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Items: 1 to 50 of 85

1.

Molecular profiling of failed endochondral ossification in mucopolysaccharidosis VII.

Peck SH, Tobias JW, Shore EM, Malhotra NR, Haskins ME, Casal ML, Smith LJ.

Bone. 2019 Aug 20;128:115042. doi: 10.1016/j.bone.2019.115042. [Epub ahead of print]

PMID:
31442675
2.

Tumor cell-intrinsic EPHA2 suppresses anti-tumor immunity by regulating PTGS2 (COX-2).

Markosyan N, Li J, Sun YH, Richman LP, Lin JH, Yan F, Quinones L, Sela Y, Yamazoe T, Gordon N, Tobias JW, Byrne KT, Rech AJ, FitzGerald GA, Stanger BZ, Vonderheide RH.

J Clin Invest. 2019 Jun 4;130:3594-3609. doi: 10.1172/JCI127755.

3.

RB constrains lineage fidelity and multiple stages of tumour progression and metastasis.

Walter DM, Yates TJ, Ruiz-Torres M, Kim-Kiselak C, Gudiel AA, Deshpande C, Wang WZ, Cicchini M, Stokes KL, Tobias JW, Buza E, Feldser DM.

Nature. 2019 May;569(7756):423-427. doi: 10.1038/s41586-019-1172-9. Epub 2019 May 1.

PMID:
31043741
4.

Hypoxic Preconditioning Enhances Bone Marrow-Derived Mesenchymal Stem Cell Survival in a Low Oxygen and Nutrient-Limited 3D Microenvironment.

Peck SH, Bendigo JR, Tobias JW, Dodge GR, Malhotra NR, Mauck RL, Smith LJ.

Cartilage. 2019 Apr 11:1947603519841675. doi: 10.1177/1947603519841675. [Epub ahead of print]

PMID:
30971109
5.

Fibrostenotic eosinophilic esophagitis might reflect epithelial lysyl oxidase induction by fibroblast-derived TNF-α.

Kasagi Y, Dods K, Wang JX, Chandramouleeswaran PM, Benitez AJ, Gambanga F, Kluger J, Ashorobi T, Gross J, Tobias JW, Klein-Szanto AJ, Spergel JM, Cianferoni A, Falk GW, Whelan KA, Nakagawa H, Muir AB.

J Allergy Clin Immunol. 2019 Jul;144(1):171-182. doi: 10.1016/j.jaci.2018.10.067. Epub 2018 Dec 20.

PMID:
30578874
6.

Genome-wide analyses and functional profiling of human NK cell lines.

Gunesch JT, Angelo LS, Mahapatra S, Deering RP, Kowalko JE, Sleiman P, Tobias JW, Monaco-Shawver L, Orange JS, Mace EM.

Mol Immunol. 2018 Jul 24. pii: S0161-5890(18)30556-X. doi: 10.1016/j.molimm.2018.07.015. [Epub ahead of print] Review.

PMID:
30054012
7.

Tumor Cell-Intrinsic Factors Underlie Heterogeneity of Immune Cell Infiltration and Response to Immunotherapy.

Li J, Byrne KT, Yan F, Yamazoe T, Chen Z, Baslan T, Richman LP, Lin JH, Sun YH, Rech AJ, Balli D, Hay CA, Sela Y, Merrell AJ, Liudahl SM, Gordon N, Norgard RJ, Yuan S, Yu S, Chao T, Ye S, Eisinger-Mathason TSK, Faryabi RB, Tobias JW, Lowe SW, Coussens LM, Wherry EJ, Vonderheide RH, Stanger BZ.

Immunity. 2018 Jul 17;49(1):178-193.e7. doi: 10.1016/j.immuni.2018.06.006. Epub 2018 Jun 26.

8.

Identification of p38 MAPK as a novel therapeutic target for Friedreich's ataxia.

Cotticelli MG, Xia S, Kaur A, Lin D, Wang Y, Ruff E, Tobias JW, Wilson RB.

Sci Rep. 2018 Mar 22;8(1):5007. doi: 10.1038/s41598-018-23168-x.

9.

The Esophageal Organoid System Reveals Functional Interplay Between Notch and Cytokines in Reactive Epithelial Changes.

