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Items: 1 to 50 of 418

1.

Developing Effective Alzheimer's Disease Therapies: Clinical Experience and Future Directions.

Elmaleh DR, Farlow MR, Conti PS, Tompkins RG, Kundakovic L, Tanzi RE.

J Alzheimers Dis. 2019 Aug 27. doi: 10.3233/JAD-190507. [Epub ahead of print]

PMID:
31476157
2.

Coenzyme Q10 protects against burn-induced mitochondrial dysfunction and impaired insulin signaling in mouse skeletal muscle.

Nakazawa H, Ikeda K, Shinozaki S, Yasuhara S, Yu YM, Martyn JAJ, Tompkins RG, Yorozu T, Inoue S, Kaneki M.

FEBS Open Bio. 2019 Jan 19;9(2):348-363. doi: 10.1002/2211-5463.12580. eCollection 2019 Feb.

3.

Prospective Validation of a Transcriptomic Metric in Severe Trauma.

Raymond SL, Hawkins RB, Wang Z, Mira JC, Stortz JA, Han F, Lanz JD, Hennessy LV, Brumback BA, Baker HV, Efron PA, Brakenridge SC, Xiao W, Tompkins RG, Cuschieri J, Moore FA, Maier RV, Moldawer LL.

Ann Surg. 2019 Jan 24. doi: 10.1097/SLA.0000000000003204. [Epub ahead of print]

PMID:
30688688
4.

The Effect of Facial Burns on Long-Term Outcomes in Young Adults: A 5-Year Study.

Ryan CM, Lee A, Stoddard FJ Jr, Li NC, Schneider JC, Shapiro GD, Griggs CL, Wang C, Palmieri T, Meyer WJ 3rd, Pidcock FS, Reilly D, Sheridan RL, Kazis LE, Tompkins RG; Multi-Center Benchmarking Study Group.

J Burn Care Res. 2018 Jun 13;39(4):497-506. doi: 10.1093/jbcr/irx006.

PMID:
29901795
5.

Platelet transfusion increases risk for acute respiratory distress syndrome in non-massively transfused blunt trauma patients.

Kasotakis G, Starr N, Nelson E, Sarkar B, Burke PA, Remick DG, Tompkins RG; Inflammation and Host Response to Injury Investigators.

Eur J Trauma Emerg Surg. 2019 Aug;45(4):671-679. doi: 10.1007/s00068-018-0953-4. Epub 2018 Apr 7.

PMID:
29627883
6.

Development of clinical process measures for pediatric burn care: Understanding variation in practice patterns.

Kazis LE, Sheridan RL, Shapiro GD, Lee AF, Liang MH, Ryan CM, Schneider JC, Lydon M, Soley-Bori M, Sonis LA, Dore EC, Palmieri T, Herndon D, Meyer W, Warner P, Kagan R, Stoddard FJ, Murphy M, Tompkins RG.

J Trauma Acute Care Surg. 2018 Apr;84(4):620-627. doi: 10.1097/TA.0000000000001737.

PMID:
29140950
7.

Burn-induced muscle metabolic derangements and mitochondrial dysfunction are associated with activation of HIF-1α and mTORC1: Role of protein farnesylation.

Nakazawa H, Ikeda K, Shinozaki S, Kobayashi M, Ikegami Y, Fu M, Nakamura T, Yasuhara S, Yu YM, Martyn JAJ, Tompkins RG, Shimokado K, Yorozu T, Ito H, Inoue S, Kaneki M.

Sci Rep. 2017 Jul 26;7(1):6618. doi: 10.1038/s41598-017-07011-3.

8.

Adult-onset, chronic, cyclic thrombocytopenia in a Rhesus macaque (Macaca mulatta) after dengue virus vaccination and viral challenge.

Frydman GH, Metcalf Pate KA, Marini RP, de Laforcade AM, Bosch I, Bakthavatchalu V, Muthupalani S, Swennes AG, Lyons CE, Tompkins RG, Fox JG.

Vet Clin Pathol. 2017 Jun;46(2):238-247. doi: 10.1111/vcp.12497. Epub 2017 May 18.

9.

Local and Systemic Changes Associated with Long-term, Percutaneous, Static Implantation of Titanium Alloys in Rhesus Macaques (Macaca mulatta).

