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Items: 1 to 50 of 126


Effects of SAHA and EGCG on Growth Potentiation of Triple-Negative Breast Cancer Cells.

Lewis KA, Jordan HR, Tollefsbol TO.

Cancers (Basel). 2018 Dec 27;11(1). pii: E23. doi: 10.3390/cancers11010023.


The Effects of Combinatorial Genistein and Sulforaphane in Breast Tumor Inhibition: Role in Epigenetic Regulation.

Paul B, Li Y, Tollefsbol TO.

Int J Mol Sci. 2018 Jun 13;19(6). pii: E1754. doi: 10.3390/ijms19061754.


Withaferin A and sulforaphane regulate breast cancer cell cycle progression through epigenetic mechanisms.

Royston KJ, Paul B, Nozell S, Rajbhandari R, Tollefsbol TO.

Exp Cell Res. 2018 Jul 1;368(1):67-74. doi: 10.1016/j.yexcr.2018.04.015. Epub 2018 Apr 22.


The Role of Non-Coding RNAs and Isothiocyanates in Cancer.

Martin SL, Royston KJ, Tollefsbol TO.

Mol Nutr Food Res. 2018 Sep;62(18):e1700913. doi: 10.1002/mnfr.201700913. Epub 2018 May 28. Review.


Impact of genistein on the gut microbiome of humanized mice and its role in breast tumor inhibition.

Paul B, Royston KJ, Li Y, Stoll ML, Skibola CF, Wilson LS, Barnes S, Morrow CD, Tollefsbol TO.

PLoS One. 2017 Dec 21;12(12):e0189756. doi: 10.1371/journal.pone.0189756. eCollection 2017.


Epigenetic biomarkers: Current strategies and future challenges for their use in the clinical laboratory.

García-Giménez JL, Seco-Cervera M, Tollefsbol TO, Romá-Mateo C, Peiró-Chova L, Lapunzina P, Pallardó FV.

Crit Rev Clin Lab Sci. 2017 Nov - Dec;54(7-8):529-550. doi: 10.1080/10408363.2017.1410520. Epub 2017 Dec 11. Review.


Pterostilbene down-regulates hTERT at physiological concentrations in breast cancer cells: Potentially through the inhibition of cMyc.

Daniel M, Tollefsbol TO.

J Cell Biochem. 2018 Apr;119(4):3326-3337. doi: 10.1002/jcb.26495. Epub 2017 Dec 26.


The influence of an epigenetics diet on the cancer epigenome.

Lewis KA, Tollefsbol TO.

Epigenomics. 2017 Sep;9(9):1153-1155. doi: 10.2217/epi-2017-0077. Epub 2017 Aug 11. No abstract available.


A Novel Combination of Withaferin A and Sulforaphane Inhibits Epigenetic Machinery, Cellular Viability and Induces Apoptosis of Breast Cancer Cells.

Royston KJ, Udayakumar N, Lewis K, Tollefsbol TO.

Int J Mol Sci. 2017 May 19;18(5). pii: E1092. doi: 10.3390/ijms18051092.


Transforming Cancer Epigenetics Using Nutritive Approaches and Noncoding RNAs.

Dates CR, Tollefsbol TO.

Curr Cancer Drug Targets. 2018;18(1):32-38. doi: 10.2174/1568009617666170203165326.


Combinatorial epigenetic mechanisms and efficacy of early breast cancer inhibition by nutritive botanicals.

Li Y, Buckhaults P, Cui X, Tollefsbol TO.

Epigenomics. 2016 Aug;8(8):1019-37. doi: 10.2217/epi-2016-0024. Epub 2016 Aug 1.


Erratum to "Down-regulation of hTERT and Cyclin D1 transcription via PI3K/Akt and TGF-β pathways in MCF-7 cancer cells with PX-866 and Raloxifene" [Exp. Cell Res. 344 (2016) 95-102].

Peek GW, Tollefsbol TO.

Exp Cell Res. 2016 Jul 15;345(2):255. doi: 10.1016/j.yexcr.2016.05.021. Epub 2016 Jun 2. No abstract available.


Regulation of the Telomerase Reverse Transcriptase Subunit through Epigenetic Mechanisms.

Lewis KA, Tollefsbol TO.

Front Genet. 2016 May 9;7:83. doi: 10.3389/fgene.2016.00083. eCollection 2016. Review.


