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An antiquated contraindication for minimally invasive lung surgery: No place to staple the bronchus.

Coşgun T, Kaba E, Ayalp K, Toker A.

Turk Gogus Kalp Damar Cerrahisi Derg. 2019 Oct 23;27(4):521-525. doi: 10.5606/tgkdc.dergisi.2019.17315. eCollection 2019 Oct.


Evaluation of rat major celluler prion protein for early diagnosis in experimental rat brain trauma model.

Kural A, Tekin Neijmann S, Toker A, Doğan H, Sever N, Sarıkaya S.

Ulus Travma Acil Cerrahi Derg. 2020 Jan;26(1):1-8. doi: 10.5505/tjtes.2018.46923.


Discovery of an AKT Degrader with Prolonged Inhibition of Downstream Signaling.

You I, Erickson EC, Donovan KA, Eleuteri NA, Fischer ES, Gray NS, Toker A.

Cell Chem Biol. 2020 Jan 16;27(1):66-73.e7. doi: 10.1016/j.chembiol.2019.11.014. Epub 2019 Dec 16.


Tumor cell expression of B7-H4 correlates with higher frequencies of tumor-infiltrating APCs and higher CXCL17 expression in human epithelial ovarian cancer.

MacGregor HL, Garcia-Batres C, Sayad A, Elia A, Berman HK, Toker A, Katz SR, Shaw PA, Clarke BA, Crome SQ, Robert-Tissot C, Bernardini MQ, Nguyen LT, Ohashi PS.

Oncoimmunology. 2019 Sep 30;8(12):e1665460. doi: 10.1080/2162402X.2019.1665460. eCollection 2019.


Double trouble for cancer gene.

Toker A.

Science. 2019 Nov 8;366(6466):685-686. doi: 10.1126/science.aaz4016. No abstract available.


Dynamic Imprinting of the Treg Cell-Specific Epigenetic Signature in Developing Thymic Regulatory T Cells.

Herppich S, Toker A, Pietzsch B, Kitagawa Y, Ohkura N, Miyao T, Floess S, Hori S, Sakaguchi S, Huehn J.

Front Immunol. 2019 Oct 11;10:2382. doi: 10.3389/fimmu.2019.02382. eCollection 2019.


Effects of the storage of breast milk at different temperatures on total antioxidant capacity, total oxidant status, and paraoxonase-1 level.

Konak M, Minici M, Tarakçı N, Altunhan H, Toker A, Örs R.

Turk J Pediatr. 2019;61(1):1-6. doi: 10.24953/turkjped.2019.01.001.


Successful Sleeve Resection as a Marker for Proficiency for Robotic Pulmonary Resection.

Cosgun T, Kaba E, Ayalp K, Toker A.

Thorac Cardiovasc Surg. 2019 Sep 15. doi: 10.1055/s-0039-1696952. [Epub ahead of print]


Haemangioendothelioma: a disease with surgical options from robotic surgery to open superior vena cava replacement.

Cosgun T, Kaba E, Ayalp K, Elbegi IC, Toker A.

Interact Cardiovasc Thorac Surg. 2019 Sep 1;29(3):449-452. doi: 10.1093/icvts/ivz109.


Turning the Tide Against Regulatory T Cells.

Han S, Toker A, Liu ZQ, Ohashi PS.

Front Oncol. 2019 Apr 16;9:279. doi: 10.3389/fonc.2019.00279. eCollection 2019. Review.


Robotic thymectomy for myasthenia gravis.

Kaba E, Cosgun T, Ayalp K, Toker A.

Ann Cardiothorac Surg. 2019 Mar;8(2):288-291. doi: 10.21037/acs.2019.02.02. No abstract available.


Effectiveness of Video-Assisted Thoracoscopic Surgery in Undiagnosed Exudative Pleural Effusions.

Dadaş E, Erdoğdu E, Toker A, Ersöz M, Okay T.

Turk Thorac J. 2019 Apr 9;20(3):188-191. doi: 10.5152/TurkThoracJ.2018.18133.


Society for Translational Medicine Expert consensus on the selection of surgical approaches in the management of thoracic esophageal carcinoma.

Mao Y, Yu Z, You B, Fang W, Badgwell B, Berry MF, Ceppa DP, Chen C, Chen H, Cuesta MA, D'Journo XB, Eslick GD, Fu J, Fu X, Gao S, He J, He J, Huang Y, Jiang G, Jiang Z, Kim JY, Li D, Li H, Li S, Liu D, Liu L, Liu Y, Li X, Li Y, Mao W, Molena D, Morse CR, Novoa NM, Tan L, Tan Q, Toker A, Tong T, Wang Q, Weksler B, Xu L, Xu S, Yan T, Zhang L, Zhang X, Zhang X, Zhang Z, Zhi X, Zhou Q.

