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Items: 1 to 50 of 74

1.

Oral administration of the amino acids cystine and theanine attenuates the adverse events of S-1 adjuvant chemotherapy in gastrointestinal cancer patients.

Tsuchiya T, Honda H, Oikawa M, Kakita T, Oyama A, Oishi H, Tochikubo K, Hashimoto T, Kurihara S, Shibakusa T, Kayahara T.

Int J Clin Oncol. 2016 Dec;21(6):1085-1090. Epub 2016 Jun 15.

2.

Protective effect of nasal immunization of influenza virus hemagglutinin with recombinant cholera toxin B subunit as a mucosal adjuvant in mice.

Isaka M, Zhao Y, Nobusawa E, Nakajima S, Nakajima K, Yasuda Y, Matsui H, Hasegawa T, Maeyama J, Morokuma K, Ohkuma K, Tochikubo K.

Microbiol Immunol. 2008 Feb;52(2):55-63. doi: 10.1111/j.1348-0421.2008.00010.x.

3.

Absolute-length determination of a long-baseline Fabry-Perot cavity by means of resonating modulation sidebands.

Araya A, Telada S, Tochikubo K, Taniguchi S, Takahashi R, Kawabe K, Tatsumi D, Yamazaki T, Kawamura S, Miyoki S, Moriwaki S, Musha M, Nagano S, Fujimoto MK, Horikoshi K, Mio N, Naito Y, Takamori A, Yamamoto K.

Appl Opt. 1999 May 1;38(13):2848-56.

PMID:
18319865
4.

Induction of immune responses and prevention of alveolar bone loss by intranasal administration of mice with Porphyromonas gingivalis fimbriae and recombinant cholera toxin B subunit.

Takahashi Y, Kumada H, Hamada N, Haishima Y, Ozono S, Isaka M, Yasuda Y, Tochikubo K, Umemoto T.

Oral Microbiol Immunol. 2007 Dec;22(6):374-80.

PMID:
17949339
5.

Expression of Escherichia coli heat-labile enterotoxin B subunit (LTB) in Saccharomyces cerevisiae.

Rezaee MA, Rezaee A, Moazzeni SM, Salmanian AH, Yasuda Y, Tochikubo K, Pirayeh SN, Arzanlou M.

J Microbiol. 2005 Aug;43(4):354-60.

PMID:
16145550
6.

Recombinant cholera toxin B subunit activates dendritic cells and enhances antitumor immunity.

Isomura I, Yasuda Y, Tsujimura K, Takahashi T, Tochikubo K, Morita A.

Microbiol Immunol. 2005;49(1):79-87.

7.

Recombinant cholera toxin B subunit (rCTB) as a mucosal adjuvant enhances induction of diphtheria and tetanus antitoxin antibodies in mice by intranasal administration with diphtheria-pertussis-tetanus (DPT) combination vaccine.

Isaka M, Komiya T, Takahashi M, Yasuda Y, Taniguchi T, Zhao Y, Matano K, Matsui H, Maeyama J, Morokuma K, Ohkuma K, Goto N, Tochikubo K.

Vaccine. 2004 Aug 13;22(23-24):3061-8.

PMID:
15297056
8.
9.

Frequent nasal administrations of recombinant cholera toxin B subunit (rCTB)-containing tetanus and diphtheria toxoid vaccines induced antigen-specific serum and mucosal immune responses in the presence of anti-rCTB antibodies.

Yasuda Y, Isaka M, Taniguchi T, Zhao Y, Matano K, Matsui H, Morokuma K, Maeyama J, Ohkuma K, Goto N, Tochikubo K.

Vaccine. 2003 Jun 20;21(21-22):2954-63.

PMID:
12798639
10.

Mucosal and systemic antibody responses against an acellular pertussis vaccine in mice after intranasal co-administration with recombinant cholera toxin B subunit as an adjuvant.

Isaka M, Yasuda Y, Taniguchi T, Kozuka S, Matano K, Maeyama J, Morokuma K, Ohkuma K, Goto N, Tochikubo K.

