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Items: 1 to 50 of 122

1.

Neuronal nitric oxide synthase regulation of calcium cycling in ventricular cardiomyocytes is independent of Cav1.2 channel modulation under basal conditions.

Ebner J, Cagalinec M, Kubista H, Todt H, Szabo PL, Kiss A, Podesser BK, Cserne Szappanos H, Hool LC, Hilber K, Koenig X.

Pflugers Arch. 2020 Jan;472(1):61-74. doi: 10.1007/s00424-019-02335-7. Epub 2019 Dec 10.

PMID:
31822999
2.

Pharmacological Profile of the Bradycardic Agent Ivabradine on Human Cardiac Ion Channels.

Haechl N, Ebner J, Hilber K, Todt H, Koenig X.

Cell Physiol Biochem. 2019;53(1):36-48. doi: 10.33594/000000119.

3.

Calcium current properties in dystrophin-deficient ventricular cardiomyocytes from aged mdx mice.

Rubi L, Todt H, Kubista H, Koenig X, Hilber K.

Physiol Rep. 2018 Jan;6(1). doi: 10.14814/phy2.13567.

4.

Distinct modulation of inactivation by a residue in the pore domain of voltage-gated Na+ channels: mechanistic insights from recent crystal structures.

Cervenka R, Lukacs P, Gawali VS, Ke S, Koenig X, Rubi L, Zarrabi T, Hilber K, Sandtner W, Stary-Weinzinger A, Todt H.

Sci Rep. 2018 Jan 12;8(1):631. doi: 10.1038/s41598-017-18919-1.

5.

C2-Modified Sparteine Derivatives Are a New Class of Potentially Long-Acting Sodium Channel Blockers.

Gawali VS, Simeonov S, Drescher M, Knott T, Scheel O, Kudolo J, Kählig H, Hochenegg U, Roller A, Todt H, Maulide N.

ChemMedChem. 2017 Nov 22;12(22):1819-1822. doi: 10.1002/cmdc.201700568. Epub 2017 Nov 6.

PMID:
29045055
6.

Modulation of the heart's electrical properties by the anticonvulsant drug retigabine.

Rubi L, Kovar M, Zebedin-Brandl E, Koenig X, Dominguez-Rodriguez M, Todt H, Kubista H, Boehm S, Hilber K.

Toxicol Appl Pharmacol. 2017 Aug 15;329:309-317. doi: 10.1016/j.taap.2017.06.018. Epub 2017 Jun 20.

7.

Mechanism of Inactivation in Voltage-Gated Na(+) Channels.

Gawali VS, Todt H.

Curr Top Membr. 2016;78:409-50. doi: 10.1016/bs.ctm.2016.07.004. Epub 2016 Aug 1.

PMID:
27586291
8.

Decreased inward rectifier potassium current IK1 in dystrophin-deficient ventricular cardiomyocytes.

Rubi L, Koenig X, Kubista H, Todt H, Hilber K.

Channels (Austin). 2017 Mar 4;11(2):101-108. doi: 10.1080/19336950.2016.1228498. Epub 2016 Aug 25.

9.

Mechanism of Modification, by Lidocaine, of Fast and Slow Recovery from Inactivation of Voltage-Gated Na⁺ Channels.

Gawali VS, Lukacs P, Cervenka R, Koenig X, Rubi L, Hilber K, Sandtner W, Todt H.

Mol Pharmacol. 2015 Nov;88(5):866-79. doi: 10.1124/mol.115.099580. Epub 2015 Sep 10.

PMID:
26358763
10.

Proper Voltage-Dependent Ion Channel Function in Dysferlin-Deficient Cardiomyocytes.

Rubi L, Gawali VS, Kubista H, Todt H, Hilber K, Koenig X.

Cell Physiol Biochem. 2015;36(3):1049-58. doi: 10.1159/000430278. Epub 2015 Jun 18.

11.

Influence of halophytic hosts on their parasites-the case of Plicosepalus acaciae.

