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Items: 1 to 50 of 94

1.

Current status and limitations of immunotherapy for breast cancer.

Tokumaru Y, Joyce D, Takabe K.

Surgery. 2020 Mar;167(3):628-630. doi: 10.1016/j.surg.2019.09.018. Epub 2019 Oct 14. No abstract available.

PMID:
31623855
2.

Combination chemotherapy with TAS-102 plus bevacizumab in salvage-line treatment of metastatic colorectal cancer: A single-center, retrospective study examining the prognostic value of the modified Glasgow Prognostic Score in salvage-line therapy of metastatic colorectal cancer.

Matsuhashi N, Takahashi T, Fujii H, Suetsugu T, Fukada M, Iwata Y, Tokumaru Y, Imai T, Mori R, Tanahashi T, Matsui S, Imai H, Tanaka Y, Yamaguchi K, Futamura M, Yoshida K.

Mol Clin Oncol. 2019 Oct;11(4):390-396. doi: 10.3892/mco.2019.1899. Epub 2019 Jul 18.

3.

MicroRNA-143/Musashi-2/KRAS cascade contributes positively to carcinogenesis in human bladder cancer.

Tsujino T, Sugito N, Taniguchi K, Honda R, Komura K, Yoshikawa Y, Takai T, Minami K, Kuranaga Y, Shinohara H, Tokumaru Y, Heishima K, Inamoto T, Azuma H, Akao Y.

Cancer Sci. 2019 Jul;110(7):2189-2199. doi: 10.1111/cas.14035. Epub 2019 May 27.

4.

Efficacy of combination therapy with zoledronic acid and cetuximab for unresectable rectal cancer with bone metastases: A case report.

Tokumaru Y, Matsuhashi N, Takahashi T, Tanahashi T, Matsui S, Imai H, Tanaka Y, Yamaguchi K, Yoshida K.

Mol Clin Oncol. 2019 Jun;10(6):571-574. doi: 10.3892/mco.2019.1836. Epub 2019 Apr 3.

5.

Synthetic miR-143 Inhibits Growth of HER2-Positive Gastric Cancer Cells by Suppressing KRAS Networks Including DDX6 RNA Helicase.

Tokumaru Y, Tajirika T, Sugito N, Kuranaga Y, Shinohara H, Tsujino T, Matsuhashi N, Futamura M, Akao Y, Yoshida K.

Int J Mol Sci. 2019 Apr 5;20(7). pii: E1697. doi: 10.3390/ijms20071697.

6.

Targeted proteome analysis of microalgae under high-light conditions by optimized protein extraction of photosynthetic organisms.

Toyoshima M, Sakata M, Ohnishi K, Tokumaru Y, Kato Y, Tokutsu R, Sakamoto W, Minagawa J, Matsuda F, Shimizu H.

J Biosci Bioeng. 2019 Mar;127(3):394-402. doi: 10.1016/j.jbiosc.2018.09.001. Epub 2018 Sep 28.

PMID:
30274798
7.

The mode of progressive disease affects the prognosis of patients with metastatic breast cancer.

Mori R, Futamura M, Morimitsu K, Asano Y, Tokumaru Y, Kitazawa M, Yoshida K.

World J Surg Oncol. 2018 Aug 14;16(1):169. doi: 10.1186/s12957-018-1472-9.

8.

DEAD-Box Protein RNA-Helicase DDX6 Regulates the Expression of HER2 and FGFR2 at the Post-Transcriptional Step in Gastric Cancer Cells.

Tajirika T, Tokumaru Y, Taniguchi K, Sugito N, Matsuhashi N, Futamura M, Yanagihara K, Akao Y, Yoshida K.

Int J Mol Sci. 2018 Jul 9;19(7). pii: E2005. doi: 10.3390/ijms19072005.

9.

Comparative Targeted Proteomics of the Central Metabolism and Photosystems in SigE Mutant Strains of Synechocystis sp. PCC 6803.

