Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 431

1.

The DILfrequency study is an adaptive trial to identify optimal IL-2 dosing in patients with type 1 diabetes.

Seelig E, Howlett J, Porter L, Truman L, Heywood J, Kennet J, Arbon EL, Anselmiova K, Walker NM, Atkar R, Pekalski ML, Rytina E, Evans M, Wicker LS, Todd JA, Mander AP, Bond S, Waldron-Lynch F.

JCI Insight. 2018 Oct 4;3(19). pii: 99306. doi: 10.1172/jci.insight.99306. [Epub ahead of print]

2.

Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes.

Westra HJ, Martínez-Bonet M, Onengut-Gumuscu S, Lee A, Luo Y, Teslovich N, Worthington J, Martin J, Huizinga T, Klareskog L, Rantapaa-Dahlqvist S, Chen WM, Quinlan A, Todd JA, Eyre S, Nigrovic PA, Gregersen PK, Rich SS, Raychaudhuri S.

Nat Genet. 2018 Oct;50(10):1366-1374. doi: 10.1038/s41588-018-0216-7. Epub 2018 Sep 17.

PMID:
30224649
3.

The plasma biomarker soluble SIGLEC-1 is associated with the type I interferon transcriptional signature, ethnic background and renal disease in systemic lupus erythematosus.

Oliveira JJ, Karrar S, Rainbow DB, Pinder CL, Clarke P, Rubio García A, Al-Assar O, Burling K, Morris S, Stratton R, Vyse TJ, Wicker LS, Todd JA, Ferreira RC.

Arthritis Res Ther. 2018 Jul 27;20(1):152. doi: 10.1186/s13075-018-1649-1.

4.

Approaches and advances in the genetic causes of autoimmune disease and their implications.

Inshaw JRJ, Cutler AJ, Burren OS, Stefana MI, Todd JA.

Nat Immunol. 2018 Jun 20. doi: 10.1038/s41590-018-0129-8. [Epub ahead of print] Review.

PMID:
29925982
5.

Genomic atlas of the human plasma proteome.

Sun BB, Maranville JC, Peters JE, Stacey D, Staley JR, Blackshaw J, Burgess S, Jiang T, Paige E, Surendran P, Oliver-Williams C, Kamat MA, Prins BP, Wilcox SK, Zimmerman ES, Chi A, Bansal N, Spain SL, Wood AM, Morrell NW, Bradley JR, Janjic N, Roberts DJ, Ouwehand WH, Todd JA, Soranzo N, Suhre K, Paul DS, Fox CS, Plenge RM, Danesh J, Runz H, Butterworth AS.

Nature. 2018 Jun;558(7708):73-79. doi: 10.1038/s41586-018-0175-2. Epub 2018 Jun 6.

PMID:
29875488
6.

Evidence that UBASH3 is a causal gene for type 1 diabetes.

Todd JA.

Eur J Hum Genet. 2018 May 14. doi: 10.1038/s41431-018-0142-2. [Epub ahead of print] No abstract available.

7.

Taxonomy based on science is necessary for global conservation.

