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Food availability before aestivation governs growth and winter reproductive potential in the capital breeding fish, Ammodytes japonicus.

Kuzuhara H, Yoneda M, Tsuzaki T, Takahashi M, Kono N, Tomiyama T.

PLoS One. 2019 Mar 7;14(3):e0213611. doi: 10.1371/journal.pone.0213611. eCollection 2019.


A major isoform of mitochondrial trans-2-enoyl-CoA reductase is dispensable for wax ester production in Euglena gracilis under anaerobic conditions.

Tomiyama T, Goto K, Tanaka Y, Maruta T, Ogawa T, Sawa Y, Ito T, Ishikawa T.

PLoS One. 2019 Jan 16;14(1):e0210755. doi: 10.1371/journal.pone.0210755. eCollection 2019.


Incidentally Detected Amyloid Light-Chain Amyloidosis Caused by Monoclonal Gammopathy of Undetermined Significance: Possible Time-Dependent Change in Colonic Findings.

Fukui T, Tanimura Y, Matsumoto Y, Horitani S, Tomiyama T, Okazaki K.

Case Rep Gastroenterol. 2018 Dec 6;12(3):737-746. doi: 10.1159/000494919. eCollection 2018 Sep-Dec.


Hemophagocytic syndrome after living donor liver transplantation: a case report with a review of the literature.

Iseda N, Yoshizumi T, Toshima T, Morinaga A, Tomiyama T, Takahashi J, Motomura T, Mano Y, Itoh S, Harada N, Ikegami T, Soejima Y.

Surg Case Rep. 2018 Aug 29;4(1):101. doi: 10.1186/s40792-018-0505-5.


Intranasal rifampicin for Alzheimer's disease prevention.

Umeda T, Tanaka A, Sakai A, Yamamoto A, Sakane T, Tomiyama T.

Alzheimers Dement (N Y). 2018 Jul 14;4:304-313. doi: 10.1016/j.trci.2018.06.012. eCollection 2018.


Esophageal Large-Cell Neuroendocrine Carcinoma with Inconsistent Response to Treatment in the Primary and Metastatic Lesions.

Tomiyama T, Orino M, Nakamaru K, Tanaka T, Suzuki R, Okazaki T, Fukata N, Ando Y, Danbara N, Fukui T, Miyasaka C, Okazaki K.

Case Rep Gastroenterol. 2018 May 31;12(2):234-239. doi: 10.1159/000489295. eCollection 2018 May-Aug.


Rivastigmine Improves Appetite by Increasing the Plasma Acyl/Des-Acyl Ghrelin Ratio and Cortisol in Alzheimer Disease.

Furiya Y, Tomiyama T, Izumi T, Ohba N, Ueno S.

Dement Geriatr Cogn Dis Extra. 2018 Mar 13;8(1):77-84. doi: 10.1159/000487358. eCollection 2018 Jan-Apr.


Risk factors for nasal bleeding in patients undergoing transnasal gastrointestinal endoscopy.

Mieda M, Miyashita H, Osawa H, Hirasawa T, Makino N, Toma S, Tomiyama T, Miura Y, Lefor AK, Yamamoto H.

Kaohsiung J Med Sci. 2018 May;34(5):295-300. doi: 10.1016/j.kjms.2017.11.007. Epub 2018 Jan 12.


Mutations in the β-amyloid precursor protein in familial Alzheimer's disease increase Aβ oligomer production in cellular models.

Ohshima Y, Taguchi K, Mizuta I, Tanaka M, Tomiyama T, Kametani F, Yabe-Nishimura C, Mizuno T, Tokuda T.

Heliyon. 2018 Feb 1;4(1):e00511. doi: 10.1016/j.heliyon.2018.e00511. eCollection 2018 Jan.


Feasibility of myocardial flow reserve prediction without the use of dynamic data from myocardial perfusion positron emission tomography.

Hashimoto H, Fukushima Y, Kumita SI, Tomiyama T, Kiriyama T.

