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Items: 14

1.

Oncogenic D816V-KIT signaling in mast cells causes persistent IL-6 production.

Tobío A, Bandara G, Morris DA, Kim DK, O'Connell MP, Komarow HD, Carter MC, Smrz D, Metcalfe DD, Olivera A.

Haematologica. 2020 Jan;105(1):124-135. doi: 10.3324/haematol.2018.212126. Epub 2019 Apr 4.

2.

Targeting Sphingosine Kinase Isoforms Effectively Reduces Growth and Survival of Neoplastic Mast Cells With D816V-KIT.

Bandara G, Muñoz-Cano R, Tobío A, Yin Y, Komarow HD, Desai A, Metcalfe DD, Olivera A.

Front Immunol. 2018 Mar 28;9:631. doi: 10.3389/fimmu.2018.00631. eCollection 2018.

3.

Yessotoxin, a Marine Toxin, Exhibits Anti-Allergic and Anti-Tumoural Activities Inhibiting Melanoma Tumour Growth in a Preclinical Model.

Tobío A, Alfonso A, Madera-Salcedo I, Botana LM, Blank U.

PLoS One. 2016 Dec 14;11(12):e0167572. doi: 10.1371/journal.pone.0167572. eCollection 2016.

4.

Identification of Biological and Pharmaceutical Mast Cell- and Basophil-Related Targets.

Klein O, Ngo-Nyekel F, Stefanache T, Torres R, Salomonsson M, Hallgren J, Rådinger M, Bambouskova M, Campbell M, Cohen-Mor S, Dema B, Rose CG, Abrink M, Charles N, Ainooson G, Paivandy A, Pavlova VG, Serrano-Candelas E, Yu Y, Hellman L, Jensen BM, Van Anrooij B, Grootens J, Gura HK, Stylianou M, Tobio A, Blank U, Öhrvik H, Maurer M.

Scand J Immunol. 2016 Jun;83(6):465-72. doi: 10.1111/sji.12436. No abstract available.

5.

C-kit mutations determine dasatinib mechanism of action in HMC-1 neoplastic mast cells: dasatinib differently regulates PKCδ translocation in HMC-1(560) and HMC-1(560,816) cell lines.

Tobío A, Alfonso A, Botana LM.

Immunopharmacol Immunotoxicol. 2015;37(4):380-7. doi: 10.3109/08923973.2015.1064132. Epub 2015 Jul 16.

PMID:
26181649
6.

Cross-talks between c-Kit and PKC isoforms in HMC-1(560) and HMC-1(560,816) cells. Different role of PKCδ in each cellular line.

Tobío A, Alfonso A, Botana LM.

Cell Immunol. 2015 Feb;293(2):104-12. doi: 10.1016/j.cellimm.2014.12.004. Epub 2014 Dec 23.

7.

PKC potentiates tyrosine kinase inhibitors STI571 and dasatinib cytotoxic effect.

Tobío A, Alfonso A, Botana LM.

Anticancer Res. 2014 Jul;34(7):3347-56.

PMID:
24982339
8.

Role of AKAP 149-PKA-PDE4A complex in cell survival and cell differentiation processes.

Fernández-Araujo A, Tobío A, Alfonso A, Botana LM.

Int J Biochem Cell Biol. 2014 Aug;53:89-101. doi: 10.1016/j.biocel.2014.04.028. Epub 2014 May 9.

PMID:
24813785
9.

Surface plasmon resonance biosensor method for palytoxin detection based on Na+,K+-ATPase affinity.

Alfonso A, Pazos MJ, Fernández-Araujo A, Tobio A, Alfonso C, Vieytes MR, Botana LM.

Toxins (Basel). 2013 Dec 27;6(1):96-107. doi: 10.3390/toxins6010096.

10.

Different role of cAMP pathway on the human mast cells HMC-1(560) and HMC-1(560,816) activation.

Barreiro-Costa O, Tobío A, Alfonso A, Botana LM.

J Cell Biochem. 2014 May;115(5):896-909. doi: 10.1002/jcb.24732.

PMID:
24307603
11.

Protein kinase C modulates Aurora-kinase inhibition induced by CCT129202 in HMC-1⁵⁶⁰,⁸¹⁶ cell line.

Tobío A, Alfonso A, Fernández-Araujo A, Alonso E, Botana LM.

Antiinflamm Antiallergy Agents Med Chem. 2013;12(3):265-76.

PMID:
23701310
12.

Role of yessotoxin in calcium and cAMP-crosstalks in primary and K-562 human lymphocytes: the effect is mediated by anchor kinase A mitochondrial proteins.

Tobío A, Fernández-Araujo A, Alfonso A, Botana LM.

J Cell Biochem. 2012 Dec;113(12):3752-61. doi: 10.1002/jcb.24249.

PMID:
22807343
13.

Palytoxin detection and quantification using the fluorescence polarization technique.

Alfonso A, Fernández-Araujo A, Alfonso C, Caramés B, Tobio A, Louzao MC, Vieytes MR, Botana LM.

Anal Biochem. 2012 May 1;424(1):64-70. doi: 10.1016/j.ab.2012.02.014. Epub 2012 Feb 25.

PMID:
22370274
14.

C-kit mutations and PKC crosstalks: PKC translocates to nucleous only in cells HMC⁵⁶⁰,⁸¹⁶.

Tobío A, Alfonso A, Botana LM.

J Cell Biochem. 2011 Sep;112(9):2637-51. doi: 10.1002/jcb.23191.

PMID:
21598306

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