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Items: 1 to 50 of 325

1.

PI 3-Kinase Signaling: AKTing up inside the Cell.

Toker A, Dibble CC.

Mol Cell. 2018 Sep 20;71(6):875-876. doi: 10.1016/j.molcel.2018.09.006.

PMID:
30241602
2.

Regulatory T Cells in Ovarian Cancer Are Characterized by a Highly Activated Phenotype Distinct from that in Melanoma.

Toker A, Nguyen LT, Stone SC, Yang SYC, Katz SR, Shaw PA, Clarke BA, Ghazarian D, Al-Habeeb A, Easson A, Leong WL, McCready DR, Reedijk M, Guidos CJ, Pugh TJ, Bernardini MQ, Ohashi PS.

Clin Cancer Res. 2018 Jul 31. doi: 10.1158/1078-0432.CCR-18-0554. [Epub ahead of print]

PMID:
30065096
3.

Prognostic significance of carbonic anhydrase IX overexpression in stage III non-small cell lung cancer patients after neoadjuvant treatment.

Ibis K, Saglam S, Saglam EK, Firat P, Yilmazbayhan D, Toker A, Ozkan B, Hancer VS, Buyukdogan M, Disci R, Pilanci KN.

Pathol Res Pract. 2018 Sep;214(9):1291-1296. doi: 10.1016/j.prp.2018.07.010. Epub 2018 Jul 11.

PMID:
30029935
4.

Robotic resection of Stage III lung cancer: an international retrospective study.

Veronesi G, Park B, Cerfolio R, Dylewski M, Toker A, Fontaine JP, Hanna WC, Morenghi E, Novellis P, Velez-Cubian FO, Amaral MH, Dieci E, Alloisio M, Toloza EM.

Eur J Cardiothorac Surg. 2018 Nov 1;54(5):912-919. doi: 10.1093/ejcts/ezy166.

PMID:
29718155
5.

Skp2-dependent reactivation of AKT drives resistance to PI3K inhibitors.

Clement E, Inuzuka H, Nihira NT, Wei W, Toker A.

Sci Signal. 2018 Mar 13;11(521). pii: eaao3810. doi: 10.1126/scisignal.aao3810.

6.

Outcomes from the Delphi process of the Thoracic Robotic Curriculum Development Committee.

Veronesi G, Dorn P, Dunning J, Cardillo G, Schmid RA, Collins J, Baste JM, Limmer S, Shahin GMM, Egberts JH, Pardolesi A, Meacci E, Stamenkovic S, Casali G, Rueckert JC, Taurchini M, Santelmo N, Melfi F, Toker A.

Eur J Cardiothorac Surg. 2018 Jun 1;53(6):1173-1179. doi: 10.1093/ejcts/ezx466.

PMID:
29377988
7.

Salvage thoracic surgery in patients with lung cancer: potential indications and benefits.

Kaba E, Ozyurtkan MO, Ayalp K, Cosgun T, Alomari MR, Toker A.

J Cardiothorac Surg. 2018 Jan 22;13(1):13. doi: 10.1186/s13019-018-0693-x.

8.

Oxygen Uptake Efficiency Slope and Prediction of Post-operative Morbidity and Mortality in Patients with Lung Cancer.

Yakal S, Sofyalı S, Özkan B, Yıldız S, Toker A, Kasikcioglu E.

Lung. 2018 Apr;196(2):255-262. doi: 10.1007/s00408-018-0085-y. Epub 2018 Jan 18.

PMID:
29349536
9.

Serum levels of cortisol, dehydroepiandrosterone, and oxytocin in children with attention-deficit/hyperactivity disorder combined presentation with and without comorbid conduct disorder.

Işık Ü, Bilgiç A, Toker A, Kılınç I.

Psychiatry Res. 2018 Mar;261:212-219. doi: 10.1016/j.psychres.2017.12.076. Epub 2018 Jan 2.

PMID:
29324397
10.

Oncogenic PI3K promotes methionine dependency in breast cancer cells through the cystine-glutamate antiporter xCT.

