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Autoimmune responses and inflammation in type 2 diabetes.

Prasad M, Chen EW, Toh SA, Gascoigne NRJ.

J Leukoc Biol. 2020 Mar 23. doi: 10.1002/JLB.3MR0220-243R. [Epub ahead of print] Review.


A prospective longitudinal study of mobile touch screen device use and musculoskeletal symptoms and visual health in adolescents.

Toh SH, Coenen P, Howie EK, Smith AJ, Mukherjee S, Mackey DA, Straker LM.

Appl Ergon. 2020 May;85:103028. doi: 10.1016/j.apergo.2019.103028. Epub 2020 Jan 17.


Comparing the 5-Year Diabetes Outcomes of Sleeve Gastrectomy and Gastric Bypass: The National Patient-Centered Clinical Research Network (PCORNet) Bariatric Study.

McTigue KM, Wellman R, Nauman E, Anau J, Coley RY, Odor A, Tice J, Coleman KJ, Courcoulas A, Pardee RE, Toh S, Janning CD, Williams N, Cook A, Sturtevant JL, Horgan C, Arterburn D; PCORnet Bariatric Study Collaborative.

JAMA Surg. 2020 Mar 4:e200087. doi: 10.1001/jamasurg.2020.0087. [Epub ahead of print]


Prevalence and Sonographic Detection of Gallbladder Polyps in a Western European Population.

Pickering O, Pucher PH, Toale C, Hand F, Anand E, Cassidy S, McEntee G, Toh SKC.

J Surg Res. 2020 Feb 24;250:226-231. doi: 10.1016/j.jss.2020.01.003. [Epub ahead of print]


Translating claims-based CHA2 DS2 -VaSc and HAS-BLED to ICD-10-CM: Impacts of mapping strategies.

Webster-Clark M, Huang TY, Hou L, Toh S.

Pharmacoepidemiol Drug Saf. 2020 Feb 17. doi: 10.1002/pds.4973. [Epub ahead of print]


Heredity of type 2 diabetes confers increased susceptibility to oxidative stress and inflammation.

Baig S, Shabeer M, Parvaresh Rizi E, Agarwal M, Lee MH, Ooi DSQ, Chia C, Aung N, Ng G, Teo Y, Chhay V, Magkos F, Vidal-Puig A, Seet RCS, Toh SA.

BMJ Open Diabetes Res Care. 2020 Jan;8(1). pii: e000945. doi: 10.1136/bmjdrc-2019-000945.


Use of real-world evidence in regulatory decisions for rare diseases in the United States-Current status and future directions.

Wu J, Wang C, Toh S, Pisa FE, Bauer L.

Pharmacoepidemiol Drug Saf. 2020 Jan 30. doi: 10.1002/pds.4962. [Epub ahead of print] Review.


Effect of probiotics on multi-resistant organism colonisation in persons with spinal cord injury: secondary outcome of ProSCIUTTU, a randomised placebo-controlled trial.

Toh SL, Lee BB, Simpson JM, Rice SA, Kotsiou G, Marial O, Ryan S.

Spinal Cord. 2020 Jan 17. doi: 10.1038/s41393-020-0420-z. [Epub ahead of print]


Interventions and Operations 5 Years After Bariatric Surgery in a Cohort From the US National Patient-Centered Clinical Research Network Bariatric Study.

Courcoulas A, Coley RY, Clark JM, McBride CL, Cirelli E, McTigue K, Arterburn D, Coleman KJ, Wellman R, Anau J, Toh S, Janning CD, Cook AJ, Williams N, Sturtevant JL, Horgan C, Tavakkoli A; PCORnet Bariatric Study Collaborative.

JAMA Surg. 2020 Jan 15. doi: 10.1001/jamasurg.2019.5470. [Epub ahead of print]


Evaluation of the US Food and Drug Administration Sentinel Analysis Tools Using a Comparator with a Different Indication: Comparing the Rates of Gastrointestinal Bleeding in Warfarin and Statin Users.