Veste M, Todt H, Breckle SW.

AoB Plants. 2014 Dec 16;7. pii: plu084. doi: 10.1093/aobpla/plu084.

12.

Late cardiac sodium current can be assessed using automated patch-clamp.

Chevalier M, Amuzescu B, Gawali V, Todt H, Knott T, Scheel O, Abriel H.

F1000Res. 2014 Oct 16;3:245. doi: 10.12688/f1000research.5544.1. eCollection 2014.

13.

A novel noninvasive procedure for high-throughput screening of major seed traits.

Rolletschek H, Fuchs J, Friedel S, Börner A, Todt H, Jakob PM, Borisjuk L.

Plant Biotechnol J. 2015 Feb;13(2):188-99. doi: 10.1111/pbi.12245. Epub 2014 Sep 9.

14.

Exploring the structure of the voltage-gated Na+ channel by an engineered drug access pathway to the receptor site for local anesthetics.

Lukacs P, Gawali VS, Cervenka R, Ke S, Koenig X, Rubi L, Zarrabi T, Hilber K, Stary-Weinzinger A, Todt H.

J Biol Chem. 2014 Aug 1;289(31):21770-81. doi: 10.1074/jbc.M113.541763. Epub 2014 Jun 19.

15.

The gammaherpesviruses Kaposi's sarcoma-associated herpesvirus and murine gammaherpesvirus 68 modulate the Toll-like receptor-induced proinflammatory cytokine response.

Bussey KA, Reimer E, Todt H, Denker B, Gallo A, Konrad A, Ottinger M, Adler H, Stürzl M, Brune W, Brinkmann MM.

J Virol. 2014 Aug;88(16):9245-59. doi: 10.1128/JVI.00841-14. Epub 2014 Jun 4.

16.

Discovery of X-ray pulsations from a massive star.

Oskinova LM, Nazé Y, Todt H, Huenemoerder DP, Ignace R, Hubrig S, Hamann WR.

Nat Commun. 2014 Jun 3;5:4024. doi: 10.1038/ncomms5024.

PMID:
24892504
17.

Enhanced currents through L-type calcium channels in cardiomyocytes disturb the electrophysiology of the dystrophic heart.

Koenig X, Rubi L, Obermair GJ, Cervenka R, Dang XB, Lukacs P, Kummer S, Bittner RE, Kubista H, Todt H, Hilber K.

Am J Physiol Heart Circ Physiol. 2014 Feb 15;306(4):H564-H573. doi: 10.1152/ajpheart.00441.2013. Epub 2013 Dec 13.

18.

Anti-addiction drug ibogaine inhibits voltage-gated ionic currents: a study to assess the drug's cardiac ion channel profile.

Koenig X, Kovar M, Rubi L, Mike AK, Lukacs P, Gawali VS, Todt H, Hilber K, Sandtner W.

Toxicol Appl Pharmacol. 2013 Dec 1;273(2):259-68. doi: 10.1016/j.taap.2013.05.012. Epub 2013 May 22.

19.

Voltage-gated ion channel dysfunction precedes cardiomyopathy development in the dystrophic heart.

Koenig X, Dysek S, Kimbacher S, Mike AK, Cervenka R, Lukacs P, Nagl K, Dang XB, Todt H, Bittner RE, Hilber K.

PLoS One. 2011;6(5):e20300. doi: 10.1371/journal.pone.0020300. Epub 2011 May 23.

20.

A molecular switch between the outer and the inner vestibules of the voltage-gated Na+ channel.

Zarrabi T, Cervenka R, Sandtner W, Lukacs P, Koenig X, Hilber K, Mille M, Lipkind GM, Fozzard HA, Todt H.

J Biol Chem. 2010 Dec 10;285(50):39458-70. doi: 10.1074/jbc.M110.132886. Epub 2010 Oct 6.

21.

The outer vestibule of the Na+ channel-toxin receptor and modulator of permeation as well as gating.

Cervenka R, Zarrabi T, Lukacs P, Todt H.