Kasagi Y, Chandramouleeswaran PM, Whelan KA, Tanaka K, Giroux V, Sharma M, Wang J, Benitez AJ, DeMarshall M, Tobias JW, Hamilton KE, Falk GW, Spergel JM, Klein-Szanto AJ, Rustgi AK, Muir AB, Nakagawa H.

Cell Mol Gastroenterol Hepatol. 2018 Jan 3;5(3):333-352. doi: 10.1016/j.jcmgh.2017.12.013. eCollection 2018 Mar.

10.

Whole Transcriptome Analysis of Notochord-Derived Cells during Embryonic Formation of the Nucleus Pulposus.

Peck SH, McKee KK, Tobias JW, Malhotra NR, Harfe BD, Smith LJ.

Sci Rep. 2017 Sep 5;7(1):10504. doi: 10.1038/s41598-017-10692-5.

11.

Mutual reinforcement between telomere capping and canonical Wnt signalling in the intestinal stem cell niche.

Yang TB, Chen Q, Deng JT, Jagannathan G, Tobias JW, Schultz DC, Wang S, Lengner CJ, Rustgi AK, Lynch JP, Johnson FB.

Nat Commun. 2017 Mar 17;8:14766. doi: 10.1038/ncomms14766.

12.

Systematic In Vivo Inactivation of Chromatin-Regulating Enzymes Identifies Setd2 as a Potent Tumor Suppressor in Lung Adenocarcinoma.

Walter DM, Venancio OS, Buza EL, Tobias JW, Deshpande C, Gudiel AA, Kim-Kiselak C, Cicchini M, Yates TJ, Feldser DM.

Cancer Res. 2017 Apr 1;77(7):1719-1729. doi: 10.1158/0008-5472.CAN-16-2159. Epub 2017 Feb 15.

13.

Peripheral Blood Gene Expression Changes Associated With Primary Graft Dysfunction After Lung Transplantation.

Diamond JM, Cantu E, Porteous MK, Suzuki Y, Meyer KC, Lederer DJ, Milewski RK, Arcasoy S, D'Ovidio F, Bacchetta M, Sonett JR, Singh G, Costa J, Tobias JW, Rodriguez H, Van Deerlin VM, Olthoff KM, Shaked A, Chang BL, Christie JD; Clinical Trials in Organ Transplantation (CTOT)-03 Investigators.

Am J Transplant. 2017 Jul;17(7):1770-1777. doi: 10.1111/ajt.14209. Epub 2017 Feb 17.

14.

Age-Associated B Cells Express a Diverse Repertoire of VH and Vκ Genes with Somatic Hypermutation.

Russell Knode LM, Naradikian MS, Myles A, Scholz JL, Hao Y, Liu D, Ford ML, Tobias JW, Cancro MP, Gearhart PJ.

J Immunol. 2017 Mar 1;198(5):1921-1927. doi: 10.4049/jimmunol.1601106. Epub 2017 Jan 16.

15.

IL-10 distinguishes a unique population of activated, effector-like CD8+ T cells in murine acute liver inflammation.

Rood JE, Canna SW, Weaver LK, Tobias JW, Behrens EM.

J Leukoc Biol. 2017 Apr;101(4):1037-1044. doi: 10.1189/jlb.3A0916-221RR. Epub 2016 Dec 29.

16.

Heterogeneity in readouts of canonical wnt pathway activity within intestinal crypts.

Li N, Yousefi M, Nakauka-Ddamba A, Tobias JW, Jensen ST, Morrisey EE, Lengner CJ.

Dev Dyn. 2016 Aug;245(8):822-33. doi: 10.1002/dvdy.24423. Epub 2016 Jul 5.

17.

Methylation Microarray Studies Highlight PDGFA Expression as a Factor in Biliary Atresia.

Cofer ZC, Cui S, EauClaire SF, Kim C, Tobias JW, Hakonarson H, Loomes KM, Matthews RP.

PLoS One. 2016 Mar 24;11(3):e0151521. doi: 10.1371/journal.pone.0151521. eCollection 2016.

18.

High-definition CpG methylation of novel genes in gastric carcinogenesis identified by next-generation sequencing.

Sepulveda JL, Gutierrez-Pajares JL, Luna A, Yao Y, Tobias JW, Thomas S, Woo Y, Giorgi F, Komissarova EV, Califano A, Wang TC, Sepulveda AR.

Mod Pathol. 2016 Feb;29(2):182-93. doi: 10.1038/modpathol.2015.144. Epub 2016 Jan 15.

19.

