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Items: 1 to 50 of 70

1.

Sirt3 Deficiency Shortens Life Span and Impairs Cardiac Mitochondrial Function Rescued by Opa1 Gene Transfer.

Benigni A, Cassis P, Conti S, Perico L, Corna D, Cerullo D, Zentilin L, Zoja C, Perna A, Lionetti V, Giacca M, Trionfini P, Tomasoni S, Remuzzi G.

Antioxid Redox Signal. 2019 Aug 2. doi: 10.1089/ars.2018.7703. [Epub ahead of print]

PMID:
31269804
2.

Engineering the vasculature of decellularized rat kidney scaffolds using human induced pluripotent stem cell-derived endothelial cells.

Ciampi O, Bonandrini B, Derosas M, Conti S, Rizzo P, Benedetti V, Figliuzzi M, Remuzzi A, Benigni A, Remuzzi G, Tomasoni S.

Sci Rep. 2019 May 29;9(1):8001. doi: 10.1038/s41598-019-44393-y.

3.

CRISPR-Cas9-Mediated Correction of the G189R-PAX2 Mutation in Induced Pluripotent Stem Cells from a Patient with Focal Segmental Glomerulosclerosis.

Trionfini P, Ciampi O, Todeschini M, Ascanelli C, Longaretti L, Perico L, Remuzzi G, Benigni A, Tomasoni S.

CRISPR J. 2019 Apr;2:108-120. doi: 10.1089/crispr.2018.0048.

PMID:
30998089
4.
5.

Engineered Kidney Tubules for Modeling Patient-Specific Diseases and Drug Discovery.

Benedetti V, Brizi V, Guida P, Tomasoni S, Ciampi O, Angeli E, Valbusa U, Benigni A, Remuzzi G, Xinaris C.

EBioMedicine. 2018 Jul;33:253-268. doi: 10.1016/j.ebiom.2018.06.005. Epub 2018 Jul 3.

6.

Extracellular vesicles derived from T regulatory cells suppress T cell proliferation and prolong allograft survival.

Aiello S, Rocchetta F, Longaretti L, Faravelli S, Todeschini M, Cassis L, Pezzuto F, Tomasoni S, Azzollini N, Mister M, Mele C, Conti S, Breno M, Remuzzi G, Noris M, Benigni A.

Sci Rep. 2017 Sep 14;7(1):11518. doi: 10.1038/s41598-017-08617-3.

7.

MicroRNA-184 is a downstream effector of albuminuria driving renal fibrosis in rats with diabetic nephropathy.

Zanchi C, Macconi D, Trionfini P, Tomasoni S, Rottoli D, Locatelli M, Rudnicki M, Vandesompele J, Mestdagh P, Remuzzi G, Benigni A, Zoja C.

Diabetologia. 2017 Jun;60(6):1114-1125. doi: 10.1007/s00125-017-4248-9. Epub 2017 Mar 31.

8.

AAV9-mediated engineering of autotransplanted kidney of non-human primates.

Tomasoni S, Trionfini P, Azzollini N, Zentilin L, Giacca M, Aiello S, Longaretti L, Cozzi E, Baldan N, Remuzzi G, Benigni A.

Gene Ther. 2017 May;24(5):308-313. doi: 10.1038/gt.2017.21. Epub 2017 Mar 27.

PMID:
28346435
9.

Generation of functional podocytes from human induced pluripotent stem cells.

Ciampi O, Iacone R, Longaretti L, Benedetti V, Graf M, Magnone MC, Patsch C, Xinaris C, Remuzzi G, Benigni A, Tomasoni S.

Stem Cell Res. 2016 Jul;17(1):130-9. doi: 10.1016/j.scr.2016.06.001. Epub 2016 Jun 3.

10.

Functional Human Podocytes Generated in Organoids from Amniotic Fluid Stem Cells.

Xinaris C, Benedetti V, Novelli R, Abbate M, Rizzo P, Conti S, Tomasoni S, Corna D, Pozzobon M, Cavallotti D, Yokoo T, Morigi M, Benigni A, Remuzzi G.

J Am Soc Nephrol. 2016 May;27(5):1400-11. doi: 10.1681/ASN.2015030316. Epub 2015 Oct 29.

11.

Regression of Renal Disease by Angiotensin II Antagonism Is Caused by Regeneration of Kidney Vasculature.

Remuzzi A, Sangalli F, Macconi D, Tomasoni S, Cattaneo I, Rizzo P, Bonandrini B, Bresciani E, Longaretti L, Gagliardini E, Conti S, Benigni A, Remuzzi G.

J Am Soc Nephrol. 2016 Mar;27(3):699-705. doi: 10.1681/ASN.2014100971. Epub 2015 Jun 26.

12.

Direct reprogramming of human bone marrow stromal cells into functional renal cells using cell-free extracts.