Carnahan RM, Gagne JJ, Hampp C, Leonard CE, Toh S, Fuller CC, Hennessy S, Hou L, Cocoros NM, Panucci G, Woodworth T, Cosgrove A, Iyer A, Chrischilles EA.

Pharmaceut Med. 2019 Feb;33(1):29-43. doi: 10.1007/s40290-018-00265-w.


Characterising and predicting persistent high-cost utilisers in healthcare: a retrospective cohort study in Singapore.

Ng SHX, Rahman N, Ang IYH, Sridharan S, Ramachandran S, Wang DD, Khoo A, Tan CS, Feng M, Toh SES, Tan XQ.

BMJ Open. 2020 Jan 6;10(1):e031622. doi: 10.1136/bmjopen-2019-031622.


Right-Site Care Programme with a community-based family medicine clinic in Singapore: secondary data analysis of its impact on mortality and healthcare utilisation.

Ang IYH, Ng SH, Rahman N, Nurjono M, Tham TY, Toh SA, Wee HL.

BMJ Open. 2019 Dec 31;9(12):e030718. doi: 10.1136/bmjopen-2019-030718.


Analytic and Data Sharing Options in Real-World Multidatabase Studies of Comparative Effectiveness and Safety of Medical Products.

Toh S.

Clin Pharmacol Ther. 2020 Apr;107(4):834-842. doi: 10.1002/cpt.1754. Epub 2020 Jan 24. Review.


Larynx-preserving reconstruction after extended base of the tongue resection.

Kadota H, Fukushima J, Yoshida S, Kamizono K, Masuda M, Toh S, Yasumatsu R, Nakashima T, Nakagawa T.

J Plast Reconstr Aesthet Surg. 2020 Apr;73(4):740-748. doi: 10.1016/j.bjps.2019.11.018. Epub 2019 Nov 28.


Relationship between immune-related adverse events and the long-term outcomes in recurrent/metastatic head and neck squamous cell carcinoma treated with nivolumab.

Matsuo M, Yasumatsu R, Masuda M, Toh S, Wakasaki T, Hashimoto K, Taura M, Uchi R, Nakagawa T.

Oral Oncol. 2020 Feb;101:104525. doi: 10.1016/j.oraloncology.2019.104525. Epub 2019 Dec 25.


Understanding utilization patterns of biologics and biosimilars in the United States to support postmarketing studies of safety and effectiveness.

Dutcher SK, Fazio-Eynullayeva E, Eworuke E, Carruth A, Dee EC, Blum MD, Nguyen MD, Toh S, Panozzo CA, Lyons JG.

Pharmacoepidemiol Drug Saf. 2019 Dec 11. doi: 10.1002/pds.4908. [Epub ahead of print]


Privacy-protecting estimation of adjusted risk ratios using modified Poisson regression in multi-center studies.

Shu D, Young JG, Toh S.

BMC Med Res Methodol. 2019 Dec 5;19(1):228. doi: 10.1186/s12874-019-0878-6.


Use of Antidiabetic drugs during pregnancy among U.S. women with Livebirth deliveries in the Mini-Sentinel system.

Mott K, Reichman ME, Toh S, Kieswetter C, Haffenreffer K, Andrade SE.

BMC Pregnancy Childbirth. 2019 Nov 27;19(1):441. doi: 10.1186/s12884-019-2609-8.


Clinical features and treatment outcomes of Hodgkin lymphoma: A retrospective review in a Malaysian tertiary hospital.

Boo YL, Ting HSY, Yap DFS, Toh SG, Lim SM.

Blood Res. 2019 Sep;54(3):210-217. doi: 10.5045/br.2019.54.3.210. Epub 2019 Sep 25.


Sylvatic dengue virus type 4 in Aedes aegypti and Aedes albopictus mosquitoes in an urban setting in Peninsular Malaysia.

Johari NA, Voon K, Toh SY, Sulaiman LH, Yap IKS, Lim PKC.

PLoS Negl Trop Dis. 2019 Nov 15;13(11):e0007889. doi: 10.1371/journal.pntd.0007889. eCollection 2019 Nov.


