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Items: 33

1.

Cytokeratin-Supervised Deep Learning for Automatic Recognition of Epithelial Cells in Breast Cancers Stained for ER, PR, and Ki-67.

Valkonen M, Isola J, Ylinen O, Muhonen V, Saxlin A, Tolonen T, Nykter M, Ruusuvuori P.

IEEE Trans Med Imaging. 2020 Feb;39(2):534-542. doi: 10.1109/TMI.2019.2933656. Epub 2019 Aug 7.

PMID:
31398111
2.

Treatment of keloid scars with intralesional triamcinolone and 5-fluorouracil injections - a randomized controlled trial.

Hietanen KE, Järvinen TA, Huhtala H, Tolonen TT, Kuokkanen HO, Kaartinen IS.

J Plast Reconstr Aesthet Surg. 2019 Jan;72(1):4-11. doi: 10.1016/j.bjps.2018.05.052. Epub 2018 Jun 25.

PMID:
30448246
3.

Identification of breast tumors from diathermy smoke by differential ion mobility spectrometry.

Sutinen M, Kontunen A, Karjalainen M, Kiiski J, Hannus J, Tolonen T, Roine A, Oksala N.

Eur J Surg Oncol. 2019 Feb;45(2):141-146. doi: 10.1016/j.ejso.2018.09.005. Epub 2018 Oct 15.

PMID:
30366874
4.

Atorvastatin Versus Placebo for Prostate Cancer Before Radical Prostatectomy-A Randomized, Double-blind, Placebo-controlled Clinical Trial.

Murtola TJ, Syvälä H, Tolonen T, Helminen M, Riikonen J, Koskimäki J, Pakarainen T, Kaipia A, Isotalo T, Kujala P, Tammela TLJ.

Eur Urol. 2018 Dec;74(6):697-701. doi: 10.1016/j.eururo.2018.06.037. Epub 2018 Jul 18.

PMID:
30031572
5.

Disposable electrochemical immunosensor for cortisol determination in human saliva.

Kämäräinen S, Mäki M, Tolonen T, Palleschi G, Virtanen V, Micheli L, Sesay AM.

Talanta. 2018 Oct 1;188:50-57. doi: 10.1016/j.talanta.2018.05.039. Epub 2018 May 16.

PMID:
30029405
6.

Optimized JPEG 2000 Compression for Efficient Storage of Histopathological Whole-Slide Images.

Helin H, Tolonen T, Ylinen O, Tolonen P, Näpänkangas J, Isola J.

J Pathol Inform. 2018 May 25;9:20. doi: 10.4103/jpi.jpi_69_17. eCollection 2018.

7.

Extraprostatic extension (pT3a) in prostate biopsy is an under-recognized feature indicating high risk disease.

Tolonen TT, Riikonen J, Tammela TLJ, Koivusalo L, Haapasalo H, Kujala P, Kaipia A.

Ann Diagn Pathol. 2018 Aug;35:80-84. doi: 10.1016/j.anndiagpath.2018.06.001. Epub 2018 Jun 5. No abstract available.

PMID:
29886397
8.

Expression of neuroendocrine differentiation markers in lethal metastatic castration-resistant prostate cancer.

Sainio M, Visakorpi T, Tolonen T, Ilvesaro J, Bova GS.

Pathol Res Pract. 2018 Jun;214(6):848-856. doi: 10.1016/j.prp.2018.04.015. Epub 2018 Apr 26.

PMID:
29728311
9.

Digital image analysis of the tissue surface areas of site-designated and bilaterally pooled prostate biopsies.

Koivusalo L, Kaipia A, Kujala P, Isola J, Tolonen TT.

Histol Histopathol. 2018 Apr;33(4):399-405. doi: 10.14670/HH-11-940. Epub 2017 Oct 23.

PMID:
29058306
10.

Feasibility of Prostate PAXgene Fixation for Molecular Research and Diagnostic Surgical Pathology: Comparison of Matched Fresh Frozen, FFPE, and PFPE Tissues.

Högnäs G, Kivinummi K, Kallio HML, Hieta R, Ruusuvuori P, Koskenalho A, Kesseli J, Tammela TLJ, Riikonen J, Ilvesaro J, Kares S, Hirvikoski PP, Laurila M, Mirtti T, Nykter M, Kujala PM, Visakorpi T, Tolonen T, Bova GS.

Am J Surg Pathol. 2018 Jan;42(1):103-115. doi: 10.1097/PAS.0000000000000961.

PMID:
28984675
11.

Androgen Receptor Deregulation Drives Bromodomain-Mediated Chromatin Alterations in Prostate Cancer.