Lien EC, Ghisolfi L, Geck RC, Asara JM, Toker A.

Sci Signal. 2017 Dec 19;10(510). pii: eaao6604. doi: 10.1126/scisignal.aao6604.

11.

Role of Surgery in the Treatment of Masaoka Stage IVa Thymoma.

Kaba E, Ozkan B, Erus S, Duman S, Cimenoglu B, Toker A.

Ann Thorac Cardiovasc Surg. 2018 Feb 20;24(1):6-12. doi: 10.5761/atcs.oa.17-00108. Epub 2017 Dec 8.

12.

Identifying and Targeting Sporadic Oncogenic Genetic Aberrations in Mouse Models of Triple-Negative Breast Cancer.

Liu H, Murphy CJ, Karreth FA, Emdal KB, White FM, Elemento O, Toker A, Wulf GM, Cantley LC.

Cancer Discov. 2018 Mar;8(3):354-369. doi: 10.1158/2159-8290.CD-17-0679. Epub 2017 Dec 4. Erratum in: Cancer Discov. 2018 Aug;8(8):1044.

PMID:
29203461
13.

Nodal upstaging: effects of instrumentation and three-dimensional view in clinical stage I lung cancer.

Toker A, Özyurtkan MO, Kaba E.

J Vis Surg. 2017 May 30;3:76. doi: 10.21037/jovs.2017.04.05. eCollection 2017. Review.

14.

Robotic thymectomy-a new approach for thymus.

Kaba E, Cosgun T, Ayalp K, Alomari MR, Toker A.

J Vis Surg. 2017 May 8;3:67. doi: 10.21037/jovs.2017.03.28. eCollection 2017. Review.

15.

What happens while learning robotic lobectomy for lung cancer?

Özyurtkan MO, Kaba E, Toker A.

J Vis Surg. 2017 Mar 10;3:27. doi: 10.21037/jovs.2017.02.02. eCollection 2017. Review.

16.

Technological innovation in video-assisted thoracic surgery.

Özyurtkan MO, Kaba E, Toker A.

J Vis Surg. 2017 Feb 15;3:20. doi: 10.21037/jovs.2017.01.03. eCollection 2017.

17.

Robotic lung resections: video-assisted thoracic surgery based approach.

Toker A, Kaba E, Ayalp K, Özyurtkan MO.

J Vis Surg. 2017 Feb 13;3:15. doi: 10.21037/jovs.2017.01.08. eCollection 2017. Review.

18.

Prompt Response to Prednisone Predicts Benign Course in MuSK-MG.

Gungor-Tuncer O, Yilmaz V, Toker A, Saruhan-Direskeneli G, Gulsen-Parman Y, Oflazer-Serdaroglu P, Deymeer F.

Eur Neurol. 2017;78(3-4):137-142. doi: 10.1159/000479228. Epub 2017 Jul 28.

PMID:
28768265
19.

Effects of Carvacrol on Survival, Mesenteric Blood Flow, Aortic Function and Multiple Organ Injury in a Murine Model of Polymicrobial Sepsis.

Ozer EK, Goktas MT, Toker A, Bariskaner H, Ugurluoglu C, Iskit AB.

Inflammation. 2017 Oct;40(5):1654-1663. doi: 10.1007/s10753-017-0605-6.

PMID:
28646428
20.

The Importance of Liver-Fatty Acid Binding Protein in Diagnosis of Liver Damage in Patients with Acute Hepatitis.

Cakir OO, Toker A, Ataseven H, Demir A, Polat H.

J Clin Diagn Res. 2017 Apr;11(4):OC17-OC21. doi: 10.7860/JCDR/2017/24958.9621. Epub 2017 Apr 1.

21.

Thymoquinone protects against the sepsis induced mortality, mesenteric hypoperfusion, aortic dysfunction and multiple organ damage in rats.

Ozer EK, Goktas MT, Toker A, Pehlivan S, Bariskaner H, Ugurluoglu C, Iskit AB.

