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Cost-Effectiveness Analysis of Oral Anticoagulants in Stroke Prevention among Patients with Atrial Fibrillation in Taiwan.

Liao CT, Lee MC, Chen ZC, Ku LE, Wang JD, Toh HS.

Acta Cardiol Sin. 2020 Jan;36(1):50-61. doi: 10.6515/ACS.202001_36(1).20190511A.


Group A Streptococcus NAD-Glycohydrolase Inhibits Caveolin 1-Mediated Internalization Into Human Epithelial Cells.

Toh H, Lin CY, Nakajima S, Aikawa C, Nozawa T, Nakagawa I.

Front Cell Infect Microbiol. 2019 Nov 28;9:398. doi: 10.3389/fcimb.2019.00398. eCollection 2019.


Reduced economic burden of AIDS-defining illnesses associated with adherence to antiretroviral therapy.

Toh HS, Yang CT, Yang KL, Ku HC, Liao CT, Kuo S, Tang HJ, Ko WC, Ou HT, Ko NY.

Int J Infect Dis. 2019 Nov 15;91:44-49. doi: 10.1016/j.ijid.2019.11.010. [Epub ahead of print]


Metabolic pathway analyses identify proline biosynthesis pathway as a promoter of liver tumorigenesis.

Ding Z, Ericksen RE, Escande-Beillard N, Lee QY, Loh A, Denil S, Steckel M, Haegebarth A, Wai Ho TS, Chow P, Toh HC, Reversade B, Gruenewald S, Han W.

J Hepatol. 2019 Nov 11. pii: S0168-8278(19)30667-1. doi: 10.1016/j.jhep.2019.10.026. [Epub ahead of print]


Non-transmissible MV Vector with Segmented RNA Genome Establishes Different Types of iPSCs from Hematopoietic Cells.

Hiramoto T, Tahara M, Liao J, Soda Y, Miura Y, Kurita R, Hamana H, Inoue K, Kohara H, Miyamoto S, Hijikata Y, Okano S, Yamaguchi Y, Oda Y, Ichiyanagi K, Toh H, Sasaki H, Kishi H, Ryo A, Muraguchi A, Takeda M, Tani K.

Mol Ther. 2020 Jan 8;28(1):129-141. doi: 10.1016/j.ymthe.2019.09.007. Epub 2019 Sep 12.


Chloroquine modulates inflammatory autoimmune responses through Nurr1 in autoimmune diseases.

Park TY, Jang Y, Kim W, Shin J, Toh HT, Kim CH, Yoon HS, Leblanc P, Kim KS.

Sci Rep. 2019 Oct 29;9(1):15559. doi: 10.1038/s41598-019-52085-w.


Taiwan guideline on oral pre-exposure prophylaxis for HIV prevention - 2018 update.

Yen-Hao Chu I, Wen-Wei Ku S, Li CW, Toh HS, Yang CJ, Wu KS, Wu HJ, Chen SS, Kuo JH, Lin HH, Ko NY.

J Microbiol Immunol Infect. 2019 Sep 28. pii: S1684-1182(19)30143-4. doi: 10.1016/j.jmii.2019.09.003. [Epub ahead of print] Review.


Expression of CD38 on Macrophages Predicts Improved Prognosis in Hepatocellular Carcinoma.

Lam JH, Ng HHM, Lim CJ, Sim XN, Malavasi F, Li H, Loh JJH, Sabai K, Kim JK, Ong CCH, Loh T, Leow WQ, Choo SP, Toh HC, Lee SY, Chan CY, Chew V, Lim TS, Yeong J, Lim TKH.

Front Immunol. 2019 Sep 4;10:2093. doi: 10.3389/fimmu.2019.02093. eCollection 2019.


Localized basal left ventricular dyssynchrony induced by manifest accessory pathway: Successful differentiation from cardiac involvement of sarcoidosis with administration of flecainide acetate.

