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Items: 1 to 50 of 149

1.

Impact of dapagliflozin on left ventricular diastolic function of patients with type 2 diabetic mellitus with chronic heart failure.

Soga F, Tanaka H, Tatsumi K, Mochizuki Y, Sano H, Toki H, Matsumoto K, Shite J, Takaoka H, Doi T, Hirata KI.

Cardiovasc Diabetol. 2018 Oct 8;17(1):132. doi: 10.1186/s12933-018-0775-z.

2.

Lack of deuterium isotope effects in the antidepressant effects of (R)-ketamine in a chronic social defeat stress model.

Zhang K, Toki H, Fujita Y, Ma M, Chang L, Qu Y, Harada S, Nemoto T, Mizuno-Yasuhira A, Yamaguchi JI, Chaki S, Hashimoto K.

Psychopharmacology (Berl). 2018 Nov;235(11):3177-3185. doi: 10.1007/s00213-018-5017-2. Epub 2018 Sep 13.

PMID:
30215218
3.

AMPA Receptor Activation-Independent Antidepressant Actions of Ketamine Metabolite (S)-Norketamine.

Yang C, Kobayashi S, Nakao K, Dong C, Han M, Qu Y, Ren Q, Zhang JC, Ma M, Toki H, Yamaguchi JI, Chaki S, Shirayama Y, Nakazawa K, Manabe T, Hashimoto K.

Biol Psychiatry. 2018 Oct 15;84(8):591-600. doi: 10.1016/j.biopsych.2018.05.007. Epub 2018 May 14.

PMID:
29945718
4.

No Sex-Specific Differences in the Acute Antidepressant Actions of (R)-Ketamine in an Inflammation Model.

Chang L, Toki H, Qu Y, Fujita Y, Mizuno-Yasuhira A, Yamaguchi JI, Chaki S, Hashimoto K.

Int J Neuropsychopharmacol. 2018 Oct 1;21(10):932-937. doi: 10.1093/ijnp/pyy053.

5.

(2R,6R)-Hydroxynorketamine is not essential for the antidepressant actions of (R)-ketamine in mice.

Yamaguchi JI, Toki H, Qu Y, Yang C, Koike H, Hashimoto K, Mizuno-Yasuhira A, Chaki S.

Neuropsychopharmacology. 2018 Aug;43(9):1900-1907. doi: 10.1038/s41386-018-0084-y. Epub 2018 May 3.

PMID:
29802366
6.

Gene expression of A6-like subgroup of ATP-binding cassette transporters in mouse brain parenchyma and microvessels.

Tachikawa M, Toki H, Watanabe M, Tomi M, Hosoya KI, Terasaki T.

Anat Sci Int. 2018 Sep;93(4):456-463. doi: 10.1007/s12565-018-0435-0. Epub 2018 Mar 8.

PMID:
29520568
7.

Physics of epi-thermal boron neutron capture therapy (epi-thermal BNCT).

Seki R, Wakisaka Y, Morimoto N, Takashina M, Koizumi M, Toki H, Fukuda M.

Radiol Phys Technol. 2017 Dec;10(4):387-408. doi: 10.1007/s12194-017-0430-5. Epub 2017 Nov 20. Review.

PMID:
29159536
8.

A rapid and sensitive chiral LC-MS/MS method for the determination of ketamine and norketamine in mouse plasma, brain and cerebrospinal fluid applicable to the stereoselective pharmacokinetic study of ketamine.

Toki H, Ichikawa T, Mizuno-Yasuhira A, Yamaguchi JI.

J Pharm Biomed Anal. 2018 Jan 30;148:288-297. doi: 10.1016/j.jpba.2017.09.033. Epub 2017 Oct 7.

PMID:
29126076
9.

Antidepressant Potential of (R)-Ketamine in Rodent Models: Comparison with (S)-Ketamine.

Fukumoto K, Toki H, Iijima M, Hashihayata T, Yamaguchi JI, Hashimoto K, Chaki S.

J Pharmacol Exp Ther. 2017 Apr;361(1):9-16. doi: 10.1124/jpet.116.239228. Epub 2017 Jan 23. Erratum in: J Pharmacol Exp Ther. 2017 Jul;362(1):1.

10.

Establishment of monoclonal antibodies against cell surface domains of ASCT2/SLC1A5 and their inhibition of glutamine-dependent tumor cell growth.

Suzuki M, Toki H, Furuya A, Ando H.