Pharmacol Rep. 2017 Aug;69(4):683-690. doi: 10.1016/j.pharep.2017.02.021. Epub 2017 Mar 24.

PMID:
28549307
22.

Infliximab alleviates the mortality, mesenteric hypoperfusion, aortic dysfunction, and multiple organ damage in septic rats.

Ozer EK, Goktas MT, Kilinc I, Toker A, Bariskaner H, Ugurluoglu C, Iskit AB.

Can J Physiol Pharmacol. 2017 Jul;95(7):866-872. doi: 10.1139/cjpp-2016-0628. Epub 2017 Apr 29.

PMID:
28459157
23.

AKT/PKB Signaling: Navigating the Network.

Manning BD, Toker A.

Cell. 2017 Apr 20;169(3):381-405. doi: 10.1016/j.cell.2017.04.001. Review.

24.

Unique properties of thymic antigen-presenting cells promote epigenetic imprinting of alloantigen-specific regulatory T cells.

Garg G, Nikolouli E, Hardtke-Wolenski M, Toker A, Ohkura N, Beckstette M, Miyao T, Geffers R, Floess S, Gerdes N, Lutgens E, Osterloh A, Hori S, Sakaguchi S, Jaeckel E, Huehn J.

Oncotarget. 2017 May 30;8(22):35542-35557. doi: 10.18632/oncotarget.16221.

25.

A benchmarking project on the quality of previous guidelines about the management of malignant pleural effusion from the European Society of Thoracic Surgeons (ESTS) Pleural Diseases Working Group.

Bertolaccini L, Bedetti B, Brunelli A, Marinova K, Raveglia F, Rocco G, Shargall Y, Solli P, Varela G, Papagiannopoulos K, Kuzdzal J, Massard G, Ruffini E, Falcoz PE, Martinez-Barenys C, Opitz I, Batirel HF, Toker A, Scarci M; Members of the ESTS Pleural Disease Working Group.

Eur J Cardiothorac Surg. 2017 Aug 1;52(2):356-362. doi: 10.1093/ejcts/ezx089.

PMID:
28402401
26.

Cross-talk between the CK2 and AKT signaling pathways in cancer.

Ruzzene M, Bertacchini J, Toker A, Marmiroli S.

Adv Biol Regul. 2017 May;64:1-8. doi: 10.1016/j.jbior.2017.03.002. Epub 2017 Mar 28. Review.

PMID:
28373060
27.

PI3K signaling in cancer: beyond AKT.

Lien EC, Dibble CC, Toker A.

Curr Opin Cell Biol. 2017 Apr;45:62-71. doi: 10.1016/j.ceb.2017.02.007. Epub 2017 Mar 24. Review.

28.

Adaptive Reprogramming of De Novo Pyrimidine Synthesis Is a Metabolic Vulnerability in Triple-Negative Breast Cancer.

Brown KK, Spinelli JB, Asara JM, Toker A.

Cancer Discov. 2017 Apr;7(4):391-399. doi: 10.1158/2159-8290.CD-16-0611. Epub 2017 Mar 2. Erratum in: Cancer Discov. 2017 Jul;7(7):782.

29.

Pentraxin-3 is a PI3K signaling target that promotes stem cell-like traits in basal-like breast cancers.

Thomas C, Henry W, Cuiffo BG, Collmann AY, Marangoni E, Benhamo V, Bhasin MK, Fan C, Fuhrmann L, Baldwin AS, Perou C, Vincent-Salomon A, Toker A, Karnoub AE.

Sci Signal. 2017 Feb 21;10(467). pii: eaah4674. doi: 10.1126/scisignal.aah4674.

30.

The SCFβ-TRCP E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis.

Shimizu K, Fukushima H, Ogura K, Lien EC, Nihira NT, Zhang J, North BJ, Guo A, Nagashima K, Nakagawa T, Hoshikawa S, Watahiki A, Okabe K, Yamada A, Toker A, Asara JM, Fukumoto S, Nakayama KI, Nakayama K, Inuzuka H, Wei W.

