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Items: 47

1.

Loss of Blood-Brain Barrier Integrity in a KCl-Induced Model of Episodic Headache Enhances CNS Drug Delivery.

Cottier KE, Galloway EA, Calabrese EC, Tome ME, Liktor-Busa E, Kim J, Davis TP, Vanderah TW, Largent-Milnes TM.

eNeuro. 2018 Jul 16;5(4). pii: ENEURO.0116-18.2018. doi: 10.1523/ENEURO.0116-18.2018. eCollection 2018 Jul-Aug.

2.

Chronic morphine exposure potentiates p-glycoprotein trafficking from nuclear reservoirs in cortical rat brain microvessels.

Schaefer CP, Arkwright NB, Jacobs LM, Jarvis CK, Hunn KC, Largent-Milnes TM, Tome ME, Davis TP.

PLoS One. 2018 Feb 7;13(2):e0192340. doi: 10.1371/journal.pone.0192340. eCollection 2018.

3.

Radiation-Mediated Tumor Growth Inhibition Is Significantly Enhanced with Redox-Active Compounds That Cycle with Ascorbate.

Tovmasyan A, Bueno-Janice JC, Jaramillo MC, Sampaio RS, Reboucas JS, Kyui N, Benov L, Deng B, Huang TT, Tome ME, Spasojevic I, Batinic-Haberle I.

Antioxid Redox Signal. 2018 Nov 1;29(13):1196-1214. doi: 10.1089/ars.2017.7218. Epub 2018 Mar 27.

PMID:
29390861
4.

The opioid epidemic: a central role for the blood brain barrier in opioid analgesia and abuse.

Schaefer CP, Tome ME, Davis TP.

Fluids Barriers CNS. 2017 Nov 29;14(1):32. doi: 10.1186/s12987-017-0080-3. Review.

5.

P-glycoprotein traffics from the nucleus to the plasma membrane in rat brain endothelium during inflammatory pain.

Tome ME, Herndon JM, Schaefer CP, Jacobs LM, Zhang Y, Jarvis CK, Davis TP.

J Cereb Blood Flow Metab. 2016 Nov;36(11):1913-1928. Epub 2016 Jul 27.

6.

Identification of P-glycoprotein co-fractionating proteins and specific binding partners in rat brain microvessels.

Tome ME, Schaefer CP, Jacobs LM, Zhang Y, Herndon JM, Matty FO, Davis TP.

J Neurochem. 2015 Jul;134(2):200-10. doi: 10.1111/jnc.13106. Epub 2015 Apr 21.

7.

Manganese (III) meso-tetrakis N-ethylpyridinium-2-yl porphyrin acts as a pro-oxidant to inhibit electron transport chain proteins, modulate bioenergetics, and enhance the response to chemotherapy in lymphoma cells.

Jaramillo MC, Briehl MM, Batinic-Haberle I, Tome ME.

Free Radic Biol Med. 2015 Jun;83:89-100. doi: 10.1016/j.freeradbiomed.2015.01.031. Epub 2015 Feb 26.

8.

P-glycoprotein trafficking as a therapeutic target to optimize CNS drug delivery.

Davis TP, Sanchez-Covarubias L, Tome ME.

Adv Pharmacol. 2014;71:25-44. doi: 10.1016/bs.apha.2014.06.009. Epub 2014 Aug 23. Review.

9.

Mitochondria and redox homoeostasis as chemotherapeutic targets.

Briehl MM, Tome ME, Wilkinson ST, Jaramillo MC, Lee K.

Biochem Soc Trans. 2014 Aug;42(4):939-44. doi: 10.1042/BST20140087. Review.

10.

The copper chelator ATN-224 induces caspase-independent cell death in diffuse large B cell lymphoma.

Lee K, Hart MR, Briehl MM, Mazar AP, Tome ME.

Int J Oncol. 2014 Jul;45(1):439-47. doi: 10.3892/ijo.2014.2396. Epub 2014 Apr 23.

11.

The copper chelator ATN-224 induces peroxynitrite-dependent cell death in hematological malignancies.

Lee K, Briehl MM, Mazar AP, Batinic-Haberle I, Reboucas JS, Glinsmann-Gibson B, Rimsza LM, Tome ME.

