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Items: 1 to 50 of 118

1.

Serum Carcinoembryonic Antigen Levels Before the First Curative Hepatectomy for Metastatic Colorectal Cancer Is a Predictor of Recurrence.

Kawahara H, Yoshida S, Tohyama Y, Yanagisawa S, Misawa T, Yanaga K.

Anticancer Res. 2018 Sep;38(9):5351-5355. doi: 10.21873/anticanres.12863.

PMID:
30194188
2.

KIF20A, highly expressed in immature hematopoietic cells, supports the growth of HL60 cell line.

Morita H, Matsuoka A, Kida JI, Tabata H, Tohyama K, Tohyama Y.

Int J Hematol. 2018 Dec;108(6):607-614. doi: 10.1007/s12185-018-2527-y. Epub 2018 Sep 4.

PMID:
30182171
3.

An MDS-derived cell line and a series of its sublines serve as an in vitro model for the leukemic evolution of MDS.

Kida JI, Tsujioka T, Suemori SI, Okamoto S, Sakakibara K, Takahata T, Yamauchi T, Kitanaka A, Tohyama Y, Tohyama K.

Leukemia. 2018 Aug;32(8):1846-1850. doi: 10.1038/s41375-018-0189-7. Epub 2018 Jun 28. No abstract available.

PMID:
29955132
4.

Glycosaminoglycan Binding and Non-Endocytic Membrane Translocation of Cell-Permeable Octaarginine Monitored by Real-Time In-Cell NMR Spectroscopy.

Takechi-Haraya Y, Aki K, Tohyama Y, Harano Y, Kawakami T, Saito H, Okamura E.

Pharmaceuticals (Basel). 2017 Apr 15;10(2). pii: E42. doi: 10.3390/ph10020042.

5.

Control of the reversibility during boronic ester formation: application to the construction of ferrocene dimers and trimers.

Ono K, Tohyama Y, Uchikura T, Kikuchi Y, Fujii K, Uekusa H, Iwasawa N.

Dalton Trans. 2017 Feb 14;46(7):2370-2376. doi: 10.1039/c6dt04845e.

PMID:
28139793
6.

Withaferin A suppresses the growth of myelodysplasia and leukemia cell lines by inhibiting cell cycle progression.

Okamoto S, Tsujioka T, Suemori S, Kida J, Kondo T, Tohyama Y, Tohyama K.

Cancer Sci. 2016 Sep;107(9):1302-14. doi: 10.1111/cas.12988. Epub 2016 Jul 28.

7.

Five-aza-2'-deoxycytidine-induced hypomethylation of cholesterol 25-hydroxylase gene is responsible for cell death of myelodysplasia/leukemia cells.

Tsujioka T, Yokoi A, Itano Y, Takahashi K, Ouchida M, Okamoto S, Kondo T, Suemori S, Tohyama Y, Tohyama K.

Sci Rep. 2015 Nov 18;5:16709. doi: 10.1038/srep16709.

8.

Salbutamol inhibits ubiquitin-mediated survival motor neuron protein degradation in spinal muscular atrophy cells.

Harahap NIF, Nurputra DK, Ar Rochmah M, Shima A, Morisada N, Takarada T, Takeuchi A, Tohyama Y, Yanagisawa S, Nishio H.

Biochem Biophys Rep. 2015 Oct 28;4:351-356. doi: 10.1016/j.bbrep.2015.10.012. eCollection 2015 Dec.

9.

Suppressive effect of membrane-permeable peptides derived from autophosphorylation sites of the IGF-1 receptor on breast cancer cells.

Kuroda Y, Kato-Kogoe N, Tasaki E, Yuasa-Sunagawa M, Yamanegi K, Nakasho K, Nakase I, Futaki S, Tohyama Y, Hirose M.

Eur J Pharmacol. 2015 Oct 15;765:24-33. doi: 10.1016/j.ejphar.2015.08.004. Epub 2015 Aug 12. Erratum in: Eur J Pharmacol. 2015 Nov 15;767:220. Nakase, Ikuhiko [corrected to Nakasho, Ikuhiko].

PMID:
26276395
10.

Rab27a is essential for the formation of neutrophil extracellular traps (NETs) in neutrophil-like differentiated HL60 cells.

Kawakami T, He J, Morita H, Yokoyama K, Kaji H, Tanaka C, Suemori S, Tohyama K, Tohyama Y.

PLoS One. 2014 Jan 3;9(1):e84704. doi: 10.1371/journal.pone.0084704. eCollection 2014.

11.

Intragenic mutations in SMN1 may contribute more significantly to clinical severity than SMN2 copy numbers in some spinal muscular atrophy (SMA) patients.