Frydman GH, Marini RP, Bakthavatchalu V, Biddle KE, Muthupalani S, Vanderburg CR, Lai B, Bendapudi PK, Tompkins RG, Fox JG.

Comp Med. 2017 Mar 1;67(2):165-175.

10.

An ALPHA7 Nicotinic Acetylcholine Receptor Agonist (GTS-21) Promotes C2C12 Myonuclear Accretion in Association with Release of Interleukin-6 (IL-6) and Improves Survival in Burned Mice.

Khan MAS, Khan MF, Kashiwagi S, Kem WR, Yasuhara S, Kaneki M, Tompkins RG, Martyn JAJ.

Shock. 2017 Aug;48(2):227-235. doi: 10.1097/SHK.0000000000000849.

11.

iNOS as a Driver of Inflammation and Apoptosis in Mouse Skeletal Muscle after Burn Injury: Possible Involvement of Sirt1 S-Nitrosylation-Mediated Acetylation of p65 NF-κB and p53.

Nakazawa H, Chang K, Shinozaki S, Yasukawa T, Ishimaru K, Yasuhara S, Yu YM, Martyn JA, Tompkins RG, Shimokado K, Kaneki M.

PLoS One. 2017 Jan 18;12(1):e0170391. doi: 10.1371/journal.pone.0170391. eCollection 2017.

12.

Hold the Pendulum: Rates of Acute Kidney Injury are Increased in Patients Who Receive Resuscitation Volumes Less than Predicted by the Parkland Equation.

Mason SA, Nathens AB, Finnerty CC, Gamelli RL, Gibran NS, Arnoldo BD, Tompkins RG, Herndon DN, Jeschke MG; Inflammation and the Host Response to Injury Collaborative Research Program.

Ann Surg. 2016 Dec;264(6):1142-1147.

13.

KERIS: kaleidoscope of gene responses to inflammation between species.

Li P, Tompkins RG, Xiao W; the Inflammation and Host Response to Injury Large-Scale Collaborative Research Program.

Nucleic Acids Res. 2017 Jan 4;45(D1):D908-D914. doi: 10.1093/nar/gkw974. Epub 2016 Oct 26.

14.

TNF-α/IL-10 Ratio Correlates with Burn Severity and May Serve as a Risk Predictor of Increased Susceptibility to Infections.

Tsurumi A, Que YA, Ryan CM, Tompkins RG, Rahme LG.

Front Public Health. 2016 Oct 5;4:216. eCollection 2016.

15.

The metabolic stress response to burn trauma: current understanding and therapies.

Porter C, Tompkins RG, Finnerty CC, Sidossis LS, Suman OE, Herndon DN.

Lancet. 2016 Oct 1;388(10052):1417-1426. doi: 10.1016/S0140-6736(16)31469-6. Review.

16.

Technical Advance: Changes in neutrophil migration patterns upon contact with platelets in a microfluidic assay.

Frydman GH, Le A, Ellett F, Jorgensen J, Fox JG, Tompkins RG, Irimia D.

J Leukoc Biol. 2017 Mar;101(3):797-806. doi: 10.1189/jlb.1TA1115-517RR. Epub 2016 Sep 14.

17.

Prevention of Burn-Induced Inflammatory Responses and Muscle Wasting by GTS-21, a Specific Agonist for α7 Nicotinic Acetylcholine Receptors.

Kashiwagi S, Khan MA, Yasuhara S, Goto T, Kem WR, Tompkins RG, Kaneki M, Martyn JA.

Shock. 2017 Jan;47(1):61-69.

18.

Molecular Imaging of Smoke-Induced Changes in Nuclear Factor-Kappa B Expression in Murine Tissues Including the Lung.

Syrkina O, Hales CH, Bonab AA, Hamrahi V, Paul K, Jung WJ, Tompkins RG, Fischman AJ, Carter EA.

J Burn Care Res. 2016 Nov/Dec;37(6):335-342.

PMID:
27437954
19.

Reversal of Growth Arrest With the Combined Administration of Oxandrolone and Propranolol in Severely Burned Children.

Herndon DN, Voigt CD, Capek KD, Wurzer P, Guillory A, Kline A, Andersen CR, Klein GL, Tompkins RG, Suman OE, Finnerty CC, Meyer WJ, Sousse LE.

