human respiratory syncytial virus and human metapneumovirus.

Gaunt ER, Jansen RR, Poovorawan Y, Templeton KE, Toms GL, Simmonds P.

PLoS One. 2011 Mar 1;6(3):e17427. doi: 10.1371/journal.pone.0017427.

11.

Insulin resistance and low-density apolipoprotein B-associated lipoviral particles in hepatitis C virus genotype 1 infection.

Bridge SH, Sheridan DA, Felmlee DJ, Nielsen SU, Thomas HC, Taylor-Robinson SD, Neely RD, Toms GL, Bassendine MF.

Gut. 2011 May;60(5):680-7. doi: 10.1136/gut.2010.222133. Epub 2010 Oct 12.

PMID:
20940286
12.

Intravascular transfer contributes to postprandial increase in numbers of very-low-density hepatitis C virus particles.

Felmlee DJ, Sheridan DA, Bridge SH, Nielsen SU, Milne RW, Packard CJ, Caslake MJ, McLauchlan J, Toms GL, Neely RD, Bassendine MF.

Gastroenterology. 2010 Nov;139(5):1774-83, 1783.e1-6. doi: 10.1053/j.gastro.2010.07.047. Epub 2010 Aug 2.

PMID:
20682323
13.

Apolipoprotein B-associated cholesterol is a determinant of treatment outcome in patients with chronic hepatitis C virus infection receiving anti-viral agents interferon-alpha and ribavirin.

Sheridan DA, Price DA, Schmid ML, Toms GL, Donaldson P, Neely D, Bassendine MF.

Aliment Pharmacol Ther. 2009 Jun 15;29(12):1282-90. doi: 10.1111/j.1365-2036.2009.04012.x. Epub 2009 Apr 8.

14.

Characterization of hepatitis C RNA-containing particles from human liver by density and size.

Nielsen SU, Bassendine MF, Martin C, Lowther D, Purcell PJ, King BJ, Neely D, Toms GL.

J Gen Virol. 2008 Oct;89(Pt 10):2507-17. doi: 10.1099/vir.0.2008/000083-0.

15.

Protein kinase A-dependent step(s) in hepatitis C virus entry and infectivity.

Farquhar MJ, Harris HJ, Diskar M, Jones S, Mee CJ, Nielsen SU, Brimacombe CL, Molina S, Toms GL, Maurel P, Howl J, Herberg FW, van Ijzendoorn SC, Balfe P, McKeating JA.

J Virol. 2008 Sep;82(17):8797-811. doi: 10.1128/JVI.00592-08. Epub 2008 Jun 25.

16.

Binding of liver derived, low density hepatitis C virus to human hepatoma cells.

Martin C, Nielsen SU, Ibrahim S, Bassendine MF, Toms GL.

J Med Virol. 2008 May;80(5):816-23. doi: 10.1002/jmv.21150.

17.

Molecular epidemiology of human metapneumovirus in Ireland.

Carr MJ, Waters A, Fenwick F, Toms GL, Hall WW, O'Kelly E.

J Med Virol. 2008 Mar;80(3):510-6. doi: 10.1002/jmv.21081.

PMID:
18205227
18.

Purification of human respiratory syncytial virus by ultracentrifugation in iodixanol density gradient.

Gias E, Nielsen SU, Morgan LA, Toms GL.

J Virol Methods. 2008 Feb;147(2):328-32. Epub 2007 Oct 29.

19.

Diagnosis of human metapneumovirus by immunofluorescence staining with monoclonal antibodies in the North-East of England.

Fenwick F, Young B, McGuckin R, Robinson MJ, Taha Y, Taylor CE, Toms GL.

J Clin Virol. 2007 Nov;40(3):193-6. Epub 2007 Sep 14.

PMID:
17869169
23.

Association between hepatitis C virus and very-low-density lipoprotein (VLDL)/LDL analyzed in iodixanol density gradients.

Nielsen SU, Bassendine MF, Burt AD, Martin C, Pumeechockchai W, Toms GL.

J Virol. 2006 Mar;80(5):2418-28.

24.

Immunohistochemical assessment of hepatitis C virus antigen in cholestatic hepatitis after liver transplantation.

Fenwick F, Bassendine MF, Agarwal K, Bevitt D, Pumeechockchai W, Burt AD, Toms GL.

J Clin Pathol. 2006 Feb;59(2):174-8.

25.

Apolipoprotein epsilon3 allele is associated with persistent hepatitis C virus infection.

Price DA, Bassendine MF, Norris SM, Golding C, Toms GL, Schmid ML, Morris CM, Burt AD, Donaldson PT.

Gut. 2006 May;55(5):715-8. Epub 2005 Nov 18.

27.

Detection of human respiratory syncytial virus genotype specific antibody responses in infants.

McGill A, Greensill J, Marsh R, Craft AW, Toms GL.

J Med Virol. 2004 Nov;74(3):492-8.

PMID:
15368511
28.

Characterization of the genome and structural proteins of hepatitis C virus resolved from infected human liver.

Nielsen SU, Bassendine MF, Burt AD, Bevitt DJ, Toms GL.

J Gen Virol. 2004 Jun;85(Pt 6):1497-507.

