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Items: 1 to 50 of 165

1.

Collagen XVIII Deposition in the Basement Membrane Zone beneath the Newly Forming Epidermis during Wound Healing in Mice.

Maeba T, Yonezawa T, Ono M, Tomono Y, Heljasvaara R, Pihlajaniemi T, Inagawa K, Oohashi T.

Acta Med Okayama. 2019 Apr;73(2):135-146. doi: 10.18926/AMO/56649.

2.

A Novel Combination Cancer Therapy with Iron Chelator Targeting Cancer Stem Cells via Suppressing Stemness.

Katsura Y, Ohara T, Noma K, Ninomiya T, Kashima H, Kato T, Sato H, Komoto S, Narusaka T, Tomono Y, Xing B, Chen Y, Tazawa H, Kagawa S, Shirakawa Y, Kasai T, Seno M, Matsukawa A, Fujiwara T.

Cancers (Basel). 2019 Feb 3;11(2). pii: E177. doi: 10.3390/cancers11020177.

3.

Biallelic COLGALT1 variants are associated with cerebral small vessel disease.

Miyatake S, Schneeberger S, Koyama N, Yokochi K, Ohmura K, Shiina M, Mori H, Koshimizu E, Imagawa E, Uchiyama Y, Mitsuhashi S, Frith MC, Fujita A, Satoh M, Taguri M, Tomono Y, Takahashi K, Doi H, Takeuchi H, Nakashima M, Mizuguchi T, Takata A, Miyake N, Saitsu H, Tanaka F, Ogata K, Hennet T, Matsumoto N.

Ann Neurol. 2018 Dec;84(6):843-853. doi: 10.1002/ana.25367. Epub 2018 Nov 30.

PMID:
30412317
4.

Hair follicle epidermal stem cells define a niche for tactile sensation.

Cheng CC, Tsutsui K, Taguchi T, Sanzen N, Nakagawa A, Kakiguchi K, Yonemura S, Tanegashima C, Keeley SD, Kiyonari H, Furuta Y, Tomono Y, Watt FM, Fujiwara H.

Elife. 2018 Oct 25;7. pii: e38883. doi: 10.7554/eLife.38883.

5.

A novel, nontoxic iron chelator, super-polyphenol, effectively induces apoptosis in human cancer cell lines.

Ohara T, Tomono Y, Boyi X, Yingfu S, Omori K, Matsukawa A.

Oncotarget. 2018 Aug 28;9(67):32751-32760. doi: 10.18632/oncotarget.25973. eCollection 2018 Aug 28.

6.

Regulation of keratin 5/14 intermediate filaments by CDK1, Aurora-B, and Rho-kinase.

Inaba H, Yamakawa D, Tomono Y, Enomoto A, Mii S, Kasahara K, Goto H, Inagaki M.

Biochem Biophys Res Commun. 2018 Apr 6;498(3):544-550. doi: 10.1016/j.bbrc.2018.03.016. Epub 2018 Mar 6.

7.

Iron depletion is a novel therapeutic strategy to target cancer stem cells.

Ninomiya T, Ohara T, Noma K, Katsura Y, Katsube R, Kashima H, Kato T, Tomono Y, Tazawa H, Kagawa S, Shirakawa Y, Kimura F, Chen L, Kasai T, Seno M, Matsukawa A, Fujiwara T.

Oncotarget. 2017 Oct 12;8(58):98405-98416. doi: 10.18632/oncotarget.21846. eCollection 2017 Nov 17.

8.

The specific localization of advanced glycation end-products (AGEs) in rat pancreatic islets.

Morioka Y, Teshigawara K, Tomono Y, Wang D, Izushi Y, Wake H, Liu K, Takahashi HK, Mori S, Nishibori M.

J Pharmacol Sci. 2017 Aug;134(4):218-224. doi: 10.1016/j.jphs.2017.07.005. Epub 2017 Aug 11.

9.

Monoclonal Suncus Antibodies: Generation of Fusion Partners to Produce Suncus-Suncus Hybridomas.

Sado Y, Inoue S, Tomono Y, Matsuyama M, Fukushima M, Oohashi T, Jogahara T, Oda SI.

Acta Histochem Cytochem. 2017 Apr 27;50(2):71-84. doi: 10.1267/ahc.17007. Epub 2017 Apr 15.

