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Items: 1 to 50 of 208

1.

[Diagnostic targets and exosome sequence analysis of Diamond-Blackfan anemia in Japan].

Toki T, Ito E.

Rinsho Ketsueki. 2018;59(7):945-952. doi: 10.11406/rinketsu.59.945. Japanese.

PMID:
30078807
2.

Correction to: Atypical erythroblastosis in a patient with Diamond-Blackfan anemia who developed del(20q) myelodysplasia.

Sonoda M, Ishimura M, Ichimiya Y, Terashi E, Eguchi K, Sakai Y, Takada H, Hama A, Kanno H, Toki T, Ito E, Ohga S.

Int J Hematol. 2018 Aug;108(2):236. doi: 10.1007/s12185-018-2493-4.

PMID:
29967977
3.

Deep-biosphere methane production stimulated by geofluids in the Nankai accretionary complex.

Ijiri A, Inagaki F, Kubo Y, Adhikari RR, Hattori S, Hoshino T, Imachi H, Kawagucci S, Morono Y, Ohtomo Y, Ono S, Sakai S, Takai K, Toki T, Wang DT, Yoshinaga MY, Arnold GL, Ashi J, Case DH, Feseker T, Hinrichs KU, Ikegawa Y, Ikehara M, Kallmeyer J, Kumagai H, Lever MA, Morita S, Nakamura KI, Nakamura Y, Nishizawa M, Orphan VJ, Røy H, Schmidt F, Tani A, Tanikawa W, Terada T, Tomaru H, Tsuji T, Tsunogai U, Yamaguchi YT, Yoshida N.

Sci Adv. 2018 Jun 13;4(6):eaao4631. doi: 10.1126/sciadv.aao4631. eCollection 2018 Jun.

4.

Evoked potential studies for predicting functional recovery in a case of acute necrotizing encephalopathy.

Onozawa Y, Iwasaki T, Iizuka T, Nonoda Y, Toki T, Obata S, Munekata S, Kanoh Y.

Clin Case Rep. 2018 Mar 8;6(5):813-816. doi: 10.1002/ccr3.1473. eCollection 2018 May.

5.
6.

Tolvaptan alleviates excessive fluid retention of nephrotic diabetic renal failure unresponsive to furosemide.

Takada T, Masaki T, Hoshiyama A, Toki T, Kamata Y, Shichiri M.

Nephrology (Carlton). 2018 Apr 17. doi: 10.1111/nep.13390. [Epub ahead of print]

PMID:
29665203
7.

Atypical erythroblastosis in a patient with Diamond-Blackfan anemia who developed del(20q) myelodysplasia.

Sonoda M, Ishimura M, Ichimiya Y, Terashi E, Eguchi K, Sakai Y, Takada H, Hama A, Kanno H, Toki T, Ito E, Ohga S.

Int J Hematol. 2018 Aug;108(2):228-231. doi: 10.1007/s12185-018-2424-4. Epub 2018 Feb 23. Erratum in: Int J Hematol. 2018 Jul 2;:.

PMID:
29476317
8.

Origin of methane-rich natural gas at the West Pacific convergent plate boundary.

Sano Y, Kinoshita N, Kagoshima T, Takahata N, Sakata S, Toki T, Kawagucci S, Waseda A, Lan T, Wen H, Chen AT, Lee H, Yang TF, Zheng G, Tomonaga Y, Roulleau E, Pinti DL.

Sci Rep. 2017 Nov 15;7(1):15646. doi: 10.1038/s41598-017-15959-5.

9.

Identification and quantification of plasma free salusin-β, an endogenous parasympathomimetic peptide.

Fujimoto K, Hayashi A, Kodera Y, Saito T, Toki T, Ogawa A, Kamata Y, Takano K, Katakami H, Shichiri M.

Sci Rep. 2017 Aug 15;7(1):8275. doi: 10.1038/s41598-017-08288-0.

10.

Atribacteria from the Subseafloor Sedimentary Biosphere Disperse to the Hydrosphere through Submarine Mud Volcanoes.

Hoshino T, Toki T, Ijiri A, Morono Y, Machiyama H, Ashi J, Okamura K, Inagaki F.

Front Microbiol. 2017 Jun 20;8:1135. doi: 10.3389/fmicb.2017.01135. eCollection 2017.

11.

Purification of leukemic blast cells from blood smears using laser microdissection.

Matsuo H, Shiga S, Imai T, Kamikubo Y, Toki T, Terui K, Ito E, Adachi S.

Int J Hematol. 2017 Jul;106(1):55-59. doi: 10.1007/s12185-017-2227-z. Epub 2017 Apr 13.