Sci Signal. 2017 Jan 3;10(460). pii: eaah4117. doi: 10.1126/scisignal.aah4117.

31.

Current practices in the management of malignant pleural effusions: a survey among members of the European Society of Thoracic Surgeons.

Scarci M, Caruana E, Bertolaccini L, Bedetti B, Brunelli A, Varela G, Papagiannopoulos K, Kuzdzal J, Massard G, Ruffini E, Falcoz PE, Opitz I, Batirel H, Toker A, Rocco G; ESTS Malignant Pleural Effusion Working Group.

Interact Cardiovasc Thorac Surg. 2017 Mar 1;24(3):414-417. doi: 10.1093/icvts/ivw373.

PMID:
28040756
32.

Aspirin Suppresses Growth in PI3K-Mutant Breast Cancer by Activating AMPK and Inhibiting mTORC1 Signaling.

Henry WS, Laszewski T, Tsang T, Beca F, Beck AH, McAllister SS, Toker A.

Cancer Res. 2017 Feb 1;77(3):790-801. doi: 10.1158/0008-5472.CAN-16-2400. Epub 2016 Dec 9.

33.

Suppression of bromodomain-containing protein 4 by shRNA: A new approach for cancer treatment.

Kaya T, Kahraman B, Bazarov N, Toker AS, Celik A, Cigdem S, Gunduz E.

Clin Invest Med. 2016 Dec 1;39(6):27493.

PMID:
27917784
34.

Report on First International Workshop on Robotic Surgery in Thoracic Oncology.

Veronesi G, Cerfolio R, Cingolani R, Rueckert JC, Soler L, Toker A, Cariboni U, Bottoni E, Fumagalli U, Melfi F, Milli C, Novellis P, Voulaz E, Alloisio M.

Front Oncol. 2016 Oct 24;6:214. eCollection 2016.

35.

Lymph Node Dissection in Surgery for Lung Cancer: Comparison of Open vs. Video-Assisted vs. Robotic-Assisted Approaches.

Toker A, Özyurtkan MO, Demirhan Ö, Ayalp K, Kaba E, Uyumaz E.

Ann Thorac Cardiovasc Surg. 2016 Oct 20;22(5):284-290. Epub 2016 Aug 10.

36.

LINC00520 is induced by Src, STAT3, and PI3K and plays a functional role in breast cancer.

Henry WS, Hendrickson DG, Beca F, Glass B, Lindahl-Allen M, He L, Ji Z, Struhl K, Beck AH, Rinn JL, Toker A.

Oncotarget. 2016 Dec 13;7(50):81981-81994. doi: 10.18632/oncotarget.11962.

37.

Total antioxidant, total oxidant and serum paraoxonase levels according to lipid administration method in parenterally fed premature infants.

Konak M, Tarakci N, Altunhan H, Annagür A, Toker A, Örs R.

J Matern Fetal Neonatal Med. 2017 Jul;30(14):1734-1738. doi: 10.1080/14767058.2016.1224231. Epub 2016 Sep 1.

PMID:
27583439
38.

pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner.

Guo J, Chakraborty AA, Liu P, Gan W, Zheng X, Inuzuka H, Wang B, Zhang J, Zhang L, Yuan M, Novak J, Cheng JQ, Toker A, Signoretti S, Zhang Q, Asara JM, Kaelin WG Jr, Wei W.

Science. 2016 Aug 26;353(6302):929-32. doi: 10.1126/science.aad5755.

39.

Serum brain-derived neurotrophic factor, glial-derived neurotrophic factor, nerve growth factor, and neurotrophin-3 levels in children with attention-deficit/hyperactivity disorder.

Bilgiç A, Toker A, Işık Ü, Kılınç İ.

Eur Child Adolesc Psychiatry. 2017 Mar;26(3):355-363. doi: 10.1007/s00787-016-0898-2. Epub 2016 Aug 25.

PMID:
27561780
40.

