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Items: 1 to 50 of 78

1.

Cancer prevention: Molecular and epidemiologic consensus.

Song M, Vogelstein B, Giovannucci EL, Willett WC, Tomasetti C.

Science. 2018 Sep 28;361(6409):1317-1318. doi: 10.1126/science.aau3830. No abstract available.

PMID:
30262488
2.

Eradicating Suicide at Its Roots: Preclinical Bases and Clinical Evidence of the Efficacy of Ketamine in the Treatment of Suicidal Behaviors.

De Berardis D, Fornaro M, Valchera A, Cavuto M, Perna G, Di Nicola M, Serafini G, Carano A, Pompili M, Vellante F, Orsolini L, Fiengo A, Ventriglio A, Yong-Ku K, Martinotti G, Di Giannantonio M, Tomasetti C.

Int J Mol Sci. 2018 Sep 23;19(10). pii: E2888. doi: 10.3390/ijms19102888. Review.

3.

Safety of antipsychotics for the treatment of schizophrenia: a focus on the adverse effects of clozapine.

De Berardis D, Rapini G, Olivieri L, Di Nicola D, Tomasetti C, Valchera A, Fornaro M, Di Fabio F, Perna G, Di Nicola M, Serafini G, Carano A, Pompili M, Vellante F, Orsolini L, Martinotti G, Di Giannantonio M.

Ther Adv Drug Saf. 2018 May;9(5):237-256. doi: 10.1177/2042098618756261. Epub 2018 Feb 6. Review.

4.

Evaluation of liquid from the Papanicolaou test and other liquid biopsies for the detection of endometrial and ovarian cancers.

Wang Y, Li L, Douville C, Cohen JD, Yen TT, Kinde I, Sundfelt K, Kjær SK, Hruban RH, Shih IM, Wang TL, Kurman RJ, Springer S, Ptak J, Popoli M, Schaefer J, Silliman N, Dobbyn L, Tanner EJ, Angarita A, Lycke M, Jochumsen K, Afsari B, Danilova L, Levine DA, Jardon K, Zeng X, Arseneau J, Fu L, Diaz LA Jr, Karchin R, Tomasetti C, Kinzler KW, Vogelstein B, Fader AN, Gilbert L, Papadopoulos N.

Sci Transl Med. 2018 Mar 21;10(433). pii: eaap8793. doi: 10.1126/scitranslmed.aap8793.

PMID:
29563323
5.

Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy.

Springer SU, Chen CH, Rodriguez Pena MDC, Li L, Douville C, Wang Y, Cohen JD, Taheri D, Silliman N, Schaefer J, Ptak J, Dobbyn L, Papoli M, Kinde I, Afsari B, Tregnago AC, Bezerra SM, VandenBussche C, Fujita K, Ertoy D, Cunha IW, Yu L, Bivalacqua TJ, Grollman AP, Diaz LA, Karchin R, Danilova L, Huang CY, Shun CT, Turesky RJ, Yun BH, Rosenquist TA, Pu YS, Hruban RH, Tomasetti C, Papadopoulos N, Kinzler KW, Vogelstein B, Dickman KG, Netto GJ.

Elife. 2018 Mar 20;7. pii: e32143. doi: 10.7554/eLife.32143.

6.

Nicotine and caffeine modulate haloperidol-induced changes in postsynaptic density transcripts expression: Translational insights in psychosis therapy and treatment resistance.

de Bartolomeis A, Iasevoli F, Marmo F, Buonaguro EF, Avvisati L, Latte G, Tomasetti C.

Eur Neuropsychopharmacol. 2018 Apr;28(4):538-559. doi: 10.1016/j.euroneuro.2018.01.006. Epub 2018 Feb 21.

PMID:
29475793
7.

Serial circulating tumour DNA analysis during multimodality treatment of locally advanced rectal cancer: a prospective biomarker study.

Tie J, Cohen JD, Wang Y, Li L, Christie M, Simons K, Elsaleh H, Kosmider S, Wong R, Yip D, Lee M, Tran B, Rangiah D, Burge M, Goldstein D, Singh M, Skinner I, Faragher I, Croxford M, Bampton C, Haydon A, Jones IT, S Karapetis C, Price T, Schaefer MJ, Ptak J, Dobbyn L, Silliman N, Kinde I, Tomasetti C, Papadopoulos N, Kinzler K, Volgestein B, Gibbs P.