PMID:
28409329
12.

Developmental changes in the balance of glycolytic ATP production and oxidative phosphorylation in ventricular cells: A simulation study.

Sano HI, Toki T, Naito Y, Tomita M.

J Theor Biol. 2017 Apr 21;419:269-277. doi: 10.1016/j.jtbi.2017.02.019. Epub 2017 Feb 24.

PMID:
28237394
13.

Endemicity of the cosmopolitan mesophilic chemolithoautotroph Sulfurimonas at deep-sea hydrothermal vents.

Mino S, Nakagawa S, Makita H, Toki T, Miyazaki J, Sievert SM, Polz MF, Inagaki F, Godfroy A, Kato S, Watanabe H, Nunoura T, Nakamura K, Imachi H, Watsuji TO, Kojima S, Takai K, Sawabe T.

ISME J. 2017 Apr;11(4):909-919. doi: 10.1038/ismej.2016.178. Epub 2017 Jan 3.

14.

Exome sequencing identified RPS15A as a novel causative gene for Diamond-Blackfan anemia.

Ikeda F, Yoshida K, Toki T, Uechi T, Ishida S, Nakajima Y, Sasahara Y, Okuno Y, Kanezaki R, Terui K, Kamio T, Kobayashi A, Fujita T, Sato-Otsubo A, Shiraishi Y, Tanaka H, Chiba K, Muramatsu H, Kanno H, Ohga S, Ohara A, Kojima S, Kenmochi N, Miyano S, Ogawa S, Ito E.

Haematologica. 2017 Mar;102(3):e93-e96. doi: 10.3324/haematol.2016.153932. Epub 2016 Dec 1. No abstract available.

15.

Diagnostic challenge of Diamond-Blackfan anemia in mothers and children by whole-exome sequencing.

Ichimura T, Yoshida K, Okuno Y, Yujiri T, Nagai K, Nishi M, Shiraishi Y, Ueno H, Toki T, Chiba K, Tanaka H, Muramatsu H, Hara T, Kanno H, Kojima S, Miyano S, Ito E, Ogawa S, Ohga S.

Int J Hematol. 2017 Apr;105(4):515-520. doi: 10.1007/s12185-016-2151-7. Epub 2016 Nov 23.

PMID:
27882484
16.

Topiramate Blood Levels During Polytherapy for Epilepsy in Children.

Toki T, Iwasaki T, Ishii M.

Am J Ther. 2016 Nov 14. [Epub ahead of print]

PMID:
27875371
17.

Correlating blood and urinary concentrations of clobazam doses in Japanese children and adolescents with intractable epilepsy.

Iwasaki T, Nonoda Y, Ishida T, Toki T, Ishii M.

Biomed Chromatogr. 2017 Apr;31(4). doi: 10.1002/bmc.3848. Epub 2016 Oct 3.

PMID:
27595429
18.

Recent advances in inherited bone marrow failure syndrome research.

Ito E, Toki T, Terui K.

Rinsho Ketsueki. 2016 Jul;57(7):882-90. doi: 10.11406/rinketsu.57.882. Japanese.

PMID:
27498735
19.

Comparative Analysis of Microbial Communities in Iron-Dominated Flocculent Mats in Deep-Sea Hydrothermal Environments.

Makita H, Kikuchi S, Mitsunobu S, Takaki Y, Yamanaka T, Toki T, Noguchi T, Nakamura K, Abe M, Hirai M, Yamamoto M, Uematsu K, Miyazaki J, Nunoura T, Takahashi Y, Takai K.

Appl Environ Microbiol. 2016 Sep 16;82(19):5741-55. doi: 10.1128/AEM.01151-16. Print 2016 Oct 1.

20.

Erythrocyte glutathione is a novel biomarker of Diamond-Blackfan anemia.

Utsugisawa T, Uchiyama T, Toki T, Ogura H, Aoki T, Hamaguchi I, Ishiguro A, Ohara A, Kojima S, Ohga S, Ito E, Kanno H.

Blood Cells Mol Dis. 2016 Jul;59:31-6. doi: 10.1016/j.bcmd.2016.03.007. Epub 2016 Apr 11.

PMID:
27282564
21.

Systematic Cellular Disease Models Reveal Synergistic Interaction of Trisomy 21 and GATA1 Mutations in Hematopoietic Abnormalities.

Banno K, Omori S, Hirata K, Nawa N, Nakagawa N, Nishimura K, Ohtaka M, Nakanishi M, Sakuma T, Yamamoto T, Toki T, Ito E, Yamamoto T, Kokubu C, Takeda J, Taniguchi H, Arahori H, Wada K, Kitabatake Y, Ozono K.