J Thorac Dis. 2019 Jan;11(1):319-328. doi: 10.21037/jtd.2018.12.07. Review. No abstract available.


Can YKL-40 be an Inflammatory Biomarker in Vitamin D Deficiency?

Can U, Uysal S, Ruveyda Ugur A, Toker A, Aslan U, Taha Hidayetoglu B.

Int J Vitam Nutr Res. 2019 Nov;89(5-6):309-313. doi: 10.1024/0300-9831/a000545. Epub 2019 Feb 26.


AKT methylation by SETDB1 promotes AKT kinase activity and oncogenic functions.

Guo J, Dai X, Laurent B, Zheng N, Gan W, Zhang J, Guo A, Yuan M, Liu P, Asara JM, Toker A, Shi Y, Pandolfi PP, Wei W.

Nat Cell Biol. 2019 Feb;21(2):226-237. doi: 10.1038/s41556-018-0261-6. Epub 2019 Jan 28.


Soluble Tumor Necrosis Factor (TNF)-Like Weak Inducer of Apoptosis (Tweak) Independently Predicts Subclinical Atherosclerosis in Behcet's Disease.

Icli A, Cure MC, Cure E, Arslan S, Unal M, Sakiz D, Ozucan M, Toker A, Turkmen K, Kucuk A.

Acta Medica (Hradec Kralove). 2018;61(3):86-92. doi: 10.14712/18059694.2018.123.


Pulmonary Arterial Bypass Surgery for Fibrosing Mediastinitis Causing Severe Pulmonary Hypertension.

Cimenoglu B, Ozkan B, Basaran M, Toker A.

Ann Thorac Surg. 2019 Jun;107(6):e411-e413. doi: 10.1016/j.athoracsur.2018.09.067. Epub 2018 Nov 14.


PI 3-Kinase Signaling: AKTing up inside the Cell.

Toker A, Dibble CC.

Mol Cell. 2018 Sep 20;71(6):875-876. doi: 10.1016/j.molcel.2018.09.006.


Regulatory T Cells in Ovarian Cancer Are Characterized by a Highly Activated Phenotype Distinct from that in Melanoma.

Toker A, Nguyen LT, Stone SC, Yang SYC, Katz SR, Shaw PA, Clarke BA, Ghazarian D, Al-Habeeb A, Easson A, Leong WL, McCready DR, Reedijk M, Guidos CJ, Pugh TJ, Bernardini MQ, Ohashi PS.

Clin Cancer Res. 2018 Nov 15;24(22):5685-5696. doi: 10.1158/1078-0432.CCR-18-0554. Epub 2018 Jul 31.


Prognostic significance of carbonic anhydrase IX overexpression in stage III non-small cell lung cancer patients after neoadjuvant treatment.

Ibis K, Saglam S, Saglam EK, Firat P, Yilmazbayhan D, Toker A, Ozkan B, Hancer VS, Buyukdogan M, Disci R, Pilanci KN.

Pathol Res Pract. 2018 Sep;214(9):1291-1296. doi: 10.1016/j.prp.2018.07.010. Epub 2018 Jul 11.


Robotic resection of Stage III lung cancer: an international retrospective study.

Veronesi G, Park B, Cerfolio R, Dylewski M, Toker A, Fontaine JP, Hanna WC, Morenghi E, Novellis P, Velez-Cubian FO, Amaral MH, Dieci E, Alloisio M, Toloza EM.

Eur J Cardiothorac Surg. 2018 Nov 1;54(5):912-919. doi: 10.1093/ejcts/ezy166.


Skp2-dependent reactivation of AKT drives resistance to PI3K inhibitors.

Clement E, Inuzuka H, Nihira NT, Wei W, Toker A.

Sci Signal. 2018 Mar 13;11(521). pii: eaao3810. doi: 10.1126/scisignal.aao3810.


Outcomes from the Delphi process of the Thoracic Robotic Curriculum Development Committee.

Veronesi G, Dorn P, Dunning J, Cardillo G, Schmid RA, Collins J, Baste JM, Limmer S, Shahin GMM, Egberts JH, Pardolesi A, Meacci E, Stamenkovic S, Casali G, Rueckert JC, Taurchini M, Santelmo N, Melfi F, Toker A.

Eur J Cardiothorac Surg. 2018 Jun 1;53(6):1173-1179. doi: 10.1093/ejcts/ezx466.


Salvage thoracic surgery in patients with lung cancer: potential indications and benefits.

Kaba E, Ozyurtkan MO, Ayalp K, Cosgun T, Alomari MR, Toker A.

J Cardiothorac Surg. 2018 Jan 22;13(1):13. doi: 10.1186/s13019-018-0693-x.