Gut. 2018 Feb 2. pii: gutjnl-2017-315852. doi: 10.1136/gutjnl-2017-315852. [Epub ahead of print]

PMID:
29420226
8.

Detection and localization of surgically resectable cancers with a multi-analyte blood test.

Cohen JD, Li L, Wang Y, Thoburn C, Afsari B, Danilova L, Douville C, Javed AA, Wong F, Mattox A, Hruban RH, Wolfgang CL, Goggins MG, Dal Molin M, Wang TL, Roden R, Klein AP, Ptak J, Dobbyn L, Schaefer J, Silliman N, Popoli M, Vogelstein JT, Browne JD, Schoen RE, Brand RE, Tie J, Gibbs P, Wong HL, Mansfield AS, Jen J, Hanash SM, Falconi M, Allen PJ, Zhou S, Bettegowda C, Diaz LA Jr, Tomasetti C, Kinzler KW, Vogelstein B, Lennon AM, Papadopoulos N.

Science. 2018 Feb 23;359(6378):926-930. doi: 10.1126/science.aar3247. Epub 2018 Jan 18.

9.

Immediate-Early Genes Modulation by Antipsychotics: Translational Implications for a Putative Gateway to Drug-Induced Long-Term Brain Changes.

de Bartolomeis A, Buonaguro EF, Latte G, Rossi R, Marmo F, Iasevoli F, Tomasetti C.

Front Behav Neurosci. 2017 Dec 11;11:240. doi: 10.3389/fnbeh.2017.00240. eCollection 2017. Review.

10.

Combined circulating tumor DNA and protein biomarker-based liquid biopsy for the earlier detection of pancreatic cancers.

Cohen JD, Javed AA, Thoburn C, Wong F, Tie J, Gibbs P, Schmidt CM, Yip-Schneider MT, Allen PJ, Schattner M, Brand RE, Singhi AD, Petersen GM, Hong SM, Kim SC, Falconi M, Doglioni C, Weiss MJ, Ahuja N, He J, Makary MA, Maitra A, Hanash SM, Dal Molin M, Wang Y, Li L, Ptak J, Dobbyn L, Schaefer J, Silliman N, Popoli M, Goggins MG, Hruban RH, Wolfgang CL, Klein AP, Tomasetti C, Papadopoulos N, Kinzler KW, Vogelstein B, Lennon AM.

Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10202-10207. doi: 10.1073/pnas.1704961114. Epub 2017 Sep 5.

11.

Role of stem-cell divisions in cancer risk.

Tomasetti C, Durrett R, Kimmel M, Lambert A, Parmigiani G, Zauber A, Vogelstein B.

Nature. 2017 Aug 9;548(7666):E13-E14. doi: 10.1038/nature23302. No abstract available.

PMID:
28796214
12.

The burden of mood-disorder/cerebrovascular disease comorbidity: essential neurobiology, psychopharmacology, and physical activity interventions.

Fornaro M, Solmi M, Veronese N, De Berardis D, Buonaguro EF, Tomasetti C, Perna G, Preti A, Carta MG.

Int Rev Psychiatry. 2017 Oct;29(5):425-435. doi: 10.1080/09540261.2017.1299695. Epub 2017 Jul 6. Review.

PMID:
28681620
13.

On the slope of the regression between stem cell divisions and cancer risk, and the lack of correlation between stem cell divisions and environmental factors-associated cancer risk.

Tomasetti C, Vogelstein B.

PLoS One. 2017 May 16;12(5):e0175535. doi: 10.1371/journal.pone.0175535. eCollection 2017. No abstract available.

14.

Cancer-Associated Mutations in Endometriosis without Cancer.