Mar Drugs. 2010 Apr 21;8(4):1373-93. doi: 10.3390/md8041373. Review.

22.

Sodium current properties of primary skeletal myocytes and cardiomyocytes derived from different mouse strains.

Mille M, Koenig X, Zebedin E, Uhrin P, Cervenka R, Todt H, Hilber K.

Pflugers Arch. 2009 Mar;457(5):1023-33. doi: 10.1007/s00424-008-0570-x. Epub 2008 Aug 13.

23.

Development of hippocampal sclerosis after a complex febrile seizure.

Merkenschlager A, Todt H, Pfluger T, Bernhard MK.

Eur J Pediatr. 2009 Apr;168(4):487-90. doi: 10.1007/s00431-008-0776-0. Epub 2008 Jul 17.

PMID:
18633642
24.

Effects of duramycin on cardiac voltage-gated ion channels.

Zebedin E, Koenig X, Radenkovic M, Pankevych H, Todt H, Freissmuth M, Hilber K.

Naunyn Schmiedebergs Arch Pharmacol. 2008 Mar;377(1):87-100. doi: 10.1007/s00210-007-0248-5. Epub 2008 Jan 5.

PMID:
18176799
25.

Speeding the recovery from ultraslow inactivation of voltage-gated Na+ channels by metal ion binding to the selectivity filter: a foot-on-the-door?

Szendroedi J, Sandtner W, Zarrabi T, Zebedin E, Hilber K, Dudley SC Jr, Fozzard HA, Todt H.

Biophys J. 2007 Dec 15;93(12):4209-24. Epub 2007 Aug 24.

26.

C2C12 skeletal muscle cells adopt cardiac-like sodium current properties in a cardiac cell environment.

Zebedin E, Mille M, Speiser M, Zarrabi T, Sandtner W, Latzenhofer B, Todt H, Hilber K.

Am J Physiol Heart Circ Physiol. 2007 Jan;292(1):H439-50. Epub 2006 Sep 15.

27.

[Acute effects on the health of children after accidental exposure to epichlorohydrine].

Basting I, Hoopmann M, Ehrenstein V, Suchenwirth R, Tödt H, Reichert J, Dressel H, Rosenberger A, Schmid M, Nowak D, Radon K.

Gesundheitswesen. 2006 May;68(5):309-15. German.

PMID:
16773552
28.

Geographical distribution of acute symptoms after a train collision involving epichlorohydrin exposure.

Radon K, Rosenberger A, Ehrenstein V, Hoopmann M, Basting I, Tödt H, Reichert J, Dressel H, Schmid M, Suchenwirth R, Nowak D.

Environ Res. 2006 Sep;102(1):46-51. Epub 2006 Mar 15.

PMID:
16540103
29.

Selectivity filter residues contribute unequally to pore stabilization in voltage-gated sodium channels.

Hilber K, Sandtner W, Zarrabi T, Zebedin E, Kudlacek O, Fozzard HA, Todt H.

Biochemistry. 2005 Oct 25;44(42):13874-82.

PMID:
16229476
30.

Lidocaine: a foot in the door of the inner vestibule prevents ultra-slow inactivation of a voltage-gated sodium channel.

Sandtner W, Szendroedi J, Zarrabi T, Zebedin E, Hilber K, Glaaser I, Fozzard HA, Dudley SC, Todt H.

Mol Pharmacol. 2004 Sep;66(3):648-57.

PMID:
15322257
31.

Fiber type conversion alters inactivation of voltage-dependent sodium currents in murine C2C12 skeletal muscle cells.

Zebedin E, Sandtner W, Galler S, Szendroedi J, Just H, Todt H, Hilber K.

Am J Physiol Cell Physiol. 2004 Aug;287(2):C270-80. Epub 2004 Mar 24.

32.

The Kleine-Levin syndrome - effects of treatment with lithium -.

Poppe M, Friebel D, Reuner U, Todt H, Koch R, Heubner G.

Neuropediatrics. 2003 Jun;34(3):113-9. Review.