Papadimou E, Morigi M, Iatropoulos P, Xinaris C, Tomasoni S, Benedetti V, Longaretti L, Rota C, Todeschini M, Rizzo P, Introna M, Grazia de Simoni M, Remuzzi G, Goligorsky MS, Benigni A.

Stem Cell Reports. 2015 Apr 14;4(4):685-98. doi: 10.1016/j.stemcr.2015.02.002. Epub 2015 Mar 5.

13.

Renal progenitors derived from human iPSCs engraft and restore function in a mouse model of acute kidney injury.

Imberti B, Tomasoni S, Ciampi O, Pezzotta A, Derosas M, Xinaris C, Rizzo P, Papadimou E, Novelli R, Benigni A, Remuzzi G, Morigi M.

Sci Rep. 2015 Mar 6;5:8826. doi: 10.1038/srep08826.

14.

Shiga toxin promotes podocyte injury in experimental hemolytic uremic syndrome via activation of the alternative pathway of complement.

Locatelli M, Buelli S, Pezzotta A, Corna D, Perico L, Tomasoni S, Rottoli D, Rizzo P, Conti D, Thurman JM, Remuzzi G, Zoja C, Morigi M.

J Am Soc Nephrol. 2014 Aug;25(8):1786-98. doi: 10.1681/ASN.2013050450. Epub 2014 Feb 27.

15.

Renal expression of FGF23 in progressive renal disease of diabetes and the effect of ACE inhibitor.

Zanchi C, Locatelli M, Benigni A, Corna D, Tomasoni S, Rottoli D, Gaspari F, Remuzzi G, Zoja C.

PLoS One. 2013 Aug 14;8(8):e70775. doi: 10.1371/journal.pone.0070775. eCollection 2013.

16.

Post-transcriptional gene regulation makes things clearer in renal fibrosis.

Tomasoni S, Benigni A.

J Am Soc Nephrol. 2013 Jun;24(7):1026-8. doi: 10.1681/ASN.2013040411. Epub 2013 May 30. No abstract available.

17.

Angiotensin II contributes to diabetic renal dysfunction in rodents and humans via Notch1/Snail pathway.

Gagliardini E, Perico N, Rizzo P, Buelli S, Longaretti L, Perico L, Tomasoni S, Zoja C, Macconi D, Morigi M, Remuzzi G, Benigni A.

Am J Pathol. 2013 Jul;183(1):119-30. doi: 10.1016/j.ajpath.2013.03.025. Epub 2013 May 23.

18.

Transfer of growth factor receptor mRNA via exosomes unravels the regenerative effect of mesenchymal stem cells.

Tomasoni S, Longaretti L, Rota C, Morigi M, Conti S, Gotti E, Capelli C, Introna M, Remuzzi G, Benigni A.

Stem Cells Dev. 2013 Mar 1;22(5):772-80. doi: 10.1089/scd.2012.0266. Epub 2012 Dec 21.

19.

MicroRNA-324-3p promotes renal fibrosis and is a target of ACE inhibition.

Macconi D, Tomasoni S, Romagnani P, Trionfini P, Sangalli F, Mazzinghi B, Rizzo P, Lazzeri E, Abbate M, Remuzzi G, Benigni A.

J Am Soc Nephrol. 2012 Sep;23(9):1496-505. doi: 10.1681/ASN.2011121144. Epub 2012 Jul 19.

20.

MYO1E mutations and childhood familial focal segmental glomerulosclerosis.

Mele C, Iatropoulos P, Donadelli R, Calabria A, Maranta R, Cassis P, Buelli S, Tomasoni S, Piras R, Krendel M, Bettoni S, Morigi M, Delledonne M, Pecoraro C, Abbate I, Capobianchi MR, Hildebrandt F, Otto E, Schaefer F, Macciardi F, Ozaltin F, Emre S, Ibsirlioglu T, Benigni A, Remuzzi G, Noris M; PodoNet Consortium.

N Engl J Med. 2011 Jul 28;365(4):295-306. doi: 10.1056/NEJMoa1101273. Epub 2011 Jul 14.

21.

The Toll-IL-1R member Tir8/SIGIRR negatively regulates adaptive immunity against kidney grafts.

Noris M, Cassis P, Azzollini N, Cavinato R, Cugini D, Casiraghi F, Aiello S, Solini S, Cassis L, Mister M, Todeschini M, Abbate M, Benigni A, Trionfini P, Tomasoni S, Mele C, Garlanda C, Polentarutti N, Mantovani A, Remuzzi G.

J Immunol. 2009 Oct 1;183(7):4249-60. doi: 10.4049/jimmunol.0803549. Epub 2009 Sep 4.

22.

Adenoviral-mediated gene transfer restores plasma ADAMTS13 antigen and activity in ADAMTS13 knockout mice.

