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Fine-mapping of genetic loci driving spontaneous clearance of hepatitis C virus infection.

Huang H, Duggal P, Thio CL, Latanich R, Goedert JJ, Mangia A, Cox AL, Kirk GD, Mehta S, Aneja J, Alric L, Donfield SM, Cramp ME, Khakoo SI, Tobler LH, Busch M, Alexander GJ, Rosen HR, Edlin BR, Segal FP, Lauer GM, Thomas DL, Daly MJ, Chung RT, Kim AY.

Sci Rep. 2017 Nov 20;7(1):15843. doi: 10.1038/s41598-017-16011-2.


A 320 Year Ice-Core Record of Atmospheric Hg Pollution in the Altai, Central Asia.

Eyrikh S, Eichler A, Tobler L, Malygina N, Papina T, Schwikowski M.

Environ Sci Technol. 2017 Oct 17;51(20):11597-11606. doi: 10.1021/acs.est.7b03140. Epub 2017 Oct 3.


Ice-core evidence of earliest extensive copper metallurgy in the Andes 2700 years ago.

Eichler A, Gramlich G, Kellerhals T, Tobler L, Rehren T, Schwikowski M.

Sci Rep. 2017 Jan 31;7:41855. doi: 10.1038/srep41855.


Pb pollution from leaded gasoline in South America in the context of a 2000-year metallurgical history.

Eichler A, Gramlich G, Kellerhals T, Tobler L, Schwikowski M.

Sci Adv. 2015 Mar 6;1(2):e1400196. doi: 10.1126/sciadv.1400196. eCollection 2015 Mar.


Reducing state employee health insurance costs.

Tobler L.

NCSL Legisbrief. 2014 Oct;22(39):1-2.


A closer look at hepatitis C clearance in HIV controllers: a response.

Asher AK, Santos GM, Evans J, Dokubo EK, Lee TH, Martin JN, Deeks SG, Tobler LH, Busch M, Hunt PW, Page K.

AIDS. 2014 May 15;28(8):1241-2. doi: 10.1097/QAD.0000000000000208. No abstract available.


West Nile virus nucleic acid persistence in whole blood months after clearance in plasma: implication for transfusion and transplantation safety.

Lanteri MC, Lee TH, Wen L, Kaidarova Z, Bravo MD, Kiely NE, Kamel HT, Tobler LH, Norris PJ, Busch MP.

Transfusion. 2014 Dec;54(12):3232-41. doi: 10.1111/trf.12764. Epub 2014 Jun 26.


Providing health care coverage for former inmates.

Tobler L.

NCSL Legisbrief. 2014 Apr;22(15):1-2.


Treating the whole person by integrating care.

Tobler L, Edmonds C.

NCSL Legisbrief. 2013 Dec;21(47):1-2. No abstract available.


Comparison of Hepatitis C Virus RNA and antibody detection in dried blood spots and plasma specimens.

Dokubo EK, Evans J, Winkelman V, Cyrus S, Tobler LH, Asher A, Briceno A, Page K.

J Clin Virol. 2014 Apr;59(4):223-7. doi: 10.1016/j.jcv.2014.01.014. Epub 2014 Jan 27.


Ice-core based assessment of historical anthropogenic heavy metal (Cd, Cu, Sb, Zn) emissions in the Soviet Union.

Eichler A, Tobler L, Eyrikh S, Malygina N, Papina T, Schwikowski M.

Environ Sci Technol. 2014;48(5):2635-42. doi: 10.1021/es404861n. Epub 2014 Feb 18.


Development of a contemporary globally diverse HIV viral panel by the EQAPOL program.

Sanchez AM, DeMarco CT, Hora B, Keinonen S, Chen Y, Brinkley C, Stone M, Tobler L, Keating S, Schito M, Busch MP, Gao F, Denny TN.

J Immunol Methods. 2014 Jul;409:117-30. doi: 10.1016/j.jim.2014.01.004. Epub 2014 Jan 19.


Characteristics of antibody responses in West Nile virus-seropositive blood donors.

Carson PJ, Prince HE, Biggerstaff BJ, Lanciotti R, Tobler LH, Busch M.

J Clin Microbiol. 2014 Jan;52(1):57-60. doi: 10.1128/JCM.01932-13. Epub 2013 Oct 16.


Human leukocyte antigen B*57 does not fully explain hepatitis C clearance in HIV controllers.

Asher AK, Santos GM, Evans J, Dokubo EK, Lee TH, Martin JN, Deeks SG, Tobler LH, Busch M, Hunt PW, Page K.

