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Items: 1 to 50 of 357

1.

Axon Guidance-Related Factor FLRT3 Regulates VEGF-Signaling and Endothelial Cell Function.

Jauhiainen S, Laakkonen JP, Ketola K, Toivanen PI, Nieminen T, Ninchoji T, Levonen AL, Kaikkonen MU, Ylä-Herttuala S.

Front Physiol. 2019 Mar 12;10:224. doi: 10.3389/fphys.2019.00224. eCollection 2019.

2.

Adenoviral intramyocardial VEGF-DΔNΔC gene transfer increases myocardial perfusion reserve in refractory angina patients: a phase I/IIa study with 1-year follow-up.

Hartikainen J, Hassinen I, Hedman A, Kivelä A, Saraste A, Knuuti J, Husso M, Mussalo H, Hedman M, Rissanen TT, Toivanen P, Heikura T, Witztum JL, Tsimikas S, Ylä-Herttuala S.

Eur Heart J. 2017 Sep 1;38(33):2547-2555. doi: 10.1093/eurheartj/ehx352. Erratum in: Eur Heart J. 2018 May 7;39(18):1652.

3.

Snake venom VEGF Vammin induces a highly efficient angiogenic response in skeletal muscle via VEGFR-2/NRP specific signaling.

Toivanen PI, Nieminen T, Laakkonen JP, Heikura T, Kaikkonen MU, Ylä-Herttuala S.

Sci Rep. 2017 Jul 17;7(1):5525. doi: 10.1038/s41598-017-05876-y.

4.

Differential regulation of angiogenic cellular processes and claudin-5 by histamine and VEGF via PI3K-signaling, transcription factor SNAI2 and interleukin-8.

Laakkonen JP, Lappalainen JP, Theelen TL, Toivanen PI, Nieminen T, Jauhiainen S, Kaikkonen MU, Sluimer JC, Ylä-Herttuala S.

Angiogenesis. 2017 Feb;20(1):109-124. doi: 10.1007/s10456-016-9532-7. Epub 2016 Nov 21.

PMID:
27873103
5.

Slit2 modifies VEGF-induced angiogenic responses in rabbit skeletal muscle via reduced eNOS activity.

Nieminen T, Toivanen PI, Laakkonen JP, Heikura T, Kaikkonen MU, Airenne KJ, Ylä-Herttuala S.

Cardiovasc Res. 2015 Jul 15;107(2):267-76. doi: 10.1093/cvr/cvv161. Epub 2015 May 22.

PMID:
26002231
6.

The impact of the receptor binding profiles of the vascular endothelial growth factors on their angiogenic features.

Nieminen T, Toivanen PI, Rintanen N, Heikura T, Jauhiainen S, Airenne KJ, Alitalo K, Marjomäki V, Ylä-Herttuala S.

Biochim Biophys Acta. 2014 Jan;1840(1):454-63. doi: 10.1016/j.bbagen.2013.10.005. Epub 2013 Oct 8.

PMID:
24112971
7.

Preclinical safety, toxicology, and biodistribution study of adenoviral gene therapy with sVEGFR-2 and sVEGFR-3 combined with chemotherapy for ovarian cancer.

Tuppurainen L, Sallinen H, Kokki E, Koponen J, Anttila M, Pulkkinen K, Heikura T, Toivanen P, Hämäläinen K, Kosma VM, Heinonen S, Alitalo K, Ylä-Herttuala S.

Hum Gene Ther Clin Dev. 2013 Mar;24(1):29-37. doi: 10.1089/humc.2013.006. Epub 2013 Apr 3.

PMID:
23692381
8.

Vascular endothelial growth factor (VEGF)-D stimulates VEGF-A, stanniocalcin-1, and neuropilin-2 and has potent angiogenic effects.

Jauhiainen S, Häkkinen SK, Toivanen PI, Heinonen SE, Jyrkkänen HK, Kansanen E, Leinonen H, Levonen AL, Ylä-Herttuala S.

Arterioscler Thromb Vasc Biol. 2011 Jul;31(7):1617-24. doi: 10.1161/ATVBAHA.111.225961. Epub 2011 Apr 7.