Thomson SA, Pyle RL, Ahyong ST, Alonso-Zarazaga M, Ammirati J, Araya JF, Ascher JS, Audisio TL, Azevedo-Santos VM, Bailly N, Baker WJ, Balke M, Barclay MVL, Barrett RL, Benine RC, Bickerstaff JRM, Bouchard P, Bour R, Bourgoin T, Boyko CB, Breure ASH, Brothers DJ, Byng JW, Campbell D, Ceríaco LMP, Cernák I, Cerretti P, Chang CH, Cho S, Copus JM, Costello MJ, Cseh A, Csuzdi C, Culham A, D'Elía G, d'Udekem d'Acoz C, Daneliya ME, Dekker R, Dickinson EC, Dickinson TA, van Dijk PP, Dijkstra KB, Dima B, Dmitriev DA, Duistermaat L, Dumbacher JP, Eiserhardt WL, Ekrem T, Evenhuis NL, Faille A, Fernández-Triana JL, Fiesler E, Fishbein M, Fordham BG, Freitas AVL, Friol NR, Fritz U, Frøslev T, Funk VA, Gaimari SD, Garbino GST, Garraffoni ARS, Geml J, Gill AC, Gray A, Grazziotin FG, Greenslade P, Gutiérrez EE, Harvey MS, Hazevoet CJ, He K, He X, Helfer S, Helgen KM, van Heteren AH, Hita Garcia F, Holstein N, Horváth MK, Hovenkamp PH, Hwang WS, Hyvönen J, Islam MB, Iverson JB, Ivie MA, Jaafar Z, Jackson MD, Jayat JP, Johnson NF, Kaiser H, Klitgård BB, Knapp DG, Kojima JI, Kõljalg U, Kontschán J, Krell FT, Krisai-Greilhuber I, Kullander S, Latella L, Lattke JE, Lencioni V, Lewis GP, Lhano MG, Lujan NK, Luksenburg JA, Mariaux J, Marinho-Filho J, Marshall CJ, Mate JF, McDonough MM, Michel E, Miranda VFO, Mitroiu MD, Molinari J, Monks S, Moore AJ, Moratelli R, Murányi D, Nakano T, Nikolaeva S, Noyes J, Ohl M, Oleas NH, Orrell T, Páll-Gergely B, Pape T, Papp V, Parenti LR, Patterson D, Pavlinov IY, Pine RH, Poczai P, Prado J, Prathapan D, Rabeler RK, Randall JE, Rheindt FE, Rhodin AGJ, Rodríguez SM, Rogers DC, Roque FO, Rowe KC, Ruedas LA, Salazar-Bravo J, Salvador RB, Sangster G, Sarmiento CE, Schigel DS, Schmidt S, Schueler FW, Segers H, Snow N, Souza-Dias PGB, Stals R, Stenroos S, Stone RD, Sturm CF, Štys P, Teta P, Thomas DC, Timm RM, Tindall BJ, Todd JA, Triebel D, Valdecasas AG, Vizzini A, Vorontsova MS, de Vos JM, Wagner P, Watling L, Weakley A, Welter-Schultes F, Whitmore D, Wilding N, Will K, Williams J, Wilson K, Winston JE, Wüster W, Yanega D, Yeates DK, Zaher H, Zhang G, Zhang ZQ, Zhou HZ.

PLoS Biol. 2018 Mar 14;16(3):e2005075. doi: 10.1371/journal.pbio.2005075. eCollection 2018 Mar. No abstract available.

8.

Eocene greenhouse climate revealed by coupled clumped isotope-Mg/Ca thermometry.

Evans D, Sagoo N, Renema W, Cotton LJ, Müller W, Todd JA, Saraswati PK, Stassen P, Ziegler M, Pearson PN, Valdes PJ, Affek HP.

Proc Natl Acad Sci U S A. 2018 Feb 6;115(6):1174-1179. doi: 10.1073/pnas.1714744115. Epub 2018 Jan 22.

9.

Allele-specific methylation of type 1 diabetes susceptibility genes.

Kindt ASD, Fuerst RW, Knoop J, Laimighofer M, Telieps T, Hippich M, Woerheide MA, Wahl S, Wilson R, Sedlmeier EM, Hommel A, Todd JA, Krumsiek J, Ziegler AG, Bonifacio E.

J Autoimmun. 2018 May;89:63-74. doi: 10.1016/j.jaut.2017.11.008. Epub 2017 Dec 8.

10.

The chromosome 6q22.33 region is associated with age at diagnosis of type 1 diabetes and disease risk in those diagnosed under 5 years of age.

Inshaw JRJ, Walker NM, Wallace C, Bottolo L, Todd JA.

Diabetologia. 2018 Jan;61(1):147-157. doi: 10.1007/s00125-017-4440-y. Epub 2017 Oct 5.

11.

Chromosome contacts in activated T cells identify autoimmune disease candidate genes.

Burren OS, Rubio García A, Javierre BM, Rainbow DB, Cairns J, Cooper NJ, Lambourne JJ, Schofield E, Castro Dopico X, Ferreira RC, Coulson R, Burden F, Rowlston SP, Downes K, Wingett SW, Frontini M, Ouwehand WH, Fraser P, Spivakov M, Todd JA, Wicker LS, Cutler AJ, Wallace C.