Yamamoto T, Sato H, Lai PS, Nurputra DK, Harahap NI, Morikawa S, Nishimura N, Kurashige T, Ohshita T, Nakajima H, Yamada H, Nishida Y, Toda S, Takanashi J, Takeuchi A, Tohyama Y, Kubo Y, Saito K, Takeshima Y, Matsuo M, Nishio H.

Brain Dev. 2014 Nov;36(10):914-20. doi: 10.1016/j.braindev.2013.11.009. Epub 2013 Dec 17.

PMID:
24359787
12.

Spinal muscular atrophy: from gene discovery to clinical trials.

Nurputra DK, Lai PS, Harahap NI, Morikawa S, Yamamoto T, Nishimura N, Kubo Y, Takeuchi A, Saito T, Takeshima Y, Tohyama Y, Tay SK, Low PS, Saito K, Nishio H.

Ann Hum Genet. 2013 Sep;77(5):435-63. doi: 10.1111/ahg.12031. Epub 2013 Jul 23. Review.

13.

Tubulin polymerization-promoting protein (TPPP/p25α) promotes unconventional secretion of α-synuclein through exophagy by impairing autophagosome-lysosome fusion.

Ejlerskov P, Rasmussen I, Nielsen TT, Bergström AL, Tohyama Y, Jensen PH, Vilhardt F.

J Biol Chem. 2013 Jun 14;288(24):17313-35. doi: 10.1074/jbc.M112.401174. Epub 2013 Apr 29.

14.

Effects of DNA methyltransferase inhibitors (DNMTIs) on MDS-derived cell lines.

Tsujioka T, Yokoi A, Uesugi M, Kishimoto M, Tochigi A, Suemori S, Tohyama Y, Tohyama K.

Exp Hematol. 2013 Feb;41(2):189-97. doi: 10.1016/j.exphem.2012.10.006. Epub 2012 Oct 17.

PMID:
23085465
15.

Oligopeptides derived from autophosphorylation sites of EGF receptor suppress EGF-stimulated responses in human lung carcinoma A549 cells.

Kuroda Y, Kato-Kogoe N, Tasaki E, Murata E, Ueda K, Abe M, Miyamoto K, Nakase I, Futaki S, Tohyama Y, Hirose M.

Eur J Pharmacol. 2013 Jan 5;698(1-3):87-94. doi: 10.1016/j.ejphar.2012.10.007. Epub 2012 Oct 17.

PMID:
23085023
16.

Neurolytic celiac plexus block reduces occurrence and duration of terminal delirium in patients with pancreatic cancer.

Arai YC, Nishihara M, Kobayashi K, Kanazawa T, Hayashi N, Tohyama Y, Nishida K, Arakawa M, Suzuki C, Kinoshita A, Kondo M, Matsubara S, Yokoe N, Hayashi R, Ohta A, Sato J, Ushida T.

J Anesth. 2013 Feb;27(1):88-92. doi: 10.1007/s00540-012-1486-3. Epub 2012 Sep 19.

PMID:
22990527
17.

Approach to new therapeutics: investigation by the use of MDS-derived cell lines.

Tsujioka T, Matsuoka A, Tohyama Y, Tohyama K.

Curr Pharm Des. 2012;18(22):3204-14. Review.

PMID:
22571700
18.

Rab27b regulates c-kit expression by controlling the secretion of stem cell factor.

Tanaka C, Kaji H, He J, Hazama R, Yokoyama K, Kinoshita E, Tsujioka T, Tohyama K, Yamamura H, Nishio H, Tohyama Y.

Biochem Biophys Res Commun. 2012 Mar 9;419(2):368-73. doi: 10.1016/j.bbrc.2012.02.030. Epub 2012 Feb 13.

PMID:
22349512
19.

High Throughput ELISAs to Measure a Unique Glycan on Transferrin in Cerebrospinal Fluid: A Possible Extension toward Alzheimer's Disease Biomarker Development.

Shirotani K, Futakawa S, Nara K, Hoshi K, Saito T, Tohyama Y, Kitazume S, Yuasa T, Miyajima M, Arai H, Kuno A, Narimatsu H, Hashimoto Y.

Int J Alzheimers Dis. 2011;2011:352787. doi: 10.4061/2011/352787. Epub 2011 Aug 17.

20.

A unique N-glycan on human transferrin in CSF: a possible biomarker for iNPH.

Futakawa S, Nara K, Miyajima M, Kuno A, Ito H, Kaji H, Shirotani K, Honda T, Tohyama Y, Hoshi K, Hanzawa Y, Kitazume S, Imamaki R, Furukawa K, Tasaki K, Arai H, Yuasa T, Abe M, Arai H, Narimatsu H, Hashimoto Y.

Neurobiol Aging. 2012 Aug;33(8):1807-15. doi: 10.1016/j.neurobiolaging.2011.02.023. Epub 2011 Apr 3.

PMID:
21459485
21.