PMID:
21474827
9.

A laboratory-scale device for the straightforward production of uniform, small sized cell microcapsules with long-term cell viability.

Kontturi LS, Yliperttula M, Toivanen P, Määttä A, Määttä AM, Urtti A.

J Control Release. 2011 Jun 30;152(3):376-81. doi: 10.1016/j.jconrel.2011.03.005. Epub 2011 Mar 22.

PMID:
21397645
10.

Structural determinants of vascular endothelial growth factor-D receptor binding and specificity.

Leppänen VM, Jeltsch M, Anisimov A, Tvorogov D, Aho K, Kalkkinen N, Toivanen P, Ylä-Herttuala S, Ballmer-Hofer K, Alitalo K.

Blood. 2011 Feb 3;117(5):1507-15. doi: 10.1182/blood-2010-08-301549. Epub 2010 Dec 8.

PMID:
21148085
11.

Invited article: Electric solar wind sail: toward test missions.

Janhunen P, Toivanen PK, Polkko J, Merikallio S, Salminen P, Haeggström E, Seppänen H, Kurppa R, Ukkonen J, Kiprich S, Thornell G, Kratz H, Richter L, Krömer O, Rosta R, Noorma M, Envall J, Lätt S, Mengali G, Quarta AA, Koivisto H, Tarvainen O, Kalvas T, Kauppinen J, Nuottajärvi A, Obraztsov A.

Rev Sci Instrum. 2010 Nov;81(11):111301. doi: 10.1063/1.3514548.

PMID:
21133454
12.

A 96-well format for a high-throughput baculovirus generation, fast titering and recombinant protein production in insect and mammalian cells.

Kärkkäinen HR, Lesch HP, Määttä AI, Toivanen PI, Mähönen AJ, Roschier MM, Airenne KJ, Laitinen OH, Ylä-Herttuala S.

BMC Res Notes. 2009 Apr 23;2:63. doi: 10.1186/1756-0500-2-63.

13.

Novel vascular endothelial growth factor D variants with increased biological activity.

Toivanen PI, Nieminen T, Viitanen L, Alitalo A, Roschier M, Jauhiainen S, Markkanen JE, Laitinen OH, Airenne TT, Salminen TA, Johnson MS, Airenne KJ, Ylä-Herttuala S.

J Biol Chem. 2009 Jun 5;284(23):16037-48. doi: 10.1074/jbc.M109.001123. Epub 2009 Apr 14.

14.

Antiangiogenic gene therapy with soluble VEGFR-1, -2, and -3 reduces the growth of solid human ovarian carcinoma in mice.

Sallinen H, Anttila M, Narvainen J, Koponen J, Hamalainen K, Kholova I, Heikura T, Toivanen P, Kosma VM, Heinonen S, Alitalo K, Yla-Herttuala S.

Mol Ther. 2009 Feb;17(2):278-84. doi: 10.1038/mt.2008.258. Epub 2008 Dec 2.

15.

Fecal microbiota in early rheumatoid arthritis.

Vaahtovuo J, Munukka E, Korkeamäki M, Luukkainen R, Toivanen P.

J Rheumatol. 2008 Aug;35(8):1500-5. Epub 2008 Jun 1.

PMID:
18528968
16.

Comparison of a Multidose Powder Inhaler Containing Beclomethasone Dipropionate (BDP) with a BDP Metered Dose Inhaler with Spacer in the Treatment of Asthmatic Patients.

Poukkula A, Alanko K, Kilpiö K, Knuuttila A, Koskinen S, Laitinen J, Lehtonen K, Liippo K, Lindqvist A, Lähelmä S, Paananen M, Ruotsalainen EM, Salomaa ER, Silvasti M, Suuronen U, Toivanen P, Vilkka V.

Clin Drug Investig. 1998;16(2):101-10.

PMID:
18370527
17.

Method for characterization of filter radiometers.

Toivanen P, Manoochehri F, Kärhä P, Ikonen E, Lassila A.

Appl Opt. 1999 Mar 20;38(9):1709-13.

PMID:
18305795
18.

