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Items: 15

1.

Regional differences in human biliary tissues and corresponding in vitro derived organoids.

Rimland CA, Tilson SG, Morell CM, Tomaz RA, Lu WY, Adams SE, Georgakopoulos N, Otaizo-Carrasquero F, Myers TG, Ferdinand JR, Gieseck RL 3rd, Sampaziotis F, Tysoe OC, Wesley B, Muraro D, Oniscu GC, Hannan NR, Forbes SJ, Saeb-Parsy K, Wynn TA, Vallier L.

Hepatology. 2020 Mar 29. doi: 10.1002/hep.31252. [Epub ahead of print]

PMID:
32222998
2.

Dynamic CpG methylation delineates subregions within super-enhancers selectively decommissioned at the exit from naive pluripotency.

Bell E, Curry EW, Megchelenbrink W, Jouneau L, Brochard V, Tomaz RA, Mau KHT, Atlasi Y, de Souza RA, Marks H, Stunnenberg HG, Jouneau A, Azuara V.

Nat Commun. 2020 Feb 28;11(1):1112. doi: 10.1038/s41467-020-14916-7.

3.

Publisher Correction: GDF15 mediates the effects of metformin on body weight and energy balance.

Coll AP, Chen M, Taskar P, Rimmington D, Patel S, Tadross JA, Cimino I, Yang M, Welsh P, Virtue S, Goldspink DA, Miedzybrodzka EL, Konopka AR, Esponda RR, Huang JT, Tung YCL, Rodriguez-Cuenca S, Tomaz RA, Harding HP, Melvin A, Yeo GSH, Preiss D, Vidal-Puig A, Vallier L, Nair KS, Wareham NJ, Ron D, Gribble FM, Reimann F, Sattar N, Savage DB, Allan BB, O'Rahilly S.

Nature. 2020 Feb;578(7796):E24. doi: 10.1038/s41586-020-2031-4.

PMID:
32051582
4.

GDF15 mediates the effects of metformin on body weight and energy balance.

Coll AP, Chen M, Taskar P, Rimmington D, Patel S, Tadross JA, Cimino I, Yang M, Welsh P, Virtue S, Goldspink DA, Miedzybrodzka EL, Konopka AR, Esponda RR, Huang JT, Tung YCL, Rodriguez-Cuenca S, Tomaz RA, Harding HP, Melvin A, Yeo GSH, Preiss D, Vidal-Puig A, Vallier L, Nair KS, Wareham NJ, Ron D, Gribble FM, Reimann F, Sattar N, Savage DB, Allan BB, O'Rahilly S.

Nature. 2020 Feb;578(7795):444-448. doi: 10.1038/s41586-019-1911-y. Epub 2019 Dec 25. Erratum in: Nature. 2020 Feb 13;:.

PMID:
31875646
5.

Method to Synchronize Cell Cycle of Human Pluripotent Stem Cells without Affecting Their Fundamental Characteristics.

Yiangou L, Grandy RA, Morell CM, Tomaz RA, Osnato A, Kadiwala J, Muraro D, Garcia-Bernardo J, Nakanoh S, Bernard WG, Ortmann D, McCarthy DJ, Simonic I, Sinha S, Vallier L.

Stem Cell Reports. 2019 Jan 8;12(1):165-179. doi: 10.1016/j.stemcr.2018.11.020. Epub 2018 Dec 27.

6.

Modeling Disease with Human Inducible Pluripotent Stem Cells.

Grandy R, Tomaz RA, Vallier L.

Annu Rev Pathol. 2019 Jan 24;14:449-468. doi: 10.1146/annurev-pathol-020117-043634. Epub 2018 Oct 24.

PMID:
30355153
7.

3D human liver tissue from pluripotent stem cells displays stable phenotype in vitro and supports compromised liver function in vivo.

Rashidi H, Luu NT, Alwahsh SM, Ginai M, Alhaque S, Dong H, Tomaz RA, Vernay B, Vigneswara V, Hallett JM, Chandrashekran A, Dhawan A, Vallier L, Bradley M, Callanan A, Forbes SJ, Newsome PN, Hay DC.

Arch Toxicol. 2018 Oct;92(10):3117-3129. doi: 10.1007/s00204-018-2280-2. Epub 2018 Aug 28.

8.

Jmjd2c facilitates the assembly of essential enhancer-protein complexes at the onset of embryonic stem cell differentiation.

Tomaz RA, Harman JL, Karimlou D, Weavers L, Fritsch L, Bou-Kheir T, Bell E, Del Valle Torres I, Niakan KK, Fisher C, Joshi O, Stunnenberg HG, Curry E, Ait-Si-Ali S, Jørgensen HF, Azuara V.

Development. 2017 Feb 15;144(4):567-579. doi: 10.1242/dev.142489. Epub 2017 Jan 13.

9.

Identification of a novel germline FOXE1 variant in patients with familial non-medullary thyroid carcinoma (FNMTC).

Pereira JS, da Silva JG, Tomaz RA, Pinto AE, Bugalho MJ, Leite V, Cavaco BM.

Endocrine. 2015 May;49(1):204-14. doi: 10.1007/s12020-014-0470-0. Epub 2014 Nov 9.

PMID:
25381600
10.

Ncoa3 functions as an essential Esrrb coactivator to sustain embryonic stem cell self-renewal and reprogramming.

Percharde M, Lavial F, Ng JH, Kumar V, Tomaz RA, Martin N, Yeo JC, Gil J, Prabhakar S, Ng HH, Parker MG, Azuara V.

Genes Dev. 2012 Oct 15;26(20):2286-98. doi: 10.1101/gad.195545.112. Epub 2012 Sep 26.

11.

FOXE1 polymorphisms are associated with familial and sporadic nonmedullary thyroid cancer susceptibility.

Tomaz RA, Sousa I, Silva JG, Santos C, Teixeira MR, Leite V, Cavaco BM.

Clin Endocrinol (Oxf). 2012 Dec;77(6):926-33. doi: 10.1111/j.1365-2265.2012.04505.x.

PMID:
22882326
12.

Bmi1 facilitates primitive endoderm formation by stabilizing Gata6 during early mouse development.

Lavial F, Bessonnard S, Ohnishi Y, Tsumura A, Chandrashekran A, Fenwick MA, Tomaz RA, Hosokawa H, Nakayama T, Chambers I, Hiiragi T, Chazaud C, Azuara V.

Genes Dev. 2012 Jul 1;26(13):1445-58. doi: 10.1101/gad.188193.112. Epub 2012 Jun 19.

13.

Identification of the first germline HRPT2 whole-gene deletion in a patient with primary hyperparathyroidism.

Domingues R, Tomaz RA, Martins C, Nunes C, Bugalho MJ, Cavaco BM.

Clin Endocrinol (Oxf). 2012 Jan;76(1):33-8. doi: 10.1111/j.1365-2265.2011.04184.x.

PMID:
21790700
14.

Clinical and genetic characterization of Portuguese patients with pseudohypoparathyroidism type Ib.

Cavaco BM, Tomaz RA, Fonseca F, Mascarenhas MR, Leite V, Sobrinho LG.

Endocrine. 2010 Jun;37(3):408-14. doi: 10.1007/s12020-010-9321-9. Epub 2010 Mar 30.

PMID:
20960161
15.

Differential methylation as a cause of allele dropout at the imprinted GNAS locus.

Tomaz RA, Cavaco BM, Leite V.

Genet Test Mol Biomarkers. 2010 Aug;14(4):455-60. doi: 10.1089/gtmb.2010.0029.

PMID:
20642365

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