10.

Age and sex differences in serum adiponectin and its association with lipoprotein fractions.

Tomono Y, Hiraishi C, Yoshida H.

Ann Clin Biochem. 2018 Jan;55(1):165-171. doi: 10.1177/0004563217699233. Epub 2017 May 15.

PMID:
28504609
11.

Population Pharmacokinetics of Eplerenone in Japanese Patients With Chronic Heart Failure.

Oishi M, Tomono Y, Zhao Q, Sweeney K.

J Clin Pharmacol. 2017 Jun;57(6):730-738. doi: 10.1002/jcph.861. Epub 2016 Dec 29.

PMID:
28032902
12.

Desmin phosphorylation by Cdk1 is required for efficient separation of desmin intermediate filaments in mitosis and detected in murine embryonic/newborn muscle and human rhabdomyosarcoma tissues.

Makihara H, Inaba H, Enomoto A, Tanaka H, Tomono Y, Ushida K, Goto M, Kurita K, Nishida Y, Kasahara K, Goto H, Inagaki M.

Biochem Biophys Res Commun. 2016 Sep 23;478(3):1323-9. doi: 10.1016/j.bbrc.2016.08.122. Epub 2016 Aug 23.

13.

Iron depletion-induced downregulation of N-cadherin expression inhibits invasive malignant phenotypes in human esophageal cancer.

Nishitani S, Noma K, Ohara T, Tomono Y, Watanabe S, Tazawa H, Shirakawa Y, Fujiwara T.

Int J Oncol. 2016 Oct;49(4):1351-9. doi: 10.3892/ijo.2016.3640. Epub 2016 Jul 29.

PMID:
27499208
14.

Population pharmacokinetic modelling of factor IX activity after administration of recombinant factor IX in patients with haemophilia B.

Suzuki A, Tomono Y, Korth-Bradley JM.

Haemophilia. 2016 Sep;22(5):e359-66. doi: 10.1111/hae.12969. Epub 2016 Jun 28.

PMID:
27353956
15.

Morning Home Blood Pressure Is a Strong Predictor of Coronary Artery Disease: The HONEST Study.

Kario K, Saito I, Kushiro T, Teramukai S, Tomono Y, Okuda Y, Shimada K.

J Am Coll Cardiol. 2016 Apr 5;67(13):1519-1527. doi: 10.1016/j.jacc.2016.01.037.

16.

Iron depletion enhances the effect of sorafenib in hepatocarcinoma.

Urano S, Ohara T, Noma K, Katsube R, Ninomiya T, Tomono Y, Tazawa H, Kagawa S, Shirakawa Y, Kimura F, Nouso K, Matsukawa A, Yamamoto K, Fujiwara T.

Cancer Biol Ther. 2016 Jun 2;17(6):648-56. doi: 10.1080/15384047.2016.1177677. Epub 2016 Apr 18.

17.

Oxidative stress balance is dysregulated and represents an additional target for treating cholangiocarcinoma.

Uchida D, Takaki A, Ishikawa H, Tomono Y, Kato H, Tsutsumi K, Tamaki N, Maruyama T, Tomofuji T, Tsuzaki R, Yasunaka T, Koike K, Matsushita H, Ikeda F, Miyake Y, Shiraha H, Nouso K, Yoshida R, Umeda Y, Shinoura S, Yagi T, Fujiwara T, Morita M, Fukushima M, Yamamoto K, Okada H.

Free Radic Res. 2016 Jul;50(7):732-43. doi: 10.3109/10715762.2016.1172071. Epub 2016 Apr 25.

PMID:
27021847
18.

Ectodomain Shedding of Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE-1) Is Induced by Vascular Endothelial Growth Factor A (VEGF-A).

Nishida-Fukuda H, Araki R, Shudou M, Okazaki H, Tomono Y, Nakayama H, Fukuda S, Sakaue T, Shirakata Y, Sayama K, Hashimoto K, Detmar M, Higashiyama S, Hirakawa S.

J Biol Chem. 2016 May 13;291(20):10490-500. doi: 10.1074/jbc.M115.683201. Epub 2016 Mar 10.

19.

[Differences in Measured Values among Homogenous Assay Reagents of LDL-C in LP-X Positive Serum Samples].