Tsuda D, Mori S, Yokota S, Izawa Y, Shimoyama S, Suzuki M, Takahashi Y, Toh H, Toba T, Tanaka H, Fujiwara S, Hirata KI.

J Electrocardiol. 2019 Nov - Dec;57:87-89. doi: 10.1016/j.jelectrocard.2019.09.015. Epub 2019 Sep 6.


Broad Heterochromatic Domains Open in Gonocyte Development Prior to De Novo DNA Methylation.

Yamanaka S, Nishihara H, Toh H, Eijy Nagai LA, Hashimoto K, Park SJ, Shibuya A, Suzuki AM, Tanaka Y, Nakai K, Carninci P, Sasaki H, Siomi H.

Dev Cell. 2019 Oct 7;51(1):21-34.e5. doi: 10.1016/j.devcel.2019.07.023. Epub 2019 Aug 29.


The rotational position of the aortic root related to its underlying ventricular support.

Amofa D, Mori S, Toh H, Ta HT, Du Plessis M, Davis N, Izawa Y, Spicer DE, Anderson RH, Tretter JT.

Clin Anat. 2019 Nov;32(8):1107-1117. doi: 10.1002/ca.23462. Epub 2019 Sep 10.


Comprehensive analysis of transcriptome profiles in hepatocellular carcinoma.

Jin Y, Lee WY, Toh ST, Tennakoon C, Toh HC, Chow PK, Chung AY, Chong SS, Ooi LL, Sung WK, Lee CG.

J Transl Med. 2019 Aug 20;17(1):273. doi: 10.1186/s12967-019-2025-x.


Injury patterns associated with personal mobility devices and electric bicycles: an analysis from an acute general hospital in Singapore.

Cha Sow King C, Liu M, Patel S, Goo TT, Lim WW, Toh HC.

Singapore Med J. 2019 Jul 30. doi: 10.11622/smedj.2019084. [Epub ahead of print]


Aging of spermatogonial stem cells by Jnk-mediated glycolysis activation.

Kanatsu-Shinohara M, Yamamoto T, Toh H, Kazuki Y, Kazuki K, Imoto J, Ikeo K, Oshima M, Shirahige K, Iwama A, Nabeshima Y, Sasaki H, Shinohara T.

Proc Natl Acad Sci U S A. 2019 Aug 13;116(33):16404-16409. doi: 10.1073/pnas.1904980116. Epub 2019 Jul 29.


Group A Streptococcus modulates RAB1- and PIK3C3 complex-dependent autophagy.

Toh H, Nozawa T, Minowa-Nozawa A, Hikichi M, Nakajima S, Aikawa C, Nakagawa I.

Autophagy. 2019 Jun 14:1-13. doi: 10.1080/15548627.2019.1628539. [Epub ahead of print]


Draft Genome Sequence of Butyricimonas faecihominis 30A1, Isolated from Feces of a Japanese Alzheimer's Disease Patient.

Nguyen TTT, Oshima K, Toh H, Khasnobish A, Fujii Y, Arakawa K, Morita H.

Microbiol Resour Announc. 2019 Jun 6;8(23). pii: e00462-19. doi: 10.1128/MRA.00462-19.


Vascular changes in diabetic retinopathy-a longitudinal study in the Nile rat.

Toh H, Smolentsev A, Bozadjian RV, Keeley PW, Lockwood MD, Sadjadi R, Clegg DO, Blodi BA, Coffey PJ, Reese BE, Thomson JA.

Lab Invest. 2019 Oct;99(10):1547-1560. doi: 10.1038/s41374-019-0264-3. Epub 2019 May 17.


Antimicrobial Activity of Lactobacillus Species Against Carbapenem-Resistant Enterobacteriaceae.

Chen CC, Lai CC, Huang HL, Huang WY, Toh HS, Weng TC, Chuang YC, Lu YC, Tang HJ.

Front Microbiol. 2019 Apr 18;10:789. doi: 10.3389/fmicb.2019.00789. eCollection 2019.