Trionfini P, Tomasoni S, Galbusera M, Motto D, Longaretti L, Corna D, Remuzzi G, Benigni A.

Gene Ther. 2009 Nov;16(11):1373-9. doi: 10.1038/gt.2009.98. Epub 2009 Aug 13.

PMID:
19675594
23.

Allograft rejection: acute and chronic studies.

Tomasoni S, Remuzzi G, Benigni A.

Contrib Nephrol. 2008;159:122-134. doi: 10.1159/000125672. Review.

PMID:
18391589
24.

Complement-mediated dysfunction of glomerular filtration barrier accelerates progressive renal injury.

Abbate M, Zoja C, Corna D, Rottoli D, Zanchi C, Azzollini N, Tomasoni S, Berlingeri S, Noris M, Morigi M, Remuzzi G.

J Am Soc Nephrol. 2008 Jun;19(6):1158-67. doi: 10.1681/ASN.2007060686. Epub 2008 Mar 19.

25.

Insulin-like growth factor-1 sustains stem cell mediated renal repair.

Imberti B, Morigi M, Tomasoni S, Rota C, Corna D, Longaretti L, Rottoli D, Valsecchi F, Benigni A, Wang J, Abbate M, Zoja C, Remuzzi G.

J Am Soc Nephrol. 2007 Nov;18(11):2921-8. Epub 2007 Oct 17.

26.

DnIKK2-transfected dendritic cells induce a novel population of inducible nitric oxide synthase-expressing CD4+CD25- cells with tolerogenic properties.

Aiello S, Cassis P, Cassis L, Tomasoni S, Benigni A, Pezzotta A, Cavinato RA, Cugini D, Azzollini N, Mister M, Longaretti L, Thomson AW, Remuzzi G, Noris M.

Transplantation. 2007 Feb 27;83(4):474-84.

PMID:
17318081
27.

Transcriptional regulation of nephrin gene by peroxisome proliferator-activated receptor-gamma agonist: molecular mechanism of the antiproteinuric effect of pioglitazone.

Benigni A, Zoja C, Tomasoni S, Campana M, Corna D, Zanchi C, Gagliardini E, Garofano E, Rottoli D, Ito T, Remuzzi G.

J Am Soc Nephrol. 2006 Jun;17(6):1624-32. Epub 2006 May 10.

28.

Adeno-associated virus-mediated CTLA4Ig gene transfer protects MHC-mismatched renal allografts from chronic rejection.

Benigni A, Tomasoni S, Turka LA, Longaretti L, Zentilin L, Mister M, Pezzotta A, Azzollini N, Noris M, Conti S, Abbate M, Giacca M, Remuzzi G.

J Am Soc Nephrol. 2006 Jun;17(6):1665-72. Epub 2006 Apr 26.

29.

Dendritic cells genetically engineered with adenoviral vector encoding dnIKK2 induce the formation of potent CD4+ T-regulatory cells.

Tomasoni S, Aiello S, Cassis L, Noris M, Longaretti L, Cavinato RA, Azzollini N, Pezzotta A, Remuzzi G, Benigni A.

Transplantation. 2005 May 15;79(9):1056-61.

PMID:
15880043
30.

The goal of intragraft gene therapy.

Tomasoni S, Benigni A.

Contrib Nephrol. 2005;146:143-150. doi: 10.1159/000082074. Review.

PMID:
15567928
31.

Mesenchymal stem cells are renotropic, helping to repair the kidney and improve function in acute renal failure.

Morigi M, Imberti B, Zoja C, Corna D, Tomasoni S, Abbate M, Rottoli D, Angioletti S, Benigni A, Perico N, Alison M, Remuzzi G.

J Am Soc Nephrol. 2004 Jul;15(7):1794-804.

32.

Selective impairment of gene expression and assembly of nephrin in human diabetic nephropathy.

Benigni A, Gagliardini E, Tomasoni S, Abbate M, Ruggenenti P, Kalluri R, Remuzzi G.

Kidney Int. 2004 Jun;65(6):2193-200.

33.

Favorable effect of cotransfection with TGF-beta and CTLA4Ig of the donor kidney on allograft survival.

Tomasoni S, Longaretti L, Azzollini N, Gagliardini E, Mister M, Buehler T, Remuzzi G, Benigni A.

Am J Nephrol. 2004 May-Jun;24(3):275-83. Epub 2004 Mar 30.

PMID:
15057025
34.

Gene therapy: how to target the kidney. Promises and pitfalls.

Tomasoni S, Benigni A.

Curr Gene Ther. 2004 Mar;4(1):115-22. Review.

PMID:
15032618
35.

Unique pattern of expression and inhibition of IL-1 signaling by the IL-1 receptor family member TIR8/SIGIRR.

