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Items: 25

1.

A balancing act: PHLPP2 fine tunes AKT activity and MYC stability in prostate cancer.

Toivanen R, Furic L.

J Cell Biol. 2019 Jun 3;218(6):1771-1772. doi: 10.1083/jcb.201904119. Epub 2019 May 15.

PMID:
31145683
2.

Patient-derived Models of Abiraterone- and Enzalutamide-resistant Prostate Cancer Reveal Sensitivity to Ribosome-directed Therapy.

Lawrence MG, Obinata D, Sandhu S, Selth LA, Wong SQ, Porter LH, Lister N, Pook D, Pezaro CJ, Goode DL, Rebello RJ, Clark AK, Papargiris M, Van Gramberg J, Hanson AR, Banks P, Wang H, Niranjan B, Keerthikumar S, Hedwards S, Huglo A, Yang R, Henzler C, Li Y, Lopez-Campos F, Castro E, Toivanen R, Azad A, Bolton D, Goad J, Grummet J, Harewood L, Kourambas J, Lawrentschuk N, Moon D, Murphy DG, Sengupta S, Snow R, Thorne H, Mitchell C, Pedersen J, Clouston D, Norden S, Ryan A, Dehm SM, Tilley WD, Pearson RB, Hannan RD, Frydenberg M, Furic L, Taylor RA, Risbridger GP.

Eur Urol. 2018 Nov;74(5):562-572. doi: 10.1016/j.eururo.2018.06.020. Epub 2018 Jul 23.

PMID:
30049486
3.

Preclinical Models of Prostate Cancer: Patient-Derived Xenografts, Organoids, and Other Explant Models.

Risbridger GP, Toivanen R, Taylor RA.

Cold Spring Harb Perspect Med. 2018 Aug 1;8(8). pii: a030536. doi: 10.1101/cshperspect.a030536. Review.

PMID:
29311126
4.

Partners of nulliparous women with severe fear of childbirth: A longitudinal study of psychological well-being.

Ryding EL, Read S, Rouhe H, Halmesmäki E, Salmela-Aro K, Toivanen R, Tokola M, Saisto T.

Birth. 2018 Mar;45(1):88-93. doi: 10.1111/birt.12309. Epub 2017 Sep 11.

PMID:
28892237
5.

Transdifferentiation as a Mechanism of Treatment Resistance in a Mouse Model of Castration-Resistant Prostate Cancer.

Zou M, Toivanen R, Mitrofanova A, Floch N, Hayati S, Sun Y, Le Magnen C, Chester D, Mostaghel EA, Califano A, Rubin MA, Shen MM, Abate-Shen C.

Cancer Discov. 2017 Jul;7(7):736-749. doi: 10.1158/2159-8290.CD-16-1174. Epub 2017 Apr 14.

6.

Prostate organogenesis: tissue induction, hormonal regulation and cell type specification.

Toivanen R, Shen MM.

Development. 2017 Apr 15;144(8):1382-1398. doi: 10.1242/dev.148270. Review.

7.

Basal Progenitors Contribute to Repair of the Prostate Epithelium Following Induced Luminal Anoikis.

Toivanen R, Mohan A, Shen MM.

Stem Cell Reports. 2016 May 10;6(5):660-667. doi: 10.1016/j.stemcr.2016.03.007. Epub 2016 Apr 21.

8.

Erratum: Stromal androgen receptor regulates the composition of the microenvironment to influence prostate cancer outcome.

Leach DA, Need EF, Toivanen R, Trotta AP, Palethorpe HM, Tamblyn DJ, Kopsaftis T, England GM, Smith E, Drew PA, Pinnock CB, Lee P, Holst J, Risbridger GP, Chopra S, DeFranco DB, Taylor RA, Buchanan G.

Oncotarget. 2015 Nov 3;6(34):36923. doi: 10.18632/oncotarget.6263. No abstract available.

9.

Stromal androgen receptor regulates the composition of the microenvironment to influence prostate cancer outcome.

Leach DA, Need EF, Toivanen R, Trotta AP, Palethorpe HM, Tamblyn DJ, Kopsaftis T, England GM, Smith E, Drew PA, Pinnock CB, Lee P, Holst J, Risbridger GP, Chopra S, DeFranco DB, Taylor RA, Buchanan G.

Oncotarget. 2015 Jun 30;6(18):16135-50. Erratum in: Oncotarget. 2015 Nov 3;6(34):36923. Palenthorpe, Helen M [Corrected to Palethorpe, Helen M].

10.

Life satisfaction, general well-being and costs of treatment for severe fear of childbirth in nulliparous women by psychoeducative group or conventional care attendance.

Rouhe H, Salmela-Aro K, Toivanen R, Tokola M, Halmesmäki E, Saisto T.

Acta Obstet Gynecol Scand. 2015 May;94(5):527-33. doi: 10.1111/aogs.12594. Epub 2015 Mar 4.

PMID:
25627259
11.

Group psychoeducation with relaxation for severe fear of childbirth improves maternal adjustment and childbirth experience--a randomised controlled trial.

Rouhe H, Salmela-Aro K, Toivanen R, Tokola M, Halmesmäki E, Ryding EL, Saisto T.

J Psychosom Obstet Gynaecol. 2015;36(1):1-9. doi: 10.3109/0167482X.2014.980722. Epub 2014 Nov 24.

PMID:
25417935
12.

Single luminal epithelial progenitors can generate prostate organoids in culture.