Urbanucci A, Barfeld SJ, Kytölä V, Itkonen HM, Coleman IM, Vodák D, Sjöblom L, Sheng X, Tolonen T, Minner S, Burdelski C, Kivinummi KK, Kohvakka A, Kregel S, Takhar M, Alshalalfa M, Davicioni E, Erho N, Lloyd P, Karnes RJ, Ross AE, Schaeffer EM, Vander Griend DJ, Knapp S, Corey E, Feng FY, Nelson PS, Saatcioglu F, Knudsen KE, Tammela TLJ, Sauter G, Schlomm T, Nykter M, Visakorpi T, Mills IG.

Cell Rep. 2017 Jun 6;19(10):2045-2059. doi: 10.1016/j.celrep.2017.05.049.

12.

Development of a fermented quinoa-based beverage.

Ludena Urquizo FE, García Torres SM, Tolonen T, Jaakkola M, Pena-Niebuhr MG, von Wright A, Repo-Carrasco-Valencia R, Korhonen H, Plumed-Ferrer C.

Food Sci Nutr. 2016 Oct 28;5(3):602-608. doi: 10.1002/fsn3.436. eCollection 2017 May.

13.

Integrated clinical, whole-genome, and transcriptome analysis of multisampled lethal metastatic prostate cancer.

Bova GS, Kallio HM, Annala M, Kivinummi K, Högnäs G, Häyrynen S, Rantapero T, Kivinen V, Isaacs WB, Tolonen T, Nykter M, Visakorpi T.

Cold Spring Harb Mol Case Stud. 2016 May;2(3):a000752. doi: 10.1101/mcs.a000752.

14.

Microseminoprotein-Beta Expression in Different Stages of Prostate Cancer.

Sjöblom L, Saramäki O, Annala M, Leinonen K, Nättinen J, Tolonen T, Wahlfors T, Nykter M, Bova GS, Schleutker J, Tammela TL, Lilja H, Visakorpi T.

PLoS One. 2016 Mar 3;11(3):e0150241. doi: 10.1371/journal.pone.0150241. eCollection 2016. Erratum in: PLoS One. 2016;11(4):e0153732.

15.

[Clinical pathology on the verge of virtual microscopy].

Tolonen T, Näpänkangas J, Isola J.

Duodecim. 2015;131(21):1981-7. Finnish.

PMID:
26677548
16.

CIP2A is a candidate therapeutic target in clinically challenging prostate cancer cell populations.

Khanna A, Rane JK, Kivinummi KK, Urbanucci A, Helenius MA, Tolonen TT, Saramäki OR, Latonen L, Manni V, Pimanda JE, Maitland NJ, Westermarck J, Visakorpi T.

Oncotarget. 2015 Aug 14;6(23):19661-70.

17.

Length of prostate biopsies is not necessarily compromised by pooling multiple cores in one paraffin block: an observational study.

Tolonen TT, Isola J, Kaipia A, Riikonen J, Koivusalo L, Huovinen S, Laurila M, Porre S, Tirkkonen M, Kujala P.

BMC Clin Pathol. 2015 Mar 8;15:4. doi: 10.1186/s12907-015-0001-9. eCollection 2015.

18.

Phenolic acid composition, antiatherogenic and anticancer potential of honeys derived from various regions in Greece.

Spilioti E, Jaakkola M, Tolonen T, Lipponen M, Virtanen V, Chinou I, Kassi E, Karabournioti S, Moutsatsou P.

PLoS One. 2014 Apr 21;9(4):e94860. doi: 10.1371/journal.pone.0094860. eCollection 2014.

19.

Quantitative analysis of γ-H2AX and p53 nuclear expression levels in ovarian and fallopian tube epithelium from risk-reducing salpingo-oophorectomies in BRCA1 and BRCA2 mutation carriers.

Staff S, Tolonen T, Laasanen SL, Mecklin JP, Isola J, Mäenpää J.

Int J Gynecol Pathol. 2014 May;33(3):309-16. doi: 10.1097/PGP.0b013e31829c673b.

PMID:
24681744
20.

Loss of PTEN is associated with aggressive behavior in ERG-positive prostate cancer.

Leinonen KA, Saramäki OR, Furusato B, Kimura T, Takahashi H, Egawa S, Suzuki H, Keiger K, Ho Hahm S, Isaacs WB, Tolonen TT, Stenman UH, Tammela TL, Nykter M, Bova GS, Visakorpi T.

Cancer Epidemiol Biomarkers Prev. 2013 Dec;22(12):2333-44. doi: 10.1158/1055-9965.EPI-13-0333-T. Epub 2013 Oct 1.

21.