Tokumaru Y, Uebayashi K, Toyoshima M, Osanai T, Matsuda F, Shimizu H.

Molecules. 2018 May 1;23(5). pii: E1051. doi: 10.3390/molecules23051051.

10.

Identification of highly selective and potent orexin receptor 1 antagonists derived from a dual orexin receptor 1/2 antagonist based on the structural framework of pyrazoylethylbenzamide.

Futamura A, Nozawa D, Araki Y, Tamura Y, Tokura S, Kawamoto H, Tokumaru Y, Kakihara S, Aoki T, Ohtake N.

Bioorg Med Chem. 2017 Oct 15;25(20):5203-5215. doi: 10.1016/j.bmc.2017.07.051. Epub 2017 Jul 29.

PMID:
28807572
11.

Independent exercise for glottal incompetence to improve vocal problems and prevent aspiration pneumonia in the elderly: a randomized controlled trial.

Fujimaki Y, Tsunoda K, Kobayashi R, Tonghyo C, Tanaka F, Kuroda H, Numata T, Ishii T, Kuroda R, Masuda S, Hashimoto S, Misawa H, Shindo N, Mori T, Mori H, Uchiyama N, Kamei Y, Tanaka M, Hamaya H, Funatsuki S, Usui S, Ito I, Hamada K, Shindo A, Tokumaru Y, Morita Y, Ueha R, Nito T, Kikuta S, Sekimoto S, Kondo K, Sakamoto T, Itoh K, Yamasoba T, Matsumoto S; Research Group for Aspiration Pneumonia, National Hospital Organization, Japan.

Clin Rehabil. 2017 Aug;31(8):1049-1056. doi: 10.1177/0269215516673208. Epub 2016 Oct 14.

12.

Alanine-fortified tomatoes relieve the acute alcohol-induced adverse effects in healthy men: a randomized cross-over study.

Oshima S, Shiiya S, Tokumaru Y, Kanda T.

Nutr Metab (Lond). 2016 Apr 5;13:25. doi: 10.1186/s12986-016-0087-9. eCollection 2016.

13.

Alanine with the Precipitate of Tomato Juice Administered to Rats Enhances the Reduction in Blood Ethanol Levels.

Oshima S, Shiiya S, Tokumaru Y, Kanda T.

J Nutr Metab. 2015;2015:280781. doi: 10.1155/2015/280781. Epub 2015 Dec 2.

14.

Expression of Oct3/4 and Nanog in the head and neck squamous carcinoma cells and its clinical implications for delayed neck metastasis in stage I/II oral tongue squamous cell carcinoma.

Habu N, Imanishi Y, Kameyama K, Shimoda M, Tokumaru Y, Sakamoto K, Fujii R, Shigetomi S, Otsuka K, Sato Y, Watanabe Y, Ozawa H, Tomita T, Fujii M, Ogawa K.

BMC Cancer. 2015 Oct 19;15:730. doi: 10.1186/s12885-015-1732-9.

15.

Prevalence of human papillomavirus in oropharyngeal cancer: a multicenter study in Japan.

Hama T, Tokumaru Y, Fujii M, Yane K, Okami K, Kato K, Masuda M, Mineta H, Nakashima T, Sugasawa M, Sakihama N, Yoshizaki T, Hanazawa T, Kato H, Hirano S, Imanishi Y, Kuratomi Y, Otsuki N, Ota I, Sugimoto T, Suzuki S.

Oncology. 2014;87(3):173-82. doi: 10.1159/000360991. Epub 2014 Jul 12.

PMID:
25033838
16.

Large cell neuroendocrine carcinoma of the submandibular gland: case report and literature review.

Yamamoto N, Minami S, Kidoguchi M, Shindo A, Tokumaru Y, Fujii M.

Auris Nasus Larynx. 2014 Feb;41(1):105-8. doi: 10.1016/j.anl.2013.07.010. Epub 2013 Aug 13. Review.

