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Items: 13


Modeling Complex Neurological Diseases with Stem Cells: A Study of Bipolar Disorder.

Pernia CD, Nathan NH, Tobe BTD, Winquist AM, Sidman RL, Goshima Y, Snyder EY.

Results Probl Cell Differ. 2018;66:265-282. doi: 10.1007/978-3-319-93485-3_12.


Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis.

Tobe BTD, Crain AM, Winquist AM, Calabrese B, Makihara H, Zhao WN, Lalonde J, Nakamura H, Konopaske G, Sidor M, Pernia CD, Yamashita N, Wada M, Inoue Y, Nakamura F, Sheridan SD, Logan RW, Brandel M, Wu D, Hunsberger J, Dorsett L, Duerr C, Basa RCB, McCarthy MJ, Udeshi ND, Mertins P, Carr SA, Rouleau GA, Mastrangelo L, Li J, Gutierrez GJ, Brill LM, Venizelos N, Chen G, Nye JS, Manji H, Price JH, McClung CA, Akiskal HS, Alda M, Chuang DM, Coyle JT, Liu Y, Teng YD, Ohshima T, Mikoshiba K, Sidman RL, Halpain S, Haggarty SJ, Goshima Y, Snyder EY.

Proc Natl Acad Sci U S A. 2017 May 30;114(22):E4462-E4471. doi: 10.1073/pnas.1700111114. Epub 2017 May 12.


Quantitative Analysis of Human Pluripotency and Neural Specification by In-Depth (Phospho)Proteomic Profiling.

Singec I, Crain AM, Hou J, Tobe BTD, Talantova M, Winquist AA, Doctor KS, Choy J, Huang X, La Monaca E, Horn DM, Wolf DA, Lipton SA, Gutierrez GJ, Brill LM, Snyder EY.

Stem Cell Reports. 2016 Sep 13;7(3):527-542. doi: 10.1016/j.stemcr.2016.07.019. Epub 2016 Aug 25.


Implications and limitations of cellular reprogramming for psychiatric drug development.

Tobe BT, Brandel MG, Nye JS, Snyder EY.

Exp Mol Med. 2013 Nov 15;45:e59. doi: 10.1038/emm.2013.124. Review.


Combined total proteomic and phosphoproteomic analysis of human pluripotent stem cells.

Hou J, Tobe BT, Lo F, Blethrow JD, Crain AM, Wolf DA, Snyder EY, Singec I, Brill LM.

Methods Mol Biol. 2013;1029:163-89. doi: 10.1007/978-1-62703-478-4_12.


Three-dimensional scaffolding to investigate neuronal derivatives of human embryonic stem cells.

Soman P, Tobe BTD, Lee JW, Winquist AM, Singec I, Vecchio KS, Snyder EY, Chen S.

Biomed Microdevices. 2012 Oct;14(5):829-838. doi: 10.1007/s10544-012-9662-7.


Phosphoproteomic analysis: an emerging role in deciphering cellular signaling in human embryonic stem cells and their differentiated derivatives.

Tobe BT, Hou J, Crain AM, Singec I, Snyder EY, Brill LM.

Stem Cell Rev Rep. 2012 Mar;8(1):16-31. doi: 10.1007/s12015-011-9317-8. Review.


Modeling complex neuropsychiatric disorders with human induced pluripotent stem cells.

Tobe BT, Snyder EY, Nye JS.

Curr Opin Pharmacol. 2011 Oct;11(5):521-7. doi: 10.1016/j.coph.2011.05.007. Epub 2011 Jun 29. Review.


Morphogenesis signaling components influence cell cycle regulation by cyclin dependent kinase.

Tobe BT, Kitazono AA, Garcia JS, Gerber RA, Bevis BJ, Choy JS, Chasman D, Kron SJ.

Cell Div. 2009 Jul 1;4:12. doi: 10.1186/1747-1028-4-12.


Marker-fusion PCR for one-step mutagenesis of essential genes in yeast.

Kitazono AA, Tobe BT, Kalton H, Diamant N, Kron SJ.

Yeast. 2002 Jan 30;19(2):141-9.


Cell cycle control of yeast filamentous growth.

Rua D, Tobe BT, Kron SJ.

Curr Opin Microbiol. 2001 Dec;4(6):720-7. Review.


Enhanced cell polarity in mutants of the budding yeast cyclin-dependent kinase Cdc28p.

Ahn SH, Tobe BT, Fitz Gerald JN, Anderson SL, Acurio A, Kron SJ.

Mol Biol Cell. 2001 Nov;12(11):3589-600.


Yng2p-dependent NuA4 histone H4 acetylation activity is required for mitotic and meiotic progression.

Choy JS, Tobe BT, Huh JH, Kron SJ.

J Biol Chem. 2001 Nov 23;276(47):43653-62. Epub 2001 Sep 5.

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