Cell Rep. 2016 May 10;15(6):1228-41. doi: 10.1016/j.celrep.2016.04.031. Epub 2016 Apr 28.

22.

ALDH2 polymorphism in patients with Diamond-Blackfan anemia in Japan.

Ikeda F, Toki T, Kanezaki R, Terui K, Yoshida K, Kanno H, Ohga S, Ohara A, Kojima S, Ogawa S, Ito E.

Int J Hematol. 2016 Jan;103(1):112-4. doi: 10.1007/s12185-015-1891-0. Epub 2015 Nov 25. No abstract available.

PMID:
26608366
23.

Preserved High Probability of Overall Survival with Significant Reduction of Chemotherapy for Myeloid Leukemia in Down Syndrome: A Nationwide Prospective Study in Japan.

Taga T, Watanabe T, Tomizawa D, Kudo K, Terui K, Moritake H, Kinoshita A, Iwamoto S, Nakayama H, Takahashi H, Shimada A, Taki T, Toki T, Ito E, Goto H, Koh K, Saito AM, Horibe K, Nakahata T, Tawa A, Adachi S.

Pediatr Blood Cancer. 2016 Feb;63(2):248-54. doi: 10.1002/pbc.25789. Epub 2015 Oct 20.

PMID:
26481183
24.

The Effectiveness of Lamotrigine and Its Blood Levels for Pediatric Epilepsy.

Iwasaki T, Toki T, Nonoda Y, Ishii M.

Am J Ther. 2017 Sep/Oct;24(5):e524-e531. doi: 10.1097/MJT.0000000000000332.

PMID:
26295614
25.

[Molecular mechanisms underlying the pathology of Diamond-Blackfan anemia].

Toki T, Ito E.

Rinsho Ketsueki. 2015 Jul;56(7):867-76. doi: 10.11406/rinketsu.56.867. Japanese.

PMID:
26251151
26.

Transient myeloproliferative disorder with partial trisomy 21.

Takahashi T, Inoue A, Yoshimoto J, Kanamitsu K, Taki T, Imada M, Yamada M, Ninomiya S, Toki T, Terui K, Ito E, Shimada A.

Pediatr Blood Cancer. 2015 Nov;62(11):2021-4. doi: 10.1002/pbc.25624. Epub 2015 Jul 1.

PMID:
26138905
27.

The efficacy of levetiracetam for focal seizures and its blood levels in children.

Iwasaki T, Toki T, Nonoda Y, Ishii M.

Brain Dev. 2015 Sep;37(8):773-9. doi: 10.1016/j.braindev.2014.11.008. Epub 2015 Jan 8.

PMID:
25579248
28.

Loss of function mutations in RPL27 and RPS27 identified by whole-exome sequencing in Diamond-Blackfan anaemia.

Wang R, Yoshida K, Toki T, Sawada T, Uechi T, Okuno Y, Sato-Otsubo A, Kudo K, Kamimaki I, Kanezaki R, Shiraishi Y, Chiba K, Tanaka H, Terui K, Sato T, Iribe Y, Ohga S, Kuramitsu M, Hamaguchi I, Ohara A, Hara J, Goi K, Matsubara K, Koike K, Ishiguro A, Okamoto Y, Watanabe K, Kanno H, Kojima S, Miyano S, Kenmochi N, Ogawa S, Ito E.

Br J Haematol. 2015 Mar;168(6):854-64. doi: 10.1111/bjh.13229. Epub 2014 Nov 25.

PMID:
25424902
29.

Synergistic interaction between wavelength of light and concentration of H₂O₂ in bactericidal activity of photolysis of H₂O₂.

Toki T, Nakamura K, Kurauchi M, Kanno T, Katsuda Y, Ikai H, Hayashi E, Egusa H, Sasaki K, Niwano Y.

J Biosci Bioeng. 2015 Mar;119(3):358-62. doi: 10.1016/j.jbiosc.2014.08.015. Epub 2014 Oct 2.

PMID:
25282638
30.

Acute megakaryoblastic leukemia with acquired trisomy 21 and GATA1 mutations in phenotypically normal children.

Ono R, Hasegawa D, Hirabayashi S, Kamiya T, Yoshida K, Yonekawa S, Ogawa C, Hosoya R, Toki T, Terui K, Ito E, Manabe A.

Eur J Pediatr. 2015 Apr;174(4):525-31. doi: 10.1007/s00431-014-2430-3. Epub 2014 Sep 30. Review.

PMID:
25266042
31.

Down syndrome-associated haematopoiesis abnormalities created by chromosome transfer and genome editing technologies.