PMID:
12910433
33.

Dual rate-dependent cardiac electrophysiologic effects of haloperidol: slowing of intraventricular conduction and lengthening of repolarization.

Mörtl D, Agneter E, Krivanek P, Koppatz K, Todt H.

J Cardiovasc Pharmacol. 2003 Jun;41(6):870-9.

PMID:
12775964
34.

Interaction between fast and ultra-slow inactivation in the voltage-gated sodium channel. Does the inactivation gate stabilize the channel structure?

Hilber K, Sandtner W, Kudlacek O, Schreiner B, Glaaser I, Schütz W, Fozzard HA, Dudley SC, Todt H.

J Biol Chem. 2002 Oct 4;277(40):37105-15. Epub 2002 Jul 23.

35.

The selectivity filter of the voltage-gated sodium channel is involved in channel activation.

Hilber K, Sandtner W, Kudlacek O, Glaaser IW, Weisz E, Kyle JW, French RJ, Fozzard HA, Dudley SC, Todt H.

J Biol Chem. 2001 Jul 27;276(30):27831-9. Epub 2001 May 29.

36.

Fulminant course in a case of diffuse myelinoclastic encephalitis-- a case report.

Poppe M, Brück W, Hahn G, Weissbrich B, Heubner G, Goebel HH, Todt H.

Neuropediatrics. 2001 Feb;32(1):41-4.

PMID:
11315201
37.

Temporary response of localized intracranial mast cell sarcoma to combination chemotherapy.

Guenther PP, Huebner A, Sobottka SB, Neumeister V, Weissbach G, Todt H, Parwaresch R.

J Pediatr Hematol Oncol. 2001 Feb;23(2):134-8.

PMID:
11216707
38.

Ultra-slow inactivation in mu1 Na+ channels is produced by a structural rearrangement of the outer vestibule.

Todt H, Dudley SC Jr, Kyle JW, French RJ, Fozzard HA.

Biophys J. 1999 Mar;76(3):1335-45.

39.
40.

Differential effect of dofetilide on ventricular repolarization during steady state and during restitution in vivo.

Todt H, Zojer N, Schütz W.

J Cardiovasc Pharmacol. 1994 Dec;24(6):1010-3.

PMID:
7898064
41.

Frequency-dependent effects of amitriptyline and maprotiline on conduction in the guinea pig His-Purkinje-system in vivo.

Todt H, Zojer N, Djamshidian-Tehrani S, Koppatz K, Krivanek P, Raberger G, Schütz W.

Naunyn Schmiedebergs Arch Pharmacol. 1994 Dec;350(6):670-6.

PMID:
7708124
42.

Prolongation of the QT interval by dofetilide modulates rate-dependent effects of mexiletine on intraventricular conduction.

Todt H, Zojer N, Raberger G, Schütz W.

Eur J Pharmacol. 1994 Nov 14;265(1-2):43-52.

PMID:
7883028
43.

[Joubert syndrome combined with unilateral facial paralysis: a rare variant of Joubert syndrome].

Stute M, Tödt HC, Schlüter B, Pahl H, Oelschläger U.

Klin Padiatr. 1994 Sep-Oct;206(5):397-401. German.

PMID:
7799618
44.

[Nursing care--here's where research starts].

Tødt H.

Sygeplejersken. 1994 Jul 6;94(27):24-5, 32. Danish. No abstract available.

PMID:
7801291
45.
46.

Effect of ajmaline on sustained ventricular tachycardia induced by programmed electrical stimulation in conscious dogs after myocardial infarction.

Todt H, Krumpl G, Zojer N, Krejcy K, Raberger G.

Naunyn Schmiedebergs Arch Pharmacol. 1993 Sep;348(3):290-7.

PMID:
7694159
47.
48.
49.

Epicardial His bundle recordings in the guinea pig in vivo.

Todt H, Raberger G.

J Pharmacol Toxicol Methods. 1992 May;27(3):191-5.

PMID:
1498346
50.

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