Identification of Mouse and Human Antibody Repertoires by Next-Generation Sequencing.

Sun L, Kono N, Toh H, Xue H, Sano K, Suzuki T, Ainai A, Orba Y, Yamagishi J, Hasegawa H, Takahashi Y, Itamura S, Ohnishi K.

J Vis Exp. 2019 Mar 15;(145). doi: 10.3791/58804.


World Cancer Day 2019 - Don't Stop Thinking About Tomorrow.

Farid M, Toh HC.

Ann Acad Med Singapore. 2019 Feb;48(2):42-44. No abstract available.


Correction: Early assessment of tumor response to photodynamic therapy using combined diffuse optical and diffuse correlation spectroscopy to predict treatment outcome.

Thong PSP, Lee K, Toh HJ, Dong J, Tee CS, Low KP, Chang PH, Bhuvaneswari R, Tan NC, Soo KC.

Oncotarget. 2019 Feb 22;10(16):1602. doi: 10.18632/oncotarget.26742. eCollection 2019 Feb 22.


Comments on "Sensitivity and Specificity Analysis: Use of Emoticon for Screening of Depression in Elderly in Singapore".

Toh HJ, Tan L, Sim LK, Low JA.

J Am Psychiatr Nurses Assoc. 2019 Sep/Oct;25(5):346-347. doi: 10.1177/1078390319834624. Epub 2019 Mar 13. No abstract available.


Intra-operative difficult airway identification and critical airway communication: how effective are we?: A retrospective review of 6318 cases.

Zhang J, Toh H, Ong S, Chua MSL, Chen Q, Lam S, Swe M.

Eur J Anaesthesiol. 2019 Mar;36(3):239-241. doi: 10.1097/EJA.0000000000000919. No abstract available.


Loss of BCAA Catabolism during Carcinogenesis Enhances mTORC1 Activity and Promotes Tumor Development and Progression.

Ericksen RE, Lim SL, McDonnell E, Shuen WH, Vadiveloo M, White PJ, Ding Z, Kwok R, Lee P, Radda GK, Toh HC, Hirschey MD, Han W.

Cell Metab. 2019 May 7;29(5):1151-1165.e6. doi: 10.1016/j.cmet.2018.12.020. Epub 2019 Jan 17.


Erratum: The empowerment of all modalities against cancer.

Han S, Toh HC.

Singapore Med J. 2018 Dec;59(12):661. doi: 10.11622/smedj.2018148. No abstract available.


Cardiac FDG/PET imaging mimicking sarcoidosis.

Lai JKC, Teo E, Lichtenstein M, Toh HB, Sivaratnam D.

J Nucl Cardiol. 2019 Jun;26(3):1025-1027. doi: 10.1007/s12350-018-01579-7. Epub 2019 Jan 9. No abstract available.


Simultaneous three Enterobacteriaceae with different bla NDM-1-encoding plasmids in a patient transferred from mainland China to Taiwan.

Lai CC, Chen CC, Lu YC, Chen HJ, Su BA, Weng TC, Chiu YH, Toh HS, Zhang CC, Chiang SR, Chuang YC, Tang HJ.

Infect Drug Resist. 2018 Dec 7;11:2555-2560. doi: 10.2147/IDR.S179024. eCollection 2018.


The empowerment of all modalities against cancer.

Han S, Toh HC.

Singapore Med J. 2018 Nov;59(11):560-561. doi: 10.11622/smedj.2018133. No abstract available. Erratum in: Singapore Med J. 2018 Dec;59(12):661.


NLRX1 Negatively Regulates Group A Streptococcus Invasion and Autophagy Induction by Interacting With the Beclin 1-UVRAG Complex.

Aikawa C, Nakajima S, Karimine M, Nozawa T, Minowa-Nozawa A, Toh H, Yamada S, Nakagawa I.

Front Cell Infect Microbiol. 2018 Nov 14;8:403. doi: 10.3389/fcimb.2018.00403. eCollection 2018.