Biochem Biophys Res Commun. 2017 Jan 22;482(4):651-657. doi: 10.1016/j.bbrc.2016.11.089. Epub 2016 Nov 16.

PMID:
27865832
11.
12.

Novel allelic mutations in murine Serca2 induce differential development of squamous cell tumors.

Toki H, Minowa O, Inoue M, Motegi H, Karashima Y, Ikeda A, Kaneda H, Sakuraba Y, Saiki Y, Wakana S, Suzuki H, Gondo Y, Shiroishi T, Noda T.

Biochem Biophys Res Commun. 2016 Aug 5;476(4):175-182. doi: 10.1016/j.bbrc.2016.04.136. Epub 2016 Apr 27.

PMID:
27131742
13.

Mouse models for ROS1-fusion-positive lung cancers and their application to the analysis of multikinase inhibitor efficiency.

Inoue M, Toki H, Matsui J, Togashi Y, Dobashi A, Fukumura R, Gondo Y, Minowa O, Tanaka N, Mori S, Takeuchi K, Noda T.

Carcinogenesis. 2016 May;37(5):452-60. doi: 10.1093/carcin/bgw028. Epub 2016 Mar 10.

PMID:
26964870
14.

Comprehensive Functional Assessment of Right-Sided Heart Using Speckle Tracking Strain for Patients with Pulmonary Hypertension.

Fukuda Y, Tanaka H, Ryo-Koriyama K, Motoji Y, Sano H, Shimoura H, Ooka J, Toki H, Sawa T, Mochizuki Y, Matsumoto K, Emoto N, Hirata K.

Echocardiography. 2016 Jul;33(7):1001-8. doi: 10.1111/echo.13205. Epub 2016 Feb 26.

PMID:
26920332
15.

Identification of Reliable Components in Multivariate Curve Resolution-Alternating Least Squares (MCR-ALS): a Data-Driven Approach across Metabolic Processes.

Motegi H, Tsuboi Y, Saga A, Kagami T, Inoue M, Toki H, Minowa O, Noda T, Kikuchi J.

Sci Rep. 2015 Nov 4;5:15710. doi: 10.1038/srep15710.

16.

Left ventricular dyssynergy and dispersion as determinant factors of fatal ventricular arrhythmias in patients with mildly reduced ejection fraction.

Matsuzoe H, Tanaka H, Matsumoto K, Toki H, Shimoura H, Ooka J, Sano H, Sawa T, Motoji Y, Mochizuki Y, Ryo K, Fukuzawa K, Yoshida A, Hirata K.

Eur Heart J Cardiovasc Imaging. 2016 Mar;17(3):334-42. doi: 10.1093/ehjci/jev172. Epub 2015 Jul 9.

PMID:
26160402
17.

Association of peripheral nerve conduction in diabetic neuropathy with subclinical left ventricular systolic dysfunction.

Mochizuki Y, Tanaka H, Matsumoto K, Sano H, Toki H, Shimoura H, Ooka J, Sawa T, Motoji Y, Ryo K, Hirota Y, Ogawa W, Hirata K.

Cardiovasc Diabetol. 2015 May 7;14:47. doi: 10.1186/s12933-015-0213-4.

18.

Cell motion predicts human epidermal stemness.

Nanba D, Toki F, Tate S, Imai M, Matsushita N, Shiraishi K, Sayama K, Toki H, Higashiyama S, Barrandon Y.

J Cell Biol. 2015 Apr 27;209(2):305-15. doi: 10.1083/jcb.201409024. Epub 2015 Apr 20.

19.

Clinical features of subclinical left ventricular systolic dysfunction in patients with diabetes mellitus.

Mochizuki Y, Tanaka H, Matsumoto K, Sano H, Toki H, Shimoura H, Ooka J, Sawa T, Motoji Y, Ryo K, Hirota Y, Ogawa W, Hirata K.

Cardiovasc Diabetol. 2015 Apr 17;14:37. doi: 10.1186/s12933-015-0201-8.

20.

β-CateninC429S mice exhibit sterility consequent to spatiotemporally sustained Wnt signalling in the internal genitalia.

Murata T, Ishitsuka Y, Karouji K, Kaneda H, Toki H, Nakai Y, Makino S, Fukumura R, Kotaki H, Wakana S, Noda T, Gondo Y.

Sci Rep. 2014 Nov 7;4:6959. doi: 10.1038/srep06959.