The effect of melatonin and vitamin C treatment on the experimentally induced tympanosclerosis: study in rats.

Koc S, Kıyıcı H, Toker A, Soyalıç H, Aslan H, Kesici H, Karaca ZI.

Braz J Otorhinolaryngol. 2017 Sep - Oct;83(5):541-545. doi: 10.1016/j.bjorl.2016.06.008. Epub 2016 Jul 20.

41.

Concomitant etoposide and cisplatin provided improved survival compared with docetaxel and cisplatin in patients with locally advanced non-small cell lung cancer treated with chemoradiotherapy.

Sen F, Tambas M, Ozkaya K, Guveli ME, Ciftci R, Ozkan B, Oral EN, Saglam EK, Saip P, Toker A, Demir A, Firat P, Aydiner A, Eralp Y.

Medicine (Baltimore). 2016 Jul;95(30):e4280. doi: 10.1097/MD.0000000000004280.

42.

The LDL/HDL ratio and atherosclerosis in ankylosing spondylitis.

Kucuk A, Uğur Uslu A, Icli A, Cure E, Arslan S, Turkmen K, Toker A, Kayrak M.

Z Rheumatol. 2017 Feb;76(1):58-63. doi: 10.1007/s00393-016-0092-4.

PMID:
27312464
43.

Editorial on "Postoperative survival for patients with thymoma complicating myasthenia gravis-preliminary retrospective results of the ChART database".

Toker A, Ozkan B.

J Thorac Dis. 2016 Jun;8(6):1048-9. doi: 10.21037/jtd.2016.04.53. No abstract available.

44.

Exploratory study to evaluate plasma vasopressin and apelin-13 levels in children with attention-deficit hyperactivity disorder.

Bilgiç A, Toker A, Uysal S.

Psychiatry Clin Neurosci. 2016 Oct;70(10):442-447. doi: 10.1111/pcn.12415. Epub 2016 Aug 2.

45.

Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt.

Zhang J, Xu K, Liu P, Geng Y, Wang B, Gan W, Guo J, Wu F, Chin YR, Berrios C, Lien EC, Toker A, DeCaprio JA, Sicinski P, Wei W.

Mol Cell. 2016 Jun 16;62(6):929-942. doi: 10.1016/j.molcel.2016.04.023. Epub 2016 May 26.

46.

Catastrophes during video-assisted thoracoscopic thymus surgery for myasthenia gravis.

Özkan B, Toker A.

Interact Cardiovasc Thorac Surg. 2016 Sep;23(3):450-3. doi: 10.1093/icvts/ivw144. Epub 2016 May 19.

PMID:
27199379
47.

Glutathione biosynthesis is a metabolic vulnerability in PI(3)K/Akt-driven breast cancer.

Lien EC, Lyssiotis CA, Juvekar A, Hu H, Asara JM, Cantley LC, Toker A.

Nat Cell Biol. 2016 May;18(5):572-8. doi: 10.1038/ncb3341. Epub 2016 Apr 18.

48.

Sleeve resection for bronchial carcinoid tumour in two children under six years old.

Erginel B, Ozkan B, Gun Soysal F, Celik A, Salman T, Toker A.

World J Surg Oncol. 2016 Apr 14;14:108. doi: 10.1186/s12957-016-0870-0.

49.

The relation between ischemia modified albumin levels and carotid intima media thickness in patients with rheumatoid arthritis.

Uslu AU, Kucuk A, Balta S, Ozturk C, Arslan S, Tekin L, Kucuksen S, Toker A, Kayrak M.

Int J Rheum Dis. 2016 Mar 30. doi: 10.1111/1756-185X.12851. [Epub ahead of print]

PMID:
27028097
50.

Oncogenic AKT1(E17K) mutation induces mammary hyperplasia but prevents HER2-driven tumorigenesis.

Mancini ML, Lien EC, Toker A.

Oncotarget. 2016 Apr 5;7(14):17301-13. doi: 10.18632/oncotarget.8191.

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