Anglesio MS, Papadopoulos N, Ayhan A, Nazeran TM, Noë M, Horlings HM, Lum A, Jones S, Senz J, Seckin T, Ho J, Wu RC, Lac V, Ogawa H, Tessier-Cloutier B, Alhassan R, Wang A, Wang Y, Cohen JD, Wong F, Hasanovic A, Orr N, Zhang M, Popoli M, McMahon W, Wood LD, Mattox A, Allaire C, Segars J, Williams C, Tomasetti C, Boyd N, Kinzler KW, Gilks CB, Diaz L, Wang TL, Vogelstein B, Yong PJ, Huntsman DG, Shih IM.

N Engl J Med. 2017 May 11;376(19):1835-1848. doi: 10.1056/NEJMoa1614814.

15.

Stem cell divisions, somatic mutations, cancer etiology, and cancer prevention.

Tomasetti C, Li L, Vogelstein B.

Science. 2017 Mar 24;355(6331):1330-1334. doi: 10.1126/science.aaf9011.

16.

Re-arrangements of gene transcripts at glutamatergic synapses after prolonged treatments with antipsychotics: A putative link with synaptic remodeling.

Buonaguro EF, Iasevoli F, Marmo F, Eramo A, Latte G, Avagliano C, Tomasetti C, de Bartolomeis A.

Prog Neuropsychopharmacol Biol Psychiatry. 2017 Jun 2;76:29-41. doi: 10.1016/j.pnpbp.2017.02.012. Epub 2017 Feb 22.

PMID:
28235555
17.

The Role of Inhaled Loxapine in the Treatment of Acute Agitation in Patients with Psychiatric Disorders: A Clinical Review.

de Berardis D, Fornaro M, Orsolini L, Iasevoli F, Tomasetti C, de Bartolomeis A, Serroni N, Valchera A, Carano A, Vellante F, Marini S, Piersanti M, Perna G, Martinotti G, Di Giannantonio M.

Int J Mol Sci. 2017 Feb 8;18(2). pii: E349. doi: 10.3390/ijms18020349. Review.

18.

Treating the Synapse in Major Psychiatric Disorders: The Role of Postsynaptic Density Network in Dopamine-Glutamate Interplay and Psychopharmacologic Drugs Molecular Actions.

Tomasetti C, Iasevoli F, Buonaguro EF, De Berardis D, Fornaro M, Fiengo AL, Martinotti G, Orsolini L, Valchera A, Di Giannantonio M, de Bartolomeis A.

Int J Mol Sci. 2017 Jan 12;18(1). pii: E135. doi: 10.3390/ijms18010135. Review.

19.

Current and Future Perspectives on the Major Depressive Disorder: Focus on the New Multimodal Antidepressant Vortioxetine.

Orsolini L, Tomasetti C, Valchera A, Iasevoli F, Buonaguro EF, Fornaro M, Fiengo ALC, Martinotti G, Vellante F, Matarazzo I, Vecchiotti R, Perna G, Nicola MD, Carano A, Bartolomeis A, Giannantonio MD, Berardis D.

CNS Neurol Disord Drug Targets. 2017;16(1):65-92. doi: 10.2174/1871527315666161025140111. Review.

PMID:
27781949
20.

Effect of agomelatine treatment on C-reactive protein levels in patients with major depressive disorder: an exploratory study in "real-world," everyday clinical practice.

De Berardis D, Fornaro M, Orsolini L, Iasevoli F, Tomasetti C, de Bartolomeis A, Serroni N, De Lauretis I, Girinelli G, Mazza M, Valchera A, Carano A, Vellante F, Matarazzo I, Perna G, Martinotti G, Di Giannantonio M.

CNS Spectr. 2017 Aug;22(4):342-347. doi: 10.1017/S1092852916000572. Epub 2016 Oct 5.

PMID:
27702411
21.

STARTING ARIPIPRAZOLE LONG-ACTING-ONCE-A-MONTH EARLY IN TREATMENT: WHY, HOW AND FOR WHOM? EXPERT CONSENSUS AND PRACTICAL RECOMMENDATIONS BY A PANEL OF ITALIAN CLINICIANS.

Amodeo G, Candiracci C, Capecci I, De Filippis S, Giuliani S, Guerani G, Tomasetti C, Villari V, Fagiolini A.

Expert Opin Pharmacother. 2016 Oct 3. [Epub ahead of print]

PMID:
27690670
22.

Suicide during Perinatal Period: Epidemiology, Risk Factors, and Clinical Correlates.