ASLAN003, a potent dihydroorotate dehydrogenase inhibitor for differentiation of acute myeloid leukemia.

Zhou J, Quah JY, Ng Y, Chooi JY, Toh SH, Lin B, Tan TZ, Hosoi H, Osato M, Seet Q, Ooi AGL, Lindmark B, McHale M, Chng WJ.

Haematologica. 2019 Nov 7. pii: haematol.2019.230482. doi: 10.3324/haematol.2019.230482. [Epub ahead of print]


Reproducing Protocol-Based Studies Using Parameterizable Tools-Comparison of Analytic Approaches Used by Two Medical Product Surveillance Networks.

Huang TY, Welch EC, Shinde MU, Platt RW, Filion KB, Azoulay L, Maro JC, Platt R, Toh S.

Clin Pharmacol Ther. 2020 Apr;107(4):966-977. doi: 10.1002/cpt.1698. Epub 2019 Dec 12.


Privacy-protecting multivariable-adjusted distributed regression analysis for multi-center pediatric study.

Toh S, Rifas-Shiman SL, Lin PD, Bailey LC, Forrest CB, Horgan CE, Lunsford D, Moyneur E, Sturtevant JL, Young JG, Block JP; PCORnet Antibiotics and Childhood Growth Study Group.

Pediatr Res. 2019 Oct 2. doi: 10.1038/s41390-019-0596-0. [Epub ahead of print]


Use of Time-Dependent Propensity Scores to Adjust Hazard Ratio Estimates in Cohort Studies with Differential Depletion of Susceptibles.

Wyss R, Gagne JJ, Zhao Y, Zhou EH, Major JM, Wang SV, Desai RJ, Franklin JM, Schneeweiss S, Toh S, Johnson M, Fireman B.

Epidemiology. 2020 Jan;31(1):82-89. doi: 10.1097/EDE.0000000000001107.


Safe Expectations: Current State and Future Directions for Medication Safety in Pregnancy Research.

Wood ME, Andrade SE, Toh S.

Clin Ther. 2019 Dec;41(12):2467-2476. doi: 10.1016/j.clinthera.2019.08.016. Epub 2019 Sep 25.


Ambient and supplemental magnetic fields promote myogenesis via a TRPC1-mitochondrial axis: evidence of a magnetic mitohormetic mechanism.

Yap JLY, Tai YK, Fröhlich J, Fong CHH, Yin JN, Foo ZL, Ramanan S, Beyer C, Toh SJ, Casarosa M, Bharathy N, Kala MP, Egli M, Taneja R, Lee CN, Franco-Obregón A.

FASEB J. 2019 Nov;33(11):12853-12872. doi: 10.1096/fj.201900057R. Epub 2019 Sep 13.


A dual-action chitosan-based nanogel system of triclosan and flurbiprofen for localised treatment of periodontitis.

Aminu N, Chan SY, Yam MF, Toh SM.

Int J Pharm. 2019 Oct 30;570:118659. doi: 10.1016/j.ijpharm.2019.118659. Epub 2019 Sep 4.


Stress-triggered YAP1/SOX2 activation transcriptionally reprograms head and neck squamous cell carcinoma for the acquisition of stemness.

Omori H, Sato K, Nakano T, Wakasaki T, Toh S, Taguchi K, Nakagawa T, Masuda M.

J Cancer Res Clin Oncol. 2019 Oct;145(10):2433-2444. doi: 10.1007/s00432-019-02995-z. Epub 2019 Sep 4.


Identification of potential drug name confusion errors in the Sentinel System.

Cocoros NM, Haynes K, Her Q, Cosgrove A, Dee E, Lin ND, Tu CM, Ding Y, Nguyen M, Toh S.

Pharmacoepidemiol Drug Saf. 2019 Oct;28(10):1405-1410. doi: 10.1002/pds.4891. Epub 2019 Sep 4.


Inverse probability weighted Cox model in multi-site studies without sharing individual-level data.

Shu D, Yoshida K, Fireman BH, Toh S.