Int J Cardiovasc Imaging. 2018 Aug;34(8):1323-1329. doi: 10.1007/s10554-018-1335-z. Epub 2018 Mar 19.


Correction to: Basophils activated via TLR signaling may contribute to pathophysiology of type 1 autoimmune pancreatitis.

Yanagawa M, Uchida K, Ando Y, Tomiyama T, Yamaguchi T, Ikeura T, Fukui T, Nishio A, Uemura Y, Miyara T, Okamoto H, Satoi S, Okazaki K.

J Gastroenterol. 2018 Apr;53(4):582-583. doi: 10.1007/s00535-018-1443-5.


Asymmetric Total Synthesis of (-)-Stemonamine and Its Stereochemical Stability.

Fujita S, Nishikawa K, Iwata T, Tomiyama T, Ikenaga H, Matsumoto K, Shindo M.

Chemistry. 2018 Feb 1;24(7):1539-1543. doi: 10.1002/chem.201706057. Epub 2018 Jan 16.


Wax Ester Synthase/Diacylglycerol Acyltransferase Isoenzymes Play a Pivotal Role in Wax Ester Biosynthesis in Euglena gracilis.

Tomiyama T, Kurihara K, Ogawa T, Maruta T, Ogawa T, Ohta D, Sawa Y, Ishikawa T.

Sci Rep. 2017 Oct 18;7(1):13504. doi: 10.1038/s41598-017-14077-6.


Basophils activated via TLR signaling may contribute to pathophysiology of type 1 autoimmune pancreatitis.

Yanagawa M, Uchida K, Ando Y, Tomiyama T, Yamaguchi T, Ikeura T, Fukui T, Nishio A, Uemura Y, Miyara T, Okamoto H, Satoi S, Okazaki K.

J Gastroenterol. 2018 Mar;53(3):449-460. doi: 10.1007/s00535-017-1390-6. Epub 2017 Sep 18. Erratum in: J Gastroenterol. 2018 Feb 26;:.


Mutation-induced loss of APP function causes GABAergic depletion in recessive familial Alzheimer's disease: analysis of Osaka mutation-knockin mice.

Umeda T, Kimura T, Yoshida K, Takao K, Fujita Y, Matsuyama S, Sakai A, Yamashita M, Yamashita Y, Ohnishi K, Suzuki M, Takuma H, Miyakawa T, Takashima A, Morita T, Mori H, Tomiyama T.

Acta Neuropathol Commun. 2017 Jul 31;5(1):59. doi: 10.1186/s40478-017-0461-5.


Oligomeric amyloid-beta induces MAPK-mediated activation of brain cytosolic and calcium-independent phospholipase A2 in a spatial-specific manner.

Palavicini JP, Wang C, Chen L, Hosang K, Wang J, Tomiyama T, Mori H, Han X.

Acta Neuropathol Commun. 2017 Jul 27;5(1):56. doi: 10.1186/s40478-017-0460-6.


Decreased levels of PDI and P5 in oligodendrocytes in Alzheimer's disease.

Honjo Y, Ayaki T, Tomiyama T, Horibe T, Ito H, Mori H, Takahashi R, Kawakami K.

Neuropathology. 2017 Dec;37(6):495-501. doi: 10.1111/neup.12395. Epub 2017 Jul 21.


Identification of aqueous access residues of the sodium half channel in transmembrane helix 5 of the Fo-a subunit of Propionigenium modestum ATP synthase.

Mitome N, Sato H, Tomiyama T, Shimabukuro K, Matsunishi T, Hamada K, Suzuki T.

Biophys Physicobiol. 2017 Mar 1;14:41-47. doi: 10.2142/biophysico.14.0_41. eCollection 2017.


Multifocal Colonic Wall Abscesses during Anti-Tumor Necrosis Factor (TNF)-α Therapy for a Patient with Ulcerative Colitis: A Very Rare Manifestation of Infectious Complications.

Fukui T, Takahashi M, Okazaki T, Tomiyama T, Fukata N, Ando Y, Okazaki K.