Development of a detector-based absolute spectral irradiance scale in the 380-900-nm spectral range.

Kärhä P, Toivanen P, Manoochehri F, Ikonen E.

Appl Opt. 1997 Dec 1;36(34):8909-18.

PMID:
18264443
19.

Social and early-life determinants of overweight and obesity in 18-year-old Swedish men.

Koupil I, Toivanen P.

Int J Obes (Lond). 2008 Jan;32(1):73-81. Epub 2007 Jul 31.

PMID:
17667914
20.

Which viruses should we look for in a recent onset polyarthritis.

Toivanen A, Toivanen P.

Acta Reumatol Port. 2006 Jan-Mar;31(1):39-47. Review.

21.

Quantification of bacteria in human feces using 16S rRNA-hybridization, DNA-staining and flow cytometry.

Vaahtovuo J, Korkeamäki M, Munukka E, Viljanen MK, Toivanen P.

J Microbiol Methods. 2005 Dec;63(3):276-86. Epub 2005 Jun 1.

PMID:
15935498
22.

A multipurpose vector system for the screening of libraries in bacteria, insect and mammalian cells and expression in vivo.

Laitinen OH, Airenne KJ, Hytönen VP, Peltomaa E, Mähönen AJ, Wirth T, Lind MM, Mäkelä KA, Toivanen PI, Schenkwein D, Heikura T, Nordlund HR, Kulomaa MS, Ylä-Herttuala S.

Nucleic Acids Res. 2005 Feb 24;33(4):e42.

23.

Reactive arthritis.

Toivanen A, Toivanen P.

Best Pract Res Clin Rheumatol. 2004 Oct;18(5):689-703. Review.

PMID:
15454127
24.

Preventive and therapeutic effects of sugar cane extract on cyclophosphamide-induced immunosuppression in chickens.

El-Abasy M, Motobu M, Nakamura K, Koge K, Onodera T, Vainio O, Toivanen P, Hirota Y.

Int Immunopharmacol. 2004 Aug;4(8):983-90. Erratum in: Int Immunopharmacol. 2004 Nov;4(12):1565-8.

PMID:
15222973
25.

Role of peptidoglycan subtypes in the pathogenesis of bacterial cell wall arthritis.

Simelyte E, Rimpiläinen M, Zhang X, Toivanen P.

Ann Rheum Dis. 2003 Oct;62(10):976-82.

26.
27.
28.

Bacterial composition of murine fecal microflora is indigenous and genetically guided.

Vaahtovuo J, Toivanen P, Eerola E.

FEMS Microbiol Ecol. 2003 May 1;44(1):131-6. doi: 10.1016/S0168-6496(02)00460-9.

29.

Effects of 6-hydroxydopamine on the development of the immune system in chickens.

Motobu M, El-Abasy M, Na KJ, Vainio O, Toivanen P, Hirota Y.

J Vet Med Sci. 2003 Jan;65(1):35-42.

PMID:
12576702
30.

Comparison of two budesonide powder inhalers, Easyhaler and Turbuhaler, in steroid-naïve asthmatic patients.

Schweisfurth H, Malinen A, Koskela T, Toivanen P, Ranki-Pesonen M; German Study Group.

Respir Med. 2002 Aug;96(8):599-606.

31.

Suppression of antigen-specific lymphocyte proliferation by Gram-positive bacterial cell walls.

Chen T, Toivanen P, Vainio O.

APMIS. 2002 Jun;110(6):490-8.

PMID:
12193210
32.

A vegan diet changes the intestinal flora.

Toivanen P, Eerola E.

Rheumatology (Oxford). 2002 Aug;41(8):950-1. No abstract available.

PMID:
12154219
33.

Mononuclear cell response to enterobacteria and Gram-positive cell walls of normal intestinal microbiota in early rheumatoid arthritis and other inflammatory arthritides.

Chen T, Rimpiläinen M, Luukkainen R, Möttönen T, Yli-Kerttula U, Saario R, Toivanen P.

Clin Exp Rheumatol. 2002 Mar-Apr;20(2):193-200.

PMID:
12051398
34.
35.