ImmunoMembrane: a publicly available web application for digital image analysis of HER2 immunohistochemistry.

Tuominen VJ, Tolonen TT, Isola J.

Histopathology. 2012 Apr;60(5):758-67. doi: 10.1111/j.1365-2559.2011.04142.x. Epub 2012 Feb 1.

PMID:
22296215
22.

Overall and worst gleason scores are equally good predictors of prostate cancer progression.

Tolonen TT, Kujala PM, Tammela TL, Tuominen VJ, Isola JJ, Visakorpi T.

BMC Urol. 2011 Oct 6;11:21. doi: 10.1186/1471-2490-11-21.

23.

Histopathological variables and biomarkers enhancer of zeste homologue 2, Ki-67 and minichromosome maintenance protein 7 as prognosticators in primarily endocrine-treated prostate cancer.

Tolonen TT, Tammela TL, Kujala PM, Tuominen VJ, Isola JJ, Visakorpi T.

BJU Int. 2011 Nov;108(9):1430-8. doi: 10.1111/j.1464-410X.2011.10253.x. Epub 2011 May 18.

24.

Routine dual-color immunostaining with a 3-antibody cocktail improves the detection of small cancers in prostate needle biopsies.

Tolonen TT, Kujala PM, Laurila M, Tirkkonen M, Ilvesaro J, Tuominen VJ, Tammela TL, Isola J.

Hum Pathol. 2011 Nov;42(11):1635-42. doi: 10.1016/j.humpath.2010.12.021. Epub 2011 Apr 15.

PMID:
21497369
25.

Association of SPINK1 expression and TMPRSS2:ERG fusion with prognosis in endocrine-treated prostate cancer.

Leinonen KA, Tolonen TT, Bracken H, Stenman UH, Tammela TL, Saramäki OR, Visakorpi T.

Clin Cancer Res. 2010 May 15;16(10):2845-51. doi: 10.1158/1078-0432.CCR-09-2505. Epub 2010 May 4.

26.

A pure primary low-grade neuroendocrine carcinoma (carcinoid tumor) of the prostate.

Giordano S, Tolonen T, Tolonen T, Hirsimäki S, Kataja V.

Int Urol Nephrol. 2010 Sep;42(3):683-7. doi: 10.1007/s11255-009-9660-8. Epub 2009 Oct 29.

PMID:
19866370
27.

Comparative study of sugar fermentation and protein expression patterns of two Lactobacillus plantarum strains grown in three different media.

Plumed-Ferrer C, Koistinen KM, Tolonen TL, Lehesranta SJ, Kärenlampi SO, Mäkimattila E, Joutsjoki V, Virtanen V, von Wright A.

Appl Environ Microbiol. 2008 Sep;74(17):5349-58. doi: 10.1128/AEM.00324-08. Epub 2008 Jun 20.

28.

EZH2, Ki-67 and MCM7 are prognostic markers in prostatectomy treated patients.

Laitinen S, Martikainen PM, Tolonen T, Isola J, Tammela TL, Visakorpi T.

Int J Cancer. 2008 Feb 1;122(3):595-602.

29.

Bax and Bcl-2 are focally overexpressed in the normal epithelium of cancerous prostates.

Tolonen TT, Tommola S, Jokinen S, Parviainen T, Martikainen PM.

Scand J Urol Nephrol. 2007;41(2):85-90.

PMID:
17454944
30.

Reindeer beta-lactoglobulin crystal structure with pseudo-body-centred noncrystallographic symmetry.

Oksanen E, Jaakola VP, Tolonen T, Valkonen K, Akerström B, Kalkkinen N, Virtanen V, Goldman A.

Acta Crystallogr D Biol Crystallogr. 2006 Nov;62(Pt 11):1369-74. Epub 2006 Oct 18.

PMID:
17057340
31.

Dual-specificity phosphatase 1 and serum/glucocorticoid-regulated kinase are downregulated in prostate cancer.

Rauhala HE, Porkka KP, Tolonen TT, Martikainen PM, Tammela TL, Visakorpi T.

Int J Cancer. 2005 Dec 10;117(5):738-45.

32.

Synthesis and CB1 receptor activities of novel arachidonyl alcohol derivatives.

Parkkari T, Savinainen JR, Rauhala AL, Tolonen TL, Nevalainen T, Laitinen JT, Gynther J, Järvinen T.

Bioorg Med Chem Lett. 2004 Jun 21;14(12):3231-4.

PMID:
15149681
33.

Caries preventive effect of fluoride varnish applications performed two or four times a year.

Seppä L, Tolonen T.

Scand J Dent Res. 1990 Apr;98(2):102-5.

PMID:
2343272

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