Polentarutti N, Rol GP, Muzio M, Bosisio D, Camnasio M, Riva F, Zoja C, Benigni A, Tomasoni S, Vecchi A, Garlanda C, Mantovani A.

Eur Cytokine Netw. 2003 Oct-Dec;14(4):211-8.

36.

Protein overload induces fractalkine upregulation in proximal tubular cells through nuclear factor kappaB- and p38 mitogen-activated protein kinase-dependent pathways.

Donadelli R, Zanchi C, Morigi M, Buelli S, Batani C, Tomasoni S, Corna D, Rottoli D, Benigni A, Abbate M, Remuzzi G, Zoja C.

J Am Soc Nephrol. 2003 Oct;14(10):2436-46.

37.

Targeted downregulation of extracellular nephrin in human IgA nephropathy.

Gagliardini E, Benigni A, Tomasoni S, Abbate M, Kalluri R, Remuzzi G.

Am J Nephrol. 2003 Jul-Aug;23(4):277-86. Epub 2003 Jul 9.

38.

Transforming growth factor-beta1 is up-regulated by podocytes in response to excess intraglomerular passage of proteins: a central pathway in progressive glomerulosclerosis.

Abbate M, Zoja C, Morigi M, Rottoli D, Angioletti S, Tomasoni S, Zanchi C, Longaretti L, Donadelli R, Remuzzi G.

Am J Pathol. 2002 Dec;161(6):2179-93.

39.

Shiga toxin-2 triggers endothelial leukocyte adhesion and transmigration via NF-kappaB dependent up-regulation of IL-8 and MCP-1.

Zoja C, Angioletti S, Donadelli R, Zanchi C, Tomasoni S, Binda E, Imberti B, te Loo M, Monnens L, Remuzzi G, Morigi M.

Kidney Int. 2002 Sep;62(3):846-56.

40.

Proximal tubular cells promote fibrogenesis by TGF-beta1-mediated induction of peritubular myofibroblasts.

Abbate M, Zoja C, Rottoli D, Corna D, Tomasoni S, Remuzzi G.

Kidney Int. 2002 Jun;61(6):2066-77. Erratum in: Kidney Int 2002 Aug;62(2):731.

41.

Effect of combining ACE inhibitor and statin in severe experimental nephropathy.

Zoja C, Corna D, Rottoli D, Cattaneo D, Zanchi C, Tomasoni S, Abbate M, Remuzzi G.

Kidney Int. 2002 May;61(5):1635-45.

42.
43.

Gene therapy to the kidney.

Tomasoni S, Remuzzi G, Benigni A.

Contrib Nephrol. 2001;(136):140-56. Review. No abstract available.

PMID:
11688377
44.

Blocking angiotensin II synthesis/activity preserves glomerular nephrin in rats with severe nephrosis.

Benigni A, Tomasoni S, Gagliardini E, Zoja C, Grunkemeyer JA, Kalluri R, Remuzzi G.

J Am Soc Nephrol. 2001 May;12(5):941-8.

45.

Protein traffic activates NF-kB gene signaling and promotes MCP-1-dependent interstitial inflammation.

Donadelli R, Abbate M, Zanchi C, Corna D, Tomasoni S, Benigni A, Remuzzi G, Zoja C.

Am J Kidney Dis. 2000 Dec;36(6):1226-41.

PMID:
11096048
46.

Nonviral and viral gene transfer to the kidney in the context of transplantation.

Benigni A, Tomasoni S, Lutz J, Amuchastegui S, Capogrossi MC, Remuzzi G.

Nephron. 2000 Aug;85(4):307-16.

PMID:
10940741
47.

Thymic dendritic cells express inducible nitric oxide synthase and generate nitric oxide in response to self- and alloantigens.

Aiello S, Noris M, Piccinini G, Tomasoni S, Casiraghi F, Bonazzola S, Mister M, Sayegh MH, Remuzzi G.

J Immunol. 2000 May 1;164(9):4649-58.

48.

CTLA4Ig gene transfer prolongs survival and induces donor-specific tolerance in a rat renal allograft.

Tomasoni S, Azzollini N, Casiraghi F, Capogrossi MC, Remuzzi G, Benigni A.

J Am Soc Nephrol. 2000 Apr;11(4):747-52.

49.

Upregulation of renal and systemic cyclooxygenase-2 in patients with active lupus nephritis.

Tomasoni S, Noris M, Zappella S, Gotti E, Casiraghi F, Bonazzola S, Benigni A, Remuzzi G.

J Am Soc Nephrol. 1998 Jul;9(7):1202-12.

50.

Ultrastructural, histochemical and electrophysiological study of calf gallbladder epithelium.

Botta G, Tomasoni S, Riccardi D, Fucile F, Vitellaro-Zuccarello L.

Tissue Cell. 1994 Dec;26(6):827-39.

PMID:
7886672

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