AIDS. 2013 Nov 13;27(17):2691-6. doi: 10.1097/01.aids.0000433242.86362.21. Erratum in: AIDS. 2014 Feb 20;28(4):619.


Bridging the health divide: community health workers are helping eliminate costly health inequalities.

Tobler L.

State Legis. 2013 Jun;39(6):24-5. No abstract available.


Reducing correctional health care spending.

Tobler L, Goodwin K.

NCSL Legisbrief. 2013 Mar;21(10):1-2. No abstract available.


Genome-wide association study of spontaneous resolution of hepatitis C virus infection: data from multiple cohorts.

Duggal P, Thio CL, Wojcik GL, Goedert JJ, Mangia A, Latanich R, Kim AY, Lauer GM, Chung RT, Peters MG, Kirk GD, Mehta SH, Cox AL, Khakoo SI, Alric L, Cramp ME, Donfield SM, Edlin BR, Tobler LH, Busch MP, Alexander G, Rosen HR, Gao X, Abdel-Hamid M, Apps R, Carrington M, Thomas DL.

Ann Intern Med. 2013 Feb 19;158(4):235-45. doi: 10.7326/0003-4819-158-4-201302190-00003.


Frequent longitudinal sampling of hepatitis C virus infection in injection drug users reveals intermittently detectable viremia and reinfection.

Page K, Osburn W, Evans J, Hahn JA, Lum P, Asher A, Delwart E, Tobler L, Cox AL, Busch MP.

Clin Infect Dis. 2013 Feb;56(3):405-13. doi: 10.1093/cid/cis921. Epub 2012 Oct 22.


Neuroinvasive disease and West Nile virus infection, North Dakota, USA, 1999-2008.

Carson PJ, Borchardt SM, Custer B, Prince HE, Dunn-Williams J, Winkelman V, Tobler L, Biggerstaff BJ, Lanciotti R, Petersen LR, Busch MP.

Emerg Infect Dis. 2012 Apr;18(4):684-6. doi: 10.3201/eid1804.111313.


Distinct roles of trauma and transfusion in induction of immune modulation after injury.

Jackman RP, Utter GH, Muench MO, Heitman JW, Munz MM, Jackman RW, Biswas HH, Rivers RM, Tobler LH, Busch MP, Norris PJ.

Transfusion. 2012 Dec;52(12):2533-50. doi: 10.1111/j.1537-2995.2012.03618.x. Epub 2012 Mar 27.


Three centuries of Eastern European and Altai lead emissions recorded in a Belukha ice core.

Eichler A, Tobler L, Eyrikh S, Gramlich G, Malygina N, Papina T, Schwikowski M.

Environ Sci Technol. 2012 Apr 17;46(8):4323-30. doi: 10.1021/es2039954. Epub 2012 Mar 26.


Epidemiologic and laboratory findings from 3 years of testing United States blood donors for Trypanosoma cruzi.

Custer B, Agapova M, Bruhn R, Cusick R, Kamel H, Tomasulo P, Biswas H, Tobler L, Lee TH, Caglioti S, Busch M.

Transfusion. 2012 Sep;52(9):1901-11. doi: 10.1111/j.1537-2995.2012.03569.x. Epub 2012 Feb 17.


Genetic diversity of recently acquired and prevalent HIV, hepatitis B virus, and hepatitis C virus infections in US blood donors.

Delwart E, Slikas E, Stramer SL, Kamel H, Kessler D, Krysztof D, Tobler LH, Carrick DM, Steele W, Todd D, Wright DJ, Kleinman SH, Busch MP; NHLBI-REDS-II Study Group.

J Infect Dis. 2012 Mar 15;205(6):875-85. doi: 10.1093/infdis/jir862. Epub 2012 Jan 31.


A solid phase extraction-liquid chromatographic-tandem mass spectrometry method for determination of concentrations of GDC-0941, a small molecule class I phosphatidylinositide 3-kinase inhibitor, to support clinical development.

Ding X, Morrison G, Dean B, Hop CE, Tobler L, Percey S, Meng M, Reuschel S, West DA, Holden S, Ware JA.

J Pharm Biomed Anal. 2012 Mar 5;61:1-7. doi: 10.1016/j.jpba.2011.11.005. Epub 2011 Nov 25.


Iron deficiency in blood donors: the REDS-II Donor Iron Status Evaluation (RISE) study.

Cable RG, Glynn SA, Kiss JE, Mast AE, Steele WR, Murphy EL, Wright DJ, Sacher RA, Gottschall JL, Tobler LH, Simon TL; NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II).

Transfusion. 2012 Apr;52(4):702-11. doi: 10.1111/j.1537-2995.2011.03401.x. Epub 2011 Oct 24.