Intern Med. 2017;56(10):1157-1161. doi: 10.2169/internalmedicine.56.8041. Epub 2017 May 15.


Aβ levels in the jugular vein and high molecular weight Aβ oligomer levels in CSF can be used as biomarkers to indicate the anti-amyloid effect of IVIg for Alzheimer's disease.

Kasai T, Kondo M, Ishii R, Tanaka A, Ataka S, Shimada H, Tomiyama T, Mori H, Taylor M, Allsop D, Nakagawa M, Mizuno T, Tokuda T.

PLoS One. 2017 Apr 10;12(4):e0174630. doi: 10.1371/journal.pone.0174630. eCollection 2017.


Morphological and immunohistochemical comparison of intrapancreatic nerves between chronic pancreatitis and type 1 autoimmune pancreatitis.

Kato K, Ikeura T, Yanagawa M, Tomiyama T, Fukui T, Uchida K, Takaoka M, Nishio A, Uemura Y, Satoi S, Yamada H, Okazaki K.

Pancreatology. 2017 May - Jun;17(3):403-410. doi: 10.1016/j.pan.2017.02.009. Epub 2017 Feb 20.


NDR1-Dependent Regulation of Kindlin-3 Controls High-Affinity LFA-1 Binding and Immune Synapse Organization.

Kondo N, Ueda Y, Kita T, Ozawa M, Tomiyama T, Yasuda K, Lim DS, Kinashi T.

Mol Cell Biol. 2017 Mar 31;37(8). pii: e00424-16. doi: 10.1128/MCB.00424-16. Print 2017 Apr 15.


Pediatric Hodgkin lymphoma: biomarkers, drugs, and clinical trials for translational science and medicine.

Nagpal P, Akl MR, Ayoub NM, Tomiyama T, Cousins T, Tai B, Carroll N, Nyrenda T, Bhattacharyya P, Harris MB, Goy A, Pecora A, Suh KS.

Oncotarget. 2016 Oct 11;7(41):67551-67573. doi: 10.18632/oncotarget.11509. Review.


Rifampicin is a candidate preventive medicine against amyloid-β and tau oligomers.

Umeda T, Ono K, Sakai A, Yamashita M, Mizuguchi M, Klein WL, Yamada M, Mori H, Tomiyama T.

Brain. 2016 May;139(Pt 5):1568-86. doi: 10.1093/brain/aww042. Epub 2016 Mar 28.


De novo assembly and comparative transcriptome analysis of Euglena gracilis in response to anaerobic conditions.

Yoshida Y, Tomiyama T, Maruta T, Tomita M, Ishikawa T, Arakawa K.

BMC Genomics. 2016 Mar 3;17:182. doi: 10.1186/s12864-016-2540-6.


Sema3e/Plexin D1 Modulates Immunological Synapse and Migration of Thymocytes by Rap1 Inhibition.

Ueda Y, Kondo N, Ozawa M, Yasuda K, Tomiyama T, Kinashi T.

J Immunol. 2016 Apr 1;196(7):3019-31. doi: 10.4049/jimmunol.1502121. Epub 2016 Feb 26.


Erratum: Intracellular amyloid β oligomers impair organelle transport and induce dendritic spine loss in primary neurons.

Umeda T, Ramser EM, Yamashita M, Nakajima K, Mori H, Silverman MA, Tomiyama T.

Acta Neuropathol Commun. 2016 Jan 28;4:7. doi: 10.1186/s40478-016-0273-z.


The domestic cat as a natural animal model of Alzheimer's disease.

Chambers JK, Tokuda T, Uchida K, Ishii R, Tatebe H, Takahashi E, Tomiyama T, Une Y, Nakayama H.

Acta Neuropathol Commun. 2015 Dec 10;3:78. doi: 10.1186/s40478-015-0258-3.


The modulation of co-stimulatory molecules by circulating exosomes in primary biliary cirrhosis.

Tomiyama T, Yang GX, Zhao M, Zhang W, Tanaka H, Wang J, Leung PS, Okazaki K, He XS, Lu Q, Coppel RL, Bowlus CL, Gershwin ME.