Vaccine. 2003 Mar 7;21(11-12):1165-73.

PMID:
12559794
11.

Effects of recombinant cholera toxin B subunit on IL-1beta production by macrophages in vitro.

Maeyama J, Isaka M, Yasuda Y, Matano K, Taniguchi T, Morokuma K, Ohkuma K, Tochikubo K, Goto N.

Microbiol Immunol. 2002;46(9):593-9.

12.

Immune responses in mice to intranasal and intracutaneous administration of a DNA vaccine encoding Helicobacter pylori-catalase.

Miyashita M, Joh T, Watanabe K, Todoroki I, Seno K, Ohara H, Nomura T, Miyata M, Kasugai K, Tochikubo K, Itoh M, Nitta M.

Vaccine. 2002 May 22;20(17-18):2336-42.

PMID:
12009289
13.

Gene cluster for assembly of pilus colonization factor antigen III of enterotoxigenic Escherichia coli.

Taniguchi T, Akeda Y, Haba A, Yasuda Y, Yamamoto K, Honda T, Tochikubo K.

Infect Immun. 2001 Sep;69(9):5864-73.

14.

Development and clinical application of an immunoassay using intact Helicobacter pylori attached to a solid phase as an antigen.

Watanabe K, Joh T, Seno K, Sasaki M, Todoroki I, Miyashita M, Tochikubo K, Itoh M.

Clin Biochem. 2001 Jun;34(4):291-5.

PMID:
11440729
15.

Stable operation of a 300-m laser interferometer with sufficient sensitivity to detect gravitational-wave events within our galaxy.

Ando M, Arai K, Takahashi R, Heinzel G, Kawamura S, Tatsumi D, Kanda N, Tagoshi H, Araya A, Asada H, Aso Y, Barton MA, Fujimoto MK, Fukushima M, Futamase T, Hayama K, Horikoshi G, Ishizuka H, Kamikubota N, Kawabe K, Kawashima N, Kobayashi Y, Kojima Y, Kondo K, Kozai Y, Kuroda K, Matsuda N, Mio N, Miura K, Miyakawa O, Miyama SM, Miyoki S, Moriwaki S, Musha M, Nagano S, Nakagawa K, Nakamura T, Nakao K, Numata K, Ogawa Y, Ohashi M, Ohishi N, Okutomi S, Oohara K, Otsuka S, Saito Y, Sasaki M, Sato S, Sekiya A, Shibata M, Somiya K, Suzuki T, Takamori A, Tanaka T, Taniguchi S, Telada S, Tochikubo K, Tomaru T, Tsubono K, Tsuda N, Uchiyama T, Ueda A, Ueda K, Waseda K, Watanabe Y, Yakura H, Yamamoto K, Yamazaki T; TAMA Collaboration.

Phys Rev Lett. 2001 Apr 30;86(18):3950-4.

PMID:
11328068
16.

Cytokine responses to recombinant cholera toxin B subunit produced by Bacillus brevis as a mucosal adjuvant.

Maeyama J, Isaka M, Yasuda Y, Matano K, Kozuka S, Taniguchi T, Ohkuma K, Tochikubo K, Goto N.

Microbiol Immunol. 2001;45(2):111-7.

17.

Mucosal immunization against hepatitis B virus by intranasal co-administration of recombinant hepatitis B surface antigen and recombinant cholera toxin B subunit as an adjuvant.

Isaka M, Yasuda Y, Mizokami M, Kozuka S, Taniguchi T, Matano K, Maeyama J, Mizuno K, Morokuma K, Ohkuma K, Goto N, Tochikubo K.

Vaccine. 2001 Jan 8;19(11-12):1460-6.

PMID:
11163669
18.

Suppressive effects of DNA vaccines encoding heat shock protein on Helicobacter pylori-induced gastritis in mice.

Todoroki I, Joh T, Watanabe K, Miyashita M, Seno K, Nomura T, Ohara H, Yokoyama Y, Tochikubo K, Itoh M.

Biochem Biophys Res Commun. 2000 Oct 14;277(1):159-63.

PMID:
11027657
19.