Orsolini L, Valchera A, Vecchiotti R, Tomasetti C, Iasevoli F, Fornaro M, De Berardis D, Perna G, Pompili M, Bellantuono C.

Front Psychiatry. 2016 Aug 12;7:138. doi: 10.3389/fpsyt.2016.00138. eCollection 2016. Review.

23.

Genome-wide quantification of rare somatic mutations in normal human tissues using massively parallel sequencing.

Hoang ML, Kinde I, Tomasetti C, McMahon KW, Rosenquist TA, Grollman AP, Kinzler KW, Vogelstein B, Papadopoulos N.

Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):9846-51. doi: 10.1073/pnas.1607794113. Epub 2016 Aug 15.

24.

Postsynaptic density protein transcripts are differentially modulated by minocycline alone or in add-on to haloperidol: Implications for treatment resistant schizophrenia.

Buonaguro EF, Tomasetti C, Chiodini P, Marmo F, Latte G, Rossi R, Avvisati L, Iasevoli F, de Bartolomeis A.

J Psychopharmacol. 2017 Apr;31(4):406-417. doi: 10.1177/0269881116658987. Epub 2016 Jul 19.

PMID:
27443599
25.

Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer.

Tie J, Wang Y, Tomasetti C, Li L, Springer S, Kinde I, Silliman N, Tacey M, Wong HL, Christie M, Kosmider S, Skinner I, Wong R, Steel M, Tran B, Desai J, Jones I, Haydon A, Hayes T, Price TJ, Strausberg RL, Diaz LA Jr, Papadopoulos N, Kinzler KW, Vogelstein B, Gibbs P.

Sci Transl Med. 2016 Jul 6;8(346):346ra92. doi: 10.1126/scitranslmed.aaf6219.

26.

An update of safety of clinically used atypical antipsychotics.

Orsolini L, Tomasetti C, Valchera A, Vecchiotti R, Matarazzo I, Vellante F, Iasevoli F, Buonaguro EF, Fornaro M, Fiengo AL, Martinotti G, Mazza M, Perna G, Carano A, De Bartolomeis A, Di Giannantonio M, De Berardis D.

Expert Opin Drug Saf. 2016 Oct;15(10):1329-47. doi: 10.1080/14740338.2016.1201475. Epub 2016 Jul 4. Review.

PMID:
27347638
27.

Switching antipsychotics: Imaging the differential effect on the topography of postsynaptic density transcripts in antipsychotic-naïve vs. antipsychotic-exposed rats.

de Bartolomeis A, Marmo F, Buonaguro EF, Latte G, Tomasetti C, Iasevoli F.

Prog Neuropsychopharmacol Biol Psychiatry. 2016 Oct 3;70:24-38. doi: 10.1016/j.pnpbp.2016.04.015. Epub 2016 May 10.

PMID:
27177972
28.

New advances in the treatment of generalized anxiety disorder: the multimodal antidepressant vortioxetine.

Orsolini L, Tomasetti C, Valchera A, Iasevoli F, Buonaguro EF, Vellante F, Fornaro M, Fiengo A, Mazza M, Vecchiotti R, Perna G, de Bartolomeis A, Martinotti G, Di Giannantonio M, De Berardis D.

Expert Rev Neurother. 2016 May;16(5):483-95. doi: 10.1586/14737175.2016.1173545. Epub 2016 Apr 18. Review.

PMID:
27050932
29.

Update on the Mechanism of Action of Aripiprazole: Translational Insights into Antipsychotic Strategies Beyond Dopamine Receptor Antagonism.

de Bartolomeis A, Tomasetti C, Iasevoli F.

CNS Drugs. 2015 Sep;29(9):773-99. doi: 10.1007/s40263-015-0278-3. Review.

30.

Treatment resistant schizophrenia is associated with the worst community functioning among severely-ill highly-disabling psychiatric conditions and is the most relevant predictor of poorer achievements in functional milestones.

Iasevoli F, Giordano S, Balletta R, Latte G, Formato MV, Prinzivalli E, De Berardis D, Tomasetti C, de Bartolomeis A.