Free Radic Biol Med. 2013 Jul;60:157-67. doi: 10.1016/j.freeradbiomed.2013.02.003. Epub 2013 Feb 14.

12.

Mitochondrial adaptations to oxidative stress confer resistance to apoptosis in lymphoma cells.

Wilkinson ST, Tome ME, Briehl MM.

Int J Mol Sci. 2012;13(8):10212-28. doi: 10.3390/ijms130810212. Epub 2012 Aug 16.

13.
14.

Lymphoma cells with increased anti-oxidant defenses acquire chemoresistance.

Tome ME, Frye JB, Coyle DL, Jacobson EL, Samulitis BK, Dvorak K, Dorr RT, Briehl MM.

Exp Ther Med. 2012 May;3(5):845-852. Epub 2012 Feb 14.

15.

Manganese porphyrin, MnTE-2-PyP5+, Acts as a pro-oxidant to potentiate glucocorticoid-induced apoptosis in lymphoma cells.

Jaramillo MC, Briehl MM, Crapo JD, Batinic-Haberle I, Tome ME.

Free Radic Biol Med. 2012 Apr 15;52(8):1272-84. doi: 10.1016/j.freeradbiomed.2012.02.001. Epub 2012 Feb 11.

16.

Hydrogen peroxide signaling is required for glucocorticoid-induced apoptosis in lymphoma cells.

Tome ME, Jaramillo MC, Briehl MM.

Free Radic Biol Med. 2011 Dec 1;51(11):2048-59. doi: 10.1016/j.freeradbiomed.2011.09.002. Epub 2011 Sep 10.

17.

A strategy for full interrogation of prognostic gene expression patterns: exploring the biology of diffuse large B cell lymphoma.

Rimsza LM, Unger JM, Tome ME, Leblanc ML.

PLoS One. 2011;6(8):e22267. doi: 10.1371/journal.pone.0022267. Epub 2011 Aug 4.

18.

Characterization of squamous esophageal cells resistant to bile acids at acidic pH: implication for Barrett's esophagus pathogenesis.

Goldman A, Chen HD, Roesly HB, Hill KA, Tome ME, Dvorak B, Bernstein H, Dvorak K.

Am J Physiol Gastrointest Liver Physiol. 2011 Feb;300(2):G292-302. doi: 10.1152/ajpgi.00461.2010. Epub 2010 Dec 2.

19.

Increased cytochrome c correlates with poor survival in aggressive lymphoma.

Wilkinson ST, Johnson DB, Tardif HL, Tome ME, Briehl MM.

Oncol Lett. 2010 Mar;1(2):227-230.

20.

Increased manganese superoxide dismutase expression or treatment with manganese porphyrin potentiates dexamethasone-induced apoptosis in lymphoma cells.

Jaramillo MC, Frye JB, Crapo JD, Briehl MM, Tome ME.

Cancer Res. 2009 Jul 1;69(13):5450-7. doi: 10.1158/0008-5472.CAN-08-4031. Epub 2009 Jun 23.

21.

Modulation of human glutathione s-transferases by polyphenon e intervention.

Chow HH, Hakim IA, Vining DR, Crowell JA, Tome ME, Ranger-Moore J, Cordova CA, Mikhael DM, Briehl MM, Alberts DS.

Cancer Epidemiol Biomarkers Prev. 2007 Aug;16(8):1662-6.

22.

Glucose 6-phosphate dehydrogenase overexpression models glucose deprivation and sensitizes lymphoma cells to apoptosis.

Tome ME, Johnson DB, Samulitis BK, Dorr RT, Briehl MM.

Antioxid Redox Signal. 2006 Jul-Aug;8(7-8):1315-27.

PMID:
16910779
23.

Catalase reverses tumorigenicity in a malignant cell line by an epidermal growth factor receptor pathway.

Finch JS, Tome ME, Kwei KA, Bowden GT.

Free Radic Biol Med. 2006 Mar 1;40(5):863-75. Epub 2005 Nov 2.

PMID:
16520238
24.

A redox signature score identifies diffuse large B-cell lymphoma patients with a poor prognosis.

Tome ME, Johnson DB, Rimsza LM, Roberts RA, Grogan TM, Miller TP, Oberley LW, Briehl MM.

