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Items: 47

1.

Glycolysis regulated transglutaminase 2 activation in cardiopulmonary fibrogenic remodeling.

Bhedi CD, Nasirova S, Toksoz D, Warburton RR, Morine KJ, Kapur NK, Galper JB, Preston IR, Hill NS, Fanburg BL, Penumatsa KC.

FASEB J. 2020 Jan;34(1):930-944. doi: 10.1096/fj.201902155R. Epub 2019 Nov 28.

PMID:
31914588
2.

Unraveling endothelin-1 induced hypercontractility of human pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension.

Wilson JL, Warburton R, Taylor L, Toksoz D, Hill N, Polgar P.

PLoS One. 2018 Apr 12;13(4):e0195780. doi: 10.1371/journal.pone.0195780. eCollection 2018.

3.

Transglutaminase 2 in pulmonary and cardiac tissue remodeling in experimental pulmonary hypertension.

Penumatsa KC, Toksoz D, Warburton RR, Kharnaf M, Preston IR, Kapur NK, Khosla C, Hill NS, Fanburg BL.

Am J Physiol Lung Cell Mol Physiol. 2017 Nov 1;313(5):L752-L762. doi: 10.1152/ajplung.00170.2017. Epub 2017 Aug 3.

4.

Plasma 12- and 15-hydroxyeicosanoids are predictors of survival in pulmonary arterial hypertension.

Al-Naamani N, Sagliani KD, Dolnikowski GG, Warburton RR, Toksoz D, Kayyali U, Hill NS, Fanburg BL, Roberts KE, Preston IR.

Pulm Circ. 2016 Jun;6(2):224-33. doi: 10.1086/686311.

5.

Alpha-Catulin Co-Localizes With Vimentin Intermediate Filaments and Functions in Pulmonary Vascular Endothelial Cell Migration via ROCK.

Bear MD, Liu T, Abualkhair S, Ghamloush MA, Hill NS, Preston I, Fanburg BL, Kayyali US, Toksoz D.

J Cell Physiol. 2016 Apr;231(4):934-43. doi: 10.1002/jcp.25185. Epub 2015 Sep 17.

PMID:
26377600
6.

Tissue transglutaminase promotes serotonin-induced AKT signaling and mitogenesis in pulmonary vascular smooth muscle cells.

Penumatsa K, Abualkhair S, Wei L, Warburton R, Preston I, Hill NS, Watts SW, Fanburg BL, Toksoz D.

Cell Signal. 2014 Dec;26(12):2818-25. doi: 10.1016/j.cellsig.2014.09.002. Epub 2014 Sep 15.

7.

Role of hypoxia-induced transglutaminase 2 in pulmonary artery smooth muscle cell proliferation.

Penumatsa KC, Toksoz D, Warburton RR, Hilmer AJ, Liu T, Khosla C, Comhair SA, Fanburg BL.

Am J Physiol Lung Cell Mol Physiol. 2014 Oct 1;307(7):L576-85. doi: 10.1152/ajplung.00162.2014. Epub 2014 Aug 15.

8.

Modulating endothelial barrier function by targeting vimentin phosphorylation.

Liu T, Ghamloush MM, Aldawood A, Warburton R, Toksoz D, Hill NS, Tang DD, Kayyali US.

J Cell Physiol. 2014 Oct;229(10):1484-93. doi: 10.1002/jcp.24590.

PMID:
24648251
9.

Elevated transglutaminase 2 activity is associated with hypoxia-induced experimental pulmonary hypertension in mice.

DiRaimondo TR, Klöck C, Warburton R, Herrera Z, Penumatsa K, Toksoz D, Hill N, Khosla C, Fanburg B.

ACS Chem Biol. 2014 Jan 17;9(1):266-75. doi: 10.1021/cb4006408. Epub 2013 Nov 5.

10.

The Lbc Rho guanine nucleotide exchange factor α-catulin axis functions in serotonin-induced vascular smooth muscle cell mitogenesis and RhoA/ROCK activation.

Bear MD, Li M, Liu Y, Giel-Moloney MA, Fanburg BL, Toksoz D.

J Biol Chem. 2010 Oct 22;285(43):32919-26. doi: 10.1074/jbc.M109.062513. Epub 2010 Aug 9.

11.