Down-regulation of hTERT and Cyclin D1 transcription via PI3K/Akt and TGF-β pathways in MCF-7 Cancer cells with PX-866 and Raloxifene.

Peek GW, Tollefsbol TO.

Exp Cell Res. 2016 May 15;344(1):95-102. doi: 10.1016/j.yexcr.2016.03.022. Epub 2016 Mar 23.


Epigenetic Regulation of Epidermal Stem Cell Biomarkers and Their Role in Wound Healing.

Saldanha SN, Royston KJ, Udayakumar N, Tollefsbol TO.

Int J Mol Sci. 2015 Dec 24;17(1). pii: E16. doi: 10.3390/ijms17010016. Review.


Combinatorial PX-866 and Raloxifene Decrease Rb Phosphorylation, Cyclin E2 Transcription, and Proliferation of MCF-7 Breast Cancer Cells.

Peek GW, Tollefsbol TO.

J Cell Biochem. 2016 Jul;117(7):1688-96. doi: 10.1002/jcb.25462. Epub 2015 Dec 28.


Influences of diet and the gut microbiome on epigenetic modulation in cancer and other diseases.

Paul B, Barnes S, Demark-Wahnefried W, Morrow C, Salvador C, Skibola C, Tollefsbol TO.

Clin Epigenetics. 2015 Oct 16;7:112. doi: 10.1186/s13148-015-0144-7. eCollection 2015. Review.


Impact of Nutrition on Non-Coding RNA Epigenetics in Breast and Gynecological Cancer.

Krakowsky RH, Tollefsbol TO.

Front Nutr. 2015 May 27;2:16. doi: 10.3389/fnut.2015.00016. eCollection 2015. Review.


Impact of Epigenetic Dietary Components on Cancer through Histone Modifications.

Gao Y, Tollefsbol TO.

Curr Med Chem. 2015;22(17):2051-64. Review.


The Epigenetic Impact of Cruciferous Vegetables on Cancer Prevention.

Royston KJ, Tollefsbol TO.

Curr Pharmacol Rep. 2015 Feb 1;1(1):46-51.


Epigenetic reactivation of p21CIP1/WAF1 and KLOTHO by a combination of bioactive dietary supplements is partially ERα-dependent in ERα-negative human breast cancer cells.

Sinha S, Shukla S, Khan S, Tollefsbol TO, Meeran SM.

Mol Cell Endocrinol. 2015 May 5;406:102-14. doi: 10.1016/j.mce.2015.02.020. Epub 2015 Feb 25.


Epigenetic linkage of aging, cancer and nutrition.

Daniel M, Tollefsbol TO.

J Exp Biol. 2015 Jan 1;218(Pt 1):59-70. doi: 10.1242/jeb.107110. Review.


Aging and energetics' 'Top 40' future research opportunities 2010-2013.

Allison DB, Antoine LH, Ballinger SW, Bamman MM, Biga P, Darley-Usmar VM, Fisher G, Gohlke JM, Halade GV, Hartman JL, Hunter GR, Messina JL, Nagy TR, Plaisance EP, Powell ML, Roth KA, Sandel MW, Schwartz TS, Smith DL, Sweatt JD, Tollefsbol TO, Watts SA, Yang Y, Zhang J, Austad SN.

F1000Res. 2014 Sep 12;3:219. doi: 10.12688/f1000research.5212.1. eCollection 2014. Review.


Molecular mechanisms for inhibition of colon cancer cells by combined epigenetic-modulating epigallocatechin gallate and sodium butyrate.

Saldanha SN, Kala R, Tollefsbol TO.

Exp Cell Res. 2014 May 15;324(1):40-53. doi: 10.1016/j.yexcr.2014.01.024. Epub 2014 Feb 8.


Dietary epigenetics in cancer and aging.

Tollefsbol TO.

Cancer Treat Res. 2014;159:257-67. doi: 10.1007/978-3-642-38007-5_15. Review.


Impact of epigenetic dietary compounds on transgenerational prevention of human diseases.

Li Y, Saldanha SN, Tollefsbol TO.

AAPS J. 2014 Jan;16(1):27-36. doi: 10.1208/s12248-013-9538-7. Epub 2013 Oct 11. Review.


Pathway modulations and epigenetic alterations in ovarian tumorbiogenesis.

Saldanha SN, Tollefsbol TO.

J Cell Physiol. 2014 Apr;229(4):393-406. doi: 10.1002/jcp.24466. Review.


Analysis of biomarkers of caloric restriction in aging cells.