Kazuki Y, Yakura Y, Abe S, Osaki M, Kajitani N, Kazuki K, Takehara S, Honma K, Suemori H, Yamazaki S, Sakuma T, Toki T, Shimizu R, Nakauchi H, Yamamoto T, Oshimura M.

Sci Rep. 2014 Aug 27;4:6136. doi: 10.1038/srep06136.

32.

Gene alterations involving the CRLF2-JAK pathway and recurrent gene deletions in Down syndrome-associated acute lymphoblastic leukemia in Japan.

Hanada I, Terui K, Ikeda F, Toki T, Kanezaki R, Sato T, Kamio T, Kudo K, Sasaki S, Takahashi Y, Hayashi Y, Inukai T, Kojima S, Koike K, Kosaka Y, Kobayashi M, Imaizumi M, Mitsui T, Hori H, Hara J, Horibe K, Nagai J, Goto H, Ito E.

Genes Chromosomes Cancer. 2014 Nov;53(11):902-10. doi: 10.1002/gcc.22201. Epub 2014 Jul 16.

PMID:
25044358
33.

A novel inhibitor of I-kappaB kinase beta ameliorates experimental arthritis through downregulation of proinflammatory cytokines in arthritic joints.

Tanaka S, Toki T, Yokoyama M, Shimizu H, Yamasaki T, Yoneda Y, Muro F, Yasukochi T, Iimura S, Morishita K.

Biol Pharm Bull. 2014;37(1):87-95.

34.

The landscape of somatic mutations in Down syndrome-related myeloid disorders.

Yoshida K, Toki T, Okuno Y, Kanezaki R, Shiraishi Y, Sato-Otsubo A, Sanada M, Park MJ, Terui K, Suzuki H, Kon A, Nagata Y, Sato Y, Wang R, Shiba N, Chiba K, Tanaka H, Hama A, Muramatsu H, Hasegawa D, Nakamura K, Kanegane H, Tsukamoto K, Adachi S, Kawakami K, Kato K, Nishimura R, Izraeli S, Hayashi Y, Miyano S, Kojima S, Ito E, Ogawa S.

Nat Genet. 2013 Nov;45(11):1293-9. doi: 10.1038/ng.2759. Epub 2013 Sep 22. Erratum in: Nat Genet. 2013 Dec;45(12):1516.

PMID:
24056718
35.
36.

Biogeography of Persephonella in deep-sea hydrothermal vents of the Western Pacific.

Mino S, Makita H, Toki T, Miyazaki J, Kato S, Watanabe H, Imachi H, Watsuji TO, Nunoura T, Kojima S, Sawabe T, Takai K, Nakagawa S.

Front Microbiol. 2013 Apr 25;4:107. doi: 10.3389/fmicb.2013.00107. eCollection 2013.

37.

Clonal selection in xenografted TAM recapitulates the evolutionary process of myeloid leukemia in Down syndrome.

Saida S, Watanabe K, Sato-Otsubo A, Terui K, Yoshida K, Okuno Y, Toki T, Wang R, Shiraishi Y, Miyano S, Kato I, Morishima T, Fujino H, Umeda K, Hiramatsu H, Adachi S, Ito E, Ogawa S, Ito M, Nakahata T, Heike T.

Blood. 2013 May 23;121(21):4377-87. doi: 10.1182/blood-2012-12-474387. Epub 2013 Mar 12.

38.

Naturally occurring oncogenic GATA1 mutants with internal deletions in transient abnormal myelopoiesis in Down syndrome.

Toki T, Kanezaki R, Kobayashi E, Kaneko H, Suzuki M, Wang R, Terui K, Kanegane H, Maeda M, Endo M, Mizuochi T, Adachi S, Hayashi Y, Yamamoto M, Shimizu R, Ito E.

Blood. 2013 Apr 18;121(16):3181-4. doi: 10.1182/blood-2012-01-405746. Epub 2013 Feb 25.

39.

[Transient myeloproliferative disorder in Down syndrome].

Ito E, Toki T.

Nihon Rinsho. 2012 Apr;70 Suppl 2:687-91. Japanese. No abstract available.

PMID:
23134029
40.

A novel mutation of ribosomal protein S10 gene in a Japanese patient with diamond-Blackfan anemia.

Yazaki M, Kamei M, Ito Y, Konno Y, Wang R, Toki T, Ito E.

J Pediatr Hematol Oncol. 2012 May;34(4):293-5. doi: 10.1097/MPH.0b013e31824a20ab.

PMID:
22510774
41.

Iron-based microbial ecosystem on and below the seafloor: a case study of hydrothermal fields of the southern mariana trough.