Prog Neuropsychopharmacol Biol Psychiatry. 2016 Feb 4;65:34-48. doi: 10.1016/j.pnpbp.2015.08.010. Epub 2015 Aug 25.

PMID:
26320028
31.

A comprehensive review on the efficacy of S-Adenosyl-L-methionine in Major Depressive Disorder.

De Berardis D, Orsolini L, Serroni N, Girinelli G, Iasevoli F, Tomasetti C, de Bartolomeis A, Mazza M, Valchera A, Fornaro M, Perna G, Piersanti M, Di Nicola M, Cavuto M, Martinotti G, Di Giannantonio M.

CNS Neurol Disord Drug Targets. 2016;15(1):35-44. Review.

PMID:
26295824
32.

D-aspartate dysregulation in Ddo(-/-) mice modulates phencyclidine-induced gene expression changes of postsynaptic density molecules in cortex and striatum.

de Bartolomeis A, Errico F, Aceto G, Tomasetti C, Usiello A, Iasevoli F.

Prog Neuropsychopharmacol Biol Psychiatry. 2015 Oct 1;62:35-43. doi: 10.1016/j.pnpbp.2015.05.003. Epub 2015 May 12.

PMID:
25979765
33.

Targeting the Noradrenergic System in Posttraumatic Stress Disorder: A Systematic Review and Meta-Analysis of Prazosin Trials.

De Berardis D, Marini S, Serroni N, Iasevoli F, Tomasetti C, de Bartolomeis A, Mazza M, Tempesta D, Valchera A, Fornaro M, Pompili M, Sepede G, Vellante F, Orsolini L, Martinotti G, Di Giannantonio M.

Curr Drug Targets. 2015;16(10):1094-106. Review.

PMID:
25944011
34.

Factor structure and reliability of the Italian adaptation of the Hypomania Check List-32, second revision (HCL-32-R2).

Fornaro M, De Berardis D, Mazza M, Pino M, Favaretto E, Bedani F, Wieser C, Indelicato L, Paternò VF, Lo Monaco F, Dugo F, Ventriglio A, Mungo S, Selle V, Valchera A, Elassy M, Martinotti G, De Bartolomeis A, Iasevoli F, Tomasetti C, Avvisati L, Tartaglione S, Perna G, Cattaneo CI, Consoli G, Romano A, Del Debbio A, Martino M, D' Angelo E, De Pasquale C, Koshy AS, Angst J.

J Affect Disord. 2015 Jun 1;178:112-20. doi: 10.1016/j.jad.2015.03.001. Epub 2015 Mar 10.

PMID:
25805403
35.

The (not so) immortal strand hypothesis.

Tomasetti C, Bozic I.

Stem Cell Res. 2015 Mar;14(2):238-41. doi: 10.1016/j.scr.2015.01.005. Epub 2015 Jan 24.

36.

Cancer risk: role of environment—response.

Tomasetti C, Vogelstein B.

Science. 2015 Feb 13;347(6223):729-31. doi: 10.1126/science.aaa6592. Epub 2015 Feb 5. No abstract available.

PMID:
25678653
37.

Progressive recruitment of cortical and striatal regions by inducible postsynaptic density transcripts after increasing doses of antipsychotics with different receptor profiles: insights for psychosis treatment.

de Bartolomeis A, Iasevoli F, Marmo F, Buonaguro EF, Eramo A, Rossi R, Avvisati L, Latte G, Tomasetti C.

Eur Neuropsychopharmacol. 2015 Apr;25(4):566-82. doi: 10.1016/j.euroneuro.2015.01.003. Epub 2015 Jan 15.

PMID:
25649681
38.

Alexithymia, responsibility attitudes and suicide ideation among outpatients with obsessive-compulsive disorder: an exploratory study.

De Berardis D, Serroni N, Campanella D, Rapini G, Olivieri L, Feliziani B, Carano A, Valchera A, Iasevoli F, Tomasetti C, Mazza M, Fornaro M, Perna G, Di Nicola M, Martinotti G, Di Giannantonio M.

Compr Psychiatry. 2015 Apr;58:82-7. doi: 10.1016/j.comppsych.2014.12.016. Epub 2014 Dec 30.

PMID:
25591904
39.