Stat Methods Med Res. 2019 Aug 26:962280219869742. doi: 10.1177/0962280219869742. [Epub ahead of print]


Comprehensive analysis of transcriptome profiles in hepatocellular carcinoma.

Jin Y, Lee WY, Toh ST, Tennakoon C, Toh HC, Chow PK, Chung AY, Chong SS, Ooi LL, Sung WK, Lee CG.

J Transl Med. 2019 Aug 20;17(1):273. doi: 10.1186/s12967-019-2025-x.


IL6R-STAT3-ADAR1 (P150) interplay promotes oncogenicity in 1q21(amp) multiple myeloma.

Teoh PJ, Chung TH, Chng PYZ, Toh SHM, Chng WJ.

Haematologica. 2019 Aug 14. pii: haematol.2019.221176. doi: 10.3324/haematol.2019.221176. [Epub ahead of print]


Use of Intrauterine Devices and Risk of HIV Acquisition among Insured Women in the U.S.

Marcus JL, Snowden JM, Murray Horwitz ME, Toh S, Horgan C, Tilney RC, Rajbhandari R, Back S, Westreich DJ.

Clin Infect Dis. 2019 Aug 15. pii: ciz791. doi: 10.1093/cid/ciz791. [Epub ahead of print]


Two-Hour Postprandial Lipoprotein Particle Concentration Differs Between Lean and Obese Individuals.

Parvaresh Rizi E, Baig S, Loh TP, Toh SA, Khoo CM, Tai ES.

Front Physiol. 2019 Jul 16;10:856. doi: 10.3389/fphys.2019.00856. eCollection 2019.


Controlling Confounding in a Study of Oral Anticoagulants: Comparing Disease Risk Scores Developed Using Different Follow-Up Approaches.

Bohn J, Schneeweiss S, Glynn RJ, Toh S, Wyss R, Desai R, Gagne JJ.

EGEMS (Wash DC). 2019 Jul 15;7(1):27. doi: 10.5334/egems.254.


Regulation of stomatal opening and histone modification by photoperiod in Arabidopsis thaliana.

Aoki S, Toh S, Nakamichi N, Hayashi Y, Wang Y, Suzuki T, Tsuji H, Kinoshita T.

Sci Rep. 2019 Jul 22;9(1):10054. doi: 10.1038/s41598-019-46440-0.


Characterization of high healthcare utilizer groups using administrative data from an electronic medical record database.

Ng SH, Rahman N, Ang IYH, Sridharan S, Ramachandran S, Wang DD, Tan CS, Toh SA, Tan XQ.

BMC Health Serv Res. 2019 Jul 5;19(1):452. doi: 10.1186/s12913-019-4239-2.


Antipsychotic Use and Stroke: A Retrospective Comparative Study in a Non-Elderly Population.

Taylor LG, Panucci G, Mosholder AD, Toh S, Huang TY.

J Clin Psychiatry. 2019 Jun 4;80(4). pii: 18m12636. doi: 10.4088/JCP.18m12636.


Retrospective evaluation of healthcare utilisation and mortality of two post-discharge care programmes in Singapore.

Ang IYH, Tan CS, Nurjono M, Tan XQ, Koh GC, Vrijhoef HJM, Tan S, Ng SE, Toh SA.

BMJ Open. 2019 May 22;9(5):e027220. doi: 10.1136/bmjopen-2018-027220.


Oxidative stress mediates depot-specific functional differences of human adipose-derived stem cells.

Sriram S, Yuan C, Chakraborty S, Tay W, Park M, Shabbir A, Toh SA, Han W, Sugii S.

Stem Cell Res Ther. 2019 May 21;10(1):141. doi: 10.1186/s13287-019-1240-y.


Genes Involved in Oxidative Stress Pathways Are Differentially Expressed in Circulating Mononuclear Cells Derived From Obese Insulin-Resistant and Lean Insulin-Sensitive Individuals Following a Single Mixed-Meal Challenge.