Genetic Response of Rat Supraspinatus Tendon and Muscle to Exercise.

Rooney SI, Tobias JW, Bhatt PR, Kuntz AF, Soslowsky LJ.

PLoS One. 2015 Oct 8;10(10):e0139880. doi: 10.1371/journal.pone.0139880. eCollection 2015.

20.

Iron-induced Local Complement Component 3 (C3) Up-regulation via Non-canonical Transforming Growth Factor (TGF)-β Signaling in the Retinal Pigment Epithelium.

Li Y, Song D, Song Y, Zhao L, Wolkow N, Tobias JW, Song W, Dunaief JL.

J Biol Chem. 2015 May 8;290(19):11918-34. doi: 10.1074/jbc.M115.645903. Epub 2015 Mar 23.

21.

Genome wide nucleosome mapping for HSV-1 shows nucleosomes are deposited at preferred positions during lytic infection.

Oh J, Sanders IF, Chen EZ, Li H, Tobias JW, Isett RB, Penubarthi S, Sun H, Baldwin DA, Fraser NW.

PLoS One. 2015 Feb 24;10(2):e0117471. doi: 10.1371/journal.pone.0117471. eCollection 2015.

22.

Nodal pathway genes are down-regulated in facial asymmetry.

Nicot R, Hottenstein M, Raoul G, Ferri J, Horton M, Tobias JW, Barton E, Gelé P, Sciote JJ.

J Craniofac Surg. 2014 Nov;25(6):e548-55. doi: 10.1097/SCS.0000000000001076.

23.

The Notch1 transcriptional activation domain is required for development and reveals a novel role for Notch1 signaling in fetal hematopoietic stem cells.

Gerhardt DM, Pajcini KV, D'altri T, Tu L, Jain R, Xu L, Chen MJ, Rentschler S, Shestova O, Wertheim GB, Tobias JW, Kluk M, Wood AW, Aster JC, Gimotty PA, Epstein JA, Speck N, Bigas A, Pear WS.

Genes Dev. 2014 Mar 15;28(6):576-93. doi: 10.1101/gad.227496.113.

24.

Novel MAPK-dependent and -independent tubulogenes identified via microarray analysis of 3D-cultured Madin-Darby canine kidney cells.

Chacon-Heszele MF, Zuo X, Hellman NE, McKenna S, Choi SY, Huang L, Tobias JW, Park KM, Lipschutz JH.

Am J Physiol Renal Physiol. 2014 May 1;306(9):F1047-58. doi: 10.1152/ajprenal.00589.2013. Epub 2014 Feb 26.

25.

Alterations of pancreatic islet structure, metabolism and gene expression in diet-induced obese C57BL/6J mice.

Roat R, Rao V, Doliba NM, Matschinsky FM, Tobias JW, Garcia E, Ahima RS, Imai Y.

PLoS One. 2014 Feb 5;9(2):e86815. doi: 10.1371/journal.pone.0086815. eCollection 2014.

26.

Identification of Pax3 and Zic1 targets in the developing neural crest.

Bae CJ, Park BY, Lee YH, Tobias JW, Hong CS, Saint-Jeannet JP.

Dev Biol. 2014 Feb 15;386(2):473-83. doi: 10.1016/j.ydbio.2013.12.011. Epub 2013 Dec 17.

27.

Malignant transformation of CD4+ T lymphocytes mediated by oncogenic kinase NPM/ALK recapitulates IL-2-induced cell signaling and gene expression reprogramming.

Marzec M, Halasa K, Liu X, Wang HY, Cheng M, Baldwin D, Tobias JW, Schuster SJ, Woetmann A, Zhang Q, Turner SD, Ødum N, Wasik MA.

J Immunol. 2013 Dec 15;191(12):6200-7. doi: 10.4049/jimmunol.1300744. Epub 2013 Nov 11.

28.

Gene expression profiling to predict viridans group streptococcal and invasive fungal infection in pediatric acute myeloid leukemia: a brief report from the Children's Oncology Group.

Lee GE, Sung L, Fisher BT, Sullivan KE, McWilliams T, Tobias JW, Meshinchi S, Alonzo TA, Gamis A, Aplenc R.

Acta Haematol. 2014;131(3):167-9. doi: 10.1159/000353758. Epub 2013 Nov 6. No abstract available.

29.

Gene set enrichment analysis identifies key innate immune pathways in primary graft dysfunction after lung transplantation.