Oxygen Uptake Efficiency Slope and Prediction of Post-operative Morbidity and Mortality in Patients with Lung Cancer.

Yakal S, Sofyalı S, Özkan B, Yıldız S, Toker A, Kasikcioglu E.

Lung. 2018 Apr;196(2):255-262. doi: 10.1007/s00408-018-0085-y. Epub 2018 Jan 18.


Serum levels of cortisol, dehydroepiandrosterone, and oxytocin in children with attention-deficit/hyperactivity disorder combined presentation with and without comorbid conduct disorder.

Işık Ü, Bilgiç A, Toker A, Kılınç I.

Psychiatry Res. 2018 Mar;261:212-219. doi: 10.1016/j.psychres.2017.12.076. Epub 2018 Jan 2.


Oncogenic PI3K promotes methionine dependency in breast cancer cells through the cystine-glutamate antiporter xCT.

Lien EC, Ghisolfi L, Geck RC, Asara JM, Toker A.

Sci Signal. 2017 Dec 19;10(510). pii: eaao6604. doi: 10.1126/scisignal.aao6604.


Role of Surgery in the Treatment of Masaoka Stage IVa Thymoma.

Kaba E, Ozkan B, Erus S, Duman S, Cimenoglu B, Toker A.

Ann Thorac Cardiovasc Surg. 2018 Feb 20;24(1):6-12. doi: 10.5761/atcs.oa.17-00108. Epub 2017 Dec 8.


Identifying and Targeting Sporadic Oncogenic Genetic Aberrations in Mouse Models of Triple-Negative Breast Cancer.

Liu H, Murphy CJ, Karreth FA, Emdal KB, White FM, Elemento O, Toker A, Wulf GM, Cantley LC.

Cancer Discov. 2018 Mar;8(3):354-369. doi: 10.1158/2159-8290.CD-17-0679. Epub 2017 Dec 4. Erratum in: Cancer Discov. 2018 Aug;8(8):1044.


Nodal upstaging: effects of instrumentation and three-dimensional view in clinical stage I lung cancer.

Toker A, Özyurtkan MO, Kaba E.

J Vis Surg. 2017 May 30;3:76. doi: 10.21037/jovs.2017.04.05. eCollection 2017. Review.


Robotic thymectomy-a new approach for thymus.

Kaba E, Cosgun T, Ayalp K, Alomari MR, Toker A.

J Vis Surg. 2017 May 8;3:67. doi: 10.21037/jovs.2017.03.28. eCollection 2017. Review.


What happens while learning robotic lobectomy for lung cancer?

Özyurtkan MO, Kaba E, Toker A.

J Vis Surg. 2017 Mar 10;3:27. doi: 10.21037/jovs.2017.02.02. eCollection 2017. Review.


Technological innovation in video-assisted thoracic surgery.

Özyurtkan MO, Kaba E, Toker A.

J Vis Surg. 2017 Feb 15;3:20. doi: 10.21037/jovs.2017.01.03. eCollection 2017.


Robotic lung resections: video-assisted thoracic surgery based approach.

Toker A, Kaba E, Ayalp K, Özyurtkan MO.

J Vis Surg. 2017 Feb 13;3:15. doi: 10.21037/jovs.2017.01.08. eCollection 2017. Review.


Prompt Response to Prednisone Predicts Benign Course in MuSK-MG.

Gungor-Tuncer O, Yilmaz V, Toker A, Saruhan-Direskeneli G, Gulsen-Parman Y, Oflazer-Serdaroglu P, Deymeer F.

Eur Neurol. 2017;78(3-4):137-142. doi: 10.1159/000479228. Epub 2017 Jul 28.


Effects of Carvacrol on Survival, Mesenteric Blood Flow, Aortic Function and Multiple Organ Injury in a Murine Model of Polymicrobial Sepsis.

Ozer EK, Goktas MT, Toker A, Bariskaner H, Ugurluoglu C, Iskit AB.

Inflammation. 2017 Oct;40(5):1654-1663. doi: 10.1007/s10753-017-0605-6.


The Importance of Liver-Fatty Acid Binding Protein in Diagnosis of Liver Damage in Patients with Acute Hepatitis.

Cakir OO, Toker A, Ataseven H, Demir A, Polat H.

J Clin Diagn Res. 2017 Apr;11(4):OC17-OC21. doi: 10.7860/JCDR/2017/24958.9621. Epub 2017 Apr 1.


Thymoquinone protects against the sepsis induced mortality, mesenteric hypoperfusion, aortic dysfunction and multiple organ damage in rats.

Ozer EK, Goktas MT, Toker A, Pehlivan S, Bariskaner H, Ugurluoglu C, Iskit AB.

Pharmacol Rep. 2017 Aug;69(4):683-690. doi: 10.1016/j.pharep.2017.02.021. Epub 2017 Mar 24.


