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Dopaminergic D1 Receptor Stimulation Affects Effort and Risk Preferences.

Soutschek A, Gvozdanovic G, Kozak R, Duvvuri S, de Martinis N, Harel B, Gray DL, Fehr E, Jetter A, Tobler PN.

Biol Psychiatry. 2019 Sep 12. pii: S0006-3223(19)31670-1. doi: 10.1016/j.biopsych.2019.09.002. [Epub ahead of print]


Testosterone administration increases social discounting in healthy males.

Wu Y, Liao J, Zilioli S, Wu Y, Deng H, Li H, Tobler PN.

Psychoneuroendocrinology. 2019 Oct;108:127-134. doi: 10.1016/j.psyneuen.2019.06.013. Epub 2019 Jun 26.


Traffic Lights Intervention Reduces Therapeutic Inertia: A Randomized Controlled Trial in Multiple Sclerosis Care.

Saposnik G, Mamdani M, Montalban X, Terzaghi M, Silva B, Saladino ML, Tobler PN, Caceres F.

MDM Policy Pract. 2019 Jun 21;4(1):2381468319855642. doi: 10.1177/2381468319855642. eCollection 2019 Jan-Jun.


Emotional expressions associated with therapeutic inertia in multiple sclerosis care.

Saposnik G, Oh J, Terzaghi MA, Kostyrko P, Bakdache F, Montoya A, Jaja BNR, Nisenbaum R, Ruff CC, Tobler PN.

Mult Scler Relat Disord. 2019 Sep;34:17-28. doi: 10.1016/j.msard.2019.05.029. Epub 2019 Jun 4.


Incidental ostracism emerges from simple learning mechanisms.

Lindström B, Tobler PN.

Nat Hum Behav. 2018 Jun;2(6):405-414. doi: 10.1038/s41562-018-0355-y. Epub 2018 May 28.


Shared and dissociable features of apathy and reward system dysfunction in bipolar I disorder and schizophrenia.

Kirschner M, Cathomas F, Manoliu A, Habermeyer B, Simon JJ, Seifritz E, Tobler PN, Kaiser S.

Psychol Med. 2019 Apr 17:1-12. doi: 10.1017/S0033291719000801. [Epub ahead of print]


Social threat learning transfers to decision making in humans.

Lindström B, Golkar A, Jangard S, Tobler PN, Olsson A.

Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4732-4737. doi: 10.1073/pnas.1810180116. Epub 2019 Feb 13.


The Role of Prescribing Generic (Non-proprietary) Drugs in the Prevalence of Therapeutic Inertia in Multiple Sclerosis Care.

Saposnik G, Mamdani M, Terzaghi M, Saladino ML, Silva B, Tobler PN, Caceres F.

Front Neurol. 2018 Oct 12;9:835. doi: 10.3389/fneur.2018.00835. eCollection 2018.


Frontostriatal pathways gate processing of behaviorally relevant reward dimensions.

Weber SC, Kahnt T, Quednow BB, Tobler PN.

PLoS Biol. 2018 Oct 19;16(10):e2005722. doi: 10.1371/journal.pbio.2005722. eCollection 2018 Oct.


Pain relief provided by an outgroup member enhances analgesia.

Hein G, Engelmann JB, Tobler PN.

Proc Biol Sci. 2018 Sep 26;285(1887). pii: 20180501. doi: 10.1098/rspb.2018.0501.


Cerebral blood flow in striatal regions is associated with apathy in patients with schizophrenia.

Schneider K, Michels L, Hartmann-Riemer MN, Burrer A, Tobler PN, Stämpfli P, Kirschner M, Seifritz E, Kaiser S.

J Psychiatry Neurosci. 2019 Mar 1;44(2):102-110. doi: 10.1503/jpn.170150.


Deficits in context-dependent adaptive coding in early psychosis and healthy individuals with schizotypal personality traits.

Kirschner M, Haugg A, Manoliu A, Simon JJ, Huys QJM, Seifritz E, Tobler PN, Kaiser S.

Brain. 2018 Sep 1;141(9):2806-2819. doi: 10.1093/brain/awy203.


Usability of an Educational Intervention to Overcome Therapeutic Inertia in Multiple Sclerosis Care.

Saposnik G, Tobler PN, Caceres F, Terzaghi MA, Ruff C, Maurino J, Fruns Quintana M, Oh J, Montalban X, Mamdani M.