Cantu E, Lederer DJ, Meyer K, Milewski K, Suzuki Y, Shah RJ, Diamond JM, Meyer NJ, Tobias JW, Baldwin DA, Van Deerlin VM, Olthoff KM, Shaked A, Christie JD; CTOT Investigators.

Am J Transplant. 2013 Jul;13(7):1898-904. doi: 10.1111/ajt.12283. Epub 2013 May 24.

30.

MicroRNA expression profiles of seminoma from paraffin-embedded formalin-fixed tissue.

Bing Z, Master SR, Tobias JW, Baldwin DA, Xu XW, Tomaszewski JE.

Virchows Arch. 2012 Dec;461(6):663-8. doi: 10.1007/s00428-012-1325-9. Epub 2012 Oct 14.

PMID:
23064661
31.

Microarray analysis of murine retinal light damage reveals changes in iron regulatory, complement, and antioxidant genes in the neurosensory retina and isolated RPE.

Hadziahmetovic M, Kumar U, Song Y, Grieco S, Song D, Li Y, Tobias JW, Dunaief JL.

Invest Ophthalmol Vis Sci. 2012 Aug 7;53(9):5231-41. doi: 10.1167/iovs.12-10204.

32.

Fertile offspring derived from mouse spermatogonial stem cells cryopreserved for more than 14 years.

Wu X, Goodyear SM, Abramowitz LK, Bartolomei MS, Tobias JW, Avarbock MR, Brinster RL.

Hum Reprod. 2012 May;27(5):1249-59. doi: 10.1093/humrep/des077. Epub 2012 Mar 12.

33.

MiRNA-9 and MiRNA-200a distinguish hemangioblastomas from metastatic clear cell renal cell carcinomas in the CNS.

Venneti S, Boateng LA, Friedman JR, Baldwin DA, Tobias JW, Judkins AR, Mourelatos Z, Lal P.

Brain Pathol. 2012 Jul;22(4):522-9. doi: 10.1111/j.1750-3639.2011.00551.x. Epub 2011 Dec 9.

PMID:
22082152
34.

Spermatogonial stem cell self-renewal requires ETV5-mediated downstream activation of Brachyury in mice.

Wu X, Goodyear SM, Tobias JW, Avarbock MR, Brinster RL.

Biol Reprod. 2011 Dec;85(6):1114-23. doi: 10.1095/biolreprod.111.091793. Epub 2011 Aug 3.

35.

MicroRNA-21 regulates the self-renewal of mouse spermatogonial stem cells.

Niu Z, Goodyear SM, Rao S, Wu X, Tobias JW, Avarbock MR, Brinster RL.

Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12740-5. doi: 10.1073/pnas.1109987108. Epub 2011 Jul 18.

36.

Image defocus and altered retinal gene expression in chick: clues to the pathogenesis of ametropia.

Stone RA, McGlinn AM, Baldwin DA, Tobias JW, Iuvone PM, Khurana TS.

Invest Ophthalmol Vis Sci. 2011 Jul 29;52(8):5765-77. doi: 10.1167/iovs.10-6727.

37.

In vivo profiling of hypoxic gene expression in gliomas using the hypoxia marker EF5 and laser-capture microdissection.

Marotta D, Karar J, Jenkins WT, Kumanova M, Jenkins KW, Tobias JW, Baldwin D, Hatzigeorgiou A, Alexiou P, Evans SM, Alarcon R, Maity A, Koch C, Koumenis C.

Cancer Res. 2011 Feb 1;71(3):779-89. doi: 10.1158/0008-5472.CAN-10-3061. Epub 2011 Jan 25.

38.

Bald scalp in men with androgenetic alopecia retains hair follicle stem cells but lacks CD200-rich and CD34-positive hair follicle progenitor cells.

Garza LA, Yang CC, Zhao T, Blatt HB, Lee M, He H, Stanton DC, Carrasco L, Spiegel JH, Tobias JW, Cotsarelis G.

J Clin Invest. 2011 Feb;121(2):613-22. doi: 10.1172/JCI44478. Epub 2011 Jan 4.

39.

In vivo and in vitro aging is detrimental to mouse spermatogonial stem cell function.

Schmidt JA, Abramowitz LK, Kubota H, Wu X, Niu Z, Avarbock MR, Tobias JW, Bartolomei MS, Brinster RL.