Cell Mol Immunol. 2017 Mar;14(3):276-284. doi: 10.1038/cmi.2015.86. Epub 2015 Sep 21.


Intracellular amyloid β oligomers impair organelle transport and induce dendritic spine loss in primary neurons.

Umeda T, Ramser EM, Yamashita M, Nakajima K, Mori H, Silverman MA, Tomiyama T.

Acta Neuropathol Commun. 2015 Aug 21;3:51. doi: 10.1186/s40478-015-0230-2. Erratum in: Acta Neuropathol Commun. 2016;4:7.


Increased GADD34 in oligodendrocytes in Alzheimer's disease.

Honjo Y, Ayaki T, Tomiyama T, Horibe T, Ito H, Mori H, Takahashi R, Kawakami K.

Neurosci Lett. 2015 Aug 18;602:50-5. doi: 10.1016/j.neulet.2015.06.052. Epub 2015 Jul 2.


Regular budding modes in a zooxanthellate dendrophylliid Turbinaria peltata (Scleractinia) revealed by X-ray CT imaging and three-dimensional reconstruction.

Sentoku A, Ishibashi M, Masumoto S, Ohno R, Tomiyama T, Machiyama H, Tadai O, Ezaki Y.

J Morphol. 2015 Sep;276(9):1100-8. doi: 10.1002/jmor.20402. Epub 2015 Jun 30.


Hypermethylation of MST1 in IgG4-related autoimmune pancreatitis and rheumatoid arthritis.

Fukuhara T, Tomiyama T, Yasuda K, Ueda Y, Ozaki Y, Son Y, Nomura S, Uchida K, Okazaki K, Kinashi T.

Biochem Biophys Res Commun. 2015 Aug 7;463(4):968-74. doi: 10.1016/j.bbrc.2015.06.043. Epub 2015 Jun 6.


Patients with reduced heart rate response to adenosine infusion have low myocardial flow reserve in (13)N-ammonia PET studies.

Tomiyama T, Kumita S, Ishihara K, Suda M, Sakurai M, Hakozaki K, Hashimoto H, Takahashi N, Takano H, Kobayashi Y, Kiriyama T, Fukushima Y, Shimizu W.

Int J Cardiovasc Imaging. 2015 Jun;31(5):1089-95. doi: 10.1007/s10554-015-0654-6. Epub 2015 Apr 7.


Passive immunotherapy of tauopathy targeting pSer413-tau: a pilot study in mice.

Umeda T, Eguchi H, Kunori Y, Matsumoto Y, Taniguchi T, Mori H, Tomiyama T.

Ann Clin Transl Neurol. 2015 Mar;2(3):241-55. doi: 10.1002/acn3.171. Epub 2015 Jan 9.


The reproducibility of time-of-flight PET and conventional PET for the quantification of myocardial blood flow and coronary flow reserve with (13)N-ammonia.

Suda M, Onoguchi M, Tomiyama T, Ishihara K, Takahashi N, Sakurai M, Matsumoto K, Kumita S.

J Nucl Cardiol. 2016 Jun;23(3):457-72. doi: 10.1007/s12350-015-0074-y. Epub 2015 Mar 17.


[Conduct of survey four months after the start of EMR for home visits to promote cooperation between hospitals and clinics].

Nakagawa Y, Sawada S, Tomiyama T, Ueda Y, Fujii K, Takeshita K, Kobayashi M, Isono O.

Gan To Kagaku Ryoho. 2014 Dec;41 Suppl 1:36-8. Japanese.


Immunological potential of cytotoxic T lymphocyte antigen 4 immunoglobulin in murine autoimmune cholangitis.

Tanaka H, Yang GX, Tomiyama T, Tsuneyama K, Zhang W, Leung PS, Coppel RL, Joh T, Nadler SG, Ansari AA, Bowlus C, Gershwin ME.

Clin Exp Immunol. 2015 Jun;180(3):371-82. doi: 10.1111/cei.12581.