Front Neurol. 2018 Jul 10;9:522. doi: 10.3389/fneur.2018.00522. eCollection 2018.


Investigating the association of ventral and dorsal striatal dysfunction during reward anticipation with negative symptoms in patients with schizophrenia and healthy individuals.

Stepien M, Manoliu A, Kubli R, Schneider K, Tobler PN, Seifritz E, Herdener M, Kaiser S, Kirschner M.

PLoS One. 2018 Jun 18;13(6):e0198215. doi: 10.1371/journal.pone.0198215. eCollection 2018.


Inequality signals in dorsolateral prefrontal cortex inform social preference models.

Holper L, Burke CJ, Fausch C, Seifritz E, Tobler PN.

Soc Cogn Affect Neurosci. 2018 May 1;13(5):513-524. doi: 10.1093/scan/nsy020.


Brain Stimulation Over the Frontopolar Cortex Enhances Motivation to Exert Effort for Reward.

Soutschek A, Kang P, Ruff CC, Hare TA, Tobler PN.

Biol Psychiatry. 2018 Jul 1;84(1):38-45. doi: 10.1016/j.biopsych.2017.11.007. Epub 2017 Dec 22.


Dopamine Receptor-Specific Contributions to the Computation of Value.

Burke CJ, Soutschek A, Weber S, Raja Beharelle A, Fehr E, Haker H, Tobler PN.

Neuropsychopharmacology. 2018 May;43(6):1415-1424. doi: 10.1038/npp.2017.302. Epub 2017 Dec 18.


Timed function tests, motor function measure, and quantitative thigh muscle MRI in ambulant children with Duchenne muscular dystrophy: A cross-sectional analysis.

Schmidt S, Hafner P, Klein A, Rubino-Nacht D, Gocheva V, Schroeder J, Naduvilekoot Devasia A, Zuesli S, Bernert G, Laugel V, Bloetzer C, Steinlin M, Capone A, Gloor M, Tobler P, Haas T, Bieri O, Zumbrunn T, Fischer D, Bonati U.

Neuromuscul Disord. 2018 Jan;28(1):16-23. doi: 10.1016/j.nmd.2017.10.003. Epub 2017 Nov 21.


Ventrolateral Prefrontal Cortex Updates Chosen Value According to Choice Set Size.

Fujiwara J, Usui N, Eifuku S, Iijima T, Taira M, Tsutsui KI, Tobler PN.

J Cogn Neurosci. 2018 Mar;30(3):307-318. doi: 10.1162/jocn_a_01207. Epub 2017 Nov 13.


The dopaminergic reward system underpins gender differences in social preferences.

Soutschek A, Burke CJ, Raja Beharelle A, Schreiber R, Weber SC, Karipidis II, Ten Velden J, Weber B, Haker H, Kalenscher T, Tobler PN.

Nat Hum Behav. 2017 Nov;1(11):819-827. doi: 10.1038/s41562-017-0226-y. Epub 2017 Oct 9.


Overcoming Therapeutic Inertia in Multiple Sclerosis Care: A Pilot Randomized Trial Applying the Traffic Light System in Medical Education.

Saposnik G, Maurino J, Sempere AP, Terzaghi MA, Ruff CC, Mamdani M, Tobler PN, Montalban X.

Front Neurol. 2017 Aug 21;8:430. doi: 10.3389/fneur.2017.00430. eCollection 2017.


A neural link between generosity and happiness.

Park SQ, Kahnt T, Dogan A, Strang S, Fehr E, Tobler PN.

Nat Commun. 2017 Jul 11;8:15964. doi: 10.1038/ncomms15964.


Adaptive Value Normalization in the Prefrontal Cortex Is Reduced by Memory Load.

Holper L, Van Brussel LD, Schmidt L, Schulthess S, Burke CJ, Louie K, Seifritz E, Tobler PN.

eNeuro. 2017 Apr 27;4(2). pii: ENEURO.0365-17.2017. doi: 10.1523/ENEURO.0365-17.2017. eCollection 2017 Mar-Apr.


Corrigendum: Deficits in reinforcement learning but no link to apathy in patients with schizophrenia.

Hartmann-Riemer MN, Aschenbrenner S, Bossert M, Westermann C, Seifritz E, Tobler PN, Weisbrod M, Kaiser S.

