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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 1
1990 1
1991 1
1992 1
1993 2
1994 1
1995 2
1997 1
1998 4
1999 4
2000 8
2001 3
2002 5
2003 9
2004 9
2005 10
2006 7
2007 8
2008 9
2009 8
2010 7
2011 7
2012 7
2013 10
2014 4
2015 8
2016 8
2017 9
2018 6
2019 16
2020 6
2021 8
2022 16
2023 8
2024 0

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203 results

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Page 1
TOM1 family conservation within the plant kingdom for tobacco mosaic virus accumulation.
Zhang H, Hu Q. Zhang H, et al. Mol Plant Pathol. 2023 Nov;24(11):1385-1399. doi: 10.1111/mpp.13375. Epub 2023 Jul 13. Mol Plant Pathol. 2023. PMID: 37443447 Free PMC article.
Evolutionary analysis revealed that the TOM1 family is restricted to the plant kingdom and probably originated in the Chlorophyta division, suggesting an ancient origin of the TOM1 family. ...Moreover, the capacity of TOM1 orthologues from different plant spe …
Evolutionary analysis revealed that the TOM1 family is restricted to the plant kingdom and probably originated in the Chlorophyta div …
Protein Trafficking or Cell Signaling: A Dilemma for the Adaptor Protein TOM1.
Roach TG, Lång HKM, Xiong W, Ryhänen SJ, Capelluto DGS. Roach TG, et al. Front Cell Dev Biol. 2021 Feb 26;9:643769. doi: 10.3389/fcell.2021.643769. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33718385 Free PMC article. Review.
Several ESCRT proteins, including TOLLIP, Endofin, and Hrs, have been reported to form a complex with TOM1 at early endosomal membrane surfaces, which may potentiate the role of TOM1 in cargo sorting. ...Based on current knowledge of TOM1-dependent cellular p …
Several ESCRT proteins, including TOLLIP, Endofin, and Hrs, have been reported to form a complex with TOM1 at early endosomal membran …
Multifaceted roles of TAX1BP1 in autophagy.
White J, Suklabaidya S, Vo MT, Choi YB, Harhaj EW. White J, et al. Autophagy. 2023 Jan;19(1):44-53. doi: 10.1080/15548627.2022.2070331. Epub 2022 May 9. Autophagy. 2023. PMID: 35470757 Free PMC article. Review.
In this review, we will discuss and integrate recent findings related to the autophagy function of TAX1BP1 and highlight outstanding questions regarding its functions in autophagy and regulation of innate immunity and host defense.Abbreviations: ATG: autophagy related; CALCOCO: c …
In this review, we will discuss and integrate recent findings related to the autophagy function of TAX1BP1 and highlight outstanding questio …
Amyloid-beta impairs TOM1-mediated IL-1R1 signaling.
Martini AC, Gomez-Arboledas A, Forner S, Rodriguez-Ortiz CJ, McQuade A, Danhash E, Phan J, Javonillo D, Ha JV, Tram M, Trujillo-Estrada L, da Cunha C, Ager RR, Davila JC, Kitazawa M, Blurton-Jones M, Gutierrez A, Baglietto-Vargas D, Medeiros R, LaFerla FM. Martini AC, et al. Proc Natl Acad Sci U S A. 2019 Oct 15;116(42):21198-21206. doi: 10.1073/pnas.1914088116. Epub 2019 Sep 30. Proc Natl Acad Sci U S A. 2019. PMID: 31570577 Free PMC article.
We first show that TOM1 steady-state levels are reduced in human AD hippocampi and in the brain of an AD mouse model versus respective controls. ...These data show that reparation of the TOM1-signaling pathway represents a therapeutic target for brain inflammatory d …
We first show that TOM1 steady-state levels are reduced in human AD hippocampi and in the brain of an AD mouse model versus respectiv …
Reduction in TOM1 expression exacerbates Alzheimer's disease.
Peng J, Zhao T. Peng J, et al. Proc Natl Acad Sci U S A. 2020 Feb 25;117(8):3915-3916. doi: 10.1073/pnas.1917589117. Epub 2020 Feb 11. Proc Natl Acad Sci U S A. 2020. PMID: 32047041 Free PMC article. No abstract available.