Ann Surg. 2016 Sep;264(3):421-8. doi: 10.1097/SLA.0000000000001844.

20.

Coagulation Biomarkers in Healthy Chinese-Origin Rhesus Macaques (Macaca mulatta).

Frydman GH, Bendapudi PK, Marini RP, Vanderburg CR, Tompkins RG, Fox JG.

J Am Assoc Lab Anim Sci. 2016;55(3):252-9.

21.

Role of Elevated Fibrinogen in Burn-Induced Mitochondrial Dysfunction: Protective Effects of Glycyrrhizin.

Ueki R, Liu L, Kashiwagi S, Kaneki M, Khan MA, Hirose M, Tompkins RG, Martyn JA, Yasuhara S.

Shock. 2016 Oct;46(4):382-9. doi: 10.1097/SHK.0000000000000602.

22.

Quantifying Risk Factors for Long-Term Sleep Problems After Burn Injury in Young Adults.

Lee AF, Ryan CM, Schneider JC, Kazis LE, Li NC, Rose M, Liang MH, Wang C, Palmieri T, Meyer WJ 3rd, Pidcock FS, Reilly D, Sheridan RL, Tompkins RG; and the Multi-Center Benchmarking Study Group.

J Burn Care Res. 2017 Mar/Apr;38(2):e510-e520. doi: 10.1097/BCR.0000000000000315.

PMID:
27003738
23.

Recovery Curves for Pediatric Burn Survivors: Advances in Patient-Oriented Outcomes.

Kazis LE, Lee AF, Rose M, Liang MH, Li NC, Ren XS, Sheridan R, Gilroy-Lewis J, Stoddard F, Hinson M, Warden G, Stubbs K, Blakeney P, Meyer W 3rd, McCauley R, Herndon D, Palmieri T, Mooney K, Wood D, Pidcock F, Reilly D, Cullen M, Calvert C, Ryan CM, Schneider JC, Soley-Bori M, Tompkins RG.

JAMA Pediatr. 2016 Jun 1;170(6):534-42. doi: 10.1001/jamapediatrics.2015.4722.

PMID:
26953515
24.

The burn outcome questionnaires: Patient and family reported outcome metrics for children of all ages.

Ryan CM, Cartwright S, Schneider JC, Tompkins RG, Kazis LE.

Burns. 2016 Aug;42(5):1144-1145. doi: 10.1016/j.burns.2015.10.033. Epub 2016 Jan 21. No abstract available.

PMID:
26803370
25.

In vivo high-resolution magic angle spinning magnetic and electron paramagnetic resonance spectroscopic analysis of mitochondria-targeted peptide in Drosophila melanogaster with trauma-induced thoracic injury.

Constantinou C, Apidianakis Y, Psychogios N, Righi V, Mindrinos MN, Khan N, Swartz HM, Szeto HH, Tompkins RG, Rahme LG, Tzika AA.

Int J Mol Med. 2016 Feb;37(2):299-308. doi: 10.3892/ijmm.2015.2426. Epub 2015 Dec 8.

26.

Early leukocyte gene expression associated with age, burn size, and inhalation injury in severely burned adults.

Sood RF, Gibran NS, Arnoldo BD, Gamelli RL, Herndon DN, Tompkins RG; Inflammation the Host Response to Injury Investigators.

J Trauma Acute Care Surg. 2016 Feb;80(2):250-7. doi: 10.1097/TA.0000000000000905.

27.

Kidney and Liver Injuries After Major Burns in Rats Are Prevented by Resolvin D2.

Inoue Y, Yu YM, Kurihara T, Vasilyev A, Ibrahim A, Oklu R, Zhao G, Nair AV, Brown D, Fischman AJ, Tompkins RG, Irimia D.

Crit Care Med. 2016 May;44(5):e241-52. doi: 10.1097/CCM.0000000000001397.

28.

Gene Expression of Proresolving Lipid Mediator Pathways Is Associated With Clinical Outcomes in Trauma Patients.

Orr SK, Butler KL, Hayden D, Tompkins RG, Serhan CN, Irimia D.

Crit Care Med. 2015 Dec;43(12):2642-50. doi: 10.1097/CCM.0000000000001312.

