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Items: 32

1.

Transcriptional synergy as an emergent property defining cell subpopulation identity enables population shift.

Okawa S, Saltó C, Ravichandran S, Yang S, Toledo EM, Arenas E, Del Sol A.

Nat Commun. 2018 Jul 3;9(1):2595. doi: 10.1038/s41467-018-05016-8.

2.

Niche-derived laminin-511 promotes midbrain dopaminergic neuron survival and differentiation through YAP.

Zhang D, Yang S, Toledo EM, Gyllborg D, Saltó C, Carlos Villaescusa J, Arenas E.

Sci Signal. 2017 Aug 22;10(493). pii: eaal4165. doi: 10.1126/scisignal.aal4165.

PMID:
28831020
3.

Retraction Notice to: Vulnerability of Glioblastoma Cells to Catastrophic Vacuolization and Death Induced by a Small Molecule.

Kitambi SS, Toledo EM, Usoskin D, Wee S, Harisankar A, Svensson R, Sigmundsson K, Kalderén C, Niklasson M, Kundu S, Aranda S, Westermark B, Uhrbom L, Andäng M, Damberg P, Nelander S, Arenas E, Artursson P, Walfridsson J, Nilsson KF, Hammarström LGJ, Ernfors P.

Cell. 2017 Jul 13;170(2):407. doi: 10.1016/j.cell.2017.06.044. No abstract available.

4.

Translation of WNT developmental programs into stem cell replacement strategies for the treatment of Parkinson's disease.

Toledo EM, Gyllborg D, Arenas E.

Br J Pharmacol. 2017 Dec;174(24):4716-4724. doi: 10.1111/bph.13871. Epub 2017 Jul 9. Review.

PMID:
28547771
5.

Mapping genes for calcium signaling and their associated human genetic disorders.

Hörtenhuber M, Toledo EM, Smedler E, Arenas E, Malmersjö S, Louhivuori L, Uhlén P.

Bioinformatics. 2017 Aug 15;33(16):2547-2554. doi: 10.1093/bioinformatics/btx225.

6.

Induction of functional dopamine neurons from human astrocytes in vitro and mouse astrocytes in a Parkinson's disease model.

Rivetti di Val Cervo P, Romanov RA, Spigolon G, Masini D, Martín-Montañez E, Toledo EM, La Manno G, Feyder M, Pifl C, Ng YH, Sánchez SP, Linnarsson S, Wernig M, Harkany T, Fisone G, Arenas E.

Nat Biotechnol. 2017 May;35(5):444-452. doi: 10.1038/nbt.3835. Epub 2017 Apr 10.

PMID:
28398344
7.

Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells.

La Manno G, Gyllborg D, Codeluppi S, Nishimura K, Salto C, Zeisel A, Borm LE, Stott SRW, Toledo EM, Villaescusa JC, Lönnerberg P, Ryge J, Barker RA, Arenas E, Linnarsson S.

Cell. 2016 Oct 6;167(2):566-580.e19. doi: 10.1016/j.cell.2016.09.027.

8.

A PBX1 transcriptional network controls dopaminergic neuron development and is impaired in Parkinson's disease.

Villaescusa JC, Li B, Toledo EM, Rivetti di Val Cervo P, Yang S, Stott SR, Kaiser K, Islam S, Gyllborg D, Laguna-Goya R, Landreh M, Lönnerberg P, Falk A, Bergman T, Barker RA, Linnarsson S, Selleri L, Arenas E.

EMBO J. 2016 Sep 15;35(18):1963-78. doi: 10.15252/embj.201593725. Epub 2016 Jun 28.

9.

An electromechanical left ventricular wedge model to study the effects of deformation on repolarization during heart failure.

Rocha BM, Toledo EM, Barra LP, dos Santos RW.

Biomed Res Int. 2015;2015:465014. doi: 10.1155/2015/465014. Epub 2015 Oct 15.

10.