Genome Biol. 2017 Sep 4;18(1):165. doi: 10.1186/s13059-017-1285-0.

12.

Capturing the systemic immune signature of a norovirus infection: an n-of-1 case study within a clinical trial.

Cutler AJ, Oliveira J, Ferreira RC, Challis B, Walker NM, Caddy S, Lu J, Stevens HE, Smyth DJ, Pekalski ML, Kennet J, Hunter KMD, Goodfellow I, Wicker LS, Todd JA, Waldron-Lynch F.

Wellcome Open Res. 2017 Oct 5;2:28. doi: 10.12688/wellcomeopenres.11300.3. eCollection 2017.

13.

Neonatal and adult recent thymic emigrants produce IL-8 and express complement receptors CR1 and CR2.

Pekalski ML, García AR, Ferreira RC, Rainbow DB, Smyth DJ, Mashar M, Brady J, Savinykh N, Dopico XC, Mahmood S, Duley S, Stevens HE, Walker NM, Cutler AJ, Waldron-Lynch F, Dunger DB, Shannon-Lowe C, Coles AJ, Jones JL, Wallace C, Todd JA, Wicker LS.

JCI Insight. 2017 Aug 17;2(16). pii: 93739. doi: 10.1172/jci.insight.93739. [Epub ahead of print]

14.

Childhood adiposity and risk of type 1 diabetes: A Mendelian randomization study.

Censin JC, Nowak C, Cooper N, Bergsten P, Todd JA, Fall T.

PLoS Med. 2017 Aug 1;14(8):e1002362. doi: 10.1371/journal.pmed.1002362. eCollection 2017 Aug.

15.

Cells with Treg-specific FOXP3 demethylation but low CD25 are prevalent in autoimmunity.

Ferreira RC, Simons HZ, Thompson WS, Rainbow DB, Yang X, Cutler AJ, Oliveira J, Castro Dopico X, Smyth DJ, Savinykh N, Mashar M, Vyse TJ, Dunger DB, Baxendale H, Chandra A, Wallace C, Todd JA, Wicker LS, Pekalski ML.

J Autoimmun. 2017 Nov;84:75-86. doi: 10.1016/j.jaut.2017.07.009. Epub 2017 Jul 23.

16.

Clinical utility of single molecule counting technology for quantification of KIM-1 in patients with heart failure and chronic kidney disease.

Miao J, Friedman E, Wu AHB, Todd JA, Estis J, Xu X, Nolan N, Bishop JJ, Lenihan DJ.

Clin Biochem. 2017 Nov;50(16-17):889-895. doi: 10.1016/j.clinbiochem.2017.06.002. Epub 2017 Jun 12.

PMID:
28614696
17.

Time-calibrated molecular phylogeny of pteropods.

Burridge AK, Hörnlein C, Janssen AW, Hughes M, Bush SL, Marlétaz F, Gasca R, Pierrot-Bults AC, Michel E, Todd JA, Young JR, Osborn KJ, Menken SBJ, Peijnenburg KTCA.

PLoS One. 2017 Jun 12;12(6):e0177325. doi: 10.1371/journal.pone.0177325. eCollection 2017.

18.

In-depth immunophenotyping data of IL-6R on the human peripheral regulatory T cell (Treg) compartment.

Ferreira RC, Rainbow DB, Rubio García A, Pekalski ML, Porter L, Oliveira JJ, Waldron-Lynch F, Wicker LS, Todd JA.

Data Brief. 2017 May 2;12:676-691. doi: 10.1016/j.dib.2017.04.043. eCollection 2017 Jun.

19.

Overexpression of the Cytokine BAFF and Autoimmunity Risk.