21.

Novel retinoblastoma mutation abrogating the interaction to E2F2/3, but not E2F1, led to selective suppression of thyroid tumors.

Toki H, Inoue M, Minowa O, Motegi H, Saiki Y, Wakana S, Masuya H, Gondo Y, Shiroishi T, Yao R, Noda T.

Cancer Sci. 2014 Oct;105(10):1360-8. doi: 10.1111/cas.12495. Epub 2014 Sep 29.

22.

Autoimmune disorders associated with gain of function of the intracellular sensor MDA5.

Funabiki M, Kato H, Miyachi Y, Toki H, Motegi H, Inoue M, Minowa O, Yoshida A, Deguchi K, Sato H, Ito S, Shiroishi T, Takeyasu K, Noda T, Fujita T.

Immunity. 2014 Feb 20;40(2):199-212. doi: 10.1016/j.immuni.2013.12.014. Epub 2014 Feb 13.

23.
24.

A small compound targeting TACC3 revealed its different spatiotemporal contributions for spindle assembly in cancer cells.

Yao R, Kondoh Y, Natsume Y, Yamanaka H, Inoue M, Toki H, Takagi R, Shimizu T, Yamori T, Osada H, Noda T.

Oncogene. 2014 Aug 14;33(33):4242-52. doi: 10.1038/onc.2013.382. Epub 2013 Sep 30.

PMID:
24077290
25.

Novel mouse model for Gardner syndrome generated by a large-scale N-ethyl-N-nitrosourea mutagenesis program.

Toki H, Inoue M, Motegi H, Minowa O, Kanda H, Yamamoto N, Ikeda A, Karashima Y, Matsui J, Kaneda H, Miura I, Suzuki T, Wakana S, Masuya H, Gondo Y, Shiroishi T, Akiyama T, Yao R, Noda T.

Cancer Sci. 2013 Jul;104(7):937-44. doi: 10.1111/cas.12161. Epub 2013 May 18.

26.

Hair organ regeneration via the bioengineered hair follicular unit transplantation.

Asakawa K, Toyoshima KE, Ishibashi N, Tobe H, Iwadate A, Kanayama T, Hasegawa T, Nakao K, Toki H, Noguchi S, Ogawa M, Sato A, Tsuji T.

Sci Rep. 2012;2:424. doi: 10.1038/srep00424. Epub 2012 May 28.

27.

Fully functional hair follicle regeneration through the rearrangement of stem cells and their niches.

Toyoshima KE, Asakawa K, Ishibashi N, Toki H, Ogawa M, Hasegawa T, Irié T, Tachikawa T, Sato A, Takeda A, Tsuji T.

Nat Commun. 2012 Apr 17;3:784. doi: 10.1038/ncomms1784.

28.

Single follicular unit transplantation reconstructs arrector pili muscle and nerve connections and restores functional hair follicle piloerection.

Sato A, Toyoshima KE, Toki H, Ishibashi N, Asakawa K, Iwadate A, Kanayama T, Tobe H, Takeda A, Tsuji T.

J Dermatol. 2012 Aug;39(8):682-7. doi: 10.1111/j.1346-8138.2012.01505.x. Epub 2012 Mar 2.

PMID:
22380609
29.

Disruption of Tacc3 function leads to in vivo tumor regression.

Yao R, Natsume Y, Saiki Y, Shioya H, Takeuchi K, Yamori T, Toki H, Aoki I, Saga T, Noda T.

Oncogene. 2012 Jan 12;31(2):135-48. doi: 10.1038/onc.2011.235. Epub 2011 Jun 20.

PMID:
21685933
30.

Contact between dermal papilla cells and dermal sheath cells enhances the ability of DPCs to induce hair growth.

Yamao M, Inamatsu M, Ogawa Y, Toki H, Okada T, Toyoshima KE, Yoshizato K.

J Invest Dermatol. 2010 Dec;130(12):2707-18. doi: 10.1038/jid.2010.241. Epub 2010 Aug 19. Erratum in: J Invest Dermatol. 2012 Jul;132(7):1938.

31.

Establishment of a novel monoclonal antibody against LGR5.

Sasaki Y, Kosaka H, Usami K, Toki H, Kawai H, Shiraishi N, Ota T, Nakamura K, Furuya A, Satoh M, Hasegawa K, Masuda K.