Abe M, Kurosawa H, Sato R, Ito K, Tomono Y, Manita D, Hirowatari Y, Yoshida H.

Rinsho Byori. 2015 Mar;63(3):312-8. Japanese.

PMID:
26524853
20.

Population pharmacokinetic analysis of voriconazole from a pharmacokinetic study with immunocompromised Japanese pediatric subjects.

Muto C, Shoji S, Tomono Y, Liu P.

Antimicrob Agents Chemother. 2015;59(6):3216-23. doi: 10.1128/AAC.04993-14. Epub 2015 Mar 23.

21.

Clinical relevance of decreased ratios of serum eicosapentaenoic acid/arachidonic acid (AA) and docosahexaenoic acid/AA to impaired arterial stiffness.

Yoshida H, Ito K, Sato R, Kurosawa H, Tomono Y, Hirowatari Y, Shimizu M, Tada N.

Int J Cardiol. 2014 Dec 15;177(2):517-9. doi: 10.1016/j.ijcard.2014.08.093. Epub 2014 Aug 23. No abstract available.

PMID:
25192787
22.

Population pharmacokinetics of the 5-hydroxymethyl metabolite of tolterodine after administration of fesoterodine sustained release tablet in Western and East Asian populations.

Oishi M, Tomono Y, Yamagami H, Malhotra B.

J Clin Pharmacol. 2014 Aug;54(8):928-36. doi: 10.1002/jcph.274. Epub 2014 Mar 21.

PMID:
24619889
23.

Population pharmacokinetics of ampicillin and sulbactam in patients with community-acquired pneumonia: evaluation of the impact of renal impairment.

Soto E, Shoji S, Muto C, Tomono Y, Marshall S.

Br J Clin Pharmacol. 2014 Mar;77(3):509-21. doi: 10.1111/bcp.12232.

24.

Inhibition of the growth factor MDK/midkine by a novel small molecule compound to treat non-small cell lung cancer.

Hao H, Maeda Y, Fukazawa T, Yamatsuji T, Takaoka M, Bao XH, Matsuoka J, Okui T, Shimo T, Takigawa N, Tomono Y, Nakajima M, Fink-Baldauf IM, Nelson S, Seibel W, Papoian R, Whitsett JA, Naomoto Y.

PLoS One. 2013 Aug 16;8(8):e71093. doi: 10.1371/journal.pone.0071093. eCollection 2013.

25.

Correlation between the characteristics of acceleration and visco elasticity of artery wall under pulsatile flow conditions (physical meaning of I* as a parameter of progressive behaviors of atherosclerosis and arteriosclerosis).

Yokobori AT Jr, Ohmi T, Monma R, Tomono Y, Inoue K, Owa M, Ichiki M, Mochizuki N, Yamashita H.

Biomed Mater Eng. 2013;23(1-2):75-91. doi: 10.3233/BME-120734.

PMID:
23442239
26.

Antiproliferative effect of a novel mTOR inhibitor temsirolimus contributes to the prolonged survival of orthotopic esophageal cancer-bearing mice.

Nishikawa T, Takaoka M, Ohara T, Tomono Y, Hao H, Bao X, Fukazawa T, Wang Z, Sakurama K, Fujiwara Y, Motoki T, Shirakawa Y, Yamatsuji T, Tanaka N, Fujiwara T, Naomoto Y.

Cancer Biol Ther. 2013 Mar;14(3):230-6. doi: 10.4161/cbt.23294. Epub 2013 Jan 4.

27.

A novel synergistic effect of iron depletion on antiangiogenic cancer therapy.

Ohara T, Noma K, Urano S, Watanabe S, Nishitani S, Tomono Y, Kimura F, Kagawa S, Shirakawa Y, Fujiwara T.

Int J Cancer. 2013 Jun 1;132(11):2705-13. doi: 10.1002/ijc.27943. Epub 2012 Dec 4.

28.

Predictors, including blood, urine, anthropometry, and nutritional indices, of all-cause mortality among institutionalized individuals with intellectual disability.

Ohwada H, Nakayama T, Tomono Y, Yamanaka K.

Res Dev Disabil. 2013 Jan;34(1):650-5. doi: 10.1016/j.ridd.2012.10.006. Epub 2012 Nov 1.

PMID:
23123878
29.