Sci Rep. 2017 Apr 11;7:44510. doi: 10.1038/srep44510. No abstract available.


Ovarian hormones and obesity.

Leeners B, Geary N, Tobler PN, Asarian L.

Hum Reprod Update. 2017 May 1;23(3):300-321. doi: 10.1093/humupd/dmw045. Review.


Decision-making in Multiple Sclerosis: The Role of Aversion to Ambiguity for Therapeutic Inertia among Neurologists (DIScUTIR MS).

Saposnik G, Sempere AP, Prefasi D, Selchen D, Ruff CC, Maurino J, Tobler PN.

Front Neurol. 2017 Mar 1;8:65. doi: 10.3389/fneur.2017.00065. eCollection 2017.


Herding: a new phenomenon affecting medical decision-making in multiple sclerosis care? Lessons learned from DIScUTIR MS.

Saposnik G, Maurino J, Sempere AP, Ruff CC, Tobler PN.

Patient Prefer Adherence. 2017 Jan 31;11:175-180. doi: 10.2147/PPA.S124192. eCollection 2017.


Binding oneself to the mast: stimulating frontopolar cortex enhances precommitment.

Soutschek A, Ugazio G, Crockett MJ, Ruff CC, Kalenscher T, Tobler PN.

Soc Cogn Affect Neurosci. 2017 Apr 1;12(4):635-642. doi: 10.1093/scan/nsw176.


Altered reward anticipation: Potential explanation for weight gain in schizophrenia?

Grimm O, Kaiser S, Plichta MM, Tobler PN.

Neurosci Biobehav Rev. 2017 Apr;75:91-103. doi: 10.1016/j.neubiorev.2017.01.029. Epub 2017 Jan 29. Review.


Deficits in reinforcement learning but no link to apathy in patients with schizophrenia.

Hartmann-Riemer MN, Aschenbrenner S, Bossert M, Westermann C, Seifritz E, Tobler PN, Weisbrod M, Kaiser S.

Sci Rep. 2017 Jan 10;7:40352. doi: 10.1038/srep40352. Erratum in: Sci Rep. 2017 Apr 11;7:44510.


Dopamine Modulates the Functional Organization of the Orbitofrontal Cortex.

Kahnt T, Tobler PN.

J Neurosci. 2017 Feb 8;37(6):1493-1504. doi: 10.1523/JNEUROSCI.2827-16.2016. Epub 2017 Jan 9.


Cognitive biases associated with medical decisions: a systematic review.

Saposnik G, Redelmeier D, Ruff CC, Tobler PN.

BMC Med Inform Decis Mak. 2016 Nov 3;16(1):138. Review.


Testosterone administration does not affect men's rejections of low ultimatum game offers or aggressive mood.

Cueva C, Roberts RE, Spencer TJ, Rani N, Tempest M, Tobler PN, Herbert J, Rustichini A.

Horm Behav. 2017 Jan;87:1-7. doi: 10.1016/j.yhbeh.2016.09.012. Epub 2016 Oct 3.


Ventral Striatal Dysfunction and Symptom Expression in Individuals With Schizotypal Personality Traits and Early Psychosis.

Kirschner M, Hager OM, Muff L, Bischof M, Hartmann-Riemer MN, Kluge A, Habermeyer B, Seifritz E, Tobler PN, Kaiser S.

Schizophr Bull. 2018 Jan 13;44(1):147-157. doi: 10.1093/schbul/sbw142.


Brain stimulation reveals crucial role of overcoming self-centeredness in self-control.

Soutschek A, Ruff CC, Strombach T, Kalenscher T, Tobler PN.

Sci Adv. 2016 Oct 19;2(10):e1600992. eCollection 2016 Oct.


Partial Adaptation of Obtained and Observed Value Signals Preserves Information about Gains and Losses.

Burke CJ, Baddeley M, Tobler PN, Schultz W.

J Neurosci. 2016 Sep 28;36(39):10016-25. doi: 10.1523/JNEUROSCI.0487-16.2016. Epub 2016 Sep 28.


Prefrontal connections express individual differences in intrinsic resistance to trading off honesty values against economic benefits.

Dogan A, Morishima Y, Heise F, Tanner C, Gibson R, Wagner AF, Tobler PN.

Sci Rep. 2016 Sep 20;6:33263. doi: 10.1038/srep33263.