Biol Reprod. 2011 Apr;84(4):698-706. doi: 10.1095/biolreprod.110.088229. Epub 2010 Dec 29.

40.

Esophageal squamous cell dysplasia and delayed differentiation with deletion of krüppel-like factor 4 in murine esophagus.

Tetreault MP, Yang Y, Travis J, Yu QC, Klein-Szanto A, Tobias JW, Katz JP.

Gastroenterology. 2010 Jul;139(1):171-81.e9. doi: 10.1053/j.gastro.2010.03.048. Epub 2010 Mar 27.

41.

Hypoxia activates the cyclooxygenase-2-prostaglandin E synthase axis.

Lee JJ, Natsuizaka M, Ohashi S, Wong GS, Takaoka M, Michaylira CZ, Budo D, Tobias JW, Kanai M, Shirakawa Y, Naomoto Y, Klein-Szanto AJ, Haase VH, Nakagawa H.

Carcinogenesis. 2010 Mar;31(3):427-34. doi: 10.1093/carcin/bgp326. Epub 2009 Dec 30.

42.

Prepubertal human spermatogonia and mouse gonocytes share conserved gene expression of germline stem cell regulatory molecules.

Wu X, Schmidt JA, Avarbock MR, Tobias JW, Carlson CA, Kolon TF, Ginsberg JP, Brinster RL.

Proc Natl Acad Sci U S A. 2009 Dec 22;106(51):21672-7. doi: 10.1073/pnas.0912432106. Epub 2009 Dec 14.

43.

Lack of TNFalpha expression protects anaplastic lymphoma kinase-positive T-cell lymphoma (ALK+ TCL) cells from apoptosis.

Zhang Q, Wang HY, Bhutani G, Liu X, Paessler M, Tobias JW, Baldwin D, Swaminathan K, Milone MC, Wasik MA.

Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15843-8. doi: 10.1073/pnas.0907070106. Epub 2009 Aug 26.

44.

Identification of a putative network of actin-associated cytoskeletal proteins in glomerular podocytes defined by co-purified mRNAs.

Nabet B, Tsai A, Tobias JW, Carstens RP.

PLoS One. 2009 Aug 4;4(8):e6491. doi: 10.1371/journal.pone.0006491.

45.

MicroRNA expression profiling outperforms mRNA expression profiling in formalin-fixed paraffin-embedded tissues.

Liu A, Tetzlaff MT, Vanbelle P, Elder D, Feldman M, Tobias JW, Sepulveda AR, Xu X.

Int J Clin Exp Pathol. 2009 Mar 20;2(6):519-27.

46.

Identification of glial cell line-derived neurotrophic factor-regulated genes important for spermatogonial stem cell self-renewal in the rat.

Schmidt JA, Avarbock MR, Tobias JW, Brinster RL.

Biol Reprod. 2009 Jul;81(1):56-66. doi: 10.1095/biolreprod.108.075358. Epub 2009 Apr 1.

47.

Colony stimulating factor 1 is an extrinsic stimulator of mouse spermatogonial stem cell self-renewal.

Oatley JM, Oatley MJ, Avarbock MR, Tobias JW, Brinster RL.

Development. 2009 Apr;136(7):1191-9. doi: 10.1242/dev.032243.

48.

HFR1 is crucial for transcriptome regulation in the cryptochrome 1-mediated early response to blue light in Arabidopsis thaliana.

Zhang XN, Wu Y, Tobias JW, Brunk BP, Deitzer GF, Liu D.

PLoS One. 2008;3(10):e3563. doi: 10.1371/journal.pone.0003563. Epub 2008 Oct 30.

49.

Cdx1 and c-Myc foster the initiation of transdifferentiation of the normal esophageal squamous epithelium toward Barrett's esophagus.

Stairs DB, Nakagawa H, Klein-Szanto A, Mitchell SD, Silberg DG, Tobias JW, Lynch JP, Rustgi AK.

PLoS One. 2008;3(10):e3534. doi: 10.1371/journal.pone.0003534. Epub 2008 Oct 27.

50.

Analysis of gene expression in pancreatic islets from diet-induced obese mice.

Imai Y, Patel HR, Doliba NM, Matschinsky FM, Tobias JW, Ahima RS.

Physiol Genomics. 2008 Dec 12;36(1):43-51. doi: 10.1152/physiolgenomics.00050.2008. Epub 2008 Oct 14.

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