Biochem Biophys Res Commun. 2010 Apr 9;394(3):498-502. doi: 10.1016/j.bbrc.2010.02.166. Epub 2010 Mar 1.

PMID:
20197059
32.

SDOP-DB: a comparative standardized-protocol database for mouse phenotypic analyses.

Tanaka N, Waki K, Kaneda H, Suzuki T, Yamada I, Furuse T, Kobayashi K, Motegi H, Toki H, Inoue M, Minowa O, Noda T, Takao K, Miyakawa T, Takahashi A, Koide T, Wakana S, Masuya H.

Bioinformatics. 2010 Apr 15;26(8):1133-4. doi: 10.1093/bioinformatics/btq095. Epub 2010 Mar 1.

33.

Multiple extensor tendon ruptures caused by tophaceous gout.

Iwamoto T, Toki H, Ikari K, Yamanaka H, Momohara S.

Mod Rheumatol. 2010 Apr;20(2):210-2. doi: 10.1007/s10165-009-0258-x. Epub 2009 Dec 16.

PMID:
20013296
34.

Introduction to the Japan Mouse Clinic at the RIKEN BioResource Center.

Wakana S, Suzuki T, Furuse T, Kobayashi K, Miura I, Kaneda H, Yamada I, Motegi H, Toki H, Inoue M, Minowa O, Noda T, Waki K, Tanaka N, Masuya H, Obata Y.

Exp Anim. 2009 Oct;58(5):443-50. Review.

35.

Prediction of wrist prognosis in patients with early rheumatoid arthritis according to radiographic classification.

Murakoshi K, Toki H, Horiuchi T, Saito S.

J Hand Surg Am. 2009 May-Jun;34(5):824-31. doi: 10.1016/j.jhsa.2009.01.016.

PMID:
19410985
36.

Declining use of synovectomy surgery for patients with rheumatoid arthritis in Japan.

Momohara S, Ikari K, Mochizuki T, Kawamura K, Tsukahara S, Toki H, Hara M, Kamatani N, Yamanaka H, Tomatsu T.

Ann Rheum Dis. 2009 Feb;68(2):291-2. doi: 10.1136/ard.2008.087940. No abstract available.

PMID:
19139210
37.

Infusion reaction to infliximab in a patient with rheumatoid arthritis after discontinuation over 1 year and readministration.

Toki H, Momohara S, Tsukahara S, Ikari K.

J Rheumatol. 2008 Sep;35(9):1896-7; author reply 1897. No abstract available.

PMID:
18785300
38.

Risk factors for wrist surgery in rheumatoid arthritis.

Momohara S, Inoue E, Ikari K, Tsukahara S, Kawamura K, Toki H, Hara M, Kamatani N, Yamanaka H, Tomatsu T.

Clin Rheumatol. 2008 Nov;27(11):1387-91. doi: 10.1007/s10067-008-0928-7. Epub 2008 May 24.

PMID:
18500434
39.

Iliopsoas bursitis-associated femoral neuropathy exacerbated after internal fixation of an intertrochanteric hip fracture in rheumatoid arthritis: a case report.

Tokita A, Ikari K, Tsukahara S, Toki H, Miyawaki M, Mochizuki T, Kawamura K, Tomatsu T, Momohara S.

Mod Rheumatol. 2008;18(4):394-8. doi: 10.1007/s10165-008-0060-1. Epub 2008 Apr 18.

PMID:
18421416
40.

Return of infliximab efficacy after total knee arthroplasty in a patient with rheumatoid arthritis.

Toki H, Momohara S, Ikari K, Kawamura K, Tsukahara S, Mochizuki T, Sato E, Yamanaka H.

Clin Rheumatol. 2008 Apr;27(4):549-50. doi: 10.1007/s10067-008-0858-4. Epub 2008 Feb 26. No abstract available.

PMID:
18299787
41.

Risk factors for total knee arthroplasty in rheumatoid arthritis.

Momohara S, Inoue E, Ikari K, Kawamura K, Tsukahara S, Mochizuki T, Toki H, Miyawaki M, Saito S, Hara M, Kamatani N, Yamanaka H, Tomatsu T.

Mod Rheumatol. 2007;17(6):476-80. Epub 2007 Dec 20.

PMID:
18084699
42.

A novel dominant-negative mutation in Gdf5 generated by ENU mutagenesis impairs joint formation and causes osteoarthritis in mice.