PMID:
23953500
17.

Present and Future of EGFR Inhibitors for Head and Neck Squamous Cell Cancer.

Baba Y, Fujii M, Tokumaru Y, Kato Y.

J Oncol. 2012;2012:986725. doi: 10.1155/2012/986725. Epub 2012 Mar 26.

18.

Preoperative embolization of the common hepatic artery for radical surgery of extrahepatic cholangiocarcinoma.

Sasaki Y, Osada S, Kondo H, Goshima S, Tokumaru Y, Yasufuku I, Kanematsu M, Yoshida K.

Am Surg. 2011 Dec;77(12):E269-71. No abstract available.

PMID:
22273192
19.

Common but critical sensation in older adults.

Suto Y, Tsunoda K, Chong T, Morita Y, Nakamura Y, Isobe Y, Tokumaru Y, Bito S.

J Am Geriatr Soc. 2011 Oct;59(10):1963-4. doi: 10.1111/j.1532-5415.2011.03610_2.x. No abstract available.

PMID:
22091510
20.

Characterization of lateral flagella of Selenomonas ruminantium.

Haya S, Tokumaru Y, Abe N, Kaneko J, Aizawa S.

Appl Environ Microbiol. 2011 Apr;77(8):2799-802. doi: 10.1128/AEM.00286-11. Epub 2011 Feb 18.

21.

[Hyponatremia with cisplatin administration in head and neck cancer patients].

Yajima Y, Fujii M, Tokumaru Y, Habu N.

Gan To Kagaku Ryoho. 2010 Dec;37(13):2861-5. Japanese.

PMID:
21160261
22.

Identification of stem-like cells in head and neck cancer cell lines.

Sun G, Fujii M, Sonoda A, Tokumaru Y, Matsunaga T, Habu N.

Anticancer Res. 2010 Jun;30(6):2005-10.

PMID:
20651344
23.

Flexion-induced cervical myelopathy associated with fewer elastic fibers and thickening in the posterior dura mater.

Yoshiyama Y, Tokumaru Y, Arai K.

J Neurol. 2010 Jan;257(1):149-51. doi: 10.1007/s00415-009-5329-6.

PMID:
19960201
24.

Promoted cell proliferation by connexin 30 gene transfection to head-and-neck cancer cell line.

Ozawa H, Mutai H, Matsunaga T, Tokumaru Y, Fujii M, Sakamoto K, Tomita T, Ogawa K.

Anticancer Res. 2009 Jun;29(6):1981-5.

25.

The role of PGP9.5 as a tumor suppressor gene in human cancer.

Tokumaru Y, Yamashita K, Kim MS, Park HL, Osada M, Mori M, Sidransky D.

Int J Cancer. 2008 Aug 15;123(4):753-9. doi: 10.1002/ijc.23354.

26.

HOP/OB1/NECC1 promoter DNA is frequently hypermethylated and involved in tumorigenic ability in esophageal squamous cell carcinoma.

Yamashita K, Kim MS, Park HL, Tokumaru Y, Osada M, Inoue H, Mori M, Sidransky D.

Mol Cancer Res. 2008 Jan;6(1):31-41. doi: 10.1158/1541-7786.MCR-07-0213.

27.

Evaluation of promoter hypermethylation detection in body fluids as a screening/diagnosis tool for head and neck squamous cell carcinoma.

Carvalho AL, Jeronimo C, Kim MM, Henrique R, Zhang Z, Hoque MO, Chang S, Brait M, Nayak CS, Jiang WW, Claybourne Q, Tokumaru Y, Lee J, Goldenberg D, Garrett-Mayer E, Goodman S, Moon CS, Koch W, Westra WH, Sidransky D, Califano JA.

Clin Cancer Res. 2008 Jan 1;14(1):97-107. doi: 10.1158/1078-0432.CCR-07-0722.

28.

A promoter methylation pattern in the N-methyl-D-aspartate receptor 2B gene predicts poor prognosis in esophageal squamous cell carcinoma.