Blood. 2005 Nov 15;106(10):3594-601. Epub 2005 Aug 4.

25.

Molecular modes of action of cantharidin in tumor cells.

Efferth T, Rauh R, Kahl S, Tomicic M, Böchzelt H, Tome ME, Briehl MM, Bauer R, Kaina B.

Biochem Pharmacol. 2005 Mar 1;69(5):811-8. Epub 2005 Jan 21.

PMID:
15710358
26.

Increasing the antioxidant defense in WEHI7.2 cells results in a more tumor-like metabolic profile.

Tome ME, Briehl MM, Lutz NW.

Int J Mol Med. 2005 Mar;15(3):497-501.

PMID:
15702245
27.
29.

Role of antioxidant genes for the activity of artesunate against tumor cells.

Efferth T, Briehl MM, Tome ME.

Int J Oncol. 2003 Oct;23(4):1231-5.

PMID:
12964009
30.

Early changes in glucose and phospholipid metabolism following apoptosis induction by IFN-gamma/TNF-alpha in HT-29 cells.

Lutz NW, Tome ME, Cozzone PJ.

FEBS Lett. 2003 Jun 5;544(1-3):123-8. Erratum in: FEBS Lett. 2003 Sep 25;552(2-3):264.

31.

Molecular and cellular characterization of imexon-resistant RPMI8226/I myeloma cells.

Dvorakova K, Payne CM, Tome ME, Briehl MM, Vasquez MA, Waltmire CN, Coon A, Dorr RT.

Mol Cancer Ther. 2002 Jan;1(3):185-95.

32.

Imexon activates an intrinsic apoptosis pathway in RPMI8226 myeloma cells.

Dvorakova K, Payne CM, Landowski TH, Tome ME, Halperin DS, Dorr RT.

Anticancer Drugs. 2002 Nov;13(10):1031-42.

PMID:
12439337
35.

Induction of mitochondrial changes in myeloma cells by imexon.

Dvorakova K, Waltmire CN, Payne CM, Tome ME, Briehl MM, Dorr RT.

Blood. 2001 Jun 1;97(11):3544-51.

36.

Catalase-overexpressing thymocytes are resistant to glucocorticoid-induced apoptosis and exhibit increased net tumor growth.

Tome ME, Baker AF, Powis G, Payne CM, Briehl MM.

Cancer Res. 2001 Mar 15;61(6):2766-73.

37.

Induction of oxidative stress and apoptosis in myeloma cells by the aziridine-containing agent imexon.

Dvorakova K, Payne CM, Tome ME, Briehl MM, McClure T, Dorr RT.

Biochem Pharmacol. 2000 Sep 15;60(6):749-58.

PMID:
10930529
38.
39.
40.

Loss of intracellular putrescine pool-size regulation induces apoptosis.

Xie X, Tome ME, Gerner EW.

Exp Cell Res. 1997 Feb 1;230(2):386-92.

PMID:
9024798
42.

Consequences of aberrant ornithine decarboxylase regulation in rat hepatoma cells.

Tome ME, Fiser SM, Gerner EW.

J Cell Physiol. 1994 Feb;158(2):237-44.

PMID:
8106560
43.

Polyamine catabolism in rodent and human cells in culture.

Carper SW, Tome ME, Fuller DJ, Chen JR, Harari PM, Gerner EW.

Biochem J. 1991 Dec 1;280 ( Pt 2):289-94.

44.
45.

Inhibition of ionizing radiation recovery processes in polyamine-depleted Chinese hamster cells.

Gerner EW, Tome ME, Fry SE, Bowden GT.

Cancer Res. 1988 Sep 1;48(17):4881-5.

46.

Hypusine biosynthesis in protein and its biological consequences.

Murphey RJ, Tome ME, Gerner EW.

Adv Exp Med Biol. 1988;250:449-58. Review. No abstract available.

PMID:
3151230
47.

Adrenal responses to chronic and acute water stress in Japanese quail Coturnix japonica.

Tome ME, McNabb FM, Gwazdauskas FC.

Comp Biochem Physiol A Comp Physiol. 1985;81(1):171-9.

PMID:
2859951

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