Study of murine faecal microflora by cellular fatty acid analysis; effect of age and mouse strain.

Vaahtovuo J, Toivanen P, Eerola E.

Antonie Van Leeuwenhoek. 2001 Oct;80(1):35-42.

PMID:
11761365
36.

Assessment of the systemic effects of budesonide inhaled from Easyhaler and from Turbuhaler in healthy male volunteers.

Hämäläinen KM, Granander M, Toivanen P, Malinen A.

Respir Med. 2001 Nov;95(11):863-9.

37.

Failure to verify H-ras mutations in arthritic synovium: comment on the article by Roivainen et al.

Roivainen A, Zhu F, Sipola E, Yli-Jama T, Toivanen P.

Arthritis Rheum. 2001 Nov;44(11):2705. No abstract available.

38.

Use of a peptide based enzyme immunoassay in diagnosis of Chlamydia trachomatis triggered reactive arthritis.

Nikkari S, Puolakkainen M, Närvänen A, Aakre O, Toivanen P, Leirisalo-Repo M.

J Rheumatol. 2001 Nov;28(11):2487-93.

PMID:
11708423
39.

Enzyme degradation and proinflammatory activity in arthritogenic and nonarthritogenic Eubacterium aerofaciens cell walls.

Zhang X, Rimpiläinen M, Simelyte E, Toivanen P.

Infect Immun. 2001 Dec;69(12):7277-84.

40.

Reactive arthritis.

Toivanen A, Toivanen P.

Isr Med Assoc J. 2001 Sep;3(9):681-5. Review.

41.

Experimental chronic arthritis and granulomatous inflammation induced by bifidobacterium cell walls.

Zhang X, Rimpiläinen M, Hoffmann B, Simelyte E, Aho H, Toivanen P.

Scand J Immunol. 2001 Jul-Aug;54(1-2):171-9.

42.

From reactive arthritis to rheumatoid arthritis.

Toivanen P.

J Autoimmun. 2001 May;16(3):369-71. Review.

PMID:
11334506
43.

Influence of major histocompatibility complex on bacterial composition of fecal flora.

Toivanen P, Vaahtovuo J, Eerola E.

Infect Immun. 2001 Apr;69(4):2372-7.

44.

Assessment of the systemic effects of beclomethasone dipropionate inhaled via Easyhaler or via Diskhaler in healthy male volunteers.

Hämäläinen KM, Malinen A, Granander M, Toivanen P, Silvasti M.

Eur J Clin Pharmacol. 2000 Dec;56(9-10):625-9.

PMID:
11214767
45.

Bacterial PCR in the diagnosis of joint infection.

Jalava J, Skurnik M, Toivanen A, Toivanen P, Eerola E.

Ann Rheum Dis. 2001 Mar;60(3):287-9.

46.

Characterisation of Eubacterium cell wall: peptidoglycan structure determines arthritogenicity.

Zhang X, Rimpiläinen M, Simelyte E, Toivanen P.

Ann Rheum Dis. 2001 Mar;60(3):269-74.

47.

Cytokine production in arthritis susceptible and resistant rats: a study with arthritogenic and non-arthritogenic Lactobacillus cell walls.

Simelyte E, Isomäki P, Rimpiläinen M, Zhang X, Toivanen P.

Scand J Immunol. 2001 Feb;53(2):132-8.

48.

BPI-ANCA is found in reactive arthritis caused by Yersinia and Salmonella infection and recognise exclusively the C-terminal part of the BPI molecule.

Schultz H, Csernok E, Nikkari S, Toivanen P, Toivanen A, Gross WL.

Scand J Rheumatol. 2000;29(4):226-31.

PMID:
11028843
49.

Reactive arthritis.

Toivanen A, Toivanen P.

Curr Opin Rheumatol. 2000 Jul;12(4):300-5. Review.

PMID:
10910183
50.

Interleukin-15 up-regulates the expression of CD154 on synovial fluid T cells.

Möttönen M, Isomäki P, Luukkainen R, Toivanen P, Punnonen J, Lassila O.

Immunology. 2000 Jun;100(2):238-44.

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