Increased detection of clinically significant antibodies and decreased incidence of delayed haemolytic transfusion reaction with the indirect antiglobulin test potentiated by polyethylene glycol compared to albumin: a Japanese study.

Okutsu M, Ohto H, Yasuda H, Kawabata K, Ono S, Saito S, Sugawara A, Kikuchi M, Miura S, Ishii Y, Watanabe K, Tohyama Y, Nollet KE.

Blood Transfus. 2011 Jul;9(3):311-9. doi: 10.2450/2010.0057-10. Epub 2010 Nov 26.

22.

Rab27a negatively regulates phagocytosis by prolongation of the actin-coating stage around phagosomes.

Yokoyama K, Kaji H, He J, Tanaka C, Hazama R, Kamigaki T, Ku Y, Tohyama K, Tohyama Y.

J Biol Chem. 2011 Feb 18;286(7):5375-82. doi: 10.1074/jbc.M110.171702. Epub 2010 Dec 18.

23.

Multicenter randomized comparison of LigaSure versus conventional surgery for gastrointestinal carcinoma.

Takiguchi N, Nagata M, Soda H, Nomura Y, Takayama W, Yasutomi J, Tohyama Y, Ryu M.

Surg Today. 2010 Nov;40(11):1050-4. doi: 10.1007/s00595-009-4234-z. Epub 2010 Nov 3.

PMID:
21046504
24.

Protein kinase C {delta}-specific activity reporter reveals agonist-evoked nuclear activity controlled by Src family of kinases.

Kajimoto T, Sawamura S, Tohyama Y, Mori Y, Newton AC.

J Biol Chem. 2010 Dec 31;285(53):41896-910. doi: 10.1074/jbc.M110.184028. Epub 2010 Oct 19.

25.

Low-dose gabapentin as useful adjuvant to opioids for neuropathic cancer pain when combined with low-dose imipramine.

Arai YC, Matsubara T, Shimo K, Suetomi K, Nishihara M, Ushida T, Kobayashi K, Suzuki C, Kinoshita A, Kondo M, Matsubara S, Hayashi R, Tohyama Y, Nishida K, Arakawa M.

J Anesth. 2010 Jun;24(3):407-10. doi: 10.1007/s00540-010-0913-6. Epub 2010 Mar 10.

PMID:
20217150
26.

Lenalidomide induces cell death in an MDS-derived cell line with deletion of chromosome 5q by inhibition of cytokinesis.

Matsuoka A, Tochigi A, Kishimoto M, Nakahara T, Kondo T, Tsujioka T, Tasaka T, Tohyama Y, Tohyama K.

Leukemia. 2010 Apr;24(4):748-55. doi: 10.1038/leu.2009.296. Epub 2010 Feb 4.

PMID:
20130600
27.

Close association of p38 and JNK with plasminogen-dependent upregulation of PAI-1 in rat astrocytes in vitro.

Nakajima K, Yamamoto S, Tohyama Y, Kohsaka S.

Neurosci Lett. 2010 Mar 3;471(2):66-9. doi: 10.1016/j.neulet.2010.01.007. Epub 2010 Jan 13.

PMID:
20074614
29.

ATP-induced osteoclast function: the formation of sealing-zone like structure and the secretion of lytic granules via microtubule-deacetylation under the control of Syk.

Hazama R, Qu X, Yokoyama K, Tanaka C, Kinoshita E, He J, Takahashi S, Tohyama K, Yamamura H, Tohyama Y.

Genes Cells. 2009 Jul;14(7):871-84. doi: 10.1111/j.1365-2443.2009.01317.x. Epub 2009 Jun 22.

30.

Small correlation between salivary alpha-amylase activity and pain intensity in patients with cancer pain.

Arai YC, Matsubara T, Shimo K, Osuga T, Ushida T, Suzuki C, Ohta A, Tohyama Y, Nishida K, Arakawa M.

Acta Anaesthesiol Scand. 2009 Mar;53(3):408. doi: 10.1111/j.1399-6576.2008.01833.x. No abstract available.

PMID:
19243335
31.

Protein tyrosine kinase, syk: a key player in phagocytic cells.

Tohyama Y, Yamamura H.

J Biochem. 2009 Mar;145(3):267-73. doi: 10.1093/jb/mvp001. Epub 2009 Jan 4. Review.

PMID:
19124456
32.

Acute effects of combining citalopram and pindolol on regional brain serotonin synthesis in sham operated and olfactory bulbectomized rats.

Nguyen KQ, Tohyama Y, Watanabe A, Hasegawa S, Skelin I, Diksic M.

Neurochem Int. 2009 Mar-Apr;54(3-4):161-71. doi: 10.1016/j.neuint.2008.08.012. Epub 2008 Nov 27.

33.

The VIO soft-coagulation system can prevent pancreatic fistula following pancreatectomy.