Anti-ribosomal P protein autoantibodies from patients with neuropsychiatric lupus impair memory in mice.

Bravo-Zehnder M, Toledo EM, Segovia-Miranda F, Serrano FG, Benito MJ, Metz C, Retamal C, Álvarez A, Massardo L, Inestrosa NC, González A.

Arthritis Rheumatol. 2015 Jan;67(1):204-14. doi: 10.1002/art.38900.

11.

RETRACTED: Vulnerability of glioblastoma cells to catastrophic vacuolization and death induced by a small molecule.

Kitambi SS, Toledo EM, Usoskin D, Wee S, Harisankar A, Svensson R, Sigmundsson K, Kalderén C, Niklasson M, Kundu S, Aranda S, Westermark B, Uhrbom L, Andäng M, Damberg P, Nelander S, Arenas E, Artursson P, Walfridsson J, Forsberg Nilsson K, Hammarström LGJ, Ernfors P.

Cell. 2014 Apr 10;157(2):313-328. doi: 10.1016/j.cell.2014.02.021. Epub 2014 Mar 20. Retraction in: Cell. 2017 Jul 13;170(2):407.

12.

Effects of deformation on transmural dispersion of repolarization using in silico models of human left ventricular wedge.

de Oliveira BL, Rocha BM, Barra LP, Toledo EM, Sundnes J, Weber dos Santos R.

Int J Numer Method Biomed Eng. 2013 Dec;29(12):1323-37. doi: 10.1002/cnm.2570. Epub 2013 Jun 23.

PMID:
23794390
13.

Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis.

Theofilopoulos S, Wang Y, Kitambi SS, Sacchetti P, Sousa KM, Bodin K, Kirk J, Saltó C, Gustafsson M, Toledo EM, Karu K, Gustafsson JÅ, Steffensen KR, Ernfors P, Sjövall J, Griffiths WJ, Arenas E.

Nat Chem Biol. 2013 Feb;9(2):126-33. doi: 10.1038/nchembio.1156. Epub 2012 Dec 23.

PMID:
23292650
14.

Peroxisome proliferators reduce spatial memory impairment, synaptic failure, and neurodegeneration in brains of a double transgenic mice model of Alzheimer's disease.

Inestrosa NC, Carvajal FJ, Zolezzi JM, Tapia-Rojas C, Serrano F, Karmelic D, Toledo EM, Toro A, Toro J, Santos MJ.

J Alzheimers Dis. 2013;33(4):941-59. doi: 10.3233/JAD-2012-120397.

PMID:
23109558
15.

SFRP1 and SFRP2 dose-dependently regulate midbrain dopamine neuron development in vivo and in embryonic stem cells.

Kele J, Andersson ER, Villaescusa JC, Cajanek L, Parish CL, Bonilla S, Toledo EM, Bryja V, Rubin JS, Shimono A, Arenas E.

Stem Cells. 2012 May;30(5):865-75. doi: 10.1002/stem.1049.

16.

The role of Wnt signaling in neuroprotection.

Cerpa W, Toledo EM, Varela-Nallar L, Inestrosa NC.

Drug News Perspect. 2009 Dec;22(10):579-91. doi: 10.1358/dnp.2009.10.1436817. Review.

PMID:
20140278
17.

Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway.

Arrázola MS, Varela-Nallar L, Colombres M, Toledo EM, Cruzat F, Pavez L, Assar R, Aravena A, González M, Montecino M, Maass A, Martínez S, Inestrosa NC.

J Cell Physiol. 2009 Dec;221(3):658-67. doi: 10.1002/jcp.21902.

PMID:
19711354
18.

c-Abl tyrosine kinase modulates tau pathology and Cdk5 phosphorylation in AD transgenic mice.

Cancino GI, Perez de Arce K, Castro PU, Toledo EM, von Bernhardi R, Alvarez AR.

Neurobiol Aging. 2011 Jul;32(7):1249-61. doi: 10.1016/j.neurobiolaging.2009.07.007. Epub 2009 Aug 22.