Steri M, Orrù V, Idda ML, Pitzalis M, Pala M, Zara I, Sidore C, Faà V, Floris M, Deiana M, Asunis I, Porcu E, Mulas A, Piras MG, Lobina M, Lai S, Marongiu M, Serra V, Marongiu M, Sole G, Busonero F, Maschio A, Cusano R, Cuccuru G, Deidda F, Poddie F, Farina G, Dei M, Virdis F, Olla S, Satta MA, Pani M, Delitala A, Cocco E, Frau J, Coghe G, Lorefice L, Fenu G, Ferrigno P, Ban M, Barizzone N, Leone M, Guerini FR, Piga M, Firinu D, Kockum I, Lima Bomfim I, Olsson T, Alfredsson L, Suarez A, Carreira PE, Castillo-Palma MJ, Marcus JH, Congia M, Angius A, Melis M, Gonzalez A, Alarcón Riquelme ME, da Silva BM, Marchini M, Danieli MG, Del Giacco S, Mathieu A, Pani A, Montgomery SB, Rosati G, Hillert J, Sawcer S, D'Alfonso S, Todd JA, Novembre J, Abecasis GR, Whalen MB, Marrosu MG, Meloni A, Sanna S, Gorospe M, Schlessinger D, Fiorillo E, Zoledziewska M, Cucca F.

N Engl J Med. 2017 Apr 27;376(17):1615-1626. doi: 10.1056/NEJMoa1610528.

20.

Mercaptopurine versus placebo to prevent recurrence of Crohn's disease after surgical resection (TOPPIC): a multicentre, double-blind, randomised controlled trial.

Mowat C, Arnott I, Cahill A, Smith M, Ahmad T, Subramanian S, Travis S, Morris J, Hamlin J, Dhar A, Nwokolo C, Edwards C, Creed T, Bloom S, Yousif M, Thomas L, Campbell S, Lewis SJ, Sebastian S, Sen S, Lal S, Hawkey C, Murray C, Cummings F, Goh J, Lindsay JO, Arebi N, Potts L, McKinley AJ, Thomson JM, Todd JA, Collie M, Dunlop MG, Mowat A, Gaya DR, Winter J, Naismith GD, Ennis H, Keerie C, Lewis S, Prescott RJ, Kennedy NA, Satsangi J; TOPPIC Study Group.

Lancet Gastroenterol Hepatol. 2016 Dec;1(4):273-282. doi: 10.1016/S2468-1253(16)30078-4. Epub 2016 Aug 30.

21.

Human IL-6RhiTIGIT- CD4+CD127lowCD25+ T cells display potent in vitro suppressive capacity and a distinct Th17 profile.

Ferreira RC, Rainbow DB, Rubio García A, Pekalski ML, Porter L, Oliveira JJ, Waldron-Lynch F, Wicker LS, Todd JA.

Clin Immunol. 2017 Jun;179:25-39. doi: 10.1016/j.clim.2017.03.002. Epub 2017 Mar 9.

22.

Beta-Cell Fragility As a Common Underlying Risk Factor in Type 1 and Type 2 Diabetes.

Liston A, Todd JA, Lagou V.

Trends Mol Med. 2017 Feb;23(2):181-194. doi: 10.1016/j.molmed.2016.12.005. Epub 2017 Jan 21. Review.

PMID:
28117227
23.

A method for identifying genetic heterogeneity within phenotypically defined disease subgroups.

Liley J, Todd JA, Wallace C.

Nat Genet. 2017 Feb;49(2):310-316. doi: 10.1038/ng.3751. Epub 2016 Dec 26.

24.

Type 1 Diabetes Prevention: A Goal Dependent on Accepting a Diagnosis of an Asymptomatic Disease.

Ziegler AG, Bonifacio E, Powers AC, Todd JA, Harrison LC, Atkinson MA.

Diabetes. 2016 Nov;65(11):3233-3239.

25.

Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters.

Javierre BM, Burren OS, Wilder SP, Kreuzhuber R, Hill SM, Sewitz S, Cairns J, Wingett SW, Várnai C, Thiecke MJ, Burden F, Farrow S, Cutler AJ, Rehnström K, Downes K, Grassi L, Kostadima M, Freire-Pritchett P, Wang F; BLUEPRINT Consortium, Stunnenberg HG, Todd JA, Zerbino DR, Stegle O, Ouwehand WH, Frontini M, Wallace C, Spivakov M, Fraser P.

Cell. 2016 Nov 17;167(5):1369-1384.e19. doi: 10.1016/j.cell.2016.09.037.