Li Y, Tollefsbol TO.

Methods Mol Biol. 2013;1048:19-29. doi: 10.1007/978-1-62703-556-9_3.


Cell senescence culturing methods.

Chen H, Li Y, Tollefsbol TO.

Methods Mol Biol. 2013;1048:1-10. doi: 10.1007/978-1-62703-556-9_1.


Medicinal chemistry of the epigenetic diet and caloric restriction.

Martin SL, Hardy TM, Tollefsbol TO.

Curr Med Chem. 2013;20(32):4050-9. Review.


Real-time methylomic aberrations during initiation and progression of induced human mammary epithelial cell tumorigenesis.

Mitchell NE, Wilson ML, Bray MS, Crossman DK, Tollefsbol TO.

Epigenomics. 2013 Apr;5(2):155-65. doi: 10.2217/epi.13.6.


MicroRNAs: an emerging science in cancer epigenetics.

Kala R, Peek GW, Hardy TM, Tollefsbol TO.

J Clin Bioinforma. 2013 Mar 16;3(1):6. doi: 10.1186/2043-9113-3-6.


Epigenetic reactivation of estrogen receptor-α (ERα) by genistein enhances hormonal therapy sensitivity in ERα-negative breast cancer.

Li Y, Meeran SM, Patel SN, Chen H, Hardy TM, Tollefsbol TO.

Mol Cancer. 2013 Feb 4;12:9. doi: 10.1186/1476-4598-12-9.


Epigenetic regulation of multiple tumor-related genes leads to suppression of breast tumorigenesis by dietary genistein.

Li Y, Chen H, Hardy TM, Tollefsbol TO.

PLoS One. 2013;8(1):e54369. doi: 10.1371/journal.pone.0054369. Epub 2013 Jan 14.


Epigallocatechin gallate and sulforaphane combination treatment induce apoptosis in paclitaxel-resistant ovarian cancer cells through hTERT and Bcl-2 down-regulation.

Chen H, Landen CN, Li Y, Alvarez RD, Tollefsbol TO.

Exp Cell Res. 2013 Mar 10;319(5):697-706. doi: 10.1016/j.yexcr.2012.12.026. Epub 2013 Jan 16.


Insufficient DNA methylation affects healthy aging and promotes age-related health problems.

Liu L, van Groen T, Kadish I, Li Y, Wang D, James SR, Karpf AR, Tollefsbol TO.

Clin Epigenetics. 2011 Aug;2(2):349-60. doi: 10.1007/s13148-011-0042-6. Epub 2011 Jun 12.


The transposon-driven evolutionary origin and basis of histone deacetylase functions and limitations in disease prevention.

Peek GW, Tollefsbol TO.

Clin Epigenetics. 2011 Aug;2(2):97-112. doi: 10.1007/s13148-011-0020-z. Epub 2011 Jan 26.


Bioactive dietary supplements reactivate ER expression in ER-negative breast cancer cells by active chromatin modifications.

Meeran SM, Patel SN, Li Y, Shukla S, Tollefsbol TO.

PLoS One. 2012;7(5):e37748. doi: 10.1371/journal.pone.0037748. Epub 2012 May 25.


Mitochondrial regulation of epigenetics and its role in human diseases.

Minocherhomji S, Tollefsbol TO, Singh KK.

Epigenetics. 2012 Apr;7(4):326-34. doi: 10.4161/epi.19547. Epub 2012 Apr 1. Review.


Regulation of the human catalytic subunit of telomerase (hTERT).

Daniel M, Peek GW, Tollefsbol TO.

Gene. 2012 May 1;498(2):135-46. doi: 10.1016/j.gene.2012.01.095. Epub 2012 Feb 13. Review.


Epigenomics of ovarian cancer and its chemoprevention.

Chen H, Hardy TM, Tollefsbol TO.

Front Genet. 2011 Oct 4;2:67. doi: 10.3389/fgene.2011.00067. eCollection 2011.


The role of nutraceuticals in chemoprevention and chemotherapy and their clinical outcomes.

Saldanha SN, Tollefsbol TO.

J Oncol. 2012;2012:192464. doi: 10.1155/2012/192464. Epub 2011 Dec 7.


Epigenetic diet: impact on the epigenome and cancer.

Hardy TM, Tollefsbol TO.

Epigenomics. 2011 Aug;3(4):503-18. doi: 10.2217/epi.11.71. Review.

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