29.

Is Real-Time Feedback of Burn-Specific Patient-Reported Outcome Measures in Clinical Settings Practical and Useful? A Pilot Study Implementing the Young Adult Burn Outcome Questionnaire.

Ryan CM, Lee AF, Kazis LE, Shapiro GD, Schneider JC, Goverman J, Fagan SP, Wang C, Kim J, Sheridan RL, Tompkins RG.

J Burn Care Res. 2016 Jan-Feb;37(1):64-74. doi: 10.1097/BCR.0000000000000287.

PMID:
26284638
30.

Sulfur mustard gas exposure: case report and review of the literature.

Goverman J, Montecino R, Ibrahim A, Sarhane KA, Tompkins RG, Fagan SP.

Ann Burns Fire Disasters. 2014 Sep 30;27(3):146-50.

31.

Do standard burn mortality formulae work on a population of severely burned children and adults?

Tsurumi A, Que YA, Yan S, Tompkins RG, Rahme LG, Ryan CM.

Burns. 2015 Aug;41(5):935-45. doi: 10.1016/j.burns.2015.03.017. Epub 2015 Apr 25.

PMID:
25922299
32.

Genomics of injury: The Glue Grant experience.

Tompkins RG.

J Trauma Acute Care Surg. 2015 Apr;78(4):671-86. doi: 10.1097/TA.0000000000000568. No abstract available.

33.

Role of protein farnesylation in burn-induced metabolic derangements and insulin resistance in mouse skeletal muscle.

Nakazawa H, Yamada M, Tanaka T, Kramer J, Yu YM, Fischman AJ, Martyn JA, Tompkins RG, Kaneki M.

PLoS One. 2015 Jan 16;10(1):e0116633. doi: 10.1371/journal.pone.0116633. eCollection 2015.

34.

Morbidity and survival probability in burn patients in modern burn care.

Jeschke MG, Pinto R, Kraft R, Nathens AB, Finnerty CC, Gamelli RL, Gibran NS, Klein MB, Arnoldo BD, Tompkins RG, Herndon DN; Inflammation and the Host Response to Injury Collaborative Research Program.

Crit Care Med. 2015 Apr;43(4):808-15. doi: 10.1097/CCM.0000000000000790.

35.

Mice are not men.

Warren HS, Tompkins RG, Moldawer LL, Seok J, Xu W, Mindrinos MN, Maier RV, Xiao W, Davis RW.

Proc Natl Acad Sci U S A. 2015 Jan 27;112(4):E345. doi: 10.1073/pnas.1414857111. Epub 2014 Dec 24. No abstract available.

36.

Recovery trajectories after burn injury in young adults: does burn size matter?

Ryan CM, Lee A, Kazis LE, Schneider JC, Shapiro GD, Sheridan RL, Meyer WJ, Palmieri T, Pidcock FS, Reilly D, Tompkins RG; Multicenter Burn Outcome Group.

J Burn Care Res. 2015 Jan-Feb;36(1):118-29. doi: 10.1097/BCR.0000000000000214.

PMID:
25501787
37.

Spontaneous neutrophil migration patterns during sepsis after major burns.

Jones CN, Moore M, Dimisko L, Alexander A, Ibrahim A, Hassell BA, Warren HS, Tompkins RG, Fagan SP, Irimia D.

PLoS One. 2014 Dec 9;9(12):e114509. doi: 10.1371/journal.pone.0114509. eCollection 2014.

38.

Treatment of heterotopic ossification through remote ATP hydrolysis.

Peterson JR, De La Rosa S, Eboda O, Cilwa KE, Agarwal S, Buchman SR, Cederna PS, Xi C, Morris MD, Herndon DN, Xiao W, Tompkins RG, Krebsbach PH, Wang SC, Levi B.

Sci Transl Med. 2014 Sep 24;6(255):255ra132. doi: 10.1126/scitranslmed.3008810.

39.

Single hind limb burn injury to mice alters nuclear factor-κB expression and [¹⁸F] 2-fluoro-2-deoxy-D-glucose uptake.

Carter EA, Hamrahi V, Paul K, Bonab AA, Jung W, Tompkins RG, Fischman AJ.