26.

Rebranding asymptomatic type 1 diabetes: the case for autoimmune beta cell disorder as a pathological and diagnostic entity.

Bonifacio E, Mathieu C, Nepom GT, Ziegler AG, Anhalt H, Haller MJ, Harrison LC, Hebrok M, Kushner JA, Norris JM, Peakman M, Powers AC, Todd JA, Atkinson MA.

Diabetologia. 2017 Jan;60(1):35-38. Epub 2016 Oct 26.

27.

Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial.

Todd JA, Evangelou M, Cutler AJ, Pekalski ML, Walker NM, Stevens HE, Porter L, Smyth DJ, Rainbow DB, Ferreira RC, Esposito L, Hunter KM, Loudon K, Irons K, Yang JH, Bell CJ, Schuilenburg H, Heywood J, Challis B, Neupane S, Clarke P, Coleman G, Dawson S, Goymer D, Anselmiova K, Kennet J, Brown J, Caddy SL, Lu J, Greatorex J, Goodfellow I, Wallace C, Tree TI, Evans M, Mander AP, Bond S, Wicker LS, Waldron-Lynch F.

PLoS Med. 2016 Oct 11;13(10):e1002139. doi: 10.1371/journal.pmed.1002139. eCollection 2016 Oct.

28.

Formation of the Isthmus of Panama.

O'Dea A, Lessios HA, Coates AG, Eytan RI, Restrepo-Moreno SA, Cione AL, Collins LS, de Queiroz A, Farris DW, Norris RD, Stallard RF, Woodburne MO, Aguilera O, Aubry MP, Berggren WA, Budd AF, Cozzuol MA, Coppard SE, Duque-Caro H, Finnegan S, Gasparini GM, Grossman EL, Johnson KG, Keigwin LD, Knowlton N, Leigh EG, Leonard-Pingel JS, Marko PB, Pyenson ND, Rachello-Dolmen PG, Soibelzon E, Soibelzon L, Todd JA, Vermeij GJ, Jackson JB.

Sci Adv. 2016 Aug 17;2(8):e1600883. doi: 10.1126/sciadv.1600883. eCollection 2016 Aug. Review.

29.

CHiCP: a web-based tool for the integrative and interactive visualization of promoter capture Hi-C datasets.

Schofield EC, Carver T, Achuthan P, Freire-Pritchett P, Spivakov M, Todd JA, Burren OS.

Bioinformatics. 2016 Aug 15;32(16):2511-3. doi: 10.1093/bioinformatics/btw173. Epub 2016 Apr 8.

30.

β-cell specific T-lymphocyte response has a distinct inflammatory phenotype in children with Type 1 diabetes compared with adults.

Arif S, Gibson VB, Nguyen V, Bingley PJ, Todd JA, Guy C, Dunger DB, Dayan CM, Powrie J, Lorenc A, Peakman M.

Diabet Med. 2017 Mar;34(3):419-425. doi: 10.1111/dme.13153. Epub 2016 May 30.

PMID:
27151105
31.

Intolerable secretion and diabetes in tolerant transgenic mice, revisited.

Todd JA.

Nat Genet. 2016 Apr 27;48(5):476-7. doi: 10.1038/ng.3560.

PMID:
27120442
32.

Primary prevention of beta-cell autoimmunity and type 1 diabetes - The Global Platform for the Prevention of Autoimmune Diabetes (GPPAD) perspectives.

Ziegler AG, Danne T, Dunger DB, Berner R, Puff R, Kiess W, Agiostratidou G, Todd JA, Bonifacio E.

Mol Metab. 2016 Feb 22;5(4):255-262. doi: 10.1016/j.molmet.2016.02.003. eCollection 2016 Apr. Review.

33.

Evaluation of near-surface stress distributions in dissimilar welded joint by scanning acoustic microscopy.

Kwak DR, Yoshida S, Sasaki T, Todd JA, Park IK.

Ultrasonics. 2016 Apr;67:9-17. doi: 10.1016/j.ultras.2015.12.006. Epub 2015 Dec 19.

PMID:
26773788
34.