Masuya H, Nishida K, Furuichi T, Toki H, Nishimura G, Kawabata H, Yokoyama H, Yoshida A, Tominaga S, Nagano J, Shimizu A, Wakana S, Gondo Y, Noda T, Shiroishi T, Ikegawa S.

Hum Mol Genet. 2007 Oct 1;16(19):2366-75. Epub 2007 Jul 26.

PMID:
17656374
43.

Gene expression profiles of ATP-binding cassette transporter A and C subfamilies in mouse retinal vascular endothelial cells.

Tachikawa M, Toki H, Tomi M, Hosoya K.

Microvasc Res. 2008 Jan;75(1):68-72. Epub 2007 May 18.

PMID:
17574281
44.

A phase II study of VEPA/FEPP chemotherapy for aggressive lymphoma in elderly patients: Japan Clinical Oncology Group Study JCOG9203.

Mizoroki F, Hirose Y, Sano M, Fukuda H, Tobinai K, Nakata M, Taniwaki M, Kawano F, Uozumi K, Sawada K, Fukuhara S, Nasu K, Ohno Y, Toki H, Togawa A, Kikuchi M, Hotta T, Shimoyama M; Japan Clinical Oncology Group-Lymphoma Study Group (JCOG-LSG).

Int J Hematol. 2006 Jan;83(1):55-62.

PMID:
16443554
45.

A randomized controlled trial investigating the survival benefit of dose-intensified multidrug combination chemotherapy (LSG9) for intermediate- or high-grade non-Hodgkin's lymphoma: Japan Clinical Oncology Group Study 9002.

Kinoshita T, Hotta T, Tobinai K, Kobayashi T, Ishizuka N, Tomonaga M, Sai T, Ohno Y, Kasai M, Ogura M, Mikuni C, Toki H, Sano M, Masaki Y, Ohtsu T, Matsuno Y, Takenaka T, Shirakawa S, Shimoyama M; Japan Clinical Oncology Group.

Int J Hematol. 2004 Nov;80(4):341-50.

PMID:
15615259
46.

Development and implementation of a database system to manage a large-scale mouse ENU-mutagenesis program.

Masuya H, Nakai Y, Motegi H, Niinaya N, Kida Y, Kaneko Y, Aritake H, Suzuki N, Ishii J, Koorikawa K, Suzuki T, Inoue M, Kobayashi K, Toki H, Wada Y, Kaneda H, Ishijima J, Takahashi KR, Minowa O, Noda T, Wakana S, Gondo Y, Shiroishi T.

Mamm Genome. 2004 May;15(5):404-11.

PMID:
15170230
47.

A series of maturity onset diabetes of the young, type 2 (MODY2) mouse models generated by a large-scale ENU mutagenesis program.

Inoue M, Sakuraba Y, Motegi H, Kubota N, Toki H, Matsui J, Toyoda Y, Miwa I, Terauchi Y, Kadowaki T, Shigeyama Y, Kasuga M, Adachi T, Fujimoto N, Matsumoto R, Tsuchihashi K, Kagami T, Inoue A, Kaneda H, Ishijima J, Masuya H, Suzuki T, Wakana S, Gondo Y, Minowa O, Shiroishi T, Noda T.

Hum Mol Genet. 2004 Jun 1;13(11):1147-57. Epub 2004 Apr 21.

PMID:
15102714
48.

Over-expression of short isoforms of Helios in patients with adult T-cell leukaemia/lymphoma.

Fujii K, Ishimaru F, Nakase K, Tabayashi T, Kozuka T, Naoki K, Miyahara M, Toki H, Kitajima K, Harada M, Tanimoto M.

Br J Haematol. 2003 Mar;120(6):986-9.

PMID:
12648068
49.

Autoimmune neutropenia associated with multiple sclerosis.

Kozuka T, Kojima K, Kaneda K, Takenaka K, Manabe Y, Hirata Y, Okuma S, Toki H, Tanimoto M.

Intern Med. 2003 Jan;42(1):102-4.

50.

[Early phase II clinical trial of amrubicin hydrochloride in patients with malignant lymphoma].

Masaoka T, Ogawa M, Inoue K, Sanpi K, Kuraishi Y, Toki H, Tamura K, Takagi T, Shibata A, Hirano M, Ezaki K, Shirakawa S, Matsuda T, Kimura I.

Gan To Kagaku Ryoho. 2001 Nov;28(12):1857-65. Japanese.

PMID:
11729478

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