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Items: 32


Transcriptionally dynamic progenitor populations organised around a stable niche drive axial patterning.

Wymeersch FJ, Skylaki S, Huang Y, Watson JA, Economou C, Marek-Johnston C, Tomlinson SR, Wilson V.

Development. 2019 Jan 2;146(1). pii: dev168161. doi: 10.1242/dev.168161.


CpG binding protein (CFP1) occupies open chromatin regions of active genes, including enhancers and non-CpG islands.

van de Lagemaat LN, Flenley M, Lynch MD, Garrick D, Tomlinson SR, Kranc KR, Vernimmen D.

Epigenetics Chromatin. 2018 Oct 6;11(1):59. doi: 10.1186/s13072-018-0230-0.


Esrrb extinction triggers dismantling of naïve pluripotency and marks commitment to differentiation.

Festuccia N, Halbritter F, Corsinotti A, Gagliardi A, Colby D, Tomlinson SR, Chambers I.

EMBO J. 2018 Nov 2;37(21). pii: e95476. doi: 10.15252/embj.201695476. Epub 2018 Oct 1.


Mapping transcription factor occupancy using minimal numbers of cells in vitro and in vivo.

Tosti L, Ashmore J, Tan BSN, Carbone B, Mistri TK, Wilson V, Tomlinson SR, Kaji K.

Genome Res. 2018 Apr;28(4):592-605. doi: 10.1101/gr.227124.117. Epub 2018 Mar 23.


A molecular roadmap of the AGM region reveals BMPER as a novel regulator of HSC maturation.

McGarvey AC, Rybtsov S, Souilhol C, Tamagno S, Rice R, Hills D, Godwin D, Rice D, Tomlinson SR, Medvinsky A.

J Exp Med. 2017 Dec 4;214(12):3731-3751. doi: 10.1084/jem.20162012. Epub 2017 Nov 1.


Selective influence of Sox2 on POU transcription factor binding in embryonic and neural stem cells.

Mistri TK, Devasia AG, Chu LT, Ng WP, Halbritter F, Colby D, Martynoga B, Tomlinson SR, Chambers I, Robson P, Wohland T.

EMBO Rep. 2015 Sep;16(9):1177-91. doi: 10.15252/embr.201540467. Epub 2015 Aug 11.


Novel Human Embryonic Stem Cell Regulators Identified by Conserved and Distinct CpG Island Methylation State.

Pells S, Koutsouraki E, Morfopoulou S, Valencia-Cadavid S, Tomlinson SR, Kalathur R, Futschik ME, De Sousa PA.

PLoS One. 2015 Jul 7;10(7):e0131102. doi: 10.1371/journal.pone.0131102. eCollection 2015.


Reprogramming diminishes retention of Mycobacterium leprae in Schwann cells and elevates bacterial transfer property to fibroblasts.

Masaki T, McGlinchey A, Tomlinson SR, Qu J, Rambukkana A.

Version 3. F1000Res. 2013 Sep 25 [revised 2013 Jan 1];2:198. doi: 10.12688/f1000research.2-198.v3. eCollection 2013.


Innate immune response precedes Mycobacterium leprae-induced reprogramming of adult Schwann cells.

Masaki T, McGlinchey A, Cholewa-Waclaw J, Qu J, Tomlinson SR, Rambukkana A.

Cell Reprogram. 2014 Feb;16(1):9-17. doi: 10.1089/cell.2013.0064. Epub 2013 Nov 26.


GeneProf data: a resource of curated, integrated and reusable high-throughput genomics experiments.

Halbritter F, Kousa AI, Tomlinson SR.

Nucleic Acids Res. 2014 Jan;42(Database issue):D851-8. doi: 10.1093/nar/gkt966. Epub 2013 Oct 29.


A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.

Gagliardi A, Mullin NP, Ying Tan Z, Colby D, Kousa AI, Halbritter F, Weiss JT, Felker A, Bezstarosti K, Favaro R, Demmers J, Nicolis SK, Tomlinson SR, Poot RA, Chambers I.

EMBO J. 2013 Aug 14;32(16):2231-47. doi: 10.1038/emboj.2013.161. Epub 2013 Jul 26.


Tuning of β-catenin activity is required to stabilize self-renewal of rat embryonic stem cells.

Meek S, Wei J, Sutherland L, Nilges B, Buehr M, Tomlinson SR, Thomson AJ, Burdon T.

Stem Cells. 2013 Oct;31(10):2104-15. doi: 10.1002/stem.1466.


High-resolution analysis with novel cell-surface markers identifies routes to iPS cells.

O'Malley J, Skylaki S, Iwabuchi KA, Chantzoura E, Ruetz T, Johnsson A, Tomlinson SR, Linnarsson S, Kaji K.

Nature. 2013 Jul 4;499(7456):88-91. doi: 10.1038/nature12243. Epub 2013 Jun 2.


Reduced Oct4 expression directs a robust pluripotent state with distinct signaling activity and increased enhancer occupancy by Oct4 and Nanog.

Karwacki-Neisius V, Göke J, Osorno R, Halbritter F, Ng JH, Weiße AY, Wong FC, Gagliardi A, Mullin NP, Festuccia N, Colby D, Tomlinson SR, Ng HH, Chambers I.