Isozymic nature of spore coat-associated alanine racemase of Bacillus subtilis.

Kanda-Nambu K, Yasuda Y, Tochikubo K.

Amino Acids. 2000;18(4):375-87.

PMID:
10949920
20.

Safety evaluation of recombinant cholera toxin B subunit produced by Bacillus brevis as a mucosal adjuvant.

Goto N, Maeyama J, Yasuda Y, Isaka M, Matano K, Kozuka S, Taniguchi T, Miura Y, Ohkuma K, Tochikubo K.

Vaccine. 2000 Apr 14;18(20):2164-71.

PMID:
10715532
21.

Efficient extracellular production of recombinant Escherichia coli heat-labile enterotoxin B subunit by using the expression/secretion system of Bacillus brevis and its mucosal immunoadjuvanticity.

Kozuka S, Yasuda Y, Isaka M, Masaki N, Taniguchi T, Matano K, Moriyama A, Ohkuma K, Goto N, Udaka S, Tochikubo K.

Vaccine. 2000 Mar 6;18(17):1730-7.

PMID:
10699320
22.
23.

Induction of systemic and mucosal antibody responses in mice immunized intranasally with aluminium-non-adsorbed diphtheria toxoid together with recombinant cholera toxin B subunit as an adjuvant.

Isaka M, Yasuda Y, Kozuka S, Taniguchi T, Matano K, Maeyama J, Komiya T, Ohkuma K, Goto N, Tochikubo K.

Vaccine. 1999 Nov 12;18(7-8):743-51.

PMID:
10547435
24.

Injurious effect of Helicobacter pylori culture fluid to gastroduodenal mucosa, and its detoxification by sucralfate in the rat.

Watanabe K, Joh T, Seno K, Takahashi N, Ohara H, Nomura T, Tochikubo K, Itoh M.

Aliment Pharmacol Ther. 1999 Oct;13(10):1363-71.

25.

Expression of a germination-specific amidase, SleB, of Bacilli in the forespore compartment of sporulating cells and its localization on the exterior side of the cortex in dormant spores.

Moriyama R, Fukuoka H, Miyata S, Kudoh S, Hattori A, Kozuka S, Yasuda Y, Tochikubo K, Makino S.

J Bacteriol. 1999 Apr;181(8):2373-8.

26.

Intranasal or subcutaneous co-administration of recombinant cholera toxin B subunit stimulates only a slight or no level of the specific IgE response in mice to tetanus toxoid.

Isaka M, Yasuda Y, Kozuka S, Taniguchi T, Miura Y, Matano K, Goto N, Tochikubo K.

Vaccine. 1999 Feb 26;17(7-8):944-8.

PMID:
10067701
27.

Cloning of a novel gene yrbB, encoding a protein located in the spore integument of Bacillus subtilis.

Takamatsu H, Hiraoka T, Kodama T, Koide H, Kozuka S, Tochikubo K, Watabe K.

FEMS Microbiol Lett. 1998 Sep 15;166(2):361-7.

28.

Systemic and mucosal immune responses of mice to aluminium-adsorbed or aluminium-non-adsorbed tetanus toxoid administered intranasally with recombinant cholera toxin B subunit.

Isaka M, Yasuda Y, Kozuka S, Miura Y, Taniguchi T, Matano K, Goto N, Tochikubo K.

Vaccine. 1998 Oct;16(17):1620-6.

PMID:
9713937
29.
30.
31.

Recombinant cholera toxin B subunit acts as an adjuvant for the mucosal and systemic responses of mice to mucosally co-administered bovine serum albumin.

Tochikubo K, Isaka M, Yasuda Y, Kozuka S, Matano K, Miura Y, Taniguchi T.

Vaccine. 1998 Jan-Feb;16(2-3):150-5.

PMID:
9607023
32.

Localization of germination-specific spore-lytic enzymes in Clostridium perfringens S40 spores detected by immunoelectron microscopy.

Miyata S, Kozuka S, Yasuda Y, Chen Y, Moriyama R, Tochikubo K, Makino S.