Protocol of the adaptive study of IL-2 dose frequency on regulatory T cells in type 1 diabetes (DILfrequency): a mechanistic, non-randomised, repeat dose, open-label, response-adaptive study.

Truman LA, Pekalski ML, Kareclas P, Evangelou M, Walker NM, Howlett J, Mander AP, Kennet J, Wicker LS, Bond S, Todd JA, Waldron-Lynch F.

BMJ Open. 2015 Dec 8;5(12):e009799. doi: 10.1136/bmjopen-2015-009799.

35.

Ptpn22 and Cd2 Variations Are Associated with Altered Protein Expression and Susceptibility to Type 1 Diabetes in Nonobese Diabetic Mice.

Fraser HI, Howlett S, Clark J, Rainbow DB, Stanford SM, Wu DJ, Hsieh YW, Maine CJ, Christensen M, Kuchroo V, Sherman LA, Podolin PL, Todd JA, Steward CA, Peterson LB, Bottini N, Wicker LS.

J Immunol. 2015 Nov 15;195(10):4841-52. doi: 10.4049/jimmunol.1402654. Epub 2015 Oct 5.

36.

Epigenetic analysis of regulatory T cells using multiplex bisulfite sequencing.

Rainbow DB, Yang X, Burren O, Pekalski ML, Smyth DJ, Klarqvist MD, Penkett CJ, Brugger K, Martin H, Todd JA, Wallace C, Wicker LS.

Eur J Immunol. 2015 Nov;45(11):3200-3. doi: 10.1002/eji.201545646. Epub 2015 Oct 1. No abstract available.

37.

Erratum. Blood and Islet Phenotypes Indicate Immunological Heterogeneity in Type 1 Diabetes. Diabetes 2014;63:3835-3845.

Arif S, Leete P, Nguyen V, Marks K, Nor NM, Estorninho M, Kronenberg-Versteeg D, Bingley PJ, Todd JA, Guy C, Dunger DB, Powrie J, Willcox A, Foulis AK, Richardson SJ, de Rinaldis E, Morgan NG, Lorenc A, Peakman M.

Diabetes. 2015 Sep;64(9):3334. doi: 10.2337/db15-er09a. No abstract available.

38.

Natural Variation in Interleukin-2 Sensitivity Influences Regulatory T-Cell Frequency and Function in Individuals With Long-standing Type 1 Diabetes.

Yang JH, Cutler AJ, Ferreira RC, Reading JL, Cooper NJ, Wallace C, Clarke P, Smyth DJ, Boyce CS, Gao GJ, Todd JA, Wicker LS, Tree TI.

Diabetes. 2015 Nov;64(11):3891-902. doi: 10.2337/db15-0516. Epub 2015 Jul 29.

39.

Corrigendum: Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls.

Fortune MD, Guo H, Burren O, Schofield E, Walker NM, Ban M, Sawcer SJ, Bowes J, Worthington J, Barton A, Eyre S, Todd JA, Wallace C.

Nat Genet. 2015 Aug;47(8):962. doi: 10.1038/ng0815-962c. No abstract available.

PMID:
26220137
40.

Additive and interaction effects at three amino acid positions in HLA-DQ and HLA-DR molecules drive type 1 diabetes risk.

Hu X, Deutsch AJ, Lenz TL, Onengut-Gumuscu S, Han B, Chen WM, Howson JM, Todd JA, de Bakker PI, Rich SS, Raychaudhuri S.

Nat Genet. 2015 Aug;47(8):898-905. doi: 10.1038/ng.3353. Epub 2015 Jul 13.

41.

Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping.

Wallace C, Cutler AJ, Pontikos N, Pekalski ML, Burren OS, Cooper JD, García AR, Ferreira RC, Guo H, Walker NM, Smyth DJ, Rich SS, Onengut-Gumuscu S, Sawcer SJ, Ban M, Richardson S, Todd JA, Wicker LS.

PLoS Genet. 2015 Jun 24;11(6):e1005272. doi: 10.1371/journal.pgen.1005272. eCollection 2015 Jun.

42.

Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls.

Fortune MD, Guo H, Burren O, Schofield E, Walker NM, Ban M, Sawcer SJ, Bowes J, Worthington J, Barton A, Eyre S, Todd JA, Wallace C.