Oral administration of FAK inhibitor TAE226 inhibits the progression of peritoneal dissemination of colorectal cancer.

Hao HF, Takaoka M, Bao XH, Wang ZG, Tomono Y, Sakurama K, Ohara T, Fukazawa T, Yamatsuji T, Fujiwara T, Naomoto Y.

Biochem Biophys Res Commun. 2012 Jul 13;423(4):744-9. doi: 10.1016/j.bbrc.2012.06.030. Epub 2012 Jun 13.

30.

Different truncation methods of AUC between Japan and the EU for bioequivalence assessment: influence on the regulatory judgment.

Oishi M, Chiba K, Fukushima T, Tomono Y, Suwa T.

Drug Metab Pharmacokinet. 2012;27(6):658-62. Epub 2012 May 22.

31.

In vivo experiments of a surgical robot with vision field control for Single Port Endoscopic Surgery.

Sekiguchi Y, Kobayashi Y, Watanabe H, Tomono Y, Noguchi T, Takahashi Y, Toyoda K, Uemura M, Ieiri S, Ohdaira T, Tomikawa M, Hashizume M, Fujie MG.

Conf Proc IEEE Eng Med Biol Soc. 2011;2011:7045-8. doi: 10.1109/IEMBS.2011.6091781.

PMID:
22255961
32.

Gene expression and localization of high-mobility group box chromosomal protein-1 (HMGB-1)in human osteoarthritic cartilage.

Terada C, Yoshida A, Nasu Y, Mori S, Tomono Y, Tanaka M, Takahashi HK, Nishibori M, Ozaki T, Nishida K.

Acta Med Okayama. 2011 Dec;65(6):369-77.

33.

Frequency response of blood vessel wall with atherosclerosis and aneurysm.

Yokobori AT Jr, Ichiki M, Tomono Y, Tanaka D, Kanno T, Sugiura R, Ohtomo Y, Ito M, Ohgoshi S.

Biomed Mater Eng. 2011;21(3):171-7. doi: 10.3233/BME-2011-0666.

PMID:
22072081
34.

Inhibition of mTOR by temsirolimus contributes to prolonged survival of mice with pleural dissemination of non-small-cell lung cancer cells.

Ohara T, Takaoka M, Toyooka S, Tomono Y, Nishikawa T, Shirakawa Y, Yamatsuji T, Tanaka N, Fujiwara T, Naomoto Y.

Cancer Sci. 2011 Jul;102(7):1344-9. doi: 10.1111/j.1349-7006.2011.01967.x. Epub 2011 Jun 2.

35.

Glutamine depletion induces murine neonatal melena with increased apoptosis of the intestinal epithelium.

Motoki T, Naomoto Y, Hoshiba J, Shirakawa Y, Yamatsuji T, Matsuoka J, Takaoka M, Tomono Y, Fujiwara Y, Tsuchita H, Gunduz M, Nagatsuka H, Tanaka N, Fujiwara T.

World J Gastroenterol. 2011 Feb 14;17(6):717-26. doi: 10.3748/wjg.v17.i6.717.

36.

Population pharmacokinetics of pregabalin in healthy subjects and patients with post-herpetic neuralgia or diabetic peripheral neuropathy.

Shoji S, Suzuki M, Tomono Y, Bockbrader HN, Matsui S.

Br J Clin Pharmacol. 2011 Jul;72(1):63-76. doi: 10.1111/j.1365-2125.2011.03932.x.

37.

Design of a surgical robot with dynamic vision field control for Single Port Endoscopic Surgery.

Kobayashi Y, Sekiguchi Y, Tomono Y, Watanabe H, Toyoda K, Konishi K, Tomikawa M, Ieiri S, Tanoue K, Hashizume M, Fujie MG.

Conf Proc IEEE Eng Med Biol Soc. 2010;2010:979-83. doi: 10.1109/IEMBS.2010.5627615.

PMID:
21096985
38.

[A new anti-mycobacterial agent, rifabutin].

Kurashima A, Mori T, Tomono Y, Abe S, Nagaoka M, Abe M.

Kekkaku. 2010 Oct;85(10):743-56. Review. Japanese.

PMID:
21061564
39.

A surgical robot with vision field control for single port endoscopic surgery.