Deficits in context-dependent adaptive coding of reward in schizophrenia.

Kirschner M, Hager OM, Bischof M, Hartmann-Riemer MN, Kluge A, Seifritz E, Tobler PN, Kaiser S.

NPJ Schizophr. 2016 Jun 15;2:16020. doi: 10.1038/npjschz.2016.20. eCollection 2016.


Time, Not Size, Matters for Striatal Reward Predictions to Dopamine.

Burke CJ, Tobler PN.

Neuron. 2016 Jul 6;91(1):8-11. doi: 10.1016/j.neuron.2016.06.029. Review.


Doubt in the Insula: Risk Processing in Obsessive-Compulsive Disorder.

Luigjes J, Figee M, Tobler PN, van den Brink W, de Kwaasteniet B, van Wingen G, Denys D.

Front Hum Neurosci. 2016 Jun 14;10:283. doi: 10.3389/fnhum.2016.00283. eCollection 2016.


Dopamine D2/3- and μ-opioid receptor antagonists reduce cue-induced responding and reward impulsivity in humans.

Weber SC, Beck-Schimmer B, Kajdi ME, Müller D, Tobler PN, Quednow BB.

Transl Psychiatry. 2016 Jul 5;6(7):e850. doi: 10.1038/tp.2016.113.


Ventral Pallidum Encodes Contextual Information and Controls Aversive Behaviors.

Saga Y, Richard A, Sgambato-Faure V, Hoshi E, Tobler PN, Tremblay L.

Cereb Cortex. 2017 Apr 1;27(4):2528-2543. doi: 10.1093/cercor/bhw107.


Shared neural basis of social and non-social reward deficits in chronic cocaine users.

Tobler PN, Preller KH, Campbell-Meiklejohn DK, Kirschner M, Kraehenmann R, Stämpfli P, Herdener M, Seifritz E, Quednow BB.

Soc Cogn Affect Neurosci. 2016 Jun;11(6):1017-25. doi: 10.1093/scan/nsw030. Epub 2016 Mar 12.


Dopamine regulates stimulus generalization in the human hippocampus.

Kahnt T, Tobler PN.

Elife. 2016 Feb 2;5:e12678. doi: 10.7554/eLife.12678.


How learning shapes the empathic brain.

Hein G, Engelmann JB, Vollberg MC, Tobler PN.

Proc Natl Acad Sci U S A. 2016 Jan 5;113(1):80-5. doi: 10.1073/pnas.1514539112. Epub 2015 Dec 22.


Ventral striatal hypoactivation is associated with apathy but not diminished expression in patients with schizophrenia.

Kirschner M, Hager OM, Bischof M, Hartmann MN, Kluge A, Seifritz E, Tobler PN, Kaiser S.

J Psychiatry Neurosci. 2016 Apr;41(3):152-61. Erratum in: J Psychiatry Neurosci. 2017 Mar;42(2):102.


Discrete coding of stimulus value, reward expectation, and reward prediction error in the dorsal striatum.

Oyama K, Tateyama Y, Hernádi I, Tobler PN, Iijima T, Tsutsui K.

J Neurophysiol. 2015 Nov;114(5):2600-15. doi: 10.1152/jn.00097.2015. Epub 2015 Sep 16.


Reward-dependent modulation of working memory is associated with negative symptoms in schizophrenia.

Hager OM, Kirschner M, Bischof M, Hartmann-Riemer MN, Kluge A, Seifritz E, Tobler PN, Kaiser S.

Schizophr Res. 2015 Oct;168(1-2):238-44. doi: 10.1016/j.schres.2015.08.024. Epub 2015 Sep 9.


Cortisol and testosterone increase financial risk taking and may destabilize markets.

Cueva C, Roberts RE, Spencer T, Rani N, Tempest M, Tobler PN, Herbert J, Rustichini A.

Sci Rep. 2015 Jul 2;5:11206. doi: 10.1038/srep11206.


Spatial gradient in value representation along the medial prefrontal cortex reflects individual differences in prosociality.

Sul S, Tobler PN, Hein G, Leiberg S, Jung D, Fehr E, Kim H.

Proc Natl Acad Sci U S A. 2015 Jun 23;112(25):7851-6. doi: 10.1073/pnas.1423895112. Epub 2015 Jun 8.

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