Nat Genet. 2015 Jul;47(7):839-46. doi: 10.1038/ng.3330. Epub 2015 Jun 8. Erratum in: Nat Genet. 2015 Aug;47(8):962.

43.

Widespread seasonal gene expression reveals annual differences in human immunity and physiology.

Dopico XC, Evangelou M, Ferreira RC, Guo H, Pekalski ML, Smyth DJ, Cooper N, Burren OS, Fulford AJ, Hennig BJ, Prentice AM, Ziegler AG, Bonifacio E, Wallace C, Todd JA.

Nat Commun. 2015 May 12;6:7000. doi: 10.1038/ncomms8000.

44.

Effective recruitment of participants to a phase I study using the internet and publicity releases through charities and patient organisations: analysis of the adaptive study of IL-2 dose on regulatory T cells in type 1 diabetes (DILT1D).

Heywood J, Evangelou M, Goymer D, Kennet J, Anselmiova K, Guy C, O'Brien C, Nutland S, Brown J, Walker NM, Todd JA, Waldron-Lynch F.

Trials. 2015 Mar 11;16:86. doi: 10.1186/s13063-015-0583-7.

45.

Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers.

Onengut-Gumuscu S, Chen WM, Burren O, Cooper NJ, Quinlan AR, Mychaleckyj JC, Farber E, Bonnie JK, Szpak M, Schofield E, Achuthan P, Guo H, Fortune MD, Stevens H, Walker NM, Ward LD, Kundaje A, Kellis M, Daly MJ, Barrett JC, Cooper JD, Deloukas P; Type 1 Diabetes Genetics Consortium, Todd JA, Wallace C, Concannon P, Rich SS.

Nat Genet. 2015 Apr;47(4):381-6. doi: 10.1038/ng.3245. Epub 2015 Mar 9.

46.

Integration of disease association and eQTL data using a Bayesian colocalisation approach highlights six candidate causal genes in immune-mediated diseases.

Guo H, Fortune MD, Burren OS, Schofield E, Todd JA, Wallace C.

Hum Mol Genet. 2015 Jun 15;24(12):3305-13. doi: 10.1093/hmg/ddv077. Epub 2015 Mar 5.

47.

IL-21 production by CD4+ effector T cells and frequency of circulating follicular helper T cells are increased in type 1 diabetes patients.

Ferreira RC, Simons HZ, Thompson WS, Cutler AJ, Dopico XC, Smyth DJ, Mashar M, Schuilenburg H, Walker NM, Dunger DB, Wallace C, Todd JA, Wicker LS, Pekalski ML.

Diabetologia. 2015 Apr;58(4):781-90. doi: 10.1007/s00125-015-3509-8. Epub 2015 Feb 6.

48.

A review of the Polystira clade--the Neotropic's largest marine gastropod radiation (Neogastropoda: Conoidea: Turridae sensu stricto).

Todd JA, Rawlings TA.

Zootaxa. 2014 Nov 18;3884(5):445-91. doi: 10.11646/zootaxa.3884.5.5.

PMID:
25543802
49.

Detection and correction of artefacts in estimation of rare copy number variants and analysis of rare deletions in type 1 diabetes.

Cooper NJ, Shtir CJ, Smyth DJ, Guo H, Swafford AD, Zanda M, Hurles ME, Walker NM, Plagnol V, Cooper JD, Howson JM, Burren OS, Onengut-Gumuscu S, Rich SS, Todd JA.

Hum Mol Genet. 2015 Mar 15;24(6):1774-90. doi: 10.1093/hmg/ddu581. Epub 2014 Nov 25.

50.

A method for gene-based pathway analysis using genomewide association study summary statistics reveals nine new type 1 diabetes associations.

Evangelou M, Smyth DJ, Fortune MD, Burren OS, Walker NM, Guo H, Onengut-Gumuscu S, Chen WM, Concannon P, Rich SS, Todd JA, Wallace C.

Genet Epidemiol. 2014 Dec;38(8):661-70. doi: 10.1002/gepi.21853. Epub 2014 Nov 4.

Supplemental Content

Support Center