Patient-Surrogate Agreement in Advance Care Planning: Who Are the Surrogates and Are They Making the Right Decisions?

Toh HJ, Tan L, Sim LK, Low JA.

Ann Acad Med Singapore. 2018 Oct;47(10):431-434. No abstract available.


LAMTOR2/LAMTOR1 complex is required for TAX1BP1-mediated xenophagy.

Lin CY, Nozawa T, Minowa-Nozawa A, Toh H, Aikawa C, Nakagawa I.

Cell Microbiol. 2019 Apr;21(4):e12981. doi: 10.1111/cmi.12981. Epub 2019 Jan 21.


Cancer Immunotherapy - The Target is Precisely on The Cancer and Also Not.

Koo SL, Wang WW, Toh HC.

Ann Acad Med Singapore. 2018 Sep;47(9):381-387. Review.


The impact of earlier intervention by an antimicrobial stewardship team for specific antimicrobials in a single weekly intervention.

Hagiwara D, Sato K, Miyazaki M, Kamada M, Moriwaki N, Nakano T, Shiotsuka S, Tokushige C, Toh H, Kamimura H, Togawa A, Takata T.

Int J Infect Dis. 2018 Dec;77:34-39. doi: 10.1016/j.ijid.2018.09.025. Epub 2018 Oct 4.


RAB30 regulates PI4KB (phosphatidylinositol 4-kinase beta)-dependent autophagy against group A Streptococcus.

Nakajima K, Nozawa T, Minowa-Nozawa A, Toh H, Yamada S, Aikawa C, Nakagawa I.

Autophagy. 2019 Mar;15(3):466-477. doi: 10.1080/15548627.2018.1532260. Epub 2018 Oct 18.


90-Day Hospital Readmissions of Patients in a Geriatric Acute Care Ward in Singapore.

Tan RRQ, Toh HJ, Yap PLK, Jiao N, Wang W.

Clin Nurs Res. 2018 Sep 18:1054773818801483. doi: 10.1177/1054773818801483. [Epub ahead of print]


Serial observation of electrocardiographic responses to corticosteroid therapy in a patient with right ventricular-predominant cardiac sarcoidosis.

Toh H, Mori S, Keno M, Yokota S, Shinkura Y, Izawa Y, Nagamatsu Y, Shimoyama S, Fukuzawa K, Doi T, Hirata KI.

J Electrocardiol. 2018 Jul - Aug;51(4):658-662. doi: 10.1016/j.jelectrocard.2018.04.008. Epub 2018 Apr 11.


Multidimensional analyses reveal distinct immune microenvironment in hepatitis B virus-related hepatocellular carcinoma.

Lim CJ, Lee YH, Pan L, Lai L, Chua C, Wasser M, Lim TKH, Yeong J, Toh HC, Lee SY, Chan CY, Goh BK, Chung A, Heikenwälder M, Ng IO, Chow P, Albani S, Chew V.

Gut. 2019 May;68(5):916-927. doi: 10.1136/gutjnl-2018-316510. Epub 2018 Jul 3.


Diagnosis and impact of neuropathic pain in leprosy patients in Nepal after completion of multidrug therapy.

Toh HS, Maharjan J, Thapa R, Neupane KD, Shah M, Baral S, Hagge DA, Napit IB, Lockwood DNJ.

PLoS Negl Trop Dis. 2018 Jul 2;12(7):e0006610. doi: 10.1371/journal.pntd.0006610. eCollection 2018 Jul.


Methods to Investigate the Roles of Progranulin in Angiogenesis Using In Vitro Strategies and Transgenic Mouse Models.

Toh H, Daniels E, Bateman A.

Methods Mol Biol. 2018;1806:329-360. doi: 10.1007/978-1-4939-8559-3_22.


Cancer immunotherapy-the end of the beginning.

Toh HC.

Chin Clin Oncol. 2018 Apr;7(2):12. doi: 10.21037/cco.2018.04.03. No abstract available.