Infliximab alleviates the mortality, mesenteric hypoperfusion, aortic dysfunction, and multiple organ damage in septic rats.

Ozer EK, Goktas MT, Kilinc I, Toker A, Bariskaner H, Ugurluoglu C, Iskit AB.

Can J Physiol Pharmacol. 2017 Jul;95(7):866-872. doi: 10.1139/cjpp-2016-0628. Epub 2017 Apr 29.


AKT/PKB Signaling: Navigating the Network.

Manning BD, Toker A.

Cell. 2017 Apr 20;169(3):381-405. doi: 10.1016/j.cell.2017.04.001. Review.


Unique properties of thymic antigen-presenting cells promote epigenetic imprinting of alloantigen-specific regulatory T cells.

Garg G, Nikolouli E, Hardtke-Wolenski M, Toker A, Ohkura N, Beckstette M, Miyao T, Geffers R, Floess S, Gerdes N, Lutgens E, Osterloh A, Hori S, Sakaguchi S, Jaeckel E, Huehn J.

Oncotarget. 2017 May 30;8(22):35542-35557. doi: 10.18632/oncotarget.16221.


A benchmarking project on the quality of previous guidelines about the management of malignant pleural effusion from the European Society of Thoracic Surgeons (ESTS) Pleural Diseases Working Group.

Bertolaccini L, Bedetti B, Brunelli A, Marinova K, Raveglia F, Rocco G, Shargall Y, Solli P, Varela G, Papagiannopoulos K, Kuzdzal J, Massard G, Ruffini E, Falcoz PE, Martinez-Barenys C, Opitz I, Batirel HF, Toker A, Scarci M; Members of the ESTS Pleural Disease Working Group.

Eur J Cardiothorac Surg. 2017 Aug 1;52(2):356-362. doi: 10.1093/ejcts/ezx089.


Cross-talk between the CK2 and AKT signaling pathways in cancer.

Ruzzene M, Bertacchini J, Toker A, Marmiroli S.

Adv Biol Regul. 2017 May;64:1-8. doi: 10.1016/j.jbior.2017.03.002. Epub 2017 Mar 28. Review.


PI3K signaling in cancer: beyond AKT.

Lien EC, Dibble CC, Toker A.

Curr Opin Cell Biol. 2017 Apr;45:62-71. doi: 10.1016/ Epub 2017 Mar 24. Review.


Adaptive Reprogramming of De Novo Pyrimidine Synthesis Is a Metabolic Vulnerability in Triple-Negative Breast Cancer.

Brown KK, Spinelli JB, Asara JM, Toker A.

Cancer Discov. 2017 Apr;7(4):391-399. doi: 10.1158/2159-8290.CD-16-0611. Epub 2017 Mar 2. Erratum in: Cancer Discov. 2017 Jul;7(7):782.


Pentraxin-3 is a PI3K signaling target that promotes stem cell-like traits in basal-like breast cancers.

Thomas C, Henry W, Cuiffo BG, Collmann AY, Marangoni E, Benhamo V, Bhasin MK, Fan C, Fuhrmann L, Baldwin AS, Perou C, Vincent-Salomon A, Toker A, Karnoub AE.

Sci Signal. 2017 Feb 21;10(467). pii: eaah4674. doi: 10.1126/scisignal.aah4674.


The SCFβ-TRCP E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis.

Shimizu K, Fukushima H, Ogura K, Lien EC, Nihira NT, Zhang J, North BJ, Guo A, Nagashima K, Nakagawa T, Hoshikawa S, Watahiki A, Okabe K, Yamada A, Toker A, Asara JM, Fukumoto S, Nakayama KI, Nakayama K, Inuzuka H, Wei W.

Sci Signal. 2017 Jan 3;10(460). pii: eaah4117. doi: 10.1126/scisignal.aah4117.


Current practices in the management of malignant pleural effusions: a survey among members of the European Society of Thoracic Surgeons.

Scarci M, Caruana E, Bertolaccini L, Bedetti B, Brunelli A, Varela G, Papagiannopoulos K, Kuzdzal J, Massard G, Ruffini E, Falcoz PE, Opitz I, Batirel H, Toker A, Rocco G; ESTS Malignant Pleural Effusion Working Group.

Interact Cardiovasc Thorac Surg. 2017 Mar 1;24(3):414-417. doi: 10.1093/icvts/ivw373.


Aspirin Suppresses Growth in PI3K-Mutant Breast Cancer by Activating AMPK and Inhibiting mTORC1 Signaling.

Henry WS, Laszewski T, Tsang T, Beca F, Beck AH, McAllister SS, Toker A.

Cancer Res. 2017 Feb 1;77(3):790-801. doi: 10.1158/0008-5472.CAN-16-2400. Epub 2016 Dec 9.

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