Serotonin induces Rho/ROCK-dependent activation of Smads 1/5/8 in pulmonary artery smooth muscle cells.

Liu Y, Ren W, Warburton R, Toksoz D, Fanburg BL.

FASEB J. 2009 Jul;23(7):2299-306. doi: 10.1096/fj.08-127910. Epub 2009 Feb 25.

PMID:
19244313
12.

Alpha(E)-Catenin induces SRF-dependent transcriptional activity through its C-terminal region and is partly RhoA/ROCK-dependent.

Merdek KD, Jaffe AB, Dutt P, Olson MF, Hall A, Fanburg BL, Kayyali US, Toksoz D.

Biochem Biophys Res Commun. 2008 Feb 15;366(3):717-23. Epub 2007 Dec 17.

13.
14.

Inhibition of serotonin-induced mitogenesis, migration, and ERK MAPK nuclear translocation in vascular smooth muscle cells by atorvastatin.

Li M, Liu Y, Dutt P, Fanburg BL, Toksoz D.

Am J Physiol Lung Cell Mol Physiol. 2007 Aug;293(2):L463-71. Epub 2007 Jun 1.

15.

Smooth muscle alpha-actin expression and myofibroblast differentiation by TGFbeta are dependent upon MK2.

Sousa AM, Liu T, Guevara O, Stevens J, Fanburg BL, Gaestel M, Toksoz D, Kayyali US.

J Cell Biochem. 2007 Apr 15;100(6):1581-92.

16.

Cell proliferation and drug resistance in hepatocellular carcinoma are modulated by Rho GTPase signals.

Sterpetti P, Marucci L, Candelaresi C, Toksoz D, Alpini G, Ugili L, Baroni GS, Macarri G, Benedetti A.

Am J Physiol Gastrointest Liver Physiol. 2006 Apr;290(4):G624-32. Epub 2005 Dec 1.

17.

Galphaz inhibits serum response factor-dependent transcription by inhibiting Rho signaling.

Dutt P, Jaffe AB, Merdek KD, Hall A, Toksoz D.

Mol Pharmacol. 2004 Dec;66(6):1508-16. Epub 2004 Aug 23.

PMID:
15326221
18.
19.

Role of Lbc RhoGEF in Galpha12/13-induced signals to Rho GTPase.

Dutt P, Nguyen N, Toksoz D.

Cell Signal. 2004 Feb;16(2):201-9.

PMID:
14636890
20.

Activated Galphaq family members induce Rho GTPase activation and Rho-dependent actin filament assembly.

Dutt P, Kjoller L, Giel M, Hall A, Toksoz D.

FEBS Lett. 2002 Nov 20;531(3):565-9.

21.

Association of Lbc Rho guanine nucleotide exchange factor with alpha-catenin-related protein, alpha-catulin/CTNNAL1, supports serum response factor activation.

Park B, Nguyen NT, Dutt P, Merdek KD, Bashar M, Sterpetti P, Tosolini A, Testa JR, Toksoz D.

J Biol Chem. 2002 Nov 22;277(47):45361-70. Epub 2002 Sep 20.

22.

The Rho small GTPase: functions in health and disease.

Toksoz D, Merdek KD.

Histol Histopathol. 2002;17(3):915-27. doi: 10.14670/HH-17.915. Review.

PMID:
12168803
23.

Physical and functional interactions of Galphaq with Rho and its exchange factors.

Sagi SA, Seasholtz TM, Kobiashvili M, Wilson BA, Toksoz D, Brown JH.

J Biol Chem. 2001 May 4;276(18):15445-52. Epub 2001 Feb 6.

24.

A rho exchange factor mediates thrombin and Galpha(12)-induced cytoskeletal responses.

Majumdar M, Seasholtz TM, Buckmaster C, Toksoz D, Brown JH.

J Biol Chem. 1999 Sep 17;274(38):26815-21.

25.

Activation of the Lbc Rho exchange factor proto-oncogene by truncation of an extended C terminus that regulates transformation and targeting.

Sterpetti P, Hack AA, Bashar MP, Park B, Cheng SD, Knoll JH, Urano T, Feig LA, Toksoz D.

Mol Cell Biol. 1999 Feb;19(2):1334-45. Erratum in: Mol Cell Biol 1999 May;19(5):3930.

26.
27.

Distinct roles for DH and PH domains in the Lbc oncogene.