Development of a new patient-derived xenograft humanised mouse model to study human-specific tumour microenvironment and immunotherapy.

Zhao Y, Shuen TWH, Toh TB, Chan XY, Liu M, Tan SY, Fan Y, Yang H, Lyer SG, Bonney GK, Loh E, Chang KTE, Tan TC, Zhai W, Chan JKY, Chow EK, Chee CE, Lee GH, Dan YY, Chow PK, Toh HC, Lim SG, Chen Q.

Gut. 2018 Oct;67(10):1845-1854. doi: 10.1136/gutjnl-2017-315201. Epub 2018 Mar 30.


Sensitivity and Specificity Analysis: Use of Emoticon for Screening of Depression in Elderly in Singapore.

Tan L, Toh HJ, Sim LK, Low JA.

J Am Psychiatr Nurses Assoc. 2018 Sep/Oct;24(5):452-456. doi: 10.1177/1078390318766665. Epub 2018 Mar 30.


Chemogenomic Profiling of Human and Microbial FK506-Binding Proteins.

Pomplun S, Sippel C, Hähle A, Tay D, Shima K, Klages A, Ünal CM, Rieß B, Toh HT, Hansen G, Yoon HS, Bracher A, Preiser P, Rupp J, Steinert M, Hausch F.

J Med Chem. 2018 Apr 26;61(8):3660-3673. doi: 10.1021/acs.jmedchem.8b00137. Epub 2018 Apr 5.


Optimal reconstruction of left ventricular outflow tract obstruction before surgical myectomy in a case with hypertrophic obstructive cardiomyopathy.

Toh H, Mori S, Shimoyama S, Izawa Y, Yokota S, Shinkura Y, Takeshige R, Nagasawa A, Soga F, Tanaka H, Shinke T, Yokawa K, Matsueda T, Okita Y, Hirata KI.

Echocardiography. 2018 Apr;35(4):537-540. doi: 10.1111/echo.13864. Epub 2018 Mar 22.


Man with back pain and fever.

Ho AFW, Pek PP, Toh HC.

CJEM. 2018 Mar;20(2):313-314. doi: 10.1017/cem.2017.336. No abstract available.


Analysis of Reasons for Potentially Preventable Hospital Transfers Using the Modified INTERACT-II Tool.

Magpantay GC, Toh HJ, Low JA, Chia WK.

J Am Med Dir Assoc. 2018 Feb;19(2):181-182. doi: 10.1016/j.jamda.2017.11.010. Epub 2017 Dec 26. No abstract available.


Derivation of Human Trophoblast Stem Cells.

Okae H, Toh H, Sato T, Hiura H, Takahashi S, Shirane K, Kabayama Y, Suyama M, Sasaki H, Arima T.

Cell Stem Cell. 2018 Jan 4;22(1):50-63.e6. doi: 10.1016/j.stem.2017.11.004. Epub 2017 Dec 14.


A light-assisted in situ embedment of silver nanoparticles to prepare functionalized fabrics.

Toh HS, Faure RL, Mohd Amin LB, Hay CYF, George S.

Nanotechnol Sci Appl. 2017 Nov 30;10:147-162. doi: 10.2147/NSA.S139484. eCollection 2017.


Distorted antibody repertoire developed in the absence of pre-B cell receptor formation.

Sun L, Kono N, Shimizu T, Toh H, Xue H, Numata O, Ato M, Itamura S, Ohnishi K.

Biochem Biophys Res Commun. 2018 Jan 1;495(1):1411-1417. doi: 10.1016/j.bbrc.2017.11.171. Epub 2017 Nov 27.


Role of UHRF1 in de novo DNA methylation in oocytes and maintenance methylation in preimplantation embryos.

Maenohara S, Unoki M, Toh H, Ohishi H, Sharif J, Koseki H, Sasaki H.

PLoS Genet. 2017 Oct 4;13(10):e1007042. doi: 10.1371/journal.pgen.1007042. eCollection 2017 Oct.

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