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Items: 11

1.

Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy.

Toepfer CN, Garfinkel AC, Venturini G, Wakimoto H, Repetti G, Alamo L, Sharma A, Agarwal R, Ewoldt JF, Cloonan P, Letendre J, Lun M, Olivotto I, Colan S, Ashley E, Jacoby D, Michels M, Redwood CS, Watkins HC, Day SM, Staples JF, Padrón R, Chopra A, Ho CY, Chen CS, Pereira AC, Seidman JG, Seidman CE.

Circulation. 2020 Jan 27. doi: 10.1161/CIRCULATIONAHA.119.042339. [Epub ahead of print]

PMID:
31983222
2.

Novel Therapies for Prevention and Early Treatment of Cardiomyopathies.

Repetti GG, Toepfer CN, Seidman JG, Seidman CE.

Circ Res. 2019 May 24;124(11):1536-1550. doi: 10.1161/CIRCRESAHA.119.313569.

PMID:
31120825
3.

Genetic Variants Associated With Cancer Therapy-Induced Cardiomyopathy.

Garcia-Pavia P, Kim Y, Restrepo-Cordoba MA, Lunde IG, Wakimoto H, Smith AM, Toepfer CN, Getz K, Gorham J, Patel P, Ito K, Willcox JA, Arany Z, Li J, Owens AT, Govind R, Nuñez B, Mazaika E, Bayes-Genis A, Walsh R, Finkelman B, Lupon J, Whiffin N, Serrano I, Midwinter W, Wilk A, Bardaji A, Ingold N, Buchan R, Tayal U, Pascual-Figal DA, de Marvao A, Ahmad M, Garcia-Pinilla JM, Pantazis A, Dominguez F, John Baksi A, O'Regan DP, Rosen SD, Prasad SK, Lara-Pezzi E, Provencio M, Lyon AR, Alonso-Pulpon L, Cook SA, DePalma SR, Barton PJR, Aplenc R, Seidman JG, Ky B, Ware JS, Seidman CE.

Circulation. 2019 Jul 2;140(1):31-41. doi: 10.1161/CIRCULATIONAHA.118.037934. Epub 2019 Apr 16.

4.

SarcTrack.

Toepfer CN, Sharma A, Cicconet M, Garfinkel AC, Mücke M, Neyazi M, Willcox JAL, Agarwal R, Schmid M, Rao J, Ewoldt J, Pourquié O, Chopra A, Chen CS, Seidman JG, Seidman CE.

Circ Res. 2019 Apr 12;124(8):1172-1183. doi: 10.1161/CIRCRESAHA.118.314505.

5.

Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin.

Toepfer CN, Wakimoto H, Garfinkel AC, McDonough B, Liao D, Jiang J, Tai AC, Gorham JM, Lunde IG, Lun M, Lynch TL 4th, McNamara JW, Sadayappan S, Redwood CS, Watkins HC, Seidman JG, Seidman CE.

Sci Transl Med. 2019 Jan 23;11(476). pii: eaat1199. doi: 10.1126/scitranslmed.aat1199.

PMID:
30674652
6.

Hierarchical and stage-specific regulation of murine cardiomyocyte maturation by serum response factor.

Guo Y, Jardin BD, Zhou P, Sethi I, Akerberg BN, Toepfer CN, Ai Y, Li Y, Ma Q, Guatimosim S, Hu Y, Varuzhanyan G, VanDusen NJ, Zhang D, Chan DC, Yuan GC, Seidman CE, Seidman JG, Pu WT.

Nat Commun. 2018 Sep 21;9(1):3837. doi: 10.1038/s41467-018-06347-2.

7.

Differentiation and Contractile Analysis of GFP-Sarcomere Reporter hiPSC-Cardiomyocytes.

Sharma A, Toepfer CN, Schmid M, Garfinkel AC, Seidman CE.

Curr Protoc Hum Genet. 2018 Jan 24;96:21.12.1-21.12.12. doi: 10.1002/cphg.53.

8.

CRISPR/Cas9-Mediated Fluorescent Tagging of Endogenous Proteins in Human Pluripotent Stem Cells.

Sharma A, Toepfer CN, Ward T, Wasson L, Agarwal R, Conner DA, Hu JH, Seidman CE.

Curr Protoc Hum Genet. 2018 Jan 24;96:21.11.1-21.11.20. doi: 10.1002/cphg.52.

9.

Revisiting Frank-Starling: regulatory light chain phosphorylation alters the rate of force redevelopment (ktr ) in a length-dependent fashion.

Toepfer CN, West TG, Ferenczi MA.

J Physiol. 2016 Sep 15;594(18):5237-54. doi: 10.1113/JP272441. Epub 2016 Jul 24.

10.

A post-MI power struggle: adaptations in cardiac power occur at the sarcomere level alongside MyBP-C and RLC phosphorylation.

Toepfer CN, Sikkel MB, Caorsi V, Vydyanath A, Torre I, Copeland O, Lyon AR, Marston SB, Luther PK, Macleod KT, West TG, Ferenczi MA.

Am J Physiol Heart Circ Physiol. 2016 Aug 1;311(2):H465-75. doi: 10.1152/ajpheart.00899.2015. Epub 2016 May 27.

11.

Power output of skinned skeletal muscle fibres from the cheetah (Acinonyx jubatus).

West TG, Toepfer CN, Woledge RC, Curtin NA, Rowlerson A, Kalakoutis M, Hudson P, Wilson AM.

J Exp Biol. 2013 Aug 1;216(Pt 15):2974-82. doi: 10.1242/jeb.083667. Epub 2013 Apr 11.

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