Impact of time-of-flight on qualitative and quantitative analyses of myocardial perfusion PET studies using (13)N-ammonia.

Tomiyama T, Ishihara K, Suda M, Kanaya K, Sakurai M, Takahashi N, Takano H, Nitta K, Hakozaki K, Kumita S.

J Nucl Cardiol. 2015 Oct;22(5):998-1007. doi: 10.1007/s12350-014-0037-8. Epub 2014 Dec 3.


Internal skeletal analysis of the colonial azooxanthellate scleractinian Dendrophyllia cribrosa using microfocus X-ray CT images: underlying basis for its rigid and highly adaptive colony structure.

Sentoku A, Morisaki H, Masumoto S, Ohno R, Tomiyama T, Ezaki Y.

J Struct Biol. 2015 Jan;189(1):37-43. doi: 10.1016/j.jsb.2014.11.002. Epub 2014 Nov 20.


Oxygen consumption rate of early pre-antral follicles from vitrified human ovarian cortical tissue.

Ishikawa T, Kyoya T, Nakamura Y, Sato E, Tomiyama T, Kyono K.

J Reprod Dev. 2014;60(6):460-7. doi: 10.1262/jrd.2014-009. Epub 2014 Sep 29.


Successful immunotherapy of autoimmune cholangitis by adoptive transfer of forkhead box protein 3(+) regulatory T cells.

Tanaka H, Zhang W, Yang GX, Ando Y, Tomiyama T, Tsuneyama K, Leung P, Coppel RL, Ansari AA, Lian ZX, Ridgway WM, Joh T, Gershwin ME.

Clin Exp Immunol. 2014 Nov;178(2):253-61. doi: 10.1111/cei.12415.


Neurofibrillary tangle formation by introducing wild-type human tau into APP transgenic mice.

Umeda T, Maekawa S, Kimura T, Takashima A, Tomiyama T, Mori H.

Acta Neuropathol. 2014 May;127(5):685-98. doi: 10.1007/s00401-014-1259-1. Epub 2014 Feb 15.


Diagnosis and classification of autoimmune pancreatitis.

Okazaki K, Tomiyama T, Mitsuyama T, Sumimoto K, Uchida K.

Autoimmun Rev. 2014 Apr-May;13(4-5):451-8. doi: 10.1016/j.autrev.2014.01.010. Epub 2014 Jan 12. Review.


The E693Δ (Osaka) mutation in amyloid precursor protein potentiates cholesterol-mediated intracellular amyloid β toxicity via its impaired cholesterol efflux.

Nomura S, Umeda T, Tomiyama T, Mori H.

J Neurosci Res. 2013 Dec;91(12):1541-50. doi: 10.1002/jnr.23278. Epub 2013 Sep 16.


Antigen-specific suppression and immunological synapse formation by regulatory T cells require the Mst1 kinase.

Tomiyama T, Ueda Y, Katakai T, Kondo N, Okazaki K, Kinashi T.

PLoS One. 2013 Sep 9;8(9):e73874. doi: 10.1371/journal.pone.0073874. eCollection 2013.


Evaluation of oxygen consumption in human vitrified and warmed pre-antral follicles after prolonged low temperatures.

Kyoya T, Nakamura Y, Miyatani S, Miyagawa T, Tomiyama T, Kyono K.

Reprod Med Biol. 2013 Aug 8;13(1):47-52. doi: 10.1007/s12522-013-0166-9. eCollection 2014 Jan.


A proposal of a diagnostic algorithm with validation of International Consensus Diagnostic Criteria for autoimmune pancreatitis in a Japanese cohort.

Sumimoto K, Uchida K, Mitsuyama T, Fukui Y, Kusuda T, Miyoshi H, Tomiyama T, Fukata N, Koyabu M, Sakaguchi Y, Ikeura T, Shimatani M, Fukui T, Matsushita M, Takaoka M, Nishio A, Okazaki K.

Pancreatology. 2013 May-Jun;13(3):230-7. doi: 10.1016/j.pan.2013.02.010. Epub 2013 Mar 14.


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