Nagakawa Y, Tsuchida A, Saito H, Tohyama Y, Matsudo T, Kawakita H, Ikeda T, Kasuya K, Ozawa T, Aoki T.

J Hepatobiliary Pancreat Surg. 2008;15(4):359-65. doi: 10.1007/s00534-008-1329-7. Epub 2008 Aug 1.

PMID:
18670835
34.

Validation of the revised 2008 WHO diagnostic criteria in 75 suspected cases of myeloproliferative neoplasm.

Kondo T, Okuno N, Naruse H, Kishimoto M, Tasaka T, Tsujioka T, Matsuoka A, Sugihara T, Tohyama Y, Tohyama K.

Leuk Lymphoma. 2008 Sep;49(9):1784-91. doi: 10.1080/10428190802258972.

PMID:
18661406
35.
36.

Induction of apoptosis by epigallocatechin-3-gallate in human lymphoblastoid B cells.

Noda C, He J, Takano T, Tanaka C, Kondo T, Tohyama K, Yamamura H, Tohyama Y.

Biochem Biophys Res Commun. 2007 Nov 3;362(4):951-7. Epub 2007 Aug 24.

PMID:
17803956
37.
38.

Neuronal regulation by which microglia enhance the production of neurotrophic factors for GABAergic, catecholaminergic, and cholinergic neurons.

Nakajima K, Tohyama Y, Maeda S, Kohsaka S, Kurihara T.

Neurochem Int. 2007 May;50(6):807-20. Epub 2007 Mar 2.

PMID:
17459525
39.

Effect of sample collection site on semen parameters of healthy young volunteers.

Oshio S, Yotsukura M, Tohyama Y, Iwabuchi M, Adachi Y, Ashizawa Y, Matsuda H, Iiyama T, Shimizu H, Tomomasa H, Yoshida S, Takeda K, Umeda T.

Arch Androl. 2007 Mar-Apr;53(2):53-8.

PMID:
17453680
40.

[Molecular mechanisms of complement-mediated phagocytosis--the novel function of tyrosine kinase, Syk].

Tohyama Y.

Seikagaku. 2006 Sep;78(9):878-82. Review. Japanese. No abstract available.

PMID:
17052025
41.

Complement-mediated phagocytosis--the role of Syk.

Tohyama Y, Yamamura H.

IUBMB Life. 2006 May-Jun;58(5-6):304-8. Review.

42.

In vitro proliferation of axotomized rat facial nucleus-derived activated microglia in an autocrine fashion.

Nakajima K, Graeber MB, Sonoda M, Tohyama Y, Kohsaka S, Kurihara T.

J Neurosci Res. 2006 Aug 1;84(2):348-59.

PMID:
16673407
43.

Effects of anpirtoline on regional serotonin synthesis in the rat brain: an autoradiographic study.

Watanabe A, Nakai A, Tohyama Y, Nguyen KQ, Diksic M.

Nucl Med Biol. 2006 Apr;33(3):325-32. Epub 2006 Mar 9.

PMID:
16631081
44.

Differential suppression of endotoxin-inducible inflammatory cytokines by nuclear factor kappa B (NFkappaB) inhibitor in rat microglia.

Nakajima K, Matsushita Y, Tohyama Y, Kohsaka S, Kurihara T.

Neurosci Lett. 2006 Jul 3;401(3):199-202. Epub 2006 Mar 31.

PMID:
16580131
45.

Effects of peripheral cannabinoid receptor ligands on motility and polarization in neutrophil-like HL60 cells and human neutrophils.

Kurihara R, Tohyama Y, Matsusaka S, Naruse H, Kinoshita E, Tsujioka T, Katsumata Y, Yamamura H.

J Biol Chem. 2006 May 5;281(18):12908-18. Epub 2006 Mar 2.

47.

Protein-tyrosine kinase Syk is required for pathogen engulfment in complement-mediated phagocytosis.

Shi Y, Tohyama Y, Kadono T, He J, Miah SM, Hazama R, Tanaka C, Tohyama K, Yamamura H.

Blood. 2006 Jun 1;107(11):4554-62. Epub 2006 Jan 31.

PMID:
16449524
48.

Role of nitric oxide on airway microvascular permeability in patients with asthma.

Tohyama Y, Kanazawa H, Fujiwara H, Hirata K, Fujimoto S, Yoshikawa J.

Osaka City Med J. 2005 Jun;51(1):1-9.

PMID:
16334611
49.
50.

Protein-tyrosine kinase, Syk, is required for CXCL12-induced polarization of B cells.

Matsusaka S, Tohyama Y, He J, Shi Y, Hazama R, Kadono T, Kurihara R, Tohyama K, Yamamura H.

Biochem Biophys Res Commun. 2005 Mar 25;328(4):1163-9.

PMID:
15707999

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