J Burn Care Res. 2014 Nov-Dec;35(6):e373-8. doi: 10.1097/BCR.0000000000000035.

40.

On the horizon: research priorities in burns for the next decade.

Wolf SE, Tompkins RG, Herndon DN.

Surg Clin North Am. 2014 Aug;94(4):917-30. doi: 10.1016/j.suc.2014.05.012. Epub 2014 Jun 16. Review.

PMID:
25085097
41.

Simvastatin reduces burn injury-induced splenic apoptosis via downregulation of the TNF-α/NF-κB pathway.

Zhao G, Yu YM, Kaneki M, Bonab AA, Tompkins RG, Fischman AJ.

Ann Surg. 2015 May;261(5):1006-12. doi: 10.1097/SLA.0000000000000764.

42.

Prediction of multiple infections after severe burn trauma: a prospective cohort study.

Yan S, Tsurumi A, Que YA, Ryan CM, Bandyopadhaya A, Morgan AA, Flaherty PJ, Tompkins RG, Rahme LG.

Ann Surg. 2015 Apr;261(4):781-92. doi: 10.1097/SLA.0000000000000759.

43.

Detecting differential protein expression in large-scale population proteomics.

Ryu SY, Qian WJ, Camp DG, Smith RD, Tompkins RG, Davis RW, Xiao W.

Bioinformatics. 2014 Oct;30(19):2741-6. doi: 10.1093/bioinformatics/btu341. Epub 2014 Jun 12.

44.

In vivo high-resolution magic angle spinning proton NMR spectroscopy of Drosophila melanogaster flies as a model system to investigate mitochondrial dysfunction in Drosophila GST2 mutants.

Righi V, Apidianakis Y, Psychogios N, Rahme LG, Tompkins RG, Tzika AA.

Int J Mol Med. 2014 Jul;34(1):327-33. doi: 10.3892/ijmm.2014.1757. Epub 2014 Apr 24.

PMID:
24789699
45.

Benchmarking outcomes in the critically injured burn patient.

Klein MB, Goverman J, Hayden DL, Fagan SP, McDonald-Smith GP, Alexander AK, Gamelli RL, Gibran NS, Finnerty CC, Jeschke MG, Arnoldo B, Wispelwey B, Mindrinos MN, Xiao W, Honari SE, Mason PH, Schoenfeld DA, Herndon DN, Tompkins RG; Inflammation and Host Response to Injury, and Large-Scale Collaborative Research Program.

Ann Surg. 2014 May;259(5):833-41. doi: 10.1097/SLA.0000000000000438.

46.

Survival from burns in the new millennium: 70 years' experience from a single institution.

Tompkins RG.

Ann Surg. 2015 Feb;261(2):263-8. doi: 10.1097/SLA.0000000000000623. Review.

47.

Membrane potential-dependent uptake of 18F-triphenylphosphonium--a new voltage sensor as an imaging agent for detecting burn-induced apoptosis.

Zhao G, Yu YM, Shoup TM, Elmaleh DR, Bonab AA, Tompkins RG, Fischman AJ.

J Surg Res. 2014 May 15;188(2):473-9. doi: 10.1016/j.jss.2014.01.011. Epub 2014 Jan 11.

48.

Long-term posttraumatic stress symptoms vary inversely with early opiate dosing in children recovering from serious burns: effects durable at 4 years.

Sheridan RL, Stoddard FJ, Kazis LE, Lee A, Li NC, Kagan RJ, Palmieri TL, Meyer WJ 3rd, Nicolai M, Stubbs TK, Chan G, Hinson MI, Herndon DN, Tompkins RG; Multi-Center Benchmarking Study.

J Trauma Acute Care Surg. 2014 Mar;76(3):828-32. doi: 10.1097/TA.0b013e3182ab111c.

PMID:
24553556
49.

Effect of exercise on burn-induced changes in tissue-specific glucose metabolism.

Carter EA, Paul K, Bonab AA, Tompkins RG, Fischman AJ.

J Burn Care Res. 2014 Nov-Dec;35(6):470-3. doi: 10.1097/BCR.0000000000000036.

50.

Reply to Osterburg et al.: To study human inflammatory diseases in humans.

Tompkins RG, Warren HS, Mindrinos MN, Xiao W, Davis RW.

Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):E3371. No abstract available.

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