PMID:
19700222
19.
20.

Finite element stress analysis of dental prostheses supported by straight and angled implants.

Cruz M, Wassall T, Toledo EM, da Silva Barra LP, Cruz S.

Int J Oral Maxillofac Implants. 2009 May-Jun;24(3):391-403.

PMID:
19587860
21.

Wnt signaling in neuroprotection and stem cell differentiation.

Toledo EM, Colombres M, Inestrosa NC.

Prog Neurobiol. 2008 Nov;86(3):281-96. doi: 10.1016/j.pneurobio.2008.08.001. Epub 2008 Aug 19. Review.

PMID:
18786602
22.

The role of Wnt signaling in neuronal dysfunction in Alzheimer's Disease.

Inestrosa NC, Toledo EM.

Mol Neurodegener. 2008 Jul 24;3:9. doi: 10.1186/1750-1326-3-9.

23.

STI571 prevents apoptosis, tau phosphorylation and behavioural impairments induced by Alzheimer's beta-amyloid deposits.

Cancino GI, Toledo EM, Leal NR, Hernandez DE, Yévenes LF, Inestrosa NC, Alvarez AR.

Brain. 2008 Sep;131(Pt 9):2425-42. doi: 10.1093/brain/awn125. Epub 2008 Jun 17.

PMID:
18559370
24.

Comparative 3D finite element stress analysis of straight and angled wedge-shaped implant designs.

Las Casas EB, Ferreira PC, Cimini CA Jr, Toledo EM, Barra LP, Cruz M.

Int J Oral Maxillofac Implants. 2008 Mar-Apr;23(2):215-25.

PMID:
18548917
25.

Wnt-7a induces presynaptic colocalization of alpha 7-nicotinic acetylcholine receptors and adenomatous polyposis coli in hippocampal neurons.

Farías GG, Vallés AS, Colombres M, Godoy JA, Toledo EM, Lukas RJ, Barrantes FJ, Inestrosa NC.

J Neurosci. 2007 May 16;27(20):5313-25.

26.

Finite element stress analysis of cuneiform and cylindrical threaded implant geometries.

Cruz M, Lourenço AF, Toledo EM, da Silva Barra LP, de Castro Lemonge AC, Wassall T.

Technol Health Care. 2006;14(4-5):421-38. Review.

PMID:
17065763
27.

The functional links between prion protein and copper.

Varela-Nallar L, Toledo EM, Chacón MA, Inestrosa NC.

Biol Res. 2006;39(1):39-44. Review.

28.

Induction of cellular prion protein gene expression by copper in neurons.

Varela-Nallar L, Toledo EM, Larrondo LF, Cabral AL, Martins VR, Inestrosa NC.

Am J Physiol Cell Physiol. 2006 Jan;290(1):C271-81. Epub 2005 Sep 7.

29.

Three-dimensional finite element stress analysis of a cuneiform-geometry implant.

Cruz M, Wassall T, Toledo EM, Barra LP, Lemonge AC.

Int J Oral Maxillofac Implants. 2003 Sep-Oct;18(5):675-84.

PMID:
14579955
30.

Anthropology and style of life in middle age women.

Prado Martinez C, Diaz ME, Toledo EM, Carmenate MM, Wong I, Moreno R, Moreno V.

Coll Antropol. 2003 Jun;27(1):151-9.

PMID:
12974142
31.

Fat distribution in Cuban infants.

Diaz ME, Montero M, Wong I, Moreno V, Toledo EM, Moreno R.

Am J Hum Biol. 1994;6(6):687-692. doi: 10.1002/ajhb.1310060602.

PMID:
28548325
32.

[Intervertebral disk herniation in adolescence].

KUZARY JZ, TOLEDO EM.

Harefuah. 1962 Nov 1;63:328-30. Hebrew. No abstract available.

PMID:
13927688

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