Kim MS, Yamashita K, Chae YK, Tokumaru Y, Chang X, Zahurak M, Osada M, Park HL, Chuang A, Califano JA, Sidransky D.

Clin Cancer Res. 2007 Nov 15;13(22 Pt 1):6658-65.

29.

Appropriate diameter for screws to fix the maxilla following Le Fort I osteotomy: an investigation utilizing finite element analysis.

Nagasao T, Miyamoto J, Hikosaka M, Nagasao M, Tokumaru Y, Ogawa K, Nakajima T.

J Craniomaxillofac Surg. 2007 Jun-Jul;35(4-5):227-33. Epub 2007 Sep 12.

PMID:
17855106
30.

Decreased expression of connexin-30 and aberrant expression of connexin-26 in human head and neck cancer.

Ozawa H, Matsunaga T, Kamiya K, Tokumaru Y, Fujii M, Tomita T, Ogawa K.

Anticancer Res. 2007 Jul-Aug;27(4B):2189-95.

31.

PGP9.5 methylation in diffuse-type gastric cancer.

Yamashita K, Park HL, Kim MS, Osada M, Tokumaru Y, Inoue H, Mori M, Sidransky D.

Cancer Res. 2006 Apr 1;66(7):3921-7.

32.

Nationwide survey of juvenile muscular atrophy of distal upper extremity (Hirayama disease) in Japan.

Tashiro K, Kikuchi S, Itoyama Y, Tokumaru Y, Sobue G, Mukai E, Akiguchi I, Nakashima K, Kira J, Hirayama K.

Amyotroph Lateral Scler. 2006 Mar;7(1):38-45.

PMID:
16546758
33.

[Aberrant promoter hypermethylation of tazarotine-induced gene 1 (TIG1) in head and neck cancer].

Tokumaru Y, Yahata Y, Fujii M.

Nihon Jibiinkoka Gakkai Kaiho. 2005 Dec;108(12):1152-7. Japanese.

PMID:
16440812
34.

PGP9.5 promoter methylation is an independent prognostic factor for esophageal squamous cell carcinoma.

Mandelker DL, Yamashita K, Tokumaru Y, Mimori K, Howard DL, Tanaka Y, Carvalho AL, Jiang WW, Park HL, Kim MS, Osada M, Mori M, Sidransky D.

Cancer Res. 2005 Jun 1;65(11):4963-8.

35.

HyperIgEaemia in patients with juvenile muscular atrophy of the distal upper extremity (Hirayama disease).

Ito S, Kuwabara S, Fukutake T, Tokumaru Y, Hattori T.

J Neurol Neurosurg Psychiatry. 2005 Jan;76(1):132-4.

36.

Comparative evaluation of the Desoxycholate Agar Nissui Food Stamp and swab methods for estimating coliform organisms in poultry processing plants after cleaning in Japan.

Kodaka H, Goto K, Umeki K, Nishina T, Tokumaru Y, Shinagawa K, Konuma H.

J Basic Microbiol. 2004;44(6):445-50.

PMID:
15558825
37.

Inverse correlation between cyclin A1 hypermethylation and p53 mutation in head and neck cancer identified by reversal of epigenetic silencing.

Tokumaru Y, Yamashita K, Osada M, Nomoto S, Sun DI, Xiao Y, Hoque MO, Westra WH, Califano JA, Sidransky D.

Cancer Res. 2004 Sep 1;64(17):5982-7.

38.

Optimal use of a panel of methylation markers with GSTP1 hypermethylation in the diagnosis of prostate adenocarcinoma.

Tokumaru Y, Harden SV, Sun DI, Yamashita K, Epstein JI, Sidransky D.

Clin Cancer Res. 2004 Aug 15;10(16):5518-22.

39.

Quantitative GSTP1 methylation levels correlate with Gleason grade and tumor volume in prostate needle biopsies.