Baig S, Parvaresh Rizi E, Chia C, Shabeer M, Aung N, Loh TP, Magkos F, Vidal-Puig A, Seet RCS, Khoo CM, Toh SA.

Front Endocrinol (Lausanne). 2019 Apr 24;10:256. doi: 10.3389/fendo.2019.00256. eCollection 2019.


Plasma Protein and MicroRNA Biomarkers of Insulin Resistance: A Network-Based Integrative -Omics Analysis.

Choi H, Koh HWL, Zhou L, Cheng H, Loh TP, Parvaresh Rizi E, Toh SA, Ronnett GV, Huang BE, Khoo CM.

Front Physiol. 2019 Apr 5;10:379. doi: 10.3389/fphys.2019.00379. eCollection 2019.


Evaluating the use of bootstrapping in cohort studies conducted with 1:1 propensity score matching-A plasmode simulation study.

Desai RJ, Wyss R, Abdia Y, Toh S, Johnson M, Lee H, Karami S, Major JM, Nguyen M, Wang SV, Franklin JM, Gagne JJ.

Pharmacoepidemiol Drug Saf. 2019 Jun;28(6):879-886. doi: 10.1002/pds.4784. Epub 2019 Apr 24.


Sound-Alike Look-Alike Confusion and Matching Medication Product Attributes: Simulated Case-Control Studies.

Her QL, Toh S.

Ann Pharmacother. 2019 Oct;53(10):973-980. doi: 10.1177/1060028019838239. Epub 2019 Apr 18.


Comparing Prescribing and Dispensing Data of the PCORnet Common Data Model Within PCORnet Antibiotics and Childhood Growth Study.

Lin PD, Daley MF, Boone-Heinonen J, Rifas-Shiman SL, Bailey LC, Forrest CB, Horgan CE, Sturtevant JL, Toh S, Young JG, Block JP; PCORnet Antibiotics and Childhood Growth Study Group.

EGEMS (Wash DC). 2019 Apr 12;7(1):11. doi: 10.5334/egems.274.


Rechallenge of ponatinib in chronic myeloid leukaemia after hepatotoxicity.

Boo YL, Liam CCK, Toh SG, Lim SM.

Hong Kong Med J. 2019 Apr;25(2):162-163. doi: 10.12809/hkmj187420. No abstract available.


Implementation fidelity of a strategy to integrate service delivery: learnings from a transitional care program for individuals with complex needs in Singapore.

Nurjono M, Shrestha P, Ang IYH, Shiraz F, Yoong JS, Toh SES, Vrijhoef HJM.

BMC Health Serv Res. 2019 Mar 19;19(1):177. doi: 10.1186/s12913-019-3980-x.


Loneliness amongst Low-Socioeconomic Status Elderly Singaporeans and its Association with Perceptions of the Neighbourhood Environment.

Wee LE, Tsang TYY, Yi H, Toh SA, Lee GL, Yee J, Lee S, Oen K, Koh GCH.

Int J Environ Res Public Health. 2019 Mar 18;16(6). pii: E967. doi: 10.3390/ijerph16060967.


Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches.

Chakarov S, Lim HY, Tan L, Lim SY, See P, Lum J, Zhang XM, Foo S, Nakamizo S, Duan K, Kong WT, Gentek R, Balachander A, Carbajo D, Bleriot C, Malleret B, Tam JKC, Baig S, Shabeer M, Toh SES, Schlitzer A, Larbi A, Marichal T, Malissen B, Chen J, Poidinger M, Kabashima K, Bajenoff M, Ng LG, Angeli V, Ginhoux F.

Science. 2019 Mar 15;363(6432). pii: eaau0964. doi: 10.1126/science.aau0964.


Ex vivo model for a new bilateral antimesenteric V-modified side-to-side isoperistaltic anastomosis to prevent recurrence in ileocolic Crohn's disease.

Celentano V, Luvisetto F, Toh S.

Ann R Coll Surg Engl. 2019 May;101(5):313-317. doi: 10.1308/rcsann.2019.0026. Epub 2019 Mar 11.


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