Failure to confirm XMRV/MLVs in the blood of patients with chronic fatigue syndrome: a multi-laboratory study.

Simmons G, Glynn SA, Komaroff AL, Mikovits JA, Tobler LH, Hackett J Jr, Tang N, Switzer WM, Heneine W, Hewlett IK, Zhao J, Lo SC, Alter HJ, Linnen JM, Gao K, Coffin JM, Kearney MF, Ruscetti FW, Pfost MA, Bethel J, Kleinman S, Holmberg JA, Busch MP; Blood XMRV Scientific Research Working Group (SRWG).

Science. 2011 Nov 11;334(6057):814-7. doi: 10.1126/science.1213841. Epub 2011 Sep 22.


Association between HLA class I and class II alleles and the outcome of West Nile virus infection: an exploratory study.

Lanteri MC, Kaidarova Z, Peterson T, Cate S, Custer B, Wu S, Agapova M, Law JP, Bielawny T, Plummer F, Tobler LH, Loeb M, Busch MP, Bramson J, Luo M, Norris PJ.

PLoS One. 2011;6(8):e22948. doi: 10.1371/journal.pone.0022948. Epub 2011 Aug 1.


Relative distribution of West Nile virus RNA in blood compartments: implications for blood donor nucleic acid amplification technology screening.

Lai L, Lee TH, Tobler L, Wen L, Shi P, Alexander J, Ewing H, Busch M.

Transfusion. 2012 Feb;52(2):447-54. doi: 10.1111/j.1537-2995.2011.03289.x. Epub 2011 Aug 9.


Patient-care practices associated with an increased prevalence of hepatitis C virus infection among chronic hemodialysis patients.

Shimokura G, Chai F, Weber DJ, Samsa GP, Xia GL, Nainan OV, Tobler LH, Busch MP, Alter MJ.

Infect Control Hosp Epidemiol. 2011 May;32(5):415-24. doi: 10.1086/659407.


Distribution of parvovirus B19 DNA in blood compartments and persistence of virus in blood donors.

Lee TH, Kleinman SH, Wen L, Montalvo L, Todd DS, Wright DJ, Tobler LH, Busch MP; NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II).

Transfusion. 2011 Sep;51(9):1896-908. doi: 10.1111/j.1537-2995.2010.03035.x. Epub 2011 Feb 8.


A primary problem: more patients under federal health reform with fewer primary care doctors spell trouble.

Tobler L.

State Legis. 2010 Dec;36(10):20-4. No abstract available.


Induction of CXCR3- and CCR5-associated chemokines during acute hepatitis C virus infection.

Zeremski M, Hooker G, Shu MA, Winkelstein E, Brown Q, Des Jarlais DC, Tobler LH, Rehermann B, Busch MP, Edlin BR, Talal AH.

J Hepatol. 2011 Sep;55(3):545-553. doi: 10.1016/j.jhep.2010.12.033. Epub 2011 Jan 21.


Planning for end-of-life care.

Tobler L.

NCSL Legisbrief. 2010 Aug-Sep;18(34):1-2. No abstract available.


Host genetic basis for hepatitis C virus clearance: a role for blood collection centers.

Selvarajah S, Tobler LH, Simmons G, Busch MP.

Curr Opin Hematol. 2010 Nov;17(6):550-7. doi: 10.1097/MOH.0b013e32833e7544. Review.


A case-control study of factors associated with resolution of hepatitis C viremia in former blood donors (CME).

Tobler LH, Bahrami SH, Kaidarova Z, Pitina L, Winkelman VK, Vanderpool SK, Guiltinan AM, Cooper S, Busch MP, Murphy EL.

Transfusion. 2010 Jul;50(7):1513-23. doi: 10.1111/j.1537-2995.2010.02634.x. Epub 2010 Mar 25.


Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus.

Mosbruger TL, Duggal P, Goedert JJ, Kirk GD, Hoots WK, Tobler LH, Busch M, Peters MG, Rosen HR, Thomas DL, Thio CL.

J Infect Dis. 2010 May 1;201(9):1371-80. doi: 10.1086/651606.


Community health centers in the economic downturn.

Saenz M, Tobler L.

NCSL Legisbrief. 2010 Jan;18(5):1-2. No abstract available.


Thallium as a tracer for preindustrial volcanic eruptions in an ice core record from Illimani, Bolivia.

Kellerhals T, Tobler L, Brütsch S, Sigl M, Wacker L, Gäggeler HW, Schwikowski M.

Environ Sci Technol. 2010 Feb 1;44(3):888-93. doi: 10.1021/es902492n.


Tregs control the development of symptomatic West Nile virus infection in humans and mice.