Zhou M, Tokumaru Y, Sidransky D, Epstein JI.

J Urol. 2004 Jun;171(6 Pt 1):2195-8.

PMID:
15126784
40.

Detection of promoter hypermethylation of multiple genes in the tumor and bronchoalveolar lavage of patients with lung cancer.

Topaloglu O, Hoque MO, Tokumaru Y, Lee J, Ratovitski E, Sidransky D, Moon CS.

Clin Cancer Res. 2004 Apr 1;10(7):2284-8.

41.

Biallelic inactivation of the RIZ1 gene in human gastric cancer.

Tokumaru Y, Nomoto S, Jerónimo C, Henrique R, Harden S, Trink B, Sidransky D.

Oncogene. 2003 Oct 9;22(44):6954-8.

PMID:
14534544
42.

The inhibitory effect of matrix metalloproteinase inhibitor ONO-4817 on lymph node metastasis in tongue carcinoma.

Yamashita T, Fujii M, Tomita T, Ishiguro R, Tashiro M, Tokumaru Y, Imanishi Y, Kanke M, Ogawa K, Kameyama K, Otani Y.

Anticancer Res. 2003 May-Jun;23(3B):2297-302.

PMID:
12894506
43.

Re: Is TIG1 a new tumor suppressor in prostate cancer?

Tokumaru Y, Sun DI, Nomoto S, Yamashita K, Sidransky D.

J Natl Cancer Inst. 2003 Jun 18;95(12):919-20. No abstract available.

PMID:
12813179
44.

Methylation of the thyroid-stimulating hormone receptor gene in epithelial thyroid tumors: a marker of malignancy and a cause of gene silencing.

Xing M, Usadel H, Cohen Y, Tokumaru Y, Guo Z, Westra WB, Tong BC, Tallini G, Udelsman R, Califano JA, Ladenson PW, Sidransky D.

Cancer Res. 2003 May 1;63(9):2316-21.

45.

Hypermethylation of the Pendred syndrome gene SLC26A4 is an early event in thyroid tumorigenesis.

Xing M, Tokumaru Y, Wu G, Westra WB, Ladenson PW, Sidransky D.

Cancer Res. 2003 May 1;63(9):2312-5.

46.

Gene promoter hypermethylation in tumors and lymph nodes of stage I lung cancer patients.

Harden SV, Tokumaru Y, Westra WH, Goodman S, Ahrendt SA, Yang SC, Sidransky D.

Clin Cancer Res. 2003 Apr;9(4):1370-5.

47.

[Statistical analysis of maxillary sinus squamous cell carcinoma].

Yamashita T, Fujii M, Ishiguro R, Tashiro M, Ohno Y, Tokumaru Y, Kanke M, Imanishi Y, Tomita T, Kanzaki J, Inuyama Y.

Nihon Jibiinkoka Gakkai Kaiho. 2002 Jun;105(6):732-40. Japanese.

PMID:
12138701
48.

Production and immunogenic efficacy of botulinum tetravalent (A, B, E, F) toxoid.

Torii Y, Tokumaru Y, Kawaguchi S, Izumi N, Maruyama S, Mukamoto M, Kozaki S, Takahashi M.

Vaccine. 2002 Jun 7;20(19-20):2556-61.

PMID:
12057613
49.

[Cervical collar therapy for juvenile muscular atrophy of distal upper extremity (Hirayama disease): results from 38 cases].

Tokumaru Y, Hirayama K.

Rinsho Shinkeigaku. 2001 Apr-May;41(4-5):173-8. Japanese.

PMID:
11676157
50.

Manifest Anxiety Scale for evaluation of effects of granisetron in chemotherapy with CDDP and 5FU for head and neck cancer.

Fujii M, Ohno Y, Tokumaru Y, Imanishi Y, Kanke M, Tomita T, Kanzaki J.

Support Care Cancer. 2001 Jul;9(5):366-71.

PMID:
11497391

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