Cell Stem Cell. 2013 May 2;12(5):531-45. doi: 10.1016/j.stem.2013.04.023.


Dynamics of thymus organogenesis and colonization in early human development.

Farley AM, Morris LX, Vroegindeweij E, Depreter ML, Vaidya H, Stenhouse FH, Tomlinson SR, Anderson RA, Cupedo T, Cornelissen JJ, Blackburn CC.

Development. 2013 May;140(9):2015-26. doi: 10.1242/dev.087320.


Esrrb is a direct Nanog target gene that can substitute for Nanog function in pluripotent cells.

Festuccia N, Osorno R, Halbritter F, Karwacki-Neisius V, Navarro P, Colby D, Wong F, Yates A, Tomlinson SR, Chambers I.

Cell Stem Cell. 2012 Oct 5;11(4):477-90. doi: 10.1016/j.stem.2012.08.002.


Recurrent transcriptional clusters in the genome of mouse pluripotent stem cells.

Skylaki S, Tomlinson SR.

Nucleic Acids Res. 2012 Oct;40(19):e153. doi: 10.1093/nar/gks663. Epub 2012 Jul 12.


GeneProf: analysis of high-throughput sequencing experiments.

Halbritter F, Vaidya HJ, Tomlinson SR.

Nat Methods. 2011 Dec 28;9(1):7-8. doi: 10.1038/nmeth.1809. No abstract available.


The transcriptional foundation of pluripotency.

Chambers I, Tomlinson SR.

Development. 2009 Jul;136(14):2311-22. doi: 10.1242/dev.024398. Review.


Identification of Plet-1 as a specific marker of early thymic epithelial progenitor cells.

Depreter MG, Blair NF, Gaskell TL, Nowell CS, Davern K, Pagliocca A, Stenhouse FH, Farley AM, Fraser A, Vrana J, Robertson K, Morahan G, Tomlinson SR, Blackburn CC.

Proc Natl Acad Sci U S A. 2008 Jan 22;105(3):961-6. doi: 10.1073/pnas.0711170105. Epub 2008 Jan 14.


Hex acts with beta-catenin to regulate anteroposterior patterning via a Groucho-related co-repressor and Nodal.

Zamparini AL, Watts T, Gardner CE, Tomlinson SR, Johnston GI, Brickman JM.

Development. 2006 Sep;133(18):3709-22.


Tissue, cell and stage specificity of (epi)mutations in cancers.

Sieber OM, Tomlinson SR, Tomlinson IP.

Nat Rev Cancer. 2005 Aug;5(8):649-55. Review.


Peroxisome proliferator activated receptor alpha regulates a male-specific cytochrome P450 in mouse liver.

Jeffery B, Choudhury AI, Horley N, Bruce M, Tomlinson SR, Roberts RA, Gray TJ, Barrett DA, Shaw PN, Kendall D, Bell DR.

Arch Biochem Biophys. 2004 Sep 15;429(2):231-6.


Molecular analysis of peroxisome proliferation in the hamster.

Choudhury AI, Sims HM, Horley NJ, Roberts RA, Tomlinson SR, Salter AM, Bruce M, Shaw PN, Kendall D, Barrett DA, Bell DR.

Toxicol Appl Pharmacol. 2004 May 15;197(1):9-18.


Latrophilin is required for toxicity of black widow spider venom in Caenorhabditis elegans.

Mee CJ, Tomlinson SR, Perestenko PV, De Pomerai D, Duce IR, Usherwood PN, Bell DR.

Biochem J. 2004 Feb 15;378(Pt 1):185-91.


Interaction of CRP L124 with cAMP affects CRP cAMP binding constants, cAMP binding cooperativity, and CRP allostery.

Tomlinson SR, Tutar Y, Harman JG.

Biochemistry. 2003 Apr 8;42(13):3759-65.


Ethics and evidence-based medicine.

Tomlinson SR.

Med J Aust. 2002 Feb 4;176(3):137; author reply 138. No abstract available.


Amino acid substitution at position 99 affects the rate of CRP subunit exchange.

Baker CH, Tomlinson SR, García AE, Harman JG.

Biochemistry. 2001 Oct 16;40(41):12329-38.


Species differences in peroxisome proliferation; mechanisms and relevance.

Choudhury AI, Chahal S, Bell AR, Tomlinson SR, Roberts RA, Salter AM, Bell DR.

Mutat Res. 2000 Mar 17;448(2):201-12.


Interaction of a polyamine amide wasp toxin with cloned and mutant glutamate receptors.

Tomlinson SR, Kirwin S, Mellor I, Harris J, Mundey M, Brierley M, Bell DR, Usherwood PN.

Biochem Soc Trans. 1997 Aug;25(3):551S. No abstract available.


A novel murine P-450 gene, Cyp4a14, is part of a cluster of Cyp4a and Cyp4b, but not of CYP4F, genes in mouse and humans.

Heng YM, Kuo CS, Jones PS, Savory R, Schulz RM, Tomlinson SR, Gray TJ, Bell DR.

Biochem J. 1997 Aug 1;325 ( Pt 3):741-9.

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