Kato S, Nakamura K, Toki T, Ishibashi J, Tsunogai U, Hirota A, Ohkuma M, Yamagishi A.

Front Microbiol. 2012 Mar 15;3:89. doi: 10.3389/fmicb.2012.00089. eCollection 2012.

42.

The habitat disruption induces immune-suppression and oxidative stress in honey bees.

Morimoto T, Kojima Y, Toki T, Komeda Y, Yoshiyama M, Kimura K, Nirasawa K, Kadowaki T.

Ecol Evol. 2011 Oct;1(2):201-17. doi: 10.1002/ece3.21.

43.

Identification of TRIB1 R107L gain-of-function mutation in human acute megakaryocytic leukemia.

Yokoyama T, Toki T, Aoki Y, Kanezaki R, Park MJ, Kanno Y, Takahara T, Yamazaki Y, Ito E, Hayashi Y, Nakamura T.

Blood. 2012 Mar 15;119(11):2608-11. doi: 10.1182/blood-2010-12-324806. Epub 2012 Jan 31.

44.

Extensive gene deletions in Japanese patients with Diamond-Blackfan anemia.

Kuramitsu M, Sato-Otsubo A, Morio T, Takagi M, Toki T, Terui K, Wang R, Kanno H, Ohga S, Ohara A, Kojima S, Kitoh T, Goi K, Kudo K, Matsubayashi T, Mizue N, Ozeki M, Masumi A, Momose H, Takizawa K, Mizukami T, Yamaguchi K, Ogawa S, Ito E, Hamaguchi I.

Blood. 2012 Mar 8;119(10):2376-84. doi: 10.1182/blood-2011-07-368662. Epub 2012 Jan 18.

45.

Thermotomaculum hydrothermale gen. nov., sp. nov., a novel heterotrophic thermophile within the phylum Acidobacteria from a deep-sea hydrothermal vent chimney in the Southern Okinawa Trough.

Izumi H, Nunoura T, Miyazaki M, Mino S, Toki T, Takai K, Sako Y, Sawabe T, Nakagawa S.

Extremophiles. 2012 Mar;16(2):245-53. doi: 10.1007/s00792-011-0425-9. Epub 2012 Jan 3.

PMID:
22212657
46.

Spatial distribution of viruses associated with planktonic and attached microbial communities in hydrothermal environments.

Yoshida-Takashima Y, Nunoura T, Kazama H, Noguchi T, Inoue K, Akashi H, Yamanaka T, Toki T, Yamamoto M, Furushima Y, Ueno Y, Yamamoto H, Takai K.

Appl Environ Microbiol. 2012 Mar;78(5):1311-20. doi: 10.1128/AEM.06491-11. Epub 2011 Dec 30.

47.

Infestation of Japanese native honey bees by tracheal mite and virus from non-native European honey bees in Japan.

Kojima Y, Toki T, Morimoto T, Yoshiyama M, Kimura K, Kadowaki T.

Microb Ecol. 2011 Nov;62(4):895-906. doi: 10.1007/s00248-011-9947-z. Epub 2011 Sep 30.

PMID:
21960435
48.

Discovery of imidazo[1,2-b]pyridazines as IKKβ inhibitors. Part 3: exploration of effective compounds in arthritis models.

Shimizu H, Yamasaki T, Yoneda Y, Muro F, Hamada T, Yasukochi T, Tanaka S, Toki T, Yokoyama M, Morishita K, Iimura S.

Bioorg Med Chem Lett. 2011 Aug 1;21(15):4550-5. doi: 10.1016/j.bmcl.2011.05.115. Epub 2011 Jun 6.

PMID:
21705219
49.

Nrf2 regulates ferroportin 1-mediated iron efflux and counteracts lipopolysaccharide-induced ferroportin 1 mRNA suppression in macrophages.

Harada N, Kanayama M, Maruyama A, Yoshida A, Tazumi K, Hosoya T, Mimura J, Toki T, Maher JM, Yamamoto M, Itoh K.

Arch Biochem Biophys. 2011 Apr 1;508(1):101-9. doi: 10.1016/j.abb.2011.02.001. Epub 2011 Feb 12.

PMID:
21303654
50.

Discovery of imidazo[1,2-b]pyridazines as IKKβ inhibitors. Part 2: improvement of potency in vitro and in vivo.

Shimizu H, Yasumatsu I, Hamada T, Yoneda Y, Yamasaki T, Tanaka S, Toki T, Yokoyama M, Morishita K, Iimura S.

Bioorg Med Chem Lett. 2011 Feb 1;21(3):904-8. doi: 10.1016/j.bmcl.2010.12.078. Epub 2010 Dec 21.

PMID:
21232950

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