29.

Measurement of antibody against contemporary virus lineages of human respiratory syncytial virus sub-group A in infants and their mothers.

McGill A, Greensill J, Craft AW, Fenwick F, Toms GL.

J Clin Virol. 2004 May;30(1):73-80.

PMID:
15072758
30.

Hepatitis C virus particles of different density in the blood of chronically infected immunocompetent and immunodeficient patients: Implications for virus clearance by antibody.

Pumeechockchai W, Bevitt D, Agarwal K, Petropoulou T, Langer BC, Belohradsky B, Bassendine MF, Toms GL.

J Med Virol. 2002 Nov;68(3):335-42.

PMID:
12226819
32.

Comparison of cytotoxic T-lymphocyte responses to hepatitis C virus core protein in uninfected and infected individuals.

Jackson M, Smith B, Bevitt DJ, Steward M, Toms GL, Bassendine MF, Diamond AG.

J Med Virol. 1999 Jul;58(3):239-46.

PMID:
10447419
33.

Outcome of post-transfusion hepatitis C: disease severity in blood-component recipients and their implicated donors.

Smith BC, Chapman CE, Burt AD, Toms GL, Bassendine MF.

QJM. 1997 Sep;90(9):587-92.

PMID:
9349451
34.

New monoclonal antibodies to oestrogen and progesterone receptors effective for paraffin section immunohistochemistry.

Bevitt DJ, Milton ID, Piggot N, Henry L, Carter MJ, Toms GL, Lennard TW, Westley B, Angus B, Horne CH.

J Pathol. 1997 Oct;183(2):228-32.

PMID:
9390038
35.
36.
37.

Undetectable IgE responses after respiratory syncytial virus infection.

Toms GL, Quinn R, Robinson JW.

Arch Dis Child. 1996 Feb;74(2):126-30.

38.
39.

Prokaryotic expression and analysis of the antibody response to a Newcastle isolate of the core gene of hepatitis C.

Milton ID, Watson JP, Guo K, Carter MJ, Bassendine MF, Toms GL.

J Med Virol. 1995 Mar;45(3):253-8.

PMID:
7539832
40.

Respiratory syncytial virus--how soon will we have a vaccine?

Toms GL.

Arch Dis Child. 1995 Jan;72(1):1-3. No abstract available.

41.

Biological activity, binding site and affinity of monoclonal antibodies to the fusion protein of respiratory syncytial virus.

West WH, Lounsbach GR, Bourgeois C, Robinson JW, Carter MJ, Crompton S, Duhindan N, Yazici ZA, Toms GL.

J Gen Virol. 1994 Oct;75 ( Pt 10):2813-9.

PMID:
7931172
42.

Binding of neutralizing monoclonal antibodies to regions of the fusion protein of respiratory syncytial virus expressed in Escherichia coli.

Lounsbach GR, Bourgeois C, West WH, Robinson JW, Carter MJ, Toms GL.

J Gen Virol. 1993 Dec;74 ( Pt 12):2559-65.

PMID:
7506297
43.

T cell function in children with acute lymphoblastic leukaemia.

Nash KA, Mohammed G, Nandapalan N, Kernahan J, Scott R, Craft AW, Toms GL.

Br J Haematol. 1993 Mar;83(3):419-27.

PMID:
8485047
44.

Recognition of respiratory syncytial (RS) virus proteins by human and BALB/C CD4+ lymphocytes.

Anderson JJ, Harrop JA, Peers H, Turnbull T, Toms GL, Scott R.

J Med Virol. 1991 Nov;35(3):165-73.

PMID:
1839552
45.

Vaccination against respiratory syncytial virus: problems and progress.

Toms GL.

FEMS Microbiol Immunol. 1991 Oct;3(5):243-56. Review. No abstract available.

PMID:
1797047
46.

Analysis of the local and systemic immune responses induced in BALB/c mice by experimental respiratory syncytial virus infection.

Anderson JJ, Norden J, Saunders D, Toms GL, Scott R.

J Gen Virol. 1990 Jul;71 ( Pt 7):1561-70.

PMID:
2197371
47.

Local antibody production and respiratory syncytial virus infection in children with leukaemia.

Taylor CE, Craft AW, Kernahan J, Millman R, Reid MM, Scott R, Toms GL.

J Med Virol. 1990 Apr;30(4):277-81.

PMID:
2370522
48.

Respiratory syncytial virus: virology, diagnosis, and vaccination.

Toms GL.

Lung. 1990;168 Suppl:388-95. Review.

PMID:
1696677
49.

IgG and IgM antibodies to viral glycoproteins in respiratory syncytial virus infections of graded severity.

Toms GL, Webb MS, Milner PD, Milner AD, Routledge EG, Scott R, Stokes GM, Swarbrick A, Taylor CE.

Arch Dis Child. 1989 Dec;64(12):1661-5.

50.

Interferon alfa, infectious virus, and virus antigen secretion in respiratory syncytial virus infections of graded severity.

Taylor CE, Webb MS, Milner AD, Milner PD, Morgan LA, Scott R, Stokes GM, Swarbrick AS, Toms GL.

Arch Dis Child. 1989 Dec;64(12):1656-60.

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