FEMS Microbiol Lett. 1997 Jul 15;152(2):243-7.

33.

Expression and secretion of the S2 subunit of pertussis toxin in Bacillus brevis.

Kozuka S, Yasuda Y, Tochikubo K.

Vaccine. 1996 Dec;14(17-18):1707-11.

PMID:
9032903
34.

[Regulation of the phosphorelay at the initiation of sporulation and activation of sporulation-specific sigma factors in Bacillus subtilis].

Tochikubo K, Yasuda Y.

Nihon Saikingaku Zasshi. 1996 Aug;51(3):789-801. Review. Japanese. No abstract available.

PMID:
8840810
35.

Immunological detection of the GerA spore germination proteins in the spore integuments of Bacillus subtilis using scanning electron microscopy.

Yasuda Y, Sakae Y, Tochikubo K.

FEMS Microbiol Lett. 1996 Jun 1;139(2-3):235-8. Erratum in: FEMS Microbiol Lett 1996 Nov 1;144(2-3):277-8.

PMID:
8674993
36.

Permeability of dormant spores of Bacillus subtilis to gramicidin S.

Tanimoto Y, Ichikawa Y, Yasuda Y, Tochikubo K.

FEMS Microbiol Lett. 1996 Feb 15;136(2):151-6.

PMID:
8869499
37.

Role of fimbriae in adherence of Streptococcus pyogenes to pharyngeal epithelial cells.

Kasashima T, Suzuki K, Miyamoto N, Baba S, Tochikubo K.

Acta Otolaryngol Suppl. 1996;525:40-3.

PMID:
8908268
38.
39.

Very efficient extracellular production of cholera toxin B subunit using Bacillus brevis.

Ichikawa Y, Yamagata H, Tochikubo K, Udaka S.

FEMS Microbiol Lett. 1993 Aug 1;111(2-3):219-24.

PMID:
8405930
40.

Evidence that dipicolinic acid is covalently bound to specific macromolecules in spores of Bacillus subtilis.

Matano Y, Yasuda Y, Tochikubo K.

FEMS Microbiol Lett. 1993 May 15;109(2-3):189-94. Erratum in: FEMS Microbiol Lett 1993 Sep 15;112(3):353.

PMID:
8339911
41.

Regulation of L-alanine-initiated germination ofBacillus subtilis spores by alanine racemase.

Yasuda Y, Kanda K, Nishioka S, Tanimoto Y, Kato C, Saito A, Fukuchi S, Nakanishi Y, Tochikubo K.

Amino Acids. 1993 Feb;4(1-2):89-99. doi: 10.1007/BF00805804.

PMID:
24190560
43.

Permeability of dormant spores of Bacillus subtilis to malachite green and crystal violet.

Kozuka S, Tochikubo K.

J Gen Microbiol. 1991 Mar;137(3):607-13.

PMID:
1903433
44.

Permeability of gentamicin and polymyxin B into the inside of Bacillus subtilis spores.

Fujita Y, Yasuda Y, Tochikubo K.

Microbiol Immunol. 1990;34(12):1013-23.

45.

Presence of proteins derived from the vegetative cell membrane in the dormant spore coat of Bacillus subtilis.

Fujita Y, Yasuda Y, Kozuka S, Tochikubo K.

Microbiol Immunol. 1989;33(5):391-401.

46.

[A case of Hartnup disease].

Orihara T, Tochikubo K, Tsuchiya K, Furuya T.

Nihon Hifuka Gakkai Zasshi. 1988 Jan;98(1):21-6. Japanese. No abstract available.

PMID:
2969989
47.

Inhibitory action of dipicolinic acid on the activation of inactive glucose dehydrogenase from Bacillus subtilis spores.

Tochikubo K, Yasuda Y, Kozuka S.

Microbiol Immunol. 1987;31(1):95-100. No abstract available.

48.

Decreased particulate NADH oxidase activity in Bacillus subtilis spores after polymyxin B treatment.

Tochikubo K, Yasuda Y, Kozuka S.

J Gen Microbiol. 1986 Feb;132(2):277-87.

PMID:
3011961
50.

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