SENP1 modulates chronic intermittent hypoxia-induced inflammation of microglia and neuronal injury by inhibiting TOM1 pathway.
Wang H, Wang X, Shen Y, Wang Y, Yang T, Sun J, Liu S. Wang H, et al. Int Immunopharmacol. 2023 Jun;119:110230. doi: 10.1016/j.intimp.2023.110230. Epub 2023 May 1. Int Immunopharmacol. 2023. PMID: 37137262 Free article.
After SENP1 overexpression in vitro, the enhanced SUMOylation of TOM1 was inhibited; the level of TOM1 and microglial migration were enhanced; neuroinflammation, neuronal Abeta(42) deposition and apoptosis were significantly reduced. However, the administration of s …
After SENP1 overexpression in vitro, the enhanced SUMOylation of TOM1 was inhibited; the level of TOM1 and microglial migratio …
Tom1 (target of Myb 1) is a novel negative regulator of interleukin-1- and tumor necrosis factor-induced signaling pathways.
Yamakami M, Yokosawa H. Yamakami M, et al. Biol Pharm Bull. 2004 Apr;27(4):564-6. doi: 10.1248/bpb.27.564. Biol Pharm Bull. 2004. PMID: 15056867 Free article.
The Tom1 (target of Myb 1) protein has VHS and GAT domains in N-terminal and central parts, respectively. ...In this study, we carried out a reporter gene assay to investigate the function of Tom1 in inflammatory cytokine-dependent signaling. It was found that overe …
The Tom1 (target of Myb 1) protein has VHS and GAT domains in N-terminal and central parts, respectively. ...In this study, we carrie …
The Penicillium chrysogenum tom1 Gene a Major Target of Transcription Factor MAT1-1-1 Encodes a Nuclear Protein Involved in Sporulation.
Ramšak B, Kück U. Ramšak B, et al. Front Fungal Biol. 2022 Jul 14;3:937023. doi: 10.3389/ffunb.2022.937023. eCollection 2022. Front Fungal Biol. 2022. PMID: 37746180 Free PMC article.
Using fluorescence microscopy, we demonstrated binding of MAT1-1-1 to the tom1 promoter by reporter gene analysis. Extensive electrophoretic mobility shift assays (EMSAs) further showed that the promoter sequence of tom1 is bound in vitro by both MAT1-1-1 and MAT1-2 …
Using fluorescence microscopy, we demonstrated binding of MAT1-1-1 to the tom1 promoter by reporter gene analysis. Extensive electrop …
Endofin recruits TOM1 to endosomes.
Seet LF, Liu N, Hanson BJ, Hong W. Seet LF, et al. J Biol Chem. 2004 Feb 6;279(6):4670-9. doi: 10.1074/jbc.M311228200. Epub 2003 Nov 12. J Biol Chem. 2004. PMID: 14613930 Free article.
Neither SARA nor Hrs, two other FYVE domain proteins, interact with this region of TOM1. Moreover, endofin does not interact with the analogous region of two other members of the TOM1 protein family, namely, TOM1-like 1 (TOM1-L1) or TOM1-like 2 …
Neither SARA nor Hrs, two other FYVE domain proteins, interact with this region of TOM1. Moreover, endofin does not interact with the …
Emerging views of OPTN (optineurin) function in the autophagic process associated with disease.
Qiu Y, Wang J, Li H, Yang B, Wang J, He Q, Weng Q. Qiu Y, et al. Autophagy. 2022 Jan;18(1):73-85. doi: 10.1080/15548627.2021.1908722. Epub 2021 Apr 13. Autophagy. 2022. PMID: 33783320 Free PMC article. Review.
A comprehensive review of the function of OPTN in autophagy provides valuable insight into the pathogenesis of human diseases related to OPTN and facilitates the discovery of potential key regulators and novel therapeutic targets for disease intervention in patients with autophag …
A comprehensive review of the function of OPTN in autophagy provides valuable insight into the pathogenesis of human diseases related to OPT …
203 results