Chua CW, Shibata M, Lei M, Toivanen R, Barlow LJ, Bergren SK, Badani KK, McKiernan JM, Benson MC, Hibshoosh H, Shen MM.

Nat Cell Biol. 2014 Oct;16(10):951-61, 1-4. doi: 10.1038/ncb3047. Epub 2014 Sep 21.

13.

Luminal cells are favored as the cell of origin for prostate cancer.

Wang ZA, Toivanen R, Bergren SK, Chambon P, Shen MM.

Cell Rep. 2014 Sep 11;8(5):1339-46. doi: 10.1016/j.celrep.2014.08.002. Epub 2014 Aug 28.

14.

Patient-derived xenografts reveal that intraductal carcinoma of the prostate is a prominent pathology in BRCA2 mutation carriers with prostate cancer and correlates with poor prognosis.

Risbridger GP, Taylor RA, Clouston D, Sliwinski A, Thorne H, Hunter S, Li J, Mitchell G, Murphy D, Frydenberg M, Pook D, Pedersen J, Toivanen R, Wang H, Papargiris M, Lawrence MG, Bolton DM.

Eur Urol. 2015 Mar;67(3):496-503. doi: 10.1016/j.eururo.2014.08.007. Epub 2014 Aug 22.

PMID:
25154392
15.

A preclinical xenograft model identifies castration-tolerant cancer-repopulating cells in localized prostate tumors.

Toivanen R, Frydenberg M, Murphy D, Pedersen J, Ryan A, Pook D, Berman DM; Australian Prostate Cancer BioResource, Taylor RA, Risbridger GP.

Sci Transl Med. 2013 May 29;5(187):187ra71. doi: 10.1126/scitranslmed.3005688.

16.

A preclinical xenograft model of prostate cancer using human tumors.

Lawrence MG, Taylor RA, Toivanen R, Pedersen J, Norden S, Pook DW, Frydenberg M; Australian Prostate Cancer BioResource, Papargiris MM, Niranjan B, Richards MG, Wang H, Collins AT, Maitland NJ, Risbridger GP.

Nat Protoc. 2013 May;8(5):836-48. doi: 10.1038/nprot.2013.043. Epub 2013 Apr 4.

PMID:
23558784
17.

Obstetric outcome after intervention for severe fear of childbirth in nulliparous women - randomised trial.

Rouhe H, Salmela-Aro K, Toivanen R, Tokola M, Halmesmäki E, Saisto T.

BJOG. 2013 Jan;120(1):75-84. doi: 10.1111/1471-0528.12011. Epub 2012 Nov 2.

18.

Human epithelial basal cells are cells of origin of prostate cancer, independent of CD133 status.

Taylor RA, Toivanen R, Frydenberg M, Pedersen J, Harewood L; Australian Prostate Cancer Bioresource, Collins AT, Maitland NJ, Risbridger GP.

Stem Cells. 2012 Jun;30(6):1087-96. doi: 10.1002/stem.1094. Erratum in: Stem Cells. 2012 Aug;30(8):1786.

19.

Breaking through a roadblock in prostate cancer research: an update on human model systems.

Toivanen R, Taylor RA, Pook DW, Ellem SJ, Risbridger GP.

J Steroid Biochem Mol Biol. 2012 Sep;131(3-5):122-31. doi: 10.1016/j.jsbmb.2012.01.005. Epub 2012 Feb 8. Review.

PMID:
22342674
20.

Promoting positive motherhood among nulliparous pregnant women with an intense fear of childbirth: RCT intervention.

Salmela-Aro K, Read S, Rouhe H, Halmesmäki E, Toivanen RM, Tokola MI, Saisto T.

J Health Psychol. 2012 May;17(4):520-34. doi: 10.1177/1359105311421050. Epub 2011 Sep 29.

PMID:
21963681
21.

Brief report: a bioassay to identify primary human prostate cancer repopulating cells.

Toivanen R, Berman DM, Wang H, Pedersen J, Frydenberg M, Meeker AK, Ellem SJ, Risbridger GP, Taylor RA.

Stem Cells. 2011 Aug;29(8):1310-4. doi: 10.1002/stem.668.

22.

Stem cells in prostate cancer: treating the root of the problem.

Taylor RA, Toivanen R, Risbridger GP.

Endocr Relat Cancer. 2010 Sep 23;17(4):R273-85. doi: 10.1677/ERC-10-0145. Print 2010 Dec. Review.

PMID:
20660571
23.

Estrogen receptor-beta activated apoptosis in benign hyperplasia and cancer of the prostate is androgen independent and TNFalpha mediated.

McPherson SJ, Hussain S, Balanathan P, Hedwards SL, Niranjan B, Grant M, Chandrasiri UP, Toivanen R, Wang Y, Taylor RA, Risbridger GP.

Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3123-8. doi: 10.1073/pnas.0905524107. Epub 2010 Feb 1.

24.

Therapeutic group psychoeducation and relaxation in treating fear of childbirth.

Saisto T, Toivanen R, Salmela-Aro K, Halmesmäki E.

Acta Obstet Gynecol Scand. 2006;85(11):1315-9.

PMID:
17091410
25.

[Population study of antibodies to some potential pathogens of spondyloarthopathies: the study of the Chukotka population].

Guseva IA, Uksila J, Erdes Sh, Toivanen R, Benevolenskaia LI.

Klin Med (Mosk). 1999;77(5):27-31. Russian.

PMID:
10394783

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