Agomelatine beyond borders: current evidences of its efficacy in disorders other than major depression.

De Berardis D, Fornaro M, Serroni N, Campanella D, Rapini G, Olivieri L, Srinivasan V, Iasevoli F, Tomasetti C, De Bartolomeis A, Valchera A, Perna G, Mazza M, Di Nicola M, Martinotti G, Di Giannantonio M.

Int J Mol Sci. 2015 Jan 5;16(1):1111-30. doi: 10.3390/ijms16011111. Review.

40.

Cancer etiology. Variation in cancer risk among tissues can be explained by the number of stem cell divisions.

Tomasetti C, Vogelstein B.

Science. 2015 Jan 2;347(6217):78-81. doi: 10.1126/science.1260825.

41.

Only three driver gene mutations are required for the development of lung and colorectal cancers.

Tomasetti C, Marchionni L, Nowak MA, Parmigiani G, Vogelstein B.

Proc Natl Acad Sci U S A. 2015 Jan 6;112(1):118-23. doi: 10.1073/pnas.1421839112. Epub 2014 Dec 22.

42.

Drug resistance.

Tomasetti C.

Adv Exp Med Biol. 2014;844:303-16. doi: 10.1007/978-1-4939-2095-2_15. Review.

PMID:
25480648
43.

MicroRNAs in Schizophrenia: Implications for Synaptic Plasticity and Dopamine-Glutamate Interaction at the Postsynaptic Density. New Avenues for Antipsychotic Treatment Under a Theranostic Perspective.

de Bartolomeis A, Iasevoli F, Tomasetti C, Buonaguro EF.

Mol Neurobiol. 2015 Dec;52(3):1771-1790. doi: 10.1007/s12035-014-8962-8. Epub 2014 Nov 14. Review.

PMID:
25394379
44.

An argument for mechanism-based statistical inference in cancer.

Geman D, Ochs M, Price ND, Tomasetti C, Younes L.

Hum Genet. 2015 May;134(5):479-95. doi: 10.1007/s00439-014-1501-x. Epub 2014 Nov 9. Review.

45.

Prevalence and clinical features associated to bipolar disorder-migraine comorbidity: a systematic review.

Fornaro M, De Berardis D, De Pasquale C, Indelicato L, Pollice R, Valchera A, Perna G, Iasevoli F, Tomasetti C, Martinotti G, Koshy AS, Fasmer OB, Oedegaard KJ.

Compr Psychiatry. 2015 Jan;56:1-16. doi: 10.1016/j.comppsych.2014.09.020. Epub 2014 Sep 28. Review.

PMID:
25306379
46.

Regulation of postsynaptic plasticity genes' expression and topography by sustained dopamine perturbation and modulation by acute memantine: relevance to schizophrenia.

Iasevoli F, Buonaguro EF, Sarappa C, Marmo F, Latte G, Rossi R, Eramo A, Tomasetti C, de Bartolomeis A.

Prog Neuropsychopharmacol Biol Psychiatry. 2014 Oct 3;54:299-314. doi: 10.1016/j.pnpbp.2014.07.003. Epub 2014 Jul 12.

PMID:
25025505
47.

The glutamatergic aspects of schizophrenia molecular pathophysiology: role of the postsynaptic density, and implications for treatment.

Iasevoli F, Tomasetti C, Buonaguro EF, de Bartolomeis A.

Curr Neuropharmacol. 2014 May;12(3):219-38. doi: 10.2174/1570159X12666140324183406.

48.

Why tyrosine kinase inhibitor resistance is common in advanced gastrointestinal stromal tumors.

Tomasetti C, Demetri GD, Parmigiani G.

F1000Res. 2013 Jul 9;2:152. doi: 10.12688/f1000research.2-152.v1. eCollection 2013.

49.

The emerging role of dopamine-glutamate interaction and of the postsynaptic density in bipolar disorder pathophysiology: Implications for treatment.

de Bartolomeis A, Buonaguro EF, Iasevoli F, Tomasetti C.

J Psychopharmacol. 2014 Jun;28(6):505-26. doi: 10.1177/0269881114523864. Epub 2014 Feb 19. Review.

PMID:
24554693
50.

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