Lanteri MC, O'Brien KM, Purtha WE, Cameron MJ, Lund JM, Owen RE, Heitman JW, Custer B, Hirschkorn DF, Tobler LH, Kiely N, Prince HE, Ndhlovu LC, Nixon DF, Kamel HT, Kelvin DJ, Busch MP, Rudensky AY, Diamond MS, Norris PJ.

J Clin Invest. 2009 Nov;119(11):3266-77. doi: 10.1172/JCI39387. Epub 2009 Oct 12.


Acute hepatitis C virus infection in young adult injection drug users: a prospective study of incident infection, resolution, and reinfection.

Page K, Hahn JA, Evans J, Shiboski S, Lum P, Delwart E, Tobler L, Andrews W, Avanesyan L, Cooper S, Busch MP.

J Infect Dis. 2009 Oct 15;200(8):1216-26. doi: 10.1086/605947.


Genetic variation in IL28B and spontaneous clearance of hepatitis C virus.

Thomas DL, Thio CL, Martin MP, Qi Y, Ge D, O'Huigin C, Kidd J, Kidd K, Khakoo SI, Alexander G, Goedert JJ, Kirk GD, Donfield SM, Rosen HR, Tobler LH, Busch MP, McHutchison JG, Goldstein DB, Carrington M.

Nature. 2009 Oct 8;461(7265):798-801. doi: 10.1038/nature08463.


A linked donor-recipient study to evaluate parvovirus B19 transmission by blood component transfusion.

Kleinman SH, Glynn SA, Lee TH, Tobler LH, Schlumpf KS, Todd DS, Qiao H, Yu MY, Busch MP; National Heart, Lung, and Blood Institute Retrovirus Epidemiology Donor Study-II (NHLBI REDS-II).

Blood. 2009 Oct 22;114(17):3677-83. doi: 10.1182/blood-2009-06-225706. Epub 2009 Aug 17.


More rare birds, and the occasional swan.

Edlin BR, Shu MA, Winkelstein E, Des Jarlais DC, Busch MP, Rehermann B, O'Brien TR, Talal AH, Tobler LH, Zeremski M, Beeder AB.

Gastroenterology. 2009 Jun;136(7):2412-4. doi: 10.1053/j.gastro.2009.04.040. Epub 2009 May 3. No abstract available.


Community health centers.

Hansen M, Tobler L.

NCSL Legisbrief. 2009 Jan;17(5):1-2. No abstract available.


Virus and antibody dynamics in acute west nile virus infection.

Busch MP, Kleinman SH, Tobler LH, Kamel HT, Norris PJ, Walsh I, Matud JL, Prince HE, Lanciotti RS, Wright DJ, Linnen JM, Caglioti S.

J Infect Dis. 2008 Oct 1;198(7):984-93. doi: 10.1086/591467.


Interferon and interferon-induced chemokine expression is associated with control of acute viremia in West Nile virus-infected blood donors.

Tobler LH, Cameron MJ, Lanteri MC, Prince HE, Danesh A, Persad D, Lanciotti RS, Norris PJ, Kelvin DJ, Busch MP.

J Infect Dis. 2008 Oct 1;198(7):979-83. doi: 10.1086/591466. Erratum in: J Infect Dis. 2008 Nov 15;198(10):1575.


Cost-effectiveness of implementation methods for ELISA serology testing of Trypanosoma cruzi in California blood banks.

Wilson LS, Ramsey JM, Koplowicz YB, Valiente-Banuet L, Motter C, Bertozzi SM, Tobler LH.

Am J Trop Med Hyg. 2008 Jul;79(1):53-68.


Health insurance coverage for young adults.

Tobler L.

NCSL Legisbrief. 2008 Jun-Jul;16(29):1-2. No abstract available.


Hepatitis C virus (HCV)-specific immune responses of long-term injection drug users frequently exposed to HCV.

Mizukoshi E, Eisenbach C, Edlin BR, Newton KP, Raghuraman S, Weiler-Normann C, Tobler LH, Busch MP, Carrington M, McKeating JA, O'Brien TR, Rehermann B.

J Infect Dis. 2008 Jul 15;198(2):203-12. doi: 10.1086/589510.


Dengue viremia in blood donors from Honduras, Brazil, and Australia.

Linnen JM, Vinelli E, Sabino EC, Tobler LH, Hyland C, Lee TH, Kolk DP, Broulik AS, Collins CS, Lanciotti RS, Busch MP.

Transfusion. 2008 Jul;48(7):1355-62. doi: 10.1111/j.1537-2995.2008.01772.x. Epub 2008 May 22.


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