Olson MF, Sterpetti P, Nagata K, Toksoz D, Hall A.

Oncogene. 1997 Dec 4;15(23):2827-31.

28.
29.

Involvement of the small GTPase rho in integrin-mediated activation of mitogen-activated protein kinase.

Renshaw MW, Toksoz D, Schwartz MA.

J Biol Chem. 1996 Sep 6;271(36):21691-4.

30.

Direct involvement of the small GTP-binding protein Rho in lbc oncogene function.

Zheng Y, Olson MF, Hall A, Cerione RA, Toksoz D.

J Biol Chem. 1995 Apr 21;270(16):9031-4.

31.
32.
33.

Distinctive growth requirements and gene expression patterns distinguish progenitor B cells from pre-B cells.

Faust EA, Saffran DC, Toksoz D, Williams DA, Witte ON.

J Exp Med. 1993 Apr 1;177(4):915-23.

34.

Evaluation of two ELISA's for detecting Chlamydia trachomatis from endocervical swabs.

Altaie SS, Meier FA, Centor RM, Wakabongo M, Toksoz D, Harvey KM, Basinger E, Johnson BA, Brookman RR, Dalton HP.

Diagn Microbiol Infect Dis. 1992 Sep-Oct;15(7):579-86.

PMID:
1424514
35.
36.

Effect of Steel factor and leukaemia inhibitory factor on murine primordial germ cells in culture.

Matsui Y, Toksoz D, Nishikawa S, Nishikawa S, Williams D, Zsebo K, Hogan BL.

Nature. 1991 Oct 24;353(6346):750-2.

PMID:
1719421
37.

Ras genes and acute myeloid leukaemia.

Toksoz D, Farr CJ, Marshall CJ.

Br J Haematol. 1989 Jan;71(1):1-6. Review. No abstract available.

PMID:
2644966
38.

ras gene activation in a minor proportion of the blast population in acute myeloid leukemia.

Toksoz D, Farr CJ, Marshall CJ.

Oncogene. 1987;1(4):409-13.

PMID:
3330783
39.

N-ras and human cancer.

McKay IA, Paterson H, Brown R, Toksoz D, Marshall CJ, Hall A.

Anticancer Res. 1986 May-Jun;6(3 Pt B):483-90. Review.

PMID:
3017182
40.

Amino-acid substitutions at codon 13 of the N-ras oncogene in human acute myeloid leukaemia.

Bos JL, Toksoz D, Marshall CJ, Verlaan-de Vries M, Veeneman GH, van der Eb AJ, van Boom JH, Janssen JW, Steenvoorden AC.

Nature. 1985 Jun 27-Jul 3;315(6022):726-30.

PMID:
2989702
41.
42.

Isolation and characterisation of dimethylsulphoxide resistant variants from the human promyeloid cell line HL60.

Bunce CM, Fisher AG, Toksoz D, Brown G.

Exp Hematol. 1983 Oct;11(9):828-33.

PMID:
6641827
43.

Studies of myelopoiesis using monoclonal antibodies and variant lines from the promyeloid cell line HL60.

Brown G, Fisher AG, Bunce CM, Stone PC, Toksoz D.

Haematol Blood Transfus. 1983;28:380-3. No abstract available.

PMID:
6574955
44.

Studies of human myeloid antigens using monoclonal antibodies and variant lines from the promyeloid cell line HL60.

Fisher AG, Bunce CM, Toksoz D, Stone PC, Brown G.

Clin Exp Immunol. 1982 Nov;50(2):374-81.

45.

Variant cell lines from the human promyelocyte line HL60.

Toksoz D, Bunce CM, Stone PC, Michell RH, Brown G.

Leuk Res. 1982;6(4):491-8.

PMID:
6958930
46.

The regulation of hemopoiesis in long-term bone marrow cultures. II. Stimulation and inhibition of stem cell proliferation.

Toksöz D, Dexter TM, Lord BI, Wright EG, Lajtha LG.

Blood. 1980 Jun;55(6):931-6.

PMID:
7378583
47.

The role of cells and their products in the regulation of in vitro stem cell proliferation and granulocyte development.

Dexter TM, Spooncer E, Toksoz D, Lajtha LG.

J Supramol Struct. 1980;13(4):513-24.

PMID:
7230803

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