Kobayashi Y, Tomono Y, Sekiguchi Y, Watanabe H, Toyoda K, Konishi K, Tomikawa M, Ieiri S, Tanoue K, Hashizume M, Fujie MG.

Int J Med Robot. 2010 Dec;6(4):454-64. doi: 10.1002/rcs.355. Epub 2010 Oct 14.

PMID:
20949430
40.

14-3-3gamma mediates Cdc25A proteolysis to block premature mitotic entry after DNA damage.

Kasahara K, Goto H, Enomoto M, Tomono Y, Kiyono T, Inagaki M.

EMBO J. 2010 Aug 18;29(16):2802-12. doi: 10.1038/emboj.2010.157. Epub 2010 Jul 16.

41.

Study on the water structure and blood compatibility of poly(acryloylmorpholine-r-butyl methacrylate).

Mochizuki A, Kimura M, Ina A, Tomono Y, Tanaka M.

J Biomater Sci Polym Ed. 2010;21(14):1895-910. doi: 10.1163/092050610X489321. Epub 2010 Jun 21.

PMID:
20566050
42.

Direct renin inhibition improved insulin resistance and adipose tissue dysfunction in type 2 diabetic KK-A(y) mice.

Iwai M, Kanno H, Tomono Y, Inaba S, Senba I, Furuno M, Mogi M, Horiuchi M.

J Hypertens. 2010 Jul;28(7):1471-81. doi: 10.1097/HJH.0b013e32833bc420.

PMID:
20543712
43.

HSP90 and its inhibitors.

Hao H, Naomoto Y, Bao X, Watanabe N, Sakurama K, Noma K, Motoki T, Tomono Y, Fukazawa T, Shirakawa Y, Yamatsuji T, Matsuoka J, Takaoka M.

Oncol Rep. 2010 Jun;23(6):1483-92. Review.

PMID:
20428801
44.

Autophagy: Can it become a potential therapeutic target?

Bao XH, Naomoto Y, Hao HF, Watanabe N, Sakurama K, Noma K, Motoki T, Tomono Y, Fukazawa T, Shirakawa Y, Yamatsuji T, Matsuoka J, Takaoka M.

Int J Mol Med. 2010 Apr;25(4):493-503. Review.

PMID:
20198296
45.

[Therapeutic application of diacylglycerol oil for the metabolic syndrome].

Yanai H, Tomono Y, Yoshida H, Tada N.

Rinsho Byori. 2010 Jan;58(1):39-44. Review. Japanese.

PMID:
20169943
46.

IGF-IR and its inhibitors in gastrointestinal carcinomas (Review).

Bao XH, Naomoto Y, Hao HF, Watanabe N, Sakurama K, Noma K, Motoki T, Tomono Y, Fukazawa T, Shirakawa Y, Yamatsuji T, Matsuoka J, Takaoka M.

Oncol Lett. 2010 Jan;1(1):195-201. Epub 2010 Jan 1.

47.

A molecular mechanism for diacylglycerol-mediated promotion of negative caloric balance.

Yanai H, Tomono Y, Ito K, Hirowatari Y, Yoshida H, Tada N.

Diabetes Metab Syndr Obes. 2009 Dec 18;3:1-6.

48.

Progress in researches about focal adhesion kinase in gastrointestinal tract.

Hao HF, Naomoto Y, Bao XH, Watanabe N, Sakurama K, Noma K, Tomono Y, Fukazawa T, Shirakawa Y, Yamatsuji T, Matsuoka J, Takaoka M.

World J Gastroenterol. 2009 Dec 21;15(47):5916-23. Review.

49.

Administration of natural astaxanthin increases serum HDL-cholesterol and adiponectin in subjects with mild hyperlipidemia.

Yoshida H, Yanai H, Ito K, Tomono Y, Koikeda T, Tsukahara H, Tada N.

Atherosclerosis. 2010 Apr;209(2):520-3. doi: 10.1016/j.atherosclerosis.2009.10.012. Epub 2009 Oct 14.

PMID:
19892350
50.

Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition.

Enomoto M, Goto H, Tomono Y, Kasahara K, Tsujimura K, Kiyono T, Inagaki M.

J Biol Chem. 2009 Dec 4;284(49):34223-30. doi: 10